메뉴 건너뛰기




Volumn 20, Issue 7, 2011, Pages 1143-1152

Inhibition of p38 mitogen-activated protein kinase promotes ex vivo hematopoietic stem cell expansion

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOKINE RECEPTOR CXCR4; FLT3 LIGAND; MITOGEN ACTIVATED PROTEIN KINASE P38; STEM CELL FACTOR; THROMBOPOIETIN;

EID: 79959818068     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2010.0413     Document Type: Article
Times cited : (63)

References (37)
  • 1
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis JM and J Avruch. (2001). Mammalian mitogenactivated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807-869. (Pubitemid 32267078)
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 2
    • 69449088578 scopus 로고    scopus 로고
    • MAPK signaling pathways in the regulation of hematopoiesis
    • Geest CR and PJ Coffer. (2009). MAPK signaling pathways in the regulation of hematopoiesis. J Leukoc Biol 86:237-250.
    • (2009) J Leukoc Biol , vol.86 , pp. 237-250
    • Geest, C.R.1    Coffer, P.J.2
  • 3
    • 0142214646 scopus 로고    scopus 로고
    • Thrombopoietin stimulates Hoxb4 expression: An explanation for the favorable effects of TPO on hematopoietic stem cells
    • DOI 10.1182/blood-2003-03-0944
    • Kirito K, N Fox and K Kaushansky. (2003). Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells. Blood 102:3172-3178. (Pubitemid 37314753)
    • (2003) Blood , vol.102 , Issue.9 , pp. 3172-3178
    • Kirito, K.1    Fox, N.2    Kaushansky, K.3
  • 4
    • 0030788708 scopus 로고    scopus 로고
    • Activation of p38 MAP kinase pathway by erythropoietin and interleukin- 3
    • Nagata Y, T Moriguchi, E Nishida and K Todokoro. (1997). Activation of p38 MAP kinase pathway by erythropoietin and interleukin-3. Blood 90:929-934. (Pubitemid 27314124)
    • (1997) Blood , vol.90 , Issue.3 , pp. 929-934
    • Nagata, Y.1    Moriguchi, T.2    Nishida, E.3    Todokoro, K.4
  • 5
    • 0033548164 scopus 로고    scopus 로고
    • Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation
    • Rausch O and CJ Marshall. (1999). Cooperation of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways during granulocyte colony-stimulating factor-induced hemopoietic cell proliferation. J Biol Chem 274:4096-4105.
    • (1999) J Biol Chem , vol.274 , pp. 4096-4105
    • Rausch, O.1    Marshall, C.J.2
  • 7
    • 0037097528 scopus 로고    scopus 로고
    • Cutting edge: Activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia
    • Verma A, DK Deb, A Sassano, S Kambhampati, A Wickrema, S Uddin, M Mohindru, BK Van and LC Platanias. (2002). Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokineinduced hemopoietic suppression in aplastic anemia. J Immunol 168:5984-5988. (Pubitemid 34620009)
    • (2002) Journal of Immunology , vol.168 , Issue.12 , pp. 5984-5988
    • Verma, A.1    Deb, D.K.2    Sassano, A.3    Kambhampati, S.4    Wickrema, A.5    Uddin, S.6    Mohindru, M.7    Van Besien, K.8    Platanias, L.C.9
  • 8
    • 0037040869 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-β on normal hematopoiesis
    • DOI 10.1074/jbc.M106640200
    • Verma A, DK Deb, A Sassano, S Uddin, J Varga, A Wickrema and LC Platanias. (2002). Activation of the p38 mitogen- activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factorbeta on normal hematopoiesis. J Biol Chem 277:7726-7735. (Pubitemid 34968219)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.10 , pp. 7726-7735
    • Verma, A.1    Deb, D.K.2    Sassano, A.3    Uddin, S.4    Varga, J.5    Wickrema, A.6    Platanias, L.C.7
  • 9
    • 33947309693 scopus 로고    scopus 로고
    • p38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure
    • Zhou L, J Opalinska and A Verma. (2007). p38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure. Cell Cycle 6:534-537. (Pubitemid 46440424)
    • (2007) Cell Cycle , vol.6 , Issue.5 , pp. 534-537
    • Zhou, L.1    Opalinska, J.2    Verma, A.3
