-
1
-
-
67650692734
-
Opportunities for microfluidic technologies in synthetic biology
-
Gulati, S.; Rouilly, V.; Niu, X.; Chappell, J.; Kitney, R.I.; Edel, J.B.; Freemont, P.S.; de Mello, A.J. Opportunities for microfluidic technologies in synthetic biology. J. R. Soc. Interface 2009, 6, S493-S506.
-
(2009)
J. R. Soc. Interface
, vol.6
-
-
Gulati, S.1
Rouilly, V.2
Niu, X.3
Chappell, J.4
Kitney, R.I.5
Edel, J.B.6
Freemont, P.S.7
de Mello, A.J.8
-
2
-
-
77951107086
-
Synthetic biology: Applications come of age
-
Khalil, A.S.; Collins, J.J. Synthetic biology: Applications come of age. Nat. Rev. Genet. 2010, 11, 367-379.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
3
-
-
33745454125
-
Synthetic biology: New engineering rules for an emerging discipline
-
Andrianantoandro, E.; Basu, S.; Karig, D.K.; Weiss, R. Synthetic biology: New engineering rules for an emerging discipline. Mol. Syst. Biol. 2006, 2, 2006.0028.
-
(2006)
Mol. Syst. Biol.
, vol.2
, pp. 20060028
-
-
Andrianantoandro, E.1
Basu, S.2
Karig, D.K.3
Weiss, R.4
-
4
-
-
28544451327
-
Foundations for engineering biology
-
Endy, D. Foundations for engineering biology. Nature 2005, 438, 449-453.
-
(2005)
Nature
, vol.438
, pp. 449-453
-
-
Endy, D.1
-
5
-
-
33645522086
-
Microfluidics-based systems biology
-
Breslauer, D.N.; Lee, P.J.; Lee, L.P. Microfluidics-based systems biology. Mol. Biosyst. 2006, 2, 97-112.
-
(2006)
Mol. Biosyst.
, vol.2
, pp. 97-112
-
-
Breslauer, D.N.1
Lee, P.J.2
Lee, L.P.3
-
6
-
-
68949215494
-
Microfluidic devices for measuring gene network dynamics in single cells
-
Bennett, M.R.; Hasty, J. Microfluidic devices for measuring gene network dynamics in single cells. Nat. Rev. Genet. 2009, 10, 628-638.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 628-638
-
-
Bennett, M.R.1
Hasty, J.2
-
7
-
-
0037119587
-
Stochastic gene expression in a single cell
-
Elowitz, M.B.; Levine, A.J.; Siggia, E.D.; Swain, P.S. Stochastic gene expression in a single cell. Science 2002, 297, 1183-1186.
-
(2002)
Science
, vol.297
, pp. 1183-1186
-
-
Elowitz, M.B.1
Levine, A.J.2
Siggia, E.D.3
Swain, P.S.4
-
8
-
-
64749116742
-
Using movies to analyse gene circuit dynamics in single cells
-
Locke, J.C.W.; Elowitz, M.B. Using movies to analyse gene circuit dynamics in single cells. Nat. Rev. Micro. 2009, 7, 383-392.
-
(2009)
Nat. Rev. Micro.
, vol.7
, pp. 383-392
-
-
Locke, J.C.W.1
Elowitz, M.B.2
-
9
-
-
77956650346
-
Microfluidic approaches for systems and synthetic biology
-
Szita, N.; Polizzi, K.; Jaccard, N.; Baganz, F. Microfluidic approaches for systems and synthetic biology. Curr. Opin. Biotechnol. 2010, 21, 517-523.
-
(2010)
Curr. Opin. Biotechnol.
, vol.21
, pp. 517-523
-
-
Szita, N.1
Polizzi, K.2
Jaccard, N.3
Baganz, F.4
-
10
-
-
33344476424
-
Microfluidics technology for manipulation and analysis of biological cells
-
Yi, C.; Li, C.-W.; Ji, S.; Yang, M. Microfluidics technology for manipulation and analysis of biological cells. Anal. Chim. Acta 2006, 560, 1-23.
-
(2006)
Anal. Chim. Acta
, vol.560
, pp. 1-23
-
-
Yi, C.1
Li, C.-W.2
Ji, S.3
Yang, M.4
-
11
-
-
0346373645
-
Optical manipulation of objects and biological cells in microfluidic devices
-
Ozkan, M.; Wang, M.; Ozkan, C.; Flynn, R.; Esener, S. Optical manipulation of objects and biological cells in microfluidic devices. Biomed. Microdevices 2003, 5, 61-67.
