Sulfolipid accumulation in Mycobacterium tuberculosis disrupted in the mce2 operon

Journal of Microbiology

Volumn 49, Issue 3, 2011, Pages 441-447

  Marjanovic, Olivera ^a   Iavarone, Anthony T ^b   Riley, Lee W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

M. tuberculosis; mass spectrometry; mce operons; sulfolipid 1; thin layer chromatography

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; LIPID; MCE2 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; SULFOLIPIDS;

ARTICLE; BIOSYNTHESIS; CELL WALL; GENETICS; HUMAN; MASS SPECTROMETRY; METABOLISM; MICROBIOLOGY; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OPERON; THIN LAYER CHROMATOGRAPHY; TUBERCULOSIS;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL WALL; CHROMATOGRAPHY, THIN LAYER; HUMANS; LIPIDS; MASS SPECTROMETRY; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OPERON; TUBERCULOSIS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 79959704042     PISSN: 12258873     EISSN: 12258873     Source Type: Journal    
DOI: 10.1007/s12275-011-0435-4     Document Type: Article

References (34)

1. Belanger, A. E. and J. M. Inamine. 2000. Genetics of Cell Wall Biosynthesis, pp. 191-202. In G. F. Hartfull and W. R. J. Jacobs (eds.), Molecular Genetics of Mycobacteria. American Society of Microbiology, Washington, DC, USA.
2. Besra, G. S. and P. J. Brennan. 1997. The mycobacterial cell wall: biosynthesis of arabinogalactan and lipoarabinomannan. Biochem. Soc. Trans. 25, 845-850.
3. Brennan, P. J. and P. Draper. 1994. Ultrastructure of Mycobacterium tuberculosis, pp. 271-306. In B. R. Bloom (ed.), Tuberculosis: Pathogenesis, Protection and Control. ASM Press, Washington, DC, USA.
4. Casali, N. and L. W. Riley. 2007. A phylogenomic analysis of the Actinomycetales mce operons. BMC Genomics 8, 60.
5. Converse, S. E., J. D. Mougous, M. D. Leavell, J. A. Leary, C. R. Bertozzi, and J. S. Cox. 2003. MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc. Natl. Acad. Sci. USA 100, 6121-6126.
6. Daffe, M. and P. Draper. 1998. The envelope layers of mycobacteria with reference to their pathogenicity. Adv. Microb. Physiol. 39, 131-203.
7. Dassa, E. and P. Bouige. 2001. The ABC of ABCS: a phylogenetic and functional classification of ABC systems in living organisms. Res. Microbiol. 152, 211-229.
8. Dobson, G., D. E. Minnikin, S. M. Minnikin, J. H. Parlett, M. Goodfellow, M. Ridell, and M. Magnusson. 1985. Systematic analysis of complex mycobacterial lipids, pp. 237-265. In M. Goodfellow and D. E. Minnikin (eds.), Chemical Methods in Bacterial Systematics. Academic Press, London, UK.
9. Dunphy, K. Y., R. H. Senaratne, M. Masuzawa, L. V. Kendall, and L. W. Riley. 2010. Attenuation of Mycobacterium tuberculosis functionally disrupted in a fatty acyl-coenzyme A synthetase gene fadD5. J. Infect. Dis. 201, 1232-1239.
10. Fratti, R. A., J. Chua, I. Vergne, and V. Deretic. 2003. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc. Natl. Acad. Sci. USA 100, 5437-5442.
11. Gangadharam, P. R., M. L. Cohn, and G. Middlebrook. 1963. Infectivity, pathogenicity and sulpholipid fraction of some Indian and British strains of tubercle Bacilli. Tubercle 44, 452-455.
12. Geisel, R. E., K. Sakamoto, D. G. Russell, and E. R. Rhoades. 2005. In vivo activity of released cell wall lipids of Mycobacterium bovis bacillus Calmette-Guerin is due principally to trehalose mycolates. J. Immunol. 174, 5007-5015.
13. Houben, E. N., L. Nguyen, and J. Pieters. 2006. Interaction of pathogenic mycobacteria with the host immune system. Curr. Opin. Microbiol. 9, 76-85.
14. Kumar, P., M. W. Schelle, M. Jain, F. L. Lin, C. J. Petzold, M. D. Leavell, J. A. Leary, J. S. Cox, and C. R. Bertozzi. 2007. PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc. Natl. Acad. Sci. USA 104, 11221-11226.
