Fatal invasive infection with fungemia due to Microascus cirrosus after heart and lung transplantation in a patient with cystic fibrosis

Journal of Clinical Microbiology

Volumn 49, Issue 7, 2011, Pages 2743-2747

  Miossec, Charline ^a   Morio, Florent ^a,b   Lepoivre, Thierry ^c   Le Pape, Patrice ^a,b   Garcia Hermoso, Dea ^d,e   Gay Andrieu, Françoise ^a,b   Haloun, Alain ^c   Treilhaud, Michele ^c   Leclair, François ^c   Miegeville, Michel ^a,b  

^a HÔTEL DIEU   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c NANTES UNIVERSITY HOSPITAL   (France)

^d INSTITUT PASTEUR   (France)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; BASILIXIMAB; CASPOFUNGIN; CYCLOSPORIN; FLUCONAZOLE; ITRACONAZOLE; METHYLPREDNISOLONE SODIUM SUCCINATE; POSACONAZOLE; RIBOSOME DNA; TERBINAFINE; VORICONAZOLE;

ADULT; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; CANDIDIASIS; CARDIAC GRAFT REJECTION; CASE REPORT; DEATH; DNA SEQUENCE; FUNGAL STRAIN; FUNGEMIA; FUNGUS CULTURE; HEART TRANSPLANTATION; HOSPITAL ADMISSION; HUMAN; LUNG FIBROSIS; LUNG GRAFT REJECTION; LUNG TRANSPLANTATION; MALE; MICROASCUS; MICROASCUS CIRROSUS; MINIMUM INHIBITORY CONCENTRATION; MULTIPLE ORGAN FAILURE; NUCLEOTIDE SEQUENCE; PLEURA EFFUSION; PNEUMOMEDIASTINUM; PNEUMOTHORAX; PRIORITY JOURNAL; RADIODENSITOMETRY; RARE SPECIES; SCOPULARIOPSIS; SPUTUM CULTURE;

ADULT; ANTIFUNGAL AGENTS; ASCOMYCOTA; CYSTIC FIBROSIS; DNA, FUNGAL; ECHINOCANDINS; FATAL OUTCOME; FUNGEMIA; HEART TRANSPLANTATION; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOCOMPROMISED HOST; LUNG TRANSPLANTATION; MALE; MICROSCOPY; MOLECULAR SEQUENCE DATA; MYCOSES; PLEURA; PYRIMIDINES; RADIOGRAPHY, THORACIC; SEQUENCE ANALYSIS, DNA; TOMOGRAPHY, X-RAY COMPUTED; TRIAZOLES;

MICROASCUS CIRROSUS; SCOPULARIOPSIS;

EID: 79959836062     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00127-11     Document Type: Article

References (34)