-
(2003)
Biomed. Microdevices
, vol.5
, pp. 61-67
-
-
Ozkan, M.1
Wang, M.2
Ozkan, C.3
Flynn, R.4
Esener, S.5
-
12
-
-
0034662160
-
Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping
-
Anderson, J.R.; Chiu, D.T.; Jackman, R.J.; Cherniavskaya, O.; McDonald, J.C.; Wu, H.; Whitesides, S.H.; Whitesides, G.M. Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping. Anal. Chem. 2000, 72, 3158-3164.
-
(2000)
Anal. Chem.
, vol.72
, pp. 3158-3164
-
-
Anderson, J.R.1
Chiu, D.T.2
Jackman, R.J.3
Cherniavskaya, O.4
McDonald, J.C.5
Wu, H.6
Whitesides, S.H.7
Whitesides, G.M.8
-
13
-
-
0034293766
-
Generation of solution and surface gradients using microfluidic systems
-
Jeon, N.L.; Dertinger, S.K.W.; Chiu, D.T.; Choi, I.S.; Stroock, A.D.; Whitesides, G.M. Generation of solution and surface gradients using microfluidic systems. Langmuir 2000, 16, 8311-8316.
-
(2000)
Langmuir
, vol.16
, pp. 8311-8316
-
-
Jeon, N.L.1
Dertinger, S.K.W.2
Chiu, D.T.3
Choi, I.S.4
Stroock, A.D.5
Whitesides, G.M.6
-
14
-
-
74849112398
-
Multiparameter screening on slipchip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods
-
Li, L.; Du, W.; Ismagilov, R.F. Multiparameter screening on slipchip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods. J. Am. Chem. Soc. 2009, 132, 112-119.
-
(2009)
J. Am. Chem. Soc.
, vol.132
, pp. 112-119
-
-
Li, L.1
Du, W.2
Ismagilov, R.F.3
-
15
-
-
77952964062
-
Nanoliter multiplex PCR arrays on a slipchip
-
Shen, F.; Du, W.; Davydova, E.K.; Karymov, M.A.; Pandey, J.; Ismagilov, R.F. Nanoliter multiplex PCR arrays on a slipchip. Anal. Chem. 2010, 82, 4606-4612.
-
(2010)
Anal. Chem.
, vol.82
, pp. 4606-4612
-
-
Shen, F.1
Du, W.2
Davydova, E.K.3
Karymov, M.A.4
Pandey, J.5
Ismagilov, R.F.6
-
16
-
-
0344464862
-
Development of non-destructive, non-contact single-cell based differential cell assay using on-chip microcultivation and optical tweezers
-
Wakamoto, Y.; Umehara, S.; Matsumura, K.; Inoue, I.; Yasuda, K. Development of non-destructive, non-contact single-cell based differential cell assay using on-chip microcultivation and optical tweezers. Sens. Actuators B 2003, 96, 693-700.
-
(2003)
Sens. Actuators B
, vol.96
, pp. 693-700
-
-
Wakamoto, Y.1
Umehara, S.2
Matsumura, K.3
Inoue, I.4
Yasuda, K.5
-
17
-
-
0037965621
-
A sensitive, versatile microfluidic assay for bacterial chemotaxis
-
Mao, H.; Cremer, P.S.; Manson, M.D. A sensitive, versatile microfluidic assay for bacterial chemotaxis. Proc. Natl. Acad. Sci. USA 2003, 100, 5449-5454.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5449-5454
-
-
Mao, H.1
Cremer, P.S.2
Manson, M.D.3
-
18
-
-
77951925139
-
Synthetic biology: Tools to design, build, and optimize cellular processes
-
Eric, Y.; Hal, A. Synthetic biology: Tools to design, build, and optimize cellular processes. J. Biomed. Biotech. 2010, 2010, 130781.
-
(2010)
J. Biomed. Biotech.
, vol.2010
, pp. 130781
-
-
Eric, Y.1
Hal, A.2
-
19
-
-
7944238693
-
Microfluidic biosensing systems Part II. Monitoring the dynamic production of glucose and ethanol from microchip-immobilised yeast cells using enzymatic chemiluminescent μ-biosensors
-
Davidsson, R.; Johansson, B.; Passoth, V.; Bengtsson, M.; Laurell, T.; Emneus, J. Microfluidic biosensing systems Part II. Monitoring the dynamic production of glucose and ethanol from microchip-immobilised yeast cells using enzymatic chemiluminescent μ-biosensors. Lab Chip 2004, 4, 488-494.