  • 10
    • 0034697904 scopus 로고    scopus 로고
    • Requirement for p38alpha in erythropoietin expression: A role for stress kinases in erythropoiesis
    • Tamura K, T Sudo, U Senftleben, AM Dadak, R Johnson and M Karin. (2000). Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102:221-231.
    • (2000) Cell , vol.102 , pp. 221-231
    • Tamura, K.1    Sudo, T.2    Senftleben, U.3    Dadak, A.M.4    Johnson, R.5    Karin, M.6
  • 16
    • 33845522237 scopus 로고    scopus 로고
    • Ex vivo expansion of umbilical cord blood stem cells for transplantation: Growing knowledge from the hematopoietic niche
    • DOI 10.1038/sj.bmt.1705538, PII 1705538
    • Hofmeister CC, J Zhang, KL Knight, P Le and PJ Stiff. (2007). Ex vivo expansion of umbilical cord blood stem cells for transplantation: growing knowledge from the hematopoietic niche. Bone Marrow Transplant 39:11-23. (Pubitemid 44921650)
    • (2007) Bone Marrow Transplantation , vol.39 , Issue.1 , pp. 11-23
    • Hofmeister, C.C.1    Zhang, J.2    Knight, K.L.3    Le, P.4    Stiff, P.J.5
  • 18
    • 0042809621 scopus 로고    scopus 로고
    • Regulation of hematopoietic stem cell selfrenewal
    • DOI 10.1210/rp.58.1.283
    • Reya T. (2003). Regulation of hematopoietic stem cell selfrenewal. Recent Prog Horm Res 58:283-295. (Pubitemid 37339314)
    • (2003) Recent Progress in Hormone Research , vol.58 , pp. 283-295
    • Reya, T.1
  • 19
    • 33644513357 scopus 로고    scopus 로고
    • Very low O2 concentration (0.1%) favors G0 return of dividing CD34 + cells
    • Hermitte F, P Brunet de la Grange, F Belloc, V Praloran and Z Ivanovic. (2006). Very low O2 concentration (0.1%) favors G0 return of dividing CD34 + cells. Stem Cells 24:65-73.
    • (2006) Stem Cells , vol.24 , pp. 65-73
    • Hermitte, F.1    De La G.P.Brunet2    Belloc, F.3    Praloran, V.4    Ivanovic, Z.5
  • 20
    • 0034518466 scopus 로고    scopus 로고
    • Primitive human HPCs are better maintained and expanded in vitro at 1 perent oxygen than at 20 percent
    • DOI 10.1046/j.1537-2995.2000.40121482.x
    • Ivanovic Z, SP Dello, F Trimoreau, JL Faucher and V Praloran. (2000). Primitive human HPCs are better maintained and expanded in vitro at 1 percent oxygen than at 20 percent. Transfusion 40:1482-1488. (Pubitemid 32049053)
    • (2000) Transfusion , vol.40 , Issue.12 , pp. 1482-1488
    • Ivanovic, Z.1    Sbarba, P.D.2    Trimoreau, F.3    Faucher, J.-L.4    Praloran, V.5
  • 22
    • 0036719870 scopus 로고    scopus 로고
    • The non-diaryl heterocycle classes of p38 MAP kinase inhibitors
    • Cirillo PF, C Pargellis and J Regan. (2002). The non-diaryl heterocycle classes of p38 MAP kinase inhibitors. Curr Top Med Chem 2:1021-1035.
    • (2002) Curr Top Med Chem , vol.2 , pp. 1021-1035
    • Cirillo, P.F.1    Pargellis, C.2    Regan, J.3
  • 23
    • 30144439380 scopus 로고    scopus 로고
    • Total body irradiation selectively induces murine hematopoietic stem cell senescence
    • DOI 10.1182/blood-2005-04-1418
    • Wang Y, BA Schulte, AC LaRue, M Ogawa and D Zhou. (2006). Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood 107:358-366. (Pubitemid 43053564)
    • (2006) Blood , vol.107 , Issue.1 , pp. 358-366
    • Wang, Y.1    Schulte, B.A.2    LaRue, A.C.3    Ogawa, M.4    Zhou, D.5
  • 24
    • 0024388891 scopus 로고
    • An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse
    • Ploemacher RE, JP van der Sluijs, JS Voerman and NH Brons. (1989). An in vitro limiting-dilution assay of longterm repopulating hematopoietic stem cells in the mouse. Blood 74:2755-2763. (Pubitemid 20007803)
    • (1989) Blood , vol.74 , Issue.8 , pp. 2755-2763
    • Ploemacher, R.E.1    Van Der Sluijs, J.P.2    Voerman, J.S.A.3    Brons, N.H.C.4
  • 25
    • 2342435563 scopus 로고    scopus 로고
    • Murine bone marrow cells cultured ex vivo in the presence of multiple cytokine combinations lose radioprotective and long-term engraftment potential
