Anticarcinogenic effects of indigofera aspalathoides on 20-methylcholanthrene induced fibrosarcoma in rats

Research Journal of Medicinal Plant

Volumn 5, Issue 6, 2011, Pages 747-755

  Kumar, S S ^a   Rao, M R K ^a   Balasubramanian, M P ^b  

^a BHARATH UNIVERSITY   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Chemoprevention; Fibrosarcoma; Indigofera aspalathoides; Vitamin c; Vitamin e

Indexed keywords

3 METHYLCHOLANTHRENE; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ASCORBIC ACID; GLUTATHIONE; INDIGOFERA ASPALATHOIDES EXTRACT; PLANT EXTRACT; THIOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INCIDENCE; CANCER PREVENTION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; FIBROSARCOMA; INDIGOFERA; INDIGOFERA ASPALATHOIDES; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; RAT;

ANIMALIA; INDIGOFERA; RATTUS;

EID: 79959730302     PISSN: 18193455     EISSN: 21517924     Source Type: Journal    
DOI: 10.3923/rjmp.2011.747.755     Document Type: Article

References (35)

1. Allen, R.G., 1991. Oxygen-reactive species and antioxidant responses during development: The metabolic paradox by cellular differentiation. Proc. Soc. Exp. Biolol. Med., 196: 117-129.
2. Bakasso, S., A. Lamien-Meda, C.E. Lamien, M. Kiendrebeogo, J. Millogo, A.G. Ouedraogo and O.G. Nacoulma, 2008. Bolyphenol contents and antioxidant activities of five Indigofera species (Fabaceae) from Burkina Faso. Pak. J. Biol. Sci, 11: 1429-1435.
3. Barber, D.A. and S.R. Harris, 1994. Oxygen free radicals and antioxidants: A review. Am. Pharma., 34: 26-35.
4. Bhuvaneswari, R. and C. Balasundaram, 2006. Traditional Indian herbal extracts used in vitro against of pathogenic bacteria Aeromonas hydrophila. Israeli J. Aquae.-Bamidgeh, 58: 89-96.
5. Block, G. and M. Mankes, 1989. Ascorbic Acid in Cancer Prevention. In: Nutrition and Cancer Prevention, Moon, T. and E. Micozzims (Eds.). Marcel Dekker, New York, pp: 341-388.
6. Breimer, L.H., 1990. Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis. The role of DNAbase damage. Mol. Carcinog., 3: 188-197.
7. Ceutti, P.A., 1985. Pro-oxidant states and tumor promotion. Sciences, 227: 375-381.
8. Desai, I.D., 1984. Vitamin E analysis methods for animal tissue. Methods Enzymol.,105: 138-142.
9. Devasagayam, T.P. and U. Tarachand, 1987. Decreased lipid peroxidation in the rat kidney during gestation. Biochem. Biophys. Res. Commun., 145: 134-138.
10. Frei, B., L. England and B.N. Ames, 1989. Ascorbate is an outstanding antioxidant in human blood plasma. Proc. Natl. Acad. Sci. USA, 86: 6377-6381.
11. Greager, J.A, K. Reichard, J.P. Campana and T.K.D. Gupta, 1994. Fibrosarcoma of the head and neck. Am. J. Surg, 167: 437-439.
12. Grimble, R.F. and R.F. Huges, 1967. A dehydroascorbic acid reductase factor in guinea pig tissues. Cell. Mol. Life Sci., 23: 362-364.
13. HalHwell, B, 1990. How to characterize a biological antioxidant. Free Raical Res. Commun, 9: 1-32.
14. Heffner, D.K. and D.R. Gnepp, 1992. Sinonasal fibrosarcomas, malignant schwannomas and triton tumors: A clinicopathological study of 67 cases. Cancer, 70: 1089-1089.
15. Jones, M.W, H.J. Noris, E.S. Wargotz and S.W. Weiss, 1992. Fibrosarcoma malignant fibrous histiocytoma of the breast: A clinicopathological study of 32 cases. Am. J. Surg. Pathol, 16: 667-674.