-
(2004)
Lab Chip
, vol.4
, pp. 488-494
-
-
Davidsson, R.1
Johansson, B.2
Passoth, V.3
Bengtsson, M.4
Laurell, T.5
Emneus, J.6
-
20
-
-
33947184356
-
Quantitative detection of protein expression in single cells using droplet microfluidics
-
Huebner, A.; Srisa-Art, M.; Holt, D.; Abell, C.; Hollfelder, F.; de Mello, A.J.; Edel, J.B. Quantitative detection of protein expression in single cells using droplet microfluidics. Chem. Commun. 2007, 1218-1220.
-
(2007)
Chem. Commun.
, pp. 1218-1220
-
-
Huebner, A.1
Srisa-Art, M.2
Holt, D.3
Abell, C.4
Hollfelder, F.5
de Mello, A.J.6
Edel, J.B.7
-
21
-
-
78049372489
-
Miniaturization and parallelization of biological and chemical assays in microfluidic devices
-
Vyawahare, S.; Griffiths, A.D.; Merten, C.A. Miniaturization and parallelization of biological and chemical assays in microfluidic devices. Chem. Biol. 2010, 17, 1052-1065.
-
(2010)
Chem. Biol.
, vol.17
, pp. 1052-1065
-
-
Vyawahare, S.1
Griffiths, A.D.2
Merten, C.A.3
-
22
-
-
79551487057
-
Droplet microfluidics: Recent developments and future applications
-
Casadevall i Solvas, X.; deMello, A. Droplet microfluidics: Recent developments and future applications. Chem. Commun. 2011, 47, 1936-1942.
-
(2011)
Chem. Commun.
, vol.47
, pp. 1936-1942
-
-
Casadevall i Solvas, X.1
deMello, A.2
-
23
-
-
70350331103
-
Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments
-
Shim, J.U.; Olguin, L.F.; Whyte, G.; Scott, D.; Babtie, A.; Abell, C.; Huck, W.T.S.; Hollfelder, F. Simultaneous determination of gene expression and enzymatic activity in individual bacterial cells in microdroplet compartments. J. Am. Chem. Soc. 2009, 131, 15251-15256.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 15251-15256
-
-
Shim, J.U.1
Olguin, L.F.2
Whyte, G.3
Scott, D.4
Babtie, A.5
Abell, C.6
Huck, W.T.S.7
Hollfelder, F.8
-
24
-
-
33845761551
-
A high-throughput microfluidic real-time gene expression living cell array
-
King, K.R.; Wang, S.H.; Irimia, D.; Jayaraman, A.; Toner, M.; Yarmush, M.L. A high-throughput microfluidic real-time gene expression living cell array. Lab Chip 2007, 7, 77-85.
-
(2007)
Lab Chip
, vol.7
, pp. 77-85
-
-
King, K.R.1
Wang, S.H.2
Irimia, D.3
Jayaraman, A.4
Toner, M.5
Yarmush, M.L.6
-
25
-
-
3242664287
-
Dynamic gene expression profiling using a microfabricated living cell array
-
Thompson, D.M.; King, K.R.; Wieder, K.J.; Toner, M.; Yarmush, M.L.; Jayaraman, A. Dynamic gene expression profiling using a microfabricated living cell array. Anal. Chem. 2004, 76, 4098-4103.
-
(2004)
Anal. Chem.
, vol.76
, pp. 4098-4103
-
-
Thompson, D.M.1
King, K.R.2
Wieder, K.J.3
Toner, M.4
Yarmush, M.L.5
Jayaraman, A.6
-
26
-
-
36749063615
-
The micro-petri dish, a million-well growth chip for the culture and high-throughput screening of microorganisms
-
Ingham, C.J.; Sprenkels, A.; Bomer, J.; Molenaar, D.; van den Berg, A.; Vlieg, J.E.T.V.; de Vos, W.M. The micro-petri dish, a million-well growth chip for the culture and high-throughput screening of microorganisms. Proc. Natl. Acad. Sci. USA 2007, 104, 18217-18222.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 18217-18222
-
-
Ingham, C.J.1
Sprenkels, A.2
Bomer, J.3
Molenaar, D.4
van den Berg, A.5
Vlieg, J.E.T.V.6
de Vos, W.M.7
-
27
-
-
33751569377
-
Microfluidics device for single cell gene expression analysis in Saccharomyces cerevisiae
-
Ryley, J.; Pereira-Smith, O.M. Microfluidics device for single cell gene expression analysis in Saccharomyces cerevisiae. Yeast 2006, 23, 1065-1073.
