Influence of freeze-drying process on porosity and kinetics release of collagen-doxycycline matrices

Proceedings of the 3rd International Conference on Advanced Materials and Systems, ICAMS 2010

Volumn , Issue , 2010, Pages 181-186

  Albu, Madalina Georgiana ^a   Ghica, Mihaela Violeta ^b   Ficai, Anton ^c   Titorencu, Irina ^a,d,e   Popa, Lacramioara ^b  

^a Section Collagen   (Romania)

^b CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c UNIVERSITY POLITEHNICA OF BUCHAREST   (Romania)

^d PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

^e INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

Author keywords

Collagen matrices; Freeze drying process; Kinetics release; Porosity

Indexed keywords

BONE TISSUE ENGINEERING; CELL POPULATIONS; COLLAGEN MATRICES; DIFFERENT PORE SIZES; DOXYCYCLINE; DRUG DIFFUSION; EXTRACELLULAR MATRICES; FREEZE-DRYING PROCESS; FREEZING RATE; FROZEN SAMPLE; GLUTARALDEHYDES; ICE CRYSTALS; ICE SUBLIMATION; IN-VITRO; INTERCONNECTED STRUCTURES; KINETICS MECHANISM; KINETICS RELEASE; MATRIX; OSTEOPROGENITOR CELLS; PORE SHAPE; POROUS STRUCTURES; RELEASE RATE; SANDWICH DEVICES;

ALDEHYDES; BIOCOMPATIBILITY; CELL CULTURE; CELL PROLIFERATION; DRUG DELIVERY; DRUG INTERACTIONS; DRYING; ENDOTHELIAL CELLS; KINETICS; LOW TEMPERATURE DRYING; MATHEMATICAL MODELS; PHASE TRANSITIONS; PORE SIZE; RESERVOIRS (WATER); SCAFFOLDS (BIOLOGY); SCANNING ELECTRON MICROSCOPY; TISSUE; WATER ABSORPTION;

COLLAGEN;

EID: 79959812706     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (7)

1. Albu, M.G. (2009), "Collagen Gels and Matrices with Different Hydration Degrees and Cvasisolid Structure for Biomedical Applications", Doctoral Thesis, University of Bucharest.
2. Berridge, V. and Tan, A.S. (1993), "Characterization of the Cellular Reduction of 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT): Subcellular Localization, Substrate Dependence, and Involvement of Mitochondrial Electron Transport in MTT Reduction", Archives of Biochemistry and Biophysics, 303, 474-82.
3. Ghica, M.V., Albu, M.G., Popa, L. et al. (2009), "Drug Delivery Systems Based on Collagen-Tannic Acid Matrices", Revue Roumaine de Chimie, 54(11-12), 1103-1110.
4. Mikhalovska, L.I., Gun'ko, V.M., Turov, V.V. et al. (2006), "Characterization of the Nanoporous Structure of Collagen-Glycosaminoglycan Hydrogels by Freezing-out of Bulk and Bound Water", Biomaterials, 27, 3599-3607.
5. O'Brien, F.J., Harley, B.A., Yanas, V.I. et al. (2004), "Influence of Freezing Rate on Pore Structure in Freeze-Dried Collagen-GAG Scaffolds", Biomaterials, 25, 1077-1086. (Pubitemid 37393297)
6. Sokolsky-Papkov, M., Agashi, K., Olaye, A. et al. (2007), "Polymer Carriers for Drug Delivery in Tissue Engineering", Advanced Drug Delivery Reviews, 59, 187-206. (Pubitemid 46887622)
7. Titorencu, I., Albu, M.G., Giurginca, M. et al. (2010), "In vitro Biocompatibility of Human Endothelial Cells with Collagen-Doxycycline Matrices ", Mollecular Crystals and Liquid Crystals, 522, 82-96.