Substance P inhibits pancreatic ductal bicarbonate secretion via neurokinin receptors 2 and 3 in the guinea pig exocrine pancreas

Pancreas

Volumn 40, Issue 5, 2011, Pages 793-795

  Kemény, Lajos V ^a   Hegyi, Péter ^a   Rakonczay Jr , Zoltán ^a   Borka, Katalin ^b   Korompay, Anna ^b   Gray, Mike A ^c   Argent, Barry E ^c   Venglovecz, Viktória ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; AMMONIUM CHLORIDE; BICARBONATE; N [ALPHA (METHOXYCARBONYL)BENZYL] 2 PHENYL 4 QUINOLINECARBOXAMIDE; NEUROKININ 2 RECEPTOR; NEUROKININ A [4-10][5 TYROSINE 6,8,9 DEXTRO TRYPTOPHAN 10 LYSINE]; SUBSTANCE P;

ANIMAL CELL; EXPERIMENTAL GUINEA PIG; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; INHIBITION KINETICS; LETTER; MICROFLUOROMETRY; NONHUMAN; PANCREAS DUCT; PANCREAS SECRETION; PH; PRIORITY JOURNAL; SECRETION; SECRETORY PATHWAY;

ANIMALS; BICARBONATES; GUINEA PIGS; NEUROKININ A; PANCREAS, EXOCRINE; PANCREATIC DUCTS; PEPTIDE FRAGMENTS; QUINOLINES; RECEPTORS, NEUROKININ-2; RECEPTORS, NEUROKININ-3; SECRETIN; SUBSTANCE P;

EID: 79959837344     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3182161d05     Document Type: Letter

References (6)

1. Ashton N, Argent BE, Green R. Effect of vasoactive intestinal peptide, bombesin and substance P on fluid secretion by isolated rat pancreatic ducts.JPhysiol. 1990;427:471-482. (Pubitemid 20256737)
2. Hegyi P, Gray MA, Argent BE. Substance P inhibits bicarbonate secretion from guinea pig pancreatic ducts by modulating an anion exchanger. Am J Physiol Cell Physiol. 2003;285:C268YC276. (Pubitemid 36917841)
3. Hegyi P, Rakonczay Z Jr. The inhibitory pathways of pancreatic ductal bicarbonate secretion. Int J Biochem Cell Biol. 2007;39:25-30. (Pubitemid 44548446)
4. Henry J. Discussion of nomenclature for tachykinins and tachykinin receptors. In: Henry J, Couture R, Cuello AC, et al, eds. Substance Pand Neurokinins. New York, NY: Springer-Verlag; 1987:17-18.
5. Argent BE, Arkle S, Cullen MJ, et al. Morphological, biochemical and secretory studies on rat pancreatic ducts maintained in tissue culture. Q J Exp Physiol. 1986;71:633-648. (Pubitemid 17208273)
6. Hegyi P, Rakonczay Z Jr, Gray MA, et al. Measurement of intracellular pH in pancreatic duct cells: A new method for calibrating the fluorescence data. Pancreas. 2004;28:427-434. (Pubitemid 38509748)