-
(2006)
Yeast
, vol.23
, pp. 1065-1073
-
-
Ryley, J.1
Pereira-Smith, O.M.2
-
28
-
-
40449122796
-
Nanoparticle-mediated cellular response is size-dependent
-
Jiang, W.; Kim, B.Y.S.; Rutka, J.T.; Chan, W.C.W. Nanoparticle-mediated cellular response is size-dependent. Nat. Nanotech. 2008, 3, 145-150.
-
(2008)
Nat. Nanotech.
, vol.3
, pp. 145-150
-
-
Jiang, W.1
Kim, B.Y.S.2
Rutka, J.T.3
Chan, W.C.W.4
-
29
-
-
77954661151
-
Current application of micro/nano-interfaces to stimulate and analyze cellular responses
-
Cho, Y.K.; Shin, H.; Lee, S.K.; Kim, T. Current application of micro/nano-interfaces to stimulate and analyze cellular responses. Ann. Biomed. Eng. 2010, 38, 2056-2067.
-
(2010)
Ann. Biomed. Eng.
, vol.38
, pp. 2056-2067
-
-
Cho, Y.K.1
Shin, H.2
Lee, S.K.3
Kim, T.4
-
30
-
-
4644343922
-
Bacterial persistence as a phenotypic switch
-
Balaban, N.Q.; Merrin, J.; Chait, R.; Kowalik, L.; Leibler, S. Bacterial persistence as a phenotypic switch. Science 2004, 305, 1622-1625.
-
(2004)
Science
, vol.305
, pp. 1622-1625
-
-
Balaban, N.Q.1
Merrin, J.2
Chait, R.3
Kowalik, L.4
Leibler, S.5
-
31
-
-
70349769737
-
Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability
-
Boedicker, J.Q.; Vincent, M.E.; Ismagilov, R.F. Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability. Angew. Chem. Int. Ed. 2009, 48, 5908-5911.
-
(2009)
Angew. Chem. Int. Ed.
, vol.48
, pp. 5908-5911
-
-
Boedicker, J.Q.1
Vincent, M.E.2
Ismagilov, R.F.3
-
32
-
-
0035020454
-
A rapid diffusion immunoassay in a T-sensor
-
Hatch, A.; Kamholz, A.E.; Hawkins, K.R.; Munson, M.S.; Schilling, E.A.; Weigl, B.H.; Yager, P. A rapid diffusion immunoassay in a T-sensor. Nat. Biotech. 2001, 19, 461-465.
-
(2001)
Nat. Biotech.
, vol.19
, pp. 461-465
-
-
Hatch, A.1
Kamholz, A.E.2
Hawkins, K.R.3
Munson, M.S.4
Schilling, E.A.5
Weigl, B.H.6
Yager, P.7
-
33
-
-
0023299695
-
Characterization and localization of the even-skipped protein of Drosophila
-
Frasch, M.; Hoey, T.; Rushlow, C.; Doyle, H.; Levine, M. Characterization and localization of the even-skipped protein of Drosophila. EMBO J. 1987, 6, 749-759.
-
(1987)
EMBO J.
, vol.6
, pp. 749-759
-
-
Frasch, M.1
Hoey, T.2
Rushlow, C.3
Doyle, H.4
Levine, M.5
-
34
-
-
33244485265
-
The interpretation of morphogen gradients
-
Ashe, H.L.; Briscoe, J. The interpretation of morphogen gradients. Development 2006, 133, 385-394.
-
(2006)
Development
, vol.133
, pp. 385-394
-
-
Ashe, H.L.1
Briscoe, J.2
-
35
-
-
33846300352
-
Morpheus unbound: Reimagining the morphogen gradient
-
Lander, A.D. Morpheus unbound: Reimagining the morphogen gradient. Cell 2007, 128, 245-256.
-
(2007)
Cell
, vol.128
, pp. 245-256
-
-
Lander, A.D.1
-
36
-
-
0035950105
-
Morphogen gradient interpretation
-
Gurdon, J.B.; Bourillot, P.Y. Morphogen gradient interpretation. Nature 2001, 413, 797-803.