16. Kirtikar, K.R. and B.D. Basu, 2000. Illustrated Indian Medicinal Plants. Sir Satguru's Publications, Delhi, pp: 2271.
17. Lai, M.G, J.A. Moscow, M.G. Alvarez, A.T. Fojo and S.E. Butes, 1991. Contribution of glutathione dependent enzymes in the reversal of adraimycin resistance to colon carcinoma cell lines. Int. Natl. J. Cancer, 49: 688-695.
18. Levine, M, 1986. New concepts in the biology and biochemistry of ascorbic acid. N. Engl. J. Med, 314: 892-902.
19. Liu, P.H, H.Y. Tsai, Y.W. Chung, Y.J. Wang and GF. Tseng, 2004. The proximity of the lesion to cell bodies determines the free radicals risks induced rats. Anat. Embryol, 207: 439-451.
20. Logrono, R, E.A. Filipowicz, F.J. Eyzagurire and R.N. Sawh, 1999. Diagnosis of primary sarcoma of the lung by fine needle aspiration and core biopsy. Arch. Pathol. Lab. Med, 123: 731-735.
21. Marnett, L.J, 2000. Oxyradicals and DNA damage. Carcinogen, 21: 361-370.
22. Moron, M.S., J.W. Depierre and B. Mannervik, 1979. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochem. Biophys. Acta, 582: 67-78.
23. Nagarajan, B. and S. Sankaran, 1973. A rapid method for the production of fibrosarcoma in rats and the effect of BCG administration. Ind. J. Cancer, 10: 83-84.
24. Omaye, S.T, J.D. Turnbull and H.E. Sauberlich, 1979. Selected methods for the determination of ascorbic acid in animals cells, tissues and fluids. Meth. Enzymol, 62: 3-11.
25. Oyashiki, T, N. Sakata and K. Matsui, 1994. Changes in SH reactivity of the protein in praline intestinal brush border membrane associated with lipid peroxidation. J. Biochem, 115: 224-229.
26. Packer, J.E, J.F. Slater and R.L. Willson, 1979. Direct observation of a free radical interaction between vitamin E and vitamin C. Nature, 278: 737-738.
27. Premalatha, B. and P. Sachidanandam, 1999. Semiecarpus anacardium L. nut extract administration induced the in vivo antioxidant defense system in aflatoxin Bl mediated hepatocellular carcinoma. J. Ethnopharmacol, 66: 131-139.
28. Rajkapoor, B, N. Murugesh, D. Chodon and D. Sakthisekaran, 2005. Chemoprevention of Nitosodiethylamine induced phenobarbitol promoted liver tumors in the rat by extract of Indigofera aspalathoides. Biol. Pharm. Bull, 28: 364-366.
29. Roussyn, I, K. Briviba, H. Masumoto and H. Sies, 1996. Selinium ontaining compounds protect DNA from single-strand breaks caused by peroxynitrate. Arch. Biochem. Biophys, 330: 216-218.
30. Sedlak, J. and R.H. Lindsay, 1968. Estimation of total protein bound and non-protein sulfhydryl groups in tissue with Ellman's reagent. Anal. Biochem, 5: 192-205.
31. Sen, C.K, 1995. Oxygen toxicity and antioxidants: State of the art. Indian J. Physiol. Pharmacol, 39: 177-196.
32. Sies, H, M.E. Murphy, P.D. Mascio and W. Stahl, 1992. Tocopherols, Carotmoids and the Glutathione. In: Lipid Soluble Antioxidants: Biochemistry and Clinical Application, Ong. A.S.H. andL. Packer (Eds.). Birkhauser Verlag, Switzerland, pp: 160-165.
33. Stout, A.P, 1948. Fibrosarcoma: The malignant tumor of fibrosis. Cancer, 1: 30-36.
34. Sun, Y, 1990. Free radicals, antioxidant enzymes and carcinogenesis. Free Radical Biol. Med, 8: 583-599.
35. Wiseman, H. and B. Halliwell, 1993. Carcinogenic antioxidants. Diethylstilbestrol, hexoestrol and 17-Alpha-etyloestradiol. FEBS Lett, 332: 159-163.