15. Lin, H. H., D. E. Faunce, M. Stacey, A. Terajewicz, T. Nakamura, J. Zhang-Hoover, M. Kerley, M. L. Mucenski, S. Gordon, and J. Stein-Streilein. 2005. The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance. J. Exp. Med. 201, 1615-1625.
16. Livak, K. J. and T. D. Schmittgen. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408.
17. Marjanovic, O., T. Miyata, A. Goodridge, L. V. Kendall, and L. W. Riley. 2010. Mce2 operon mutant strain of Mycobacterium tuberculosis is attenuated in C57BL/6 mice. Tuberculosis 90, 50-56.
18. Marshall, A. G., C. L. Hendrickson, and G. S. Jackson. 1998. Mass spectrom. Review 17, 1-35.
19. Middlebrook, G., C. M. Coleman, and W. B. Schaefer. 1959. Sulfolipid from virulent tubercle Bacilli. Proc. Natl. Acad. Sci. USA 45, 1801-1804.
20. Minnikin, D. E. 1982. Lipids: complex lipids, their chemistry, biosynthesis and roles, pp. 95-184. In C. Ratledge and J. Stanford(eds.), The Biology of Mycobacteria. Academic Press, Ltd., London, UK.
21. Okamoto, Y., Y. Fujita, T. Naka, M. Hirai, I. Tomiyasu, and I. Yano. 2006. Mycobacterial sulfolipid shows a virulence by inhibiting cord factor induced granuloma formation and TNF-alpha release. Microb. Pathog. 40, 245-253.
22. Pandey, A. K. and C. M. Sassetti. 2008. Mycobacterial persistence requires the utilization of host cholesterol. Proc. Natl. Acad. Sci. USA 105, 4376-4380.
23. Parish, T. and N. G. Stoker. 2000. Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement. Microbiology 146, 1969-1975.
24. Rao, V., N. Fujiwara, S. A. Porcelli, and M. S. Glickman. 2005. Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. J. Exp. Med. 201, 535-543.
25. Reed, M. B., P. Domenech, C. Manca, H. Su, A. K. Barczak, B. N. Kreiswirth, G. Kaplan, and C. E. Barry, 3rd. 2004. A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response. Nature 431, 84-87.
26. Rousseau, C., O. C. Turner, E. Rush, Y. Bordat, T. D. Sirakova, P. E. Kolattukudy, S. Ritter, I. M. Orme, B. Gicquel, and M. Jackson. 2003. Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigs. Infect. Immun. 71, 4684-4690.
27. Santangelo Mde, L., F. Blanco, E. Campos, M. Soria, M. V. Bianco, L. Klepp, A. Alito, O. Zabal, A. Cataldi, and F. Bigi. 2009. Mce2R from Mycobacterium tuberculosis represses the expression of the mce2 operon. Tuberculosis 89, 22-28.
28. Senaratne, R. H., B. Sidders, P. Sequeira, G. Saunders, K. Dunphy, O. Marjanovic, J. R. Reader, and et al. 2008. Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice. J. Med. Microbiol. 57, 164-170.
29. Shimono, N., L. Morici, N. Casali, S. Cantrell, B. Sidders, S. Ehrt, and L. W. Riley. 2003. Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon. Proc. Natl. Acad. Sci. USA 100, 15918-15923.
30. Stacey, M., G. W. Chang, J. Q. Davies, M. J. Kwakkenbos, R. D. Sanderson, J. Hamann, S. Gordon, and H. H. Lin. 2003. The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans. Blood 102, 2916-2924.
31. Vergne, I., J. Chua, S. B. Singh, and V. Deretic. 2004. Cell biology of Mycobacterium tuberculosis phagosome. Annu. Rev. Cell. Dev. Biol. 20, 367-394.
32. Zhang, L., D. English, and B. R. Andersen. 1991. Activation of human neutrophils by Mycobacterium tuberculosis-derived sulfolipid-1. J. Immunol. 146, 2730-2736.
33. Zhang, L., J. C. Gay, D. English, and B. R. Andersen. 1994. Neutrophil priming mechanisms of sulfolipid-I and N-formyl-methionyl-leucyl-phenylalanine. J. Biomed. Sci. 1, 253-262.
34. Zhang, L., M. B. Goren, T. J. Holzer, and B. R. Andersen. 1988. Effect of Mycobacterium tuberculosis-derived sulfolipid I on human phagocytic cells. Infect. Immun. 56, 2876-2883.