The death of ouabain-treated renal epithelial C11-MDCK cells is not mediated by swelling-induced plasma membrane rupture

Journal of Membrane Biology

Volumn 241, Issue 3, 2011, Pages 145-154

  Platonova, Alexandra ^a,b   Koltsova, Svetlana ^a,c   Maksimov, Georgy V ^b   Grygorczyk, Ryszard ^a   Orlov, Sergei N ^a,b,c  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

Author keywords

Cell death; Cell volume; Na+,K+ ATPase; Ouabain; Plasma membrane integrity; Renal epithelium; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATASE; LACTATE DEHYDROGENASE; OUABAIN; POTASSIUM; SODIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL SURVIVAL; CELL SWELLING; CELL VOLUME; CHROMATIN; EPITHELIUM CELL; KIDNEY EPITHELIUM; MEMBRANE RUPTURE; NONHUMAN; PLASMA MEMBRANE RUPTURE; RAT; SMOOTH MUSCLE FIBER;

ANIMALS; CELL ADHESION; CELL DEATH; CELL LINE; CELL MEMBRANE; CELL SIZE; CELL SURVIVAL; CHROMATIN; DOGS; EPITHELIAL CELLS; ION TRANSPORT; KIDNEY; L-LACTATE DEHYDROGENASE; MUSCLE, SMOOTH, VASCULAR; OSMOSIS; OSMOTIC PRESSURE; OUABAIN; POTASSIUM; RATS; RUBIDIUM; SODIUM ISOTOPES; SODIUM RADIOISOTOPES; SODIUM-POTASSIUM-EXCHANGING ATPASE;

RATTUS; STROPHANTHUS GRATUS;

EID: 79959699281     PISSN: 00222631     EISSN: 14321424     Source Type: Journal    
DOI: 10.1007/s00232-011-9371-9     Document Type: Article

References (62)