-
(2001)
Nature
, vol.413
, pp. 797-803
-
-
Gurdon, J.B.1
Bourillot, P.Y.2
-
37
-
-
44849085110
-
A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells
-
Charvin, G.; Cross, F.R.; Siggia, E.D. A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. PLoS ONE 2008, 3, e1468.
-
(2008)
PLoS ONE
, vol.3
-
-
Charvin, G.1
Cross, F.R.2
Siggia, E.D.3
-
38
-
-
33745727459
-
A microsystem for sensing and patterning oxidative microgradients during cell culture
-
Park, J.; Bansal, T.; Pinelis, M.; Maharbiz, M.M. A microsystem for sensing and patterning oxidative microgradients during cell culture. Lab Chip 2006, 6, 611-622.
-
(2006)
Lab Chip
, vol.6
, pp. 611-622
-
-
Park, J.1
Bansal, T.2
Pinelis, M.3
Maharbiz, M.M.4
-
39
-
-
53349117682
-
Biochemistry's new look
-
Blow, N. Biochemistry's new look. Nature 2008, 455, 697-700.
-
(2008)
Nature
, vol.455
, pp. 697-700
-
-
Blow, N.1
-
40
-
-
70349459265
-
Review: Microfluidic applications in metabolomics and metabolic profiling
-
Kraly, J.R.; Holcomb, R.E.; Guan, Q.; Henry, C.S. Review: Microfluidic applications in metabolomics and metabolic profiling. Anal. Chem. Acta 2009, 653, 23-35.
-
(2009)
Anal. Chem. Acta
, vol.653
, pp. 23-35
-
-
Kraly, J.R.1
Holcomb, R.E.2
Guan, Q.3
Henry, C.S.4
-
41
-
-
41149178478
-
LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics
-
Theodoridis, G.; Gika, H.G.; Wilson, I.D. LC-MS-based methodology for global metabolite profiling in metabonomics/metabolomics. Trends Anal. Chem. 2008, 27, 251-260.
-
(2008)
Trends Anal. Chem.
, vol.27
, pp. 251-260
-
-
Theodoridis, G.1
Gika, H.G.2
Wilson, I.D.3
-
42
-
-
49149126264
-
Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity
-
Amantonico, A.; Oh, J.Y.; Sobek, J.; Heinemann, M.; Zenobi, R. Mass spectrometric method for analyzing metabolites in yeast with single cell sensitivity. Angew. Chem. Int. Ed. 2008, 47, 5382-5385.
-
(2008)
Angew. Chem. Int. Ed.
, vol.47
, pp. 5382-5385
-
-
Amantonico, A.1
Oh, J.Y.2
Sobek, J.3
Heinemann, M.4
Zenobi, R.5
-
43
-
-
70349766044
-
Coupling microdroplet microreactors with mass spectrometry: Reading the contents of single droplets online
-
Fidalgo, L.M.; Whyte, G.; Ruotolo, B.T.; Benesch, J.L.P.; Stengel, F.; Abell, C.; Robinson, C.V.; Huck, W.T.S. Coupling microdroplet microreactors with mass spectrometry: Reading the contents of single droplets online. Angew. Chem. Int. Ed. 2009, 48, 3665-3668.
-
(2009)
Angew. Chem. Int. Ed.
, vol.48
, pp. 3665-3668
-
-
Fidalgo, L.M.1
Whyte, G.2
Ruotolo, B.T.3
Benesch, J.L.P.4
Stengel, F.5
Abell, C.6
Robinson, C.V.7
Huck, W.T.S.8
-
44
-
-
77954204513
-
Microfluidic cell culture and metabolism detection with electrospray ionization quadrupole time-of-flight mass spectrometer
-
Gao, D.; Wei, H.B.; Guo, G.S.; Lin, J.M. Microfluidic cell culture and metabolism detection with electrospray ionization quadrupole time-of-flight mass spectrometer. Anal. Chem. 2010, 82, 5679-5685.
-
(2010)
Anal. Chem.
, vol.82
, pp. 5679-5685
-
-
Gao, D.1
Wei, H.B.2
Guo, G.S.3
Lin, J.M.4
-
45
-
-
55549089989
-
Microscale LC-MS-NMR platform applied to the identification of active cyanobacterial metabolites
-
Lin, Y.Q.; Schiavo, S.; Orjala, J.; Vouros, P.; Kautz, R. Microscale LC-MS-NMR platform applied to the identification of active cyanobacterial metabolites. Anal. Chem. 2008, 80, 8045-8054.
