The opportunistic yeast pathogen Trichosporon asahii colonizes the skin of healthy individuals: Analysis of 380 healthy individuals by age and gender using a nested polymerase chain reaction assay

Microbiology and Immunology

Volumn 55, Issue 7, 2011, Pages 483-488

  Zhang, Enshi ^a,b   Sugita, Takashi ^a   Tsuboi, Ryoji ^b   Yamazaki, Takashi ^d   Makimura, Koichi ^c  

^a MEIJI PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

^c TEIKYO UNIVERSITY   (Japan)

^d JAPAN AEROSPACE EXPLORATION AGENCY   (Japan)

Author keywords

Microbiota; Skin; Trichosporon asahii

Indexed keywords

FUNGAL DNA; FUNGAL RNA; RIBOSOME RNA;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BLOOD ANALYSIS; CHILD; CONTROLLED STUDY; FEMALE; FUNGAL COLONIZATION; FUNGAL DETECTION; FUNGUS ISOLATION; GENOTYPE; HUMAN; INFANT; JAPANESE; MAJOR CLINICAL STUDY; MALE; OPPORTUNISTIC INFECTION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SCHOOL CHILD; SEX DIFFERENCE; SKIN; SKIN FLORA; SKIN INFECTION; TRICHOSPORON ASAHII; TRICHOSPORONOSIS; URINALYSIS;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CARRIER STATE; CHILD; CHILD, PRESCHOOL; DNA, FUNGAL; DNA, RIBOSOMAL SPACER; FEMALE; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; JAPAN; MALE; MIDDLE AGED; MYCOLOGICAL TYPING TECHNIQUES; POLYMERASE CHAIN REACTION; PREVALENCE; SEX FACTORS; SKIN; TRICHOSPORON; YOUNG ADULT;

TRICHOSPORON ASAHII;

EID: 79959695755     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2011.00341.x     Document Type: Article

References (36)