1. i-independent signaling in C7-MDCK cells. J Biol Chem 280:832-839
2. i-independent death signaling triggered by cardiotonic steroids. Pathophysiology 12:125-135
3. Akimova OA, Mongin AA, Hamet P, Orlov SN (2006a) The rapid decline of MTT reduction is not a marker of death signaling in ouabain-treated cells. Cell Mol Biol 52(8):71-77 (Pubitemid 46799708)
4. Akimova OA, Pchejetski D, Hamet P, Orlov SN (2006b) Modest intracellular acidification suppresses death signaling in ouabain-treated cells. Pflugers Arch 451:569-578 (Pubitemid 41789797)
5. Akimova OA, Poirier M, Kotelevtsev SV, Hamet P, Orlov SN (2008) The death of ouabain-treated renal epithelial cells: evidence against anoikis occurrence. Apoptosis 13:670-680
6. +-independent signaling. Apoptosis 14:1266-1273
7. i-independent mechanism. Apoptosis 15:55-62
8. Alam A, Cohen LY, Aouad S, Sékaly R-P (1990) Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J Exp Med 190:1879-1890
9. Alvarez-Leefmans FJ, Gamino SM, Reuss L (1992) Cell volume changes upon sodium pump inhibition in Helix aspersa neurones. J Physiol 458:603-619 (Pubitemid 23024612)
10. Andersen LK, Contera SA, Justesen J et al (2005) Cell volume increase in murine MC3T3-E1 pre-osteoblasts attaching onto biocompatible tantalum observed by magnetic AC mode atomic force microscopy. Eur Cell Mater 10:61-68
11. Aperia A (2007) New roles for an old Na, K-ATPase emerges as an interesting drug target. J Intern Med 261:44-52
12. Armstrong CM (2003) The Na/K pump, Cl ion, and osmotic stabilization of cells. Proc Natl Acad Sci USA 100:6257-6262
13. Bolivar JJ, Lazaro A, Fernandez S et al (1987) Rescue of a wild-type MDCK cell by a ouabain-resistant mutant. Am J Physiol Cell Physiol 253:C151-C161
14. Boudreault F, Grygorczyk R (2004) Evaluation of rapid volume changes of substrate-adherent cells by conventional microscopy 3D imaging. J Microsc 215:302-312 (Pubitemid 39233718)
15. Bourcier N, Grygorczyk R, Gekle M, Berthiaume Y, Orlov SN (2002) Purinergic-induced ion current in monolayers of C7-MDCK cells: role of basolateral and apical ion transporters. J Membr Biol 186:131-143 (Pubitemid 34442070)
16. Carini R, Autelli R, Bellomo G, Dianzani MU, Albano E (1995) Sodium-mediated cell swelling is associated with irreversible damage in isolated hepatocytes exposed to hypoxia or mitochondrial toxins. Biochem Biophys Res Commun 206:180-185
17. Carini R, Autelli R, Bellomo G, Albano E (1999) Alteration of cell volume regulation in the development of hepatocyte necrosis. Exp Cell Res 248:280-293 (Pubitemid 29393950)
18. Columbano A (1995) Cell death: current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo. J Cell Biochem 58:181-190
19. Contreras RG, Lazaro A, Mujica A et al (1995) Ouabain resistance of the epithelial cell line (Ma104) is not due to lack of affinity of its pumps for the drug. J Membr Biol 145:295-300
20. +-ATPase and cell attachment. J Cell Sci 112:4223-4232
21. +-ATPase relaxes cell attachment and sends a specific signal (NACos) to the nucleus. J Membr Biol 198: 147-158
22. Davis A, Hogarth K, Fernandes D et al (2003) Functional significance of protein kinase A (PKA) activation by endothelin-1 and ATP: negative regulation of SRF-dependent gene expression by PKA. Cell Signal 15:597-604
23. Dierkes PW, Wüstern HJ, Klees G, Müller A, Horchstrate P (2006) Ionic mechanism of ouabain-induced swelling of leech Retzuis neurons. Pflugers Arch 452:25-35
24. Dong X, Saikumar P, Weinberg JM, Venkatachalam MA (1997) Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Am J Pathol 151:1205-1213
25. Drewnowska K, Baumgarten CV (1991) Regulation of cellular volume in rabbit ventricular myocytes: bumetanide, chlorothiazide, and ouabain. Am J Physiol Cell Physiol 260:C122-C131
26. Duvall E, Wyllie AH (1986) Death and the cell. Immunol Today 7:115-119 (Pubitemid 17022305)
27. Falciola J, Volet B, Anner RM, Moosmayer M, Lacotte D, Anner BM (1994) Role of cell membrane Na, K-ATPase for survival of human lymphocytes in vivo. Biosci Rep 14:189-204
28. Fels J, Orlov SN, Grygorczyk R (2009) The hydrogel nature of mammalian cytoplasm contributes to osmosensing and extracellular pH sensing. Biophys J 96:4276-4285
29. Gekle M, Wunsch S, Oberleithner H, Silbernagl S (1994) Characterization of two MDCK-cell subtypes as a model system to study principal cell and intercalated cell properties. Pflugers Arch 428:157-162 (Pubitemid 24238860)
30. Granitzer M, Mountian I, De Smet P, Van Driessche W (1994) Effect of ouabain on membrane conductances and volume in A6 cells. Renal Physiol Biochem 17:223-231 (Pubitemid 24245248)
