A porcine model of ischemic heart failure produced by intracoronary injection of ethyl alcohol

Heart and Vessels

Volumn 26, Issue 3, 2011, Pages 342-348

  Kim, Weon ^b   Jeong, Myung Ho ^a   Sim, Doo Sun ^a   Hong, Young Joon ^a   Song, Ho Cheon ^a   Park, Jong Tae ^a   Ahn, Young Keun ^a  

^a Chonnam National University Medical School   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

Animal model; Heart failure; Myocardial infarction; Pathology

Indexed keywords

ALCOHOL; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; TRIPHENYLTETRAZOLIUM;

ACUTE HEART INFARCTION; ANGIOCARDIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BALLOON CATHETER; CARDIOVERSION; CONTROLLED STUDY; CORONARY ARTERY CALCIFICATION; CORONARY ARTERY THROMBOSIS; DISEASE MODEL; DISEASE SEVERITY; EXPERIMENTAL PIG; HEART FAILURE; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE SIZE; HEART MUSCLE FIBROSIS; HEART MUSCLE PERFUSION; HEART VENTRICLE TACHYCARDIA; HEART VENTRICULOGRAPHY; HISTOPATHOLOGY; INJECTION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; M MODE ECHOCARDIOGRAPHY; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; REPRODUCIBILITY; SAFETY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SINUS RHYTHM; TRANSCATHETER INTRACORONARY INJECTION; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

ANIMALS; ANTERIOR WALL MYOCARDIAL INFARCTION; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; CORONARY VESSELS; DISEASE MODELS, ANIMAL; ELECTRIC COUNTERSHOCK; ETHANOL; FEMALE; HEART CATHETERIZATION; HEART FAILURE; INJECTIONS, INTRA-ARTERIAL; MYOCARDIAL PERFUSION IMAGING; MYOCARDIUM; STROKE VOLUME; SWINE; TACHYCARDIA, VENTRICULAR; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VENTRICULAR FUNCTION, LEFT;

EID: 79959742204     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-010-0022-3     Document Type: Article

References (25)

