The S1103Y cardiac sodium channel variant is associated with implantable cardioverter-defibrillator events in blacks with heart failure and reduced ejection fraction

Circulation: Cardiovascular Genetics

Volumn 4, Issue 2, 2011, Pages 163-168

  Sun, Albert Y ^a,b   Koontz, Jason I ^a   Shah, Svati H ^a,c   Piccini, Jonathan P ^a,b   Nilsson Jr , Kent R ^a   Craig, Damian ^c   Haynes, Carol ^c   Gregory, Simon G ^c   Hranitzky, Patrick M ^a,d   Pitt, Geoffrey S ^a,b  

^a Divisions of Cardiovascular Diseases   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c Center for Human Genetics   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Death; Genetics; Heart failuR.E.; Ion channels; Race ethnicity; Sudden

Indexed keywords

SODIUM CHANNEL NAV1.5;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DEFIBRILLATION; DEFIBRILLATOR; FEMALE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HEART EJECTION FRACTION; HEART FAILURE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL;

AFRICAN AMERICANS; AGED; ALLELES; AMINO ACID SUBSTITUTION; ARRHYTHMIAS, CARDIAC; DEATH, SUDDEN, CARDIAC; DEFIBRILLATORS, IMPLANTABLE; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; SODIUM CHANNELS; STROKE VOLUME;

EID: 79959745470     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.110.958652     Document Type: Article

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