    • DOI 10.1089/154732804773099308
    • Von DA, G Alespeiti, L Ren and JW Adamson. (2004). Murine bone marrow cells cultured ex vivo in the presence of multiple cytokine combinations lose radioprotective and long-term engraftment potential. Stem Cells Dev 13:101-111. (Pubitemid 38560047)
    • (2004) Stem Cells and Development , vol.13 , Issue.1 , pp. 101-111
    • Von Drygalski, A.1    Alespeiti, G.2    Ren, L.3    Adamson, J.W.4
  • 26
  • 27
    • 34548153747 scopus 로고    scopus 로고
    • How stem cells age and why this makes us grow old
    • DOI 10.1038/nrm2241, PII NRM2241
    • Sharpless NE and RA DePinho. (2007). How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol 8:703-713. (Pubitemid 47312828)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 703-713
    • Sharpless, N.E.1    DePinho, R.A.2
  • 28
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • DOI 10.1016/S0092-8674(02)00697-9
    • Antonchuk J, G Sauvageau and RK Humphries. (2002). HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell 109:39-45. (Pubitemid 34327515)
    • (2002) Cell , vol.109 , Issue.1 , pp. 39-45
    • Antonchuk, J.1    Sauvageau, G.2    Humphries R.Keith3
  • 29
    • 36549058333 scopus 로고    scopus 로고
    • Chemokines in hematopoiesis
    • DOI 10.1097/MOH.0b013e3282f29012, PII 0006275220080100000009
    • Broxmeyer HE. (2008). Chemokines in hematopoiesis. Curr Opin Hematol 15:49-58. (Pubitemid 350191028)
    • (2008) Current Opinion in Hematology , vol.15 , Issue.1 , pp. 49-58
    • Broxmeyer, H.E.1
  • 30
    • 26244436798 scopus 로고    scopus 로고
    • Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion
    • DOI 10.1016/j.exphem.2005.05.018, PII S0301472X05002535
    • Madlambayan GJ, I Rogers, DC Kirouac, N Yamanaka, F Mazurier, M Doedens, RF Casper, JE Dick and PW Zandstra. (2005). Dynamic changes in cellular and microenvironmental composition can be controlled to elicit in vitro human hematopoietic stem cell expansion. Exp Hematol 33:1229-1239. (Pubitemid 41416972)
    • (2005) Experimental Hematology , vol.33 , Issue.10 , pp. 1229-1239
    • Madlambayan, G.J.1    Rogers, I.2    Kirouac, D.C.3    Yamanaka, N.4    Mazurier, F.5    Doedens, M.6    Casper, R.F.7    Dick, J.E.8    Zandstra, P.W.9
  • 31
    • 0027993402 scopus 로고
    • Growth acceleration and stem cell expansion in Dexter-type cultures by neutralization of TGF-β
    • Waegell WO, HR Higley, PW Kincade and JR Dasch. (1994). Growth acceleration and stem cell expansion in Dexter-type cultures by neutralization of TGF-beta. Exp Hematol 22:1051-1057. (Pubitemid 24314769)
    • (1994) Experimental Hematology , vol.22 , Issue.11 , pp. 1051-1057
    • Waegell, W.O.1    Higley, H.R.2    Kincade, P.W.3    Dasch, J.R.4
  • 32
    • 0345932931 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway
    • DOI 10.1046/j.1365-2443.2003.00620.x
    • Iwasa H, J Han and F Ishikawa. (2003). Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway. Genes Cells 8:131-144. (Pubitemid 36511698)
    • (2003) Genes to Cells , vol.8 , Issue.2 , pp. 131-144
    • Iwasa, H.1    Han, J.2    Ishikawa, F.3
  • 33
    • 66449084405 scopus 로고    scopus 로고
    • P38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms
    • Kwong J, L Hong, R Liao, Q Deng, J Han and P Sun. (2009). p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms. J Biol Chem 284:11237-11246.
    • (2009) J Biol Chem , vol.284 , pp. 11237-11246
    • Kwong, J.1    Hong, L.2    Liao, R.3    Deng, Q.4    Han, J.5    Sun, P.6
  • 37
    • 58549117478 scopus 로고    scopus 로고
    • Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4
    • Tang Y, J Chen and NS Young. (2009). Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4. Br J Haematol 144:603-612.
    • (2009) Br J Haematol , vol.144 , pp. 603-612
    • Tang, Y.1    Chen, J.2    Young, N.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.