1. Pfeffer MA, Braunwald E (1990) Ventricular remodeling after myocardial infarction: experimental observations and clinical implications. Circulation 81:1161-1172 (Pubitemid 20119612)
2. The TIMI study group (1985) The thrombolysis in myocardial infarction (TIMI) trial: phase I findings. N Engl J Med 312:932-936
3. Ito H, Maruyama A, Iwakura K, Takiuchi S, Masuyama T, Hori M, Higashino Y, Fujii K, Minamino T (1996) Clinical implication of the "no reflow" phenomenon. Circulation 93:223-228
4. Korbling A, Estrov Z (2003) Medical progress: adult stem cells for tissue repair - a new therapeutic concept? Lancet 349:570-582
5. Strauer B, Kornowski R (2003) Stem cell therapy in perspective. Circulation 107:929-934 (Pubitemid 36258711)
6. Kamihata H, Matsubara H, Nishiue T, Fujiyama S, Tsutsumi Y, Ozono R, Masaki H, Mori Y, Iba O, Tateishi E, Kosaki A, Shintani S, Murohara T, Imaizumi T, Iwasaka T (2001) Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands, and cytokines. Circulation 104:1046-1052 (Pubitemid 32803883)
7. Ayisi K, Darup J, Krebber HJ, Rodewald G, Kuck KH (1989) Alcohol-induced coagulation necrosis in cardiac tissue: a new concept in the surgical management of recurrent ventricular arrhythmias. Thorac Cardiovasc Surg 37:76-79 (Pubitemid 19109701)
8. Weismuller P, Mayer U, Richter P, Heieck F, Kochs M, Hombach V (1991) Chemical ablation by subendocardial injection of ethanol via catheter-preliminary results in the pig heart. Eur Heart J 12:1234-1239
9. Haines DE, Whayne JG, DiMarco JP (1994) Intracoronary ethanol ablation in swine: effects of ethanol concentration on lesion formation and response to programmed ventricular stimulation. J Cardiovasc Electrophysiol 5:422-431 (Pubitemid 24151514)
10. Sahn DJ, DeMaria A, Kisslo J, Weyman A (1978) Recommendation regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 68:1072-1083 (Pubitemid 9091990)
11. Maxwell MP, Hears DJ, Yellon DM (1987) Species variation in the coronary collateral circulation during regional myocardial ischemia: a critical determinant of the rate of evolution and extent of myocardial infarction. Cardiovasc Res 21:737-746 (Pubitemid 17144243)
12. Bertho E, Gagnon G (1964) A comparative study in three dimensions of the blood supply of the normal interventricular septum in human, canine, bovine, porcine, ovine and equine heart. Dis Chest 46:251-262
13. Markovitz LJ, Savage EB, Ratcliffe MB, Bavaria JE, Kreiner G, Iozzo RV, Hargrove WC 3rd, Bogen DK, Edmunds LH Jr (1989) Large animal model of left ventricular aneurysm. Ann Thorac Surg 48:838-845 (Pubitemid 20013391)
14. Millner RW, Mann JM, Pearson I, Pepper JR (1991) Experimental model of left ventricular failure. Ann Thorac Surg 52:78-83
15. Terp K, Kim WY, Ulrich M, Frokiaer J, Baandrup U, Rehling M, Bagger JP, Hasenkam JM (1998) The hemodynamic impact of diffuse myocardial ischemic lesions: an animal experimental model based on intracoronary microembolization. Heart Vessels 13:132-141 (Pubitemid 29192207)
16. Harada K, Grossman W, Friedman M, Edelman ER, Prasad PV, Keighley CS, Manning WJ, Sellke FW, Simons M (1994) Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts. J Clin Invest 94:623-630 (Pubitemid 24250992)
17. Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TF, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Crystal RG, Rosengart TK (1998) Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J Thorac Cardiovasc Surg 115:168-177 (Pubitemid 28082163)
18. Sabbah HN, Stein PD, Kono T, Gheorghiade M, Levine TB, Jafri S, Hawkins ET, Goldstein S (1991) A canine model of chronic heart failure produced by multiple sequential coronary microembolizations. Am J Physiol 260:1379-1384
19. Li RK, Weisel RD, Mickle DA, Jia ZQ, Kim EJ, Sakai T, Tomita S, Schwartz L, Iwanochko M, Husain M, Cusimano RJ, Burns RJ, Yau TM (2000) Autologous porcine heart cell transplantation improved heart function after a myocardial infarction. J Thorac Cardiovasc Surg 119:62-68 (Pubitemid 30046314)
20. Sakaguchi G, Sakakibara Y, Tambara K, Lu F, Premaratne G, Nishimura K, Komeda M (2003) A pig model of chronic heart failure by intracoronary embolization with gelatin sponge. Ann Thorac Surg 75:1942-1947 (Pubitemid 36677244)
21. Maron BJ (2000) Role of alcohol septal ablation in treatment of obstructive hypertrophic cardiomyopathy. Lancet 355:425-426
22. Li ZQ, Cheng TO, Liu L, Jin YZ, Zhang M, Guan RM, Yuan L, Hu J, Zhang WW (2003) Experimental study of relationship between intracoronary alcohol injection and the size of resultant myocardial infarct. Int J Cardiol 91:93-96 (Pubitemid 37101104)
23. Veselka J, Zemánek D, Tomasov P, Duchonová R, Linhartová K (2009) Alcohol septal ablation for obstructive hypertrophic cardiomyopathy: ultra-low dose of alcohol (1 ml) is still effective. Heart Vessels 24:27-31
24. Duzenli MA, Ozdemir K, Aygul N, Soylu A, Aygul MU, Gök H (2009) Comparison of myocardial performance index obtained either by conventional echocardiography or tissue Doppler echocardiography in healthy subjects and patients with heart failure. Heart Vessels 24:8-15
25. Hua W (1992) The pathologic myocardial change caused by intracoronary ethyl alcohol injection and its mechanism. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 14:371-373