A case of non-small cell lung cancer with EGFR mutation responding to S-1 after a therapy with gefitinib

Japanese Journal of Cancer and Chemotherapy

Volumn 36, Issue 4, 2009, Pages 675-677

  Kawano, Osamu ^a   Yano, Motoki ^a   Sasaki, Hidefumi ^a   Yukiue, Haruhiro ^a   Okuda, Katsuhiro ^a   Fujii, Yoshitaka ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Gefitinib; Non small cell lung cancer; S 1

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; GIMERACIL PLUS OTERACIL POTASSIUM PLUS TEGAFUR; UFT;

ABSENCE OF SIDE EFFECTS; AGED; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; GENE MUTATION; HUMAN; LUNG ADENOCARCINOMA; LUNG LOBECTOMY; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; MALE; TREATMENT RESPONSE;

EID: 79959823714     PISSN: 03850684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Furuse K, Kawase M, Hasegawa K, et al: Early phase II study of S-1, a new oral fluoropyrimidine, for advanced non-small-cell lung cancer. Int J Clin Oncol 6(5):236-241, 2001.
2. Kawahara M, Furuse K, Segawa Y, et al: Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer. Br J Cancer 85(7):939-943, 2001. (Pubitemid 33015993)
3. Ichinose Y, Yoshimori K, Sakai H, et al: S-1 plus cisplatin combination chemotherapy in patients with advanced non-small cell lung cancer: a multi-institutional phase II trial. Clin Cancer Res 10(23):7860-7864, 2004. (Pubitemid 39587524)
4. Magné N, Fischel JL, Dubreuil A, et al: ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: rational basis for a new combination therapy with capecitabine. Clin Cancer Res 9(13):4735-4742, 2003. (Pubitemid 37323276)
5. Okabe T, Okamoto I, Tsukioka S, et al: Synergistic antitumor effect of S-1 and the epidermal growth factor receptor inhibitor gefitinib in non-small cell lung cancer cell lines: role of gefitinib-induced down regulation of thymidylate synthase. Mol Cancer Ther 7(3):599-606, 2008. (Pubitemid 351492458)