1. Aguilar, C., I. Pujol, and J. Guarro. 1999. In vitro antifungal susceptibilities of Scopulariopsis isolates. Antimicrob. Agents Chemother. 43:1520-1522.
2. Baddley, J. W., S. A. Moser, D. A. Sutton, and P. G. Pappas. 2000. Microascus cinereus (anamorph Scopulariopsis) brain abscess in a bone marrow transplant recipient. J. Clin. Microbiol. 38:395-397.
3. Beltrame, A., et al. 2009. A fatal case of invasive fungal sinusitis by Scopulariopsis acremonium in a bone marrow transplant recipient. Int. J. Infect. Dis. 13:e488-e492.
4. Bonifaz, A., P. Cruz-Aguilar, and R. M. Ponce. 2007. Onychomycosis by molds. Report of 78 cases. Eur. J. Dermatol. 17:70-72.
5. Cuenca-Estrella, M., et al. 2003. Scopulariopsis brevicaulis, a fungal pathogen resistant to broad-spectrum antifungal agents. Antimicrob. Agents Chemother. 47:2339-2341.
6. Cuenca-Estrella, M., et al. 2006. In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis. Antimicrob. Agents Chemother. 50:2248-2250.
7. De Hoog, G. S., J. Guarro, J. Gene, and M. J. Figueres. 2000. Atlas of clinical fungi, 2nd ed. Centraalbureau voor Schimmelcultures, Utrecht, the Netherlands.
8. De Pauw, B., et al. 2008. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin. Infect. Dis. 46:1813-1821.
9. Filipello Marchisio, V., A. Fusconi, and F. L. Querio. 2000. Scopulariopsis brevicaulis: a keratinophilic or a keratinolytic fungus? Mycoses 43:281-292.
10. Garcia-Effron, G., et al. 2004. In vitro activity of terbinafine against medically important non-dermatophyte species of filamentous fungi. J. Antimicrob. Chemother. 53:1086-1089.
11. Hart, A. P., D. A. Sutton, P. J. McFeeley, and M. Kornfeld. 2001. Cerebral phaeohyphomycosis caused by a dematiaceous Scopulariopsis species. Clin. Neuropathol. 20:224-228.
12. Isidro, A. M., et al. 2006. Fungal prosthetic mitral valve endocarditis caused by Scopulariopsis species: case report and review of the literature. J. Thorac. Cardiovasc. Surg. 131:1181-1183.
13. Kontoyiannis, D. P., et al. 2010. Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. Clin. Infect. Dis. 50:1091-1100.
14. Kriesel, J. D., E. E. Adderson, W. M. Gooch III, and A. T. Pavia. 1994. Invasive sinonasal disease due to Scopulariopsis candida: case report and review of scopulariopsosis. Clin. Infect. Dis. 19:317-319.
15. Krisher, K. K., N. B. Holdridge, M. M. Mustafa, M. G. Rinaldi, and D. A. McGough. 1995. Disseminated Microascus cirrosus infection in pediatric bone marrow transplant recipients. J. Clin. Microbiol. 33:735-737.
16. Neglia, J. P., D. D. Hurd, P. Ferrieri, and D. C. Snover. 1987. Invasive Scopulariopsis in the immunocompromised host. Am. J. Med. 83:1163-1166.
17. Nishimura, K., and M. Miyaji. 1985. Dimorphism of Microascus cirrosus. Mycopathologia 90:29-33. (Pubitemid 15055052)
18. Nwabuisi, C., A. K. Salami, N. A. Abdullahi, and O. O. Agbede. 2003. Scopulariopsis associated meningitis in adult Nigerian AIDS patient-a case report. West. Afr. J. Med. 22:364-365.
19. Pappas, P. G., et al. 2010. Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). Clin. Infect. Dis. 50:1101-1111.
20. Patel, R., et al. 1994. Phaeohyphomycosis due to Scopulariopsis brumptii in a liver transplant recipient. Clin. Infect. Dis. 19:198-200.
21. Rodriguez-Tudela, J. L., et al. 2008. EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia-forming moulds. Clin. Microbiol. Infect. 14:982-984.
22. Salmon, A., et al. 2010. Disseminated Scopulariopsis brevicaulis infection in an allogeneic stem cell recipient: case report and review of the literature. Clin. Microbiol. Infect. 16:508-512.
23. Sellami, A., et al. 2003. Infection disséminée à Scopulariopsis brevicaulis. J. Mycol. Med. 13:203-206.
24. Singh, N., and S. Husain. 2003. Aspergillus infections after lung transplantation: clinical differences in type of transplant and implications for management. J. Heart Lung Transplant. 22:258-266. (Pubitemid 36300817)
25. Steinbach, W. J., and D. A. Stevens. 2003. Review of newer antifungal and immunomodulatory strategies for invasive aspergillosis. Clin. Infect. Dis. 37:S157-S187.
26. Steinbach, W. J., W. A. Schell, J. L. Miller, J. R. Perfect, and P. L. Martin. 2004. Fatal Scopulariopsis brevicaulis infection in a paediatric stem-cell transplant patient treated with voriconazole and caspofungin and a review of Scopulariopsis infections in immunocompromised patients. J. Infect. 48:112-116.
27. Stevens, D. A., E. Brummer, and K. V. Clemons. 2006. Interferon-gamma as an antifungal. J. Infect. Dis. 194:S33-S37.
28. Swick, B. L., S. C. Reddy, A. Friedrichs, and M. S. Stone. 2010. Disseminated Scopulariopsis-culture is required to distinguish from other disseminated mould infections. J. Cutan. Pathol. 37:687-691.
29. Tong, Z., et al. 2007. In vitro activities of miltefosine and two novel antifungal biscationic salts against a panel of 77 dermatophytes. Antimicrob. Agents Chemother. 51:2219-2222.
30. Ustun, C., G. Huls, M. Stewart, and K. A. Marr. 2006. Resistant Microascus cirrosus pneumonia can be treated with a combination of surgery, multiple anti-fungal agents and a growth factor. Mycopathologia 162:299-302.
31. Vaidya, P. S., and J. F. Levine. 1992. Scopulariopsis peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis. Perit. Dial. Int. 12:78-79.
32. Walsh, T. J., et al. 2004. Infections due to emerging and uncommon medically important fungal pathogens. Clin. Microbiol. Infect. 10:48-66.
33. Widmer, F., et al. 2006. Hexadecylphosphocholine (miltefosine) has broadspectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis. Antimicrob. Agents Chemother. 50:414-421.
34. Wuyts, W. A., et al. 2005. Fatal Scopulariopsis infection in a lung transplant recipient: a case report. J. Heart Lung Transplant. 24:2301-2304. (Pubitemid 41814762)