Tan IIA inhibits COX-2-regulated VEGF expression in human colon cancer HCT-116 cells

World Chinese Journal of Digestology

Volumn 19, Issue 15, 2011, Pages 1561-1567

  Zhou, Li Hong ^a   Wang, Yan ^a   Fan, Zhong Ze ^a   Wu, Qiong ^a   Liu, Xuan ^a   Ci, Shu Jun ^a   Li, Q ^a  

^a Shanghai Putuo District Central Hospital   (China)

Author keywords

Colon cancer; Cyclooxygenase 2; Tanshinone iia; Vascular endothelial growth factor

Indexed keywords

COMPLEMENTARY DNA; CYCLOOXYGENASE 2; LUCIFERASE; MESSENGER RNA; NITROBLUE TETRAZOLIUM; TANSHINONE IIA; VASCULOTROPIN;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN HCT116; CLINICAL EVALUATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECOMBINANT PLASMID; REGULATORY MECHANISM; VECTOR CONTROL;

EID: 79959764779     PISSN: 10093079     EISSN: None     Source Type: Journal    
DOI: 10.11569/wcjd.v19.i15.1561     Document Type: Article

References (21)

1. Chinese source.
2. Beasley NJ, Prevo R, Banerji S, Leek RD, Moore J, van Trappen P, Cox G, Harris AL, Jackson DG. Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer. Cancer Res 2002; 62: 1315-1320
3. He Y, Rajantie I, Ilmonen M, Makinen T, Karkkainen MJ, Haiko P, Salven P, Alitalo K. Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis. Cancer Res 2004; 64: 3737-3740
4. Fujimura T, Ohta T, Oyama K, Miyashita T, Miwa K. Cyclooxygenase-2 (COX-2) in carcinogenesis and selective COX-2 inhibitors for chemoprevention in gastrointestinal cancers. J Gastrointest Cancer 2007; 38: 78-82
5. Adegboyega PA, Ololade O, Saada J, Mifflin R, Di Mari JF, Powell DW. Subepithelial myofibroblasts express cyclooxygenase-2 in colorectal tubular adenomas. Clin Cancer Res 2004; 10: 5870-5879
6. Koki AT, Khan NK, Woerner BM, Seibert K, Harmon JL, Dannenberg AJ, Soslow RA, Masferrer JL. Characterization of cyclooxygenase-2 (COX-2) during tumorigenesis in human epithelial cancers: evidence for potential clinical utility of COX-2 inhibitors in epithelial cancers. Prostaglandins Leukot Essent Fatty Acids 2002; 66: 13-18
7. Itatsu K, Sasaki M, Yamaguchi J, Ohira S, Ishikawa A, Ikeda H, Sato Y, Harada K, Zen Y, Sato H, Ohta T, Nagino M, Nimura Y, Nakanuma Y. Cyclooxygenase- 2 is involved in the up-regulation of matrix metalloproteinase-9 in cholangiocarcinoma induced by tumor necrosis factor-alpha. Am J Pathol 2009; 174: 829-841
8. Karahan N, Güney M, Baspinar S, Oral B, Kapucuoglu N, Mungan T. Expression of gelatinase (MMP-2 and MMP-9) and cyclooxygenase-2 (COX-2) in endometrial carcinoma. Eur J Gynaecol Oncol 2007; 28: 184-188
9. Dohadwala M, Yang SC, Luo J, Sharma S, Batra RK, Huang M, Lin Y, Goodglick L, Krysan K, Fishbein MC, Hong L, Lai C, Cameron RB, Gemmill RM, Drabkin HA, Dubinett SM. Cyclooxygenase-2- dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res 2006; 66: 5338-5345
10. Franchi A, Gallo O, Massi D, Baroni G, Santucci M. Tumor lymphangiogenesis in head and neck squamous cell carcinoma: a morphometric study with clinical correlations. Cancer 2004; 101: 973-978
11. Lazǎr D, Tǎban S, Ardeleanu C, Simionescu C, Sporea I, Cornianu M, Vernic C. Immunohistochemical expression of the cyclooxygenase-2 (COX-2) in gastric cancer. The correlations with the tumor angiogenesis and patients' survival. Rom J Morphol Embryol 2008; 49: 371-379
12. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983; 219: 983-985
13. Hotz HG, Hines OJ, Hotz B, Foitzik T, Buhr HJ, Reber HA. Evaluation of vascular endothelial growth factor blockade and matrix metalloproteinase inhi-bition as a combination therapy for experimental human pancreatic cancer. J Gastrointest Surg 2003; 7: 220-227; discussion 220-227
14. Chinese source.
15. Chinese source.
16. Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998; 93: 705-716
17. Hu MC, Hsu HJ, Guo IC, Chung BC. Function of Cyp11a1 in animal models. Mol Cell Endocrinol 2004; 215: 95-100
18. Chinese source.
19. Marques SM, Esteves da Silva JC. Firefly bioluminescence: a mechanistic approach of luciferase catalyzed reactions. IUBMB Life 2009; 61: 6-17
20. Chinese source.
21. Chinese source.