1. Sugita T. (1890) Trichosporon Behrend. In: Kurtzman C.P., Fell J.W., Boekhout T. eds. The Yeast: a Taxonomic Study, 5th edn, in press. Amsterdam, The Netherlands Elsevier.
2. Schwartz R.A. (2004) Superficial fungal infections. Lancet 364: 1173-82.
3. Guého E., Improvisi L., de Hoog G.S., Dupont B. (1994) Trichosporon on humans: a practical account. Mycoses 37: 3-10.
4. Tokimatsu I., Karashima R., Yamagata E., Yamakami Y., Nagai H., Kadota J., Nasu M. (2003) Pathogenesis of Trichosporon asahii and strategies for infectious control of disseminated trichosporonosis. Nippon Ishinkin Gakkai Zasshi 44: 181-6.
5. Walsh T.J., Groll A., Hiemenz J., Fleming R., Roilides E., Anaissie E. (2004) Infections due to emerging and uncommon medically important fungal pathogens. Clin Microbiol Infect 10: 48-66.
6. Hoy J., Hsu K.C., Rolston K., Hopfer R.L., Luna M., Bodey G.P. (1986) Trichosporon beigelii infection: a review. Rev Infect Dis 8: 959-67.
7. Chagas-Neto T.C., Chaves G.M., Melo A.S., Colombo A.L. (2009) Bloodstream infections due to Trichosporon spp.: species distribution, Trichosporon asahii genotypes determined on the basis of ribosomal DNA intergenic spacer 1 sequencing, and antifungal susceptibility testing. J Clin Microbiol 47: 1074-81.
8. Kalkanci A., Sugita T., Arikan S., Yucesoy M., Ener B., Otag F., Kiraz N., Kustimur S., Sancak B., Evci C., Emektas G. (2010) Molecular identification, genotyping, and drug susceptibility of the basidiomycetous yeast pathogen Trichosporon isolated from Turkish patients. Med Mycol 48: 141-6.
9. Mekha N., Sugita T., Ikeda R., Nishikawa A., Autthateinchai R., Poonwan N., Sawanpanyalert P. (2010) Genotyping and antifungal drug susceptibility of the pathogenic yeast Trichosporon asahii isolated from Thai patients. Mycopathologia 169: 67-70.
10. Rodriguez-Tudela J.L., Gomez-Lopez A., Alastruey-Izquierdo A., Mellado E., Bernal-Martinez L., Cuenca-Estrella M. (2007) Genotype distribution of clinical isolates of Trichosporon asahii based on sequencing of intergenic spacer 1. Diagn Microbiol Infect Dis 58: 435-40.
11. Sugita T., Nishikawa A., Shinoda T., Kume H. (1995) Taxonomic position of deep-seated, mucosa-associated, and superficial isolates of Trichosporon cutaneum from trichosporonosis patients. J Clin Microbiol 33: 1368-70.
12. Sugita T., Nakajima M., Ikeda R., Matsushima T., Shinoda T. (2002) Sequence analysis of the ribosomal DNA intergenic spacer 1 regions of Trichosporon species. J Clin Microbiol 40: 1826-30.
13. Sugita T., Nishikawa A., Ichikawa T., Ikeda R., Shinoda T. (2000) Isolation of Trichosporon asahii from environmental materials. Med Mycol 38: 27-30.
14. Ando M., Arima K., Yoneda R., Tamura M. (1991) Japanese summer-type hypersensitivity pneumonitis. Geographic distribution, home environment, and clinical characteristics of 621 cases. Am Rev Respir Dis 144: 765-9.
15. Ando M., Suga M., Nishiura Y., Miyajima M. (1995) Summer-type hypersensitivity pneumonitis. Intern Med 34: 707-12.
16. Shimazu K., Ando M., Sakata T., Yoshida K., Araki S. (1984) Hypersensitivity pneumonitis induced by Trichosporon cutaneum. Am Rev Respir Dis 130: 407-11.
17. Sugita T., Suto H., Unno T., Tsuboi R., Ogawa H., Shinoda T., Nishikawa A. (2001) Molecular analysis of Malassezia microflora on the skin of atopic dermatitis patients and healthy subjects. J Clin Microbiol 39: 3486-90.
18. Sugita T., Kodama M., Saito M., Ito T., Kato Y., Tsuboi R., Nishikawa A. (2003) Sequence diversity of the intergenic spacer region of the rRNA gene of Malassezia globosa colonizing the skin of patients with atopic dermatitis and healthy individuals. J Clin Microbiol 41: 3022-7.
19. Sugita T., Tajima M., Tsubuku H., Tsuboi R., Nishikawa A. (2006) Quantitative analysis of cutaneous Malassezia in atopic dermatitis patients using real-time PCR. Microbiol Immunol 50: 549-52.
20. Kustimur S., Kalkanci A., Caglar K., Dizbay M., Aktas F., Sugita T. (2002) Nosocomial fungemia due to Trichosporon asteroides: first described bloodstream infection. Diagn Microbiol Infect Dis 43: 167-70.
21. David C., Martin D.B., Deng A., Cooper J.Z. (2008) Disseminated Trichosporon inkin and Histoplasma capsulatum in a patient with newly diagnosed AIDS. J Am Acad Dermatol 59(Suppl. 1): S13-5.
22. Ramos J.M., Cuenca-Estrella M., Gutierrez F., Elia M., Rodriguez-Tudela J.L. (2004) Clinical case of endocarditis due to Trichosporon inkin and antifungal susceptibility profile of the organism. J Clin Microbiol 42: 2341-4.
23. Gedikoglu G., Aǧirbasli H., Bilgen S.K., Ozcan B., Otlu G., Sinik N., Cerikçioǧlu R., Durmaz E., Can N., Yalman H., Sugita T. (2008) Two possible cases of Trichosporon infections in bone-marrow-transplanted children: the first case of T. japonicum isolated from clinical specimens. Jpn J Infect Dis 61: 130-2.
24. Marty F.M., Barouch D.H., Coakley E.P., Baden L.R. (2003) Disseminated trichosporonosis caused by Trichosporon loubieri. J Clin Microbiol 41: 5317-20.
25. Padhye A.A., Verghese S., Ravichandran P., Balamurugan G., Hall L., Padmaja P., Fernandez M.C. (2003) Trichosporon loubieri infection in a patient with adult polycystic kidney disease. J Clin Microbiol 41: 479-82.
26. Amaya M., Tajima M., Okubo Y., Sugita T., Nishikawa A., Tsuboi R. (2007) Molecular analysis of Malassezia microflora in the lesional skin of psoriasis patients. J Dermatol 34: 619-24.
27. Morishita N., Sei Y., Sugita T. (2006) Molecular analysis of Malassezia microflora from patients with pityriasis versicolor. Mycopathologia 161: 61-5.
28. Tajima M., Sugita T., Nishikawa A., Tsuboi R. (2008) Molecular analysis of Malassezia microflora in seborrheic dermatitis patients: comparison with other diseases and healthy subjects. J Invest Dermatol 128: 345-51.
29. Ghannoum M.A., Jurevic R.J., Mukherjee P.K., Cui F., Sikaroodi M., Naqvi A., Gillevet P.M. (2010) Characterization of the oral fungal microbiome (mycobiome) in healthy individuals. PLoS Pathog 6: e1000713.
30. Diaz M.R., Boekhout T., Kiesling T., Fell J.W. (2005) Comparative analysis of the intergenic spacer regions and population structure of the species complex of the pathogenic yeast Cryptococcus neoformans. FEMS Yeast Res 5: 1129-40.
31. Ando M., Sakata T., Yoshida K., Yamasaki H., Araki S., Onoue K., Shinoda T. (1990) Serotype-related antigen of Trichosporon cutaneum in the induction of summer-type hypersensitivity pneumonitis: correlation between serotype of inhalation challenge-positive antigen and that of the isolates from patients' homes. J Allergy Clin Immunol 85: 36-44.
32. Sugita T., Ikeda R., Nishikawa A. (2004) Analysis of Trichosporon isolates obtained from the houses of patients with summer-type hypersensitivity pneumonitis. J Clin Microbiol 42: 5467-71.
33. Kamalam A., Senthamilselvi G., Ajithadas K., Thambiah A.S. (1998) Cutaneous trichosporosis. Mycopathologia 101: 167-75.
34. Yamamoto A., Serizawa S., Ito M., Sato Y. (1987) Effect of aging on sebaceous gland activity and on the fatty acid composition of wax esters. J Invest Dermatol 89: 507-12.
35. Sugita T., Suzuki M., Goto S., Nishikawa A., Hiruma M., Yamazaki T., Makimura K. (2009) Quantitative analysis of the cutaneous Malassezia microbiota in 770 healthy Japanese by age and gender using a real-time PCR assay. Med Mycol 21: 1-5.
36. Tokimatsu I. (2008) Trichosporonosis. Nippon Rinsho 66: 2362-6.