Cell-cycle blockage associated with increased apoptotic cells in the thymus of chickens fed on diets high in fluorine

Human and Experimental Toxicology

Volumn 30, Issue 7, 2011, Pages 685-692

  Chen, Tao ^a,b   Cui, Hengmin ^a   Cui, Yun ^a   Bai, Caimin ^a   Gong, Tao ^a   Peng, Xi ^a  

^a SICHUAN AGRICULTURAL UNIVERSITY   (China)

^b WestChina Frontier PharmaTech/GLP Center   (China)

Author keywords

apoptosis; cell cycle blockage; flow cytometry; fluoride; thymus

Indexed keywords

FLUORINE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHICKEN; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; GROWTH RATE; HISTOPATHOLOGY; IMMUNE SYSTEM; IMMUNOTOXICITY; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE; THYMUS;

ADMINISTRATION, ORAL; ANIMAL FEED; ANIMALS; APOPTOSIS; CELL PROLIFERATION; CHICKENS; DNA; FLOW CYTOMETRY; FLUORINE COMPOUNDS; GROWTH; INTERPHASE; PLOIDIES; THYMUS GLAND;

AVES; GALLUS GALLUS;

EID: 79959701809     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327110379022     Document Type: Article

References (19)

1. Zhou B., Wang H., Wang J., Zhang J., Yan X., and Wang J. Effects of malnutrition and supplemented nutrition on nonspecific immune function changes induced by fluoride in rabbits. Fluoride 2007 ; 40: 169-177. (Pubitemid 47612345)
2. Matsui H., Morimoto M., Horimoto K., and Nishimura Y. Some characteristics of fluoride-induced cell death in rat thymocytes: cytotoxicity of sodium fluoride. Toxicol In Vitro 2007 ; 21: 1113-1120. (Pubitemid 47238241)
3. Gessner BD, Beller M., Middaugh JP, and Whitford GM Acute fluoride poisoning from a public water system. N Engl J Med 1994 ; 330: 95-99.
4. Takase I., Kono K., Tamura A., Nishio H., Dote T., and Suzuki K. Fatality due to acute fluoride poisoning in the workplace. Leg Med 2004 ; 6: 197-200. (Pubitemid 38844694)
5. Liu G., Chai C., and Cui L. Fluoride causing abnormally elevated serum nitric oxide levels in chicks. Environ Toxicol Pharmacol 2003 ; 13: 199-204. (Pubitemid 36369727)
6. Wang JD, Guo YH, Liang ZX, and Hao JH Amino acid composition and histopathology of goat teeth in an industrial fluoride polluted area. Fluoride 2003 ; 36: 177-184.
7. Shanthakumari D., Srinivalasalu S., and Subramanian S. Effect of fluoride intoxication on lipid peroxidation and antioxidant status in experimental rats. Toxicology 2004 ; 204: 219-228. (Pubitemid 39244082)
8. Pushpalatha T., Srinivas M., and Reddy PS Exposure to high fluoride concentration in drinking water will affect spermatogenesis and steroidogenesis in male albino rats. Biometals 2005 ; 18: 207-212. (Pubitemid 40685243)
9. Cinar A., Selcuk M. Effects of chronic fluorosis on thyroxine, triiodothyronine, and proteinbound iodine in cows. Fluoride 2005 ; 38: 65-68. (Pubitemid 40477879)
10. Suska M., Janiak M. Relationship between cellular adenine nucleotide concentrations in erythrocytes and serum fluoride levels in two breeds of sheep. Fluoride 2006 ; 39: 60-64.
11. Chen T., Gong T., Bai C., Peng X., and Cui H. Effect of dietary high fluorine on the morphologic structure, and cell cycle and apoptosis of bursa of fabricius in broilers. Acta Veterinaria et Zootechnica Sinica 2009 ; 40: 1235-1243.
12. Chen T., Cui Y., Gong T., Bai C., Peng X., and Cui H. Inhibition of splenocyte proliferation and spleen growth in young chickens fed high fluoride diets. Fluoride 2009 ; 42: 203-209.
13. Al-Hiyasat AS, Elbetieha AM, and Darmani H. Reproductive toxic effects of ingestion of sodium fluoride in female rats. Fluoride 2000 ; 33: 79-84.
14. Jeng JH, Hsieh CC, Lan WH, Chang MC, Lin SK, Hahn LJ, et al. Cytotoxicity of sodium fluoride on human oral mucosal fibroblasts and its mechanisms. Cell Biol Toxicol 1998 ; 14: 383-389. (Pubitemid 29008699)
15. Chen PZ, Sun HY, Yun ZJ, Gao HX, Ma AH, Wang YT, et al. Effect of fluoride on morphology and function of in vitro rat thymic epithelial cells and thymocytes. Chin J Epidemiol. 2005 ; 24: 21-24.
16. King KL, Cidlowski JA Cell cycle and apoptosis: common pathways to life and death. J Cell Biochem 2004 ; 58: 175-180.
17. Zhang X., Li J., Xu Z., and Wang M. Effects of fluoride on pancreatic digestive enzyme activities and ultrastructure in young pigs. Fluoride 2005 ; 38: 215-219. (Pubitemid 41225123)
18. Shivarajashankara YM, Shivashankara AR, Rao SH, and Bhat PG Oxidative stress in children with endemic skeletal fluorosis. Fluoride 2001 ; 34: 103-107. (Pubitemid 32802409)
19. Matsuzawa A., Nishitoh H., Tobiume K., Takeda K., and Ichijo H. Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid Red Sig 2002 ; 4: 415-425. (Pubitemid 34753381)