31. Groulx N, Boudreault F, Orlov SN, Grygorczyk R (2006) Membrane reserves and hypotonic cell swelling. J Membr Biol 214:43-56 (Pubitemid 47036676)
32. Hamann S, Kiilgaard JF, Litman T, Alvarez-Leefmans FJ, Winther BR, Zeuthen T (2002) Measurement of cell volume changes by fluorescence self-quenching. J Fluoresc 12:139-145
33. Heiden MGV, Chandel NS, Williamson EK, Schumacker PT, Thompson CB (1997) Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91:627-637 (Pubitemid 27513654)
34. Hoffmann EK, Lambert IH, Pedersen SF (2009) Physiology of cell volume regulation in vertebrates. Physiol Rev 89:193-277
35. Kimelberg HK, Ransom BR (1986) Physiological and pathophysiological aspects of astrocytic swelling. Astrocytes 3:129-166
36. Kroemer G, El-Diery WS, Golstein P et al (2005) Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 12:1463-1467 (Pubitemid 41553979)
37. Lang F, Busch G, Ritter M et al (1998) Functional significance of cell volume regulatory mechanisms. Physiol Rev 78:247-306 (Pubitemid 28070981)
38. Ledbetter ML, Young GJ, Wright ER (1986) Cooperation between epithelial cells demonstrated by potassium transfer. Am J Physiol Cell Physiol 250:C306-C313
39. Lingrel JB, Williams MT, Vorhees CV, Moseley AE (2007) Na, K-ATPase and the role of a isoforms in behaviour. J Bioenerg Bioeng 39:385-389
40. Macknight ADC, Leaf A (1977) Regulation of cellular volume. Physiol Rev 57:510-573 (Pubitemid 8154768)
41. Mongin AA, Orlov SN (2001) Mechanisms of cell volume regulation and possible nature of the cell volume sensor. Pathophysiology 8:77-88 (Pubitemid 33108983)
42. Nobel CSI, Aronson JK, van den Dobbelsteen DJ, Slater AFG (2000) Inhibition of Na+, K+-ATPase may be one mechanism contributing to potassium efflux and cell shrinkage in CD95-induced apoptosis. Apoptosis 5:153-163 (Pubitemid 30399389)
43. Okada Y, Maeno E, Shimizu T, Dezaki K, Wang J, Morishima S (2001) Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J Physiol 532: 3-16 (Pubitemid 32303268)
44. + ratio blocks apoptosis in vascular smooth muscle at a site upstream of caspase-3. J Biol Chem 274:16545-16552
45. i ratio: possible implication in vascular remodeling. J Hypertens 19:1559-1565
46. i. Pflugers Arch 448:335-345
47. Panayiotidis MI, Franco R, Bortner CD, Cidlowski JA (2010) Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis. Apoptosis 15: 834-849
48. i ratio. Biochem Biophys Res Commun 301:735-744
49. Reuss L (1985) Changes in cell volume measured with an electrophysiological technique. Proc Natl Acad Sci USA 82:6014-6018
50. Russo MA, Morgante E, Mariani MF, Yeh HI, Farber JL, van Rossum GD (1994) Effects of ouabain and chloride-free medium on isosmotic volume control and ultrastructure of hepatocytes in primary culture. Eur J Cell Biol 64:229-242 (Pubitemid 24258183)
51. Scheiner-Bobis G (2002) The sodium pump. Its molecular properties and mechanism of ion transport. Eur J Biochem 269:2424-2433
52. Schoner W, Scheiner-Bobis G (2007) Endogenous and exogenous cardiac glycosides: their role in hypertension, salt metabolism, and cell growth. Am J Physiol Cell Physiol 293:C509-C536 (Pubitemid 47235171)
53. Shimizu S, Eguchi Y, Kamiike W et al (1996) Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transduction. Oncogene 12:2045-2050 (Pubitemid 26168413)
54. Smith TW, Rasmusson RL, Lobaugh LA, Lieberman M (1993) Na+/K+ pump inhibition induces cell shrinkage in cultured chick cardiac myocytes. Basic Res Cardiol 88:411-420 (Pubitemid 24056128)
55. Solenov E, Altamirano J, Huerto L, Alvarez-Leefmans FJ (2004) Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol 286: C426-C432 (Pubitemid 38146367)
56. + loss. Am J Physiol Renal Fluid Electrolyte Physiol 258:F732-F740
57. + pump as revealed by experiments and simulation. J Gen Physiol 128:495-507
58. Vrbka L, Vondrasek J, Jagoda-Cwiklik B, Vasha R, Jungwirth P (2006) Quantification and rationalization of the higher affinity of sodium over potassium to protein surfaces. Proc Natl Acad Sci USA 103:15440-15444 (Pubitemid 44625610)
59. Warny M, Kelly CP (1999) Monocytic cell necrosis is mediated by potassium depletion and caspase-like proteases. Am J Physiol Cell Physiol 276:C717-C724 (Pubitemid 29157389)
60. Wyllie AH (1981) Cell death: a new classification separating apoptosis from necrosis. In: Bowen ID, Lockshin RA (eds) Cell death in biology and pathology. Chapman and Hall, London, pp 9-34
61. Xie Z (2003) Molecular mechanisms of Na/K-ATPase-mediated signal transduction. Ann N Y Acad Sci 986:497-503
62. Zhou QS, Zhao J, Stout JG, Luhm RA, Wiedmer PJ (1997) Molecular cloning of human plasma membrane phospholipid scramblase a protein mediating transbilayer movement of plasma membrane phospholipids. J Biol Chem 272:18240-18244