Circulating endothelial progenitor cells in patients with dysfunctional versus normally functioning congenitally bicuspid aortic valves

American Journal of Cardiology

Volumn 108, Issue 2, 2011, Pages 272-276

  Vaturi, Mordehay ^a,b   Perl, Leor ^a,b   Leshem Lev, Dorit ^b   Dadush, Oshrat ^b   Bental, Tamir ^a,b   Shapira, Yaron ^a,b   Yedidya, Idit ^a,b   Greenberg, Gabi ^a,b   Kornowski, Ran ^a,b   Sagie, Alexander ^a,b   Battler, Alexander ^a,b   Lev, Eli I ^a,b  

^a RABIN MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD34 ANTIGEN; VASCULOTROPIN RECEPTOR 2;

ADULT; AORTA ROOT; AORTA STENOSIS; AORTA VALVE REGURGITATION; ARTICLE; BICUSPID AORTIC VALVE; BLOOD ANALYSIS; CALCIFICATION; CARDIAC PATIENT; CELL FUNCTION; CELL MIGRATION; CLINICAL ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; FEMALE; FLOW CYTOMETRY; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE MASS; HEART VENTRICLE SEPTUM; HUMAN; HYPERTENSION; MALE; MITRAL VALVE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD; ANTIGENS, CD34; AORTIC VALVE; AORTIC VALVE INSUFFICIENCY; AORTIC VALVE STENOSIS; CASE-CONTROL STUDIES; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; FEMALE; FLOW CYTOMETRY; GLYCOPROTEINS; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PEPTIDES; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 79959716835     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2011.03.039     Document Type: Article

References (25)

1. H. Baumgartner Aortic stenosis: medical and surgical management Heart 91 2005 1483 1488 (Pubitemid 41531837)
2. E.R. Mohler III, F. Gannon, C. Reynolds, R. Zimmerman, M.G. Keane, and F.S. Kaplan Bone formation and inflammation in cardiac valves Circulation 103 2001 1522 1528 (Pubitemid 32226259)
3. D.E. Newby, S.J. Cowell, and N.A. Boon Emerging medical treatments for aortic stenosis: statins, angiotensin converting enzyme inhibitors, or both? Heart 92 2006 729 734 (Pubitemid 43799199)
4. S. Dimmeler, and A.M. Zeiher Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis? J Mol Med 82 2004 671 677 (Pubitemid 39468491)
5. J.E. Deanfield, J.P. Halcox, and T.J. Rabelink Endothelial function and dysfunction: testing and clinical relevance Circulation 115 2007 1285 1295 (Pubitemid 46594773)
6. S.A. Sorrentino, F.H. Bahlmann, C. Besler, M. Muller, S. Schulz, N. Kirchhoff, C. Doerries, T. Horvath, A. Limbourg, F. Limbourg, D. Fliser, H. Haller, H. Drexler, and U. Landmesser Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-[gamma] agonist rosiglitazone Circulation 116 2007 163 173 (Pubitemid 47057522)
7. T. Asahara, H. Masuda, T. Takahashi, C. Kalka, C. Pastore, M. Silver, M. Kearne, M. Magner, and J.M. Isner Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization Circ Res 85 1999 221 228 (Pubitemid 29377293)
8. U.M. Gehling, S. Ergn, U. Schumacher, C. Wagener, K. Pantel, M. Otte, G. Schuch, P. Schafhausen, T. Mende, N. Kilic, K. Kluge, B. Schfer, D.K. Hossfeld, and W. Fiedler In vitro differentiation of endothelial cells from AC133-positive progenitor cells Blood 95 2000 3106 3112 (Pubitemid 30321161)
9. M. Hristov, and C. Weber Endothelial progenitor cells: characterization, pathophysiology, and possible clinical relevance J Cell Mol Med 8 2004 498 508 (Pubitemid 44145482)
10. M. Peichev, A.J. Naiyer, D. Pereira, Z. Zhu, W.J. Lane, M. Williams, M.C. Oz, D.J. Hicklin, L. Witte, M.A. Moore, and S. Rafii Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors Blood 95 2000 952 958 (Pubitemid 30062717)
11. C. Urbich, and S. Dimmeler Endothelial progenitor cells: characterization and role in vascular biology Circ Res 95 2004 343 353 (Pubitemid 39100452)
12. D.H. Walter, K. Rittig, F.H. Bahlmann, R. Kirchmair, M. Silver, T. Murayama, H. Nishimura, D.W. Losordo, T. Asahara, and J.M. Isner Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells Circulation 105 2002 3017 3024 (Pubitemid 34693836)
13. N. Werner, J. Priller, U. Laufs, M. Endres, M. Bhm, U. Dirnagl, and G. Nickenig Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3- methylglutaryl coenzyme A reductase inhibition Arterioscler Thromb Vasc Biol 22 2002 1567 1572
14. E. Shantsila, T. Watson, and G.Y. Lip Endothelial progenitor cells in cardiovascular disorders J Am Coll Cardiol 49 2007 741 752
15. Y. Matsumoto, V. Adams, C. Walther, C. Kleinecke, P. Brugger, A. Linke, T. Walther, F.W. Mohr, and G. Schuler Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repair Eur Heart J 30 2009 346 355
16. J.M. Hill, G. Zalos, J.P. Halcox, W.H. Schenke, M.A. Waclawiw, A.A. Quyyumi, and T. Finkel Circulating endothelial progenitor cells, vascular function, and cardiovascular risk N Engl J Med 348 2003 593 600 (Pubitemid 36204953)
17. E.I. Lev, D. Leshem-Lev, A. Mager, H. Vaknin-Assa, N. Harel, Y. Zimra, T. Bental, G. Greenberg, D. Dvir, A. Solodky, A. Assali, A. Battler, and R. Kornowski Circulating endothelial progenitor cell levels and function in patients who experienced late coronary stent thrombosis Eur Heart J 31 2010 2625 2632
18. M. Vasa, S. Fichtlscherer, K. Adler, A. Aicher, H. Martin, A.M. Zeiher, and S. Dimmeler Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease Circulation 103 2001 2885 2890 (Pubitemid 32578123)
19. J.Z. Chen, J.H. Zhu, X.X. Wang, J.H. Zhu, X.D. Xie, J. Sun, Y.P. Shang, X.G. Guo, H.M. Dai, and S.J. Hu Effects of homocysteine on number and activity of endothelial progenitor cells from peripheral blood J Mol Cell Cardiol 36 2004 233 239 (Pubitemid 38202352)
20. M. Campbell The natural history of congenital aortic stenosis Br Heart J 30 1968 514 526
21. M. Campbell Calcific aortic stenosis and congenital bicuspid aortic valves Br Heart J 30 1969 606 616
22. N. Tzemos, J. Therrien, J. Yip, G. Thanassoulis, S. Tremblay, M.T. Jamorski, G.D. Webb, and S.C. Siu Outcomes in adults with bicuspid aortic valves JAMA 300 2008 1317 1325
23. H.I. Michelena, V.A. Desjardins, J.F. Avierinos, A. Russo, V.T. Nkomo, T.M. Sundt, P.A. Pellikka, A.J. Tajik, and M. Enriquez-Sarano Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community Circulation 117 2008 2776 2784 (Pubitemid 351770458)
24. A.M. Leone, M. Valgimigli, M.B. Giannico, V. Zaccone, M. Perfetti, D. D'Amario, A.G. Rebuzzi, and F. Crea From bone marrow to the arterial wall: the ongoing tale of endothelial progenitor cells Eur Heart J 30 2009 890 899
25. T. Imanishi, C. Moriwaki, T. Hano, and I. Nishio Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension J Hypertens 23 2005 1831 1837 (Pubitemid 41830423)