-
(2008)
Anal. Chem.
, vol.80
, pp. 8045-8054
-
-
Lin, Y.Q.1
Schiavo, S.2
Orjala, J.3
Vouros, P.4
Kautz, R.5
-
46
-
-
59749091363
-
Microfluidic technology applied to cell-wall protein analysis of olive related lactic acid bacteria
-
Lonigro, S.L.; Valerio, F.; de Angelis, M.; de Bellis, P.; Lavermicocca, P. Microfluidic technology applied to cell-wall protein analysis of olive related lactic acid bacteria. Int. J. Food Microbiol. 2009, 130, 6-11.
-
(2009)
Int. J. Food Microbiol.
, vol.130
, pp. 6-11
-
-
Lonigro, S.L.1
Valerio, F.2
de Angelis, M.3
de Bellis, P.4
Lavermicocca, P.5
-
47
-
-
33750447943
-
Metabolic monitoring of the electrically stimulated single heart cell within a microfluidic platform
-
Cheng, W.; Klauke, N.; Sedgwick, H.; Smith, G.L.; Cooper, J.M. Metabolic monitoring of the electrically stimulated single heart cell within a microfluidic platform. Lab Chip 2006, 6, 1424-1431.
-
(2006)
Lab Chip
, vol.6
, pp. 1424-1431
-
-
Cheng, W.1
Klauke, N.2
Sedgwick, H.3
Smith, G.L.4
Cooper, J.M.5
-
48
-
-
12244256381
-
Microfluidic chip toward cellular ATP and ATP-conjugated metabolic analysis with bioluminescence detection
-
Liu, B.F.; Ozaki, M.; Hisamoto, H.; Luo, Q.M.; Utsumi, Y.; Hattori, T.; Terabe, S. Microfluidic chip toward cellular ATP and ATP-conjugated metabolic analysis with bioluminescence detection. Anal. Chem. 2005, 77, 573-578.
-
(2005)
Anal. Chem.
, vol.77
, pp. 573-578
-
-
Liu, B.F.1
Ozaki, M.2
Hisamoto, H.3
Luo, Q.M.4
Utsumi, Y.5
Hattori, T.6
Terabe, S.7
-
49
-
-
64649085942
-
Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes
-
Clark, A.M.; Sousa, K.M.; Jennings, C.; MacDougald, O.A.; Kennedy, R.T. Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes. Anal. Chem. 2009, 81, 2350-2356.
-
(2009)
Anal. Chem.
, vol.81
, pp. 2350-2356
-
-
Clark, A.M.1
Sousa, K.M.2
Jennings, C.3
McDougald, O.A.4
Kennedy, R.T.5
-
50
-
-
51549114460
-
Noninvasive metabolic profiling using microfluidics for analysis of single preimplantation embryos
-
Urbanski, J.P.; Johnson, M.T.; Craig, D.D.; Potter, D.L.; Gardner, D.K.; Thorsen, T. Noninvasive metabolic profiling using microfluidics for analysis of single preimplantation embryos. Anal. Chem. 2008, 80, 6500-6507.
-
(2008)
Anal. Chem.
, vol.80
, pp. 6500-6507
-
-
Urbanski, J.P.1
Johnson, M.T.2
Craig, D.D.3
Potter, D.L.4
Gardner, D.K.5
Thorsen, T.6
-
51
-
-
43949083044
-
Development of quantitative cell-based enzyme assays in microdroplets
-
Huebner, A.; Olguin, L.F.; Bratton, D.; Whyte, G.; Huck, W.T.S.; de Mello, A.J.; Edel, J.B.; Abell, C.; Hollfelder, F. Development of quantitative cell-based enzyme assays in microdroplets. Anal. Chem. 2008, 80, 3890-3896.
-
(2008)
Anal. Chem.
, vol.80
, pp. 3890-3896
-
-
Huebner, A.1
Olguin, L.F.2
Bratton, D.3
Whyte, G.4
Huck, W.T.S.5
de Mello, A.J.6
Edel, J.B.7
Abell, C.8
Hollfelder, F.9
-
52
-
-
77955012268
-
Microchip-ESI-MS determination of dissociation constant of the lysozyme-NAG(3) complex
-
Svobodova, J.; Mathur, S.; Muck, A.; Letzel, T.; Svatos, A. Microchip-ESI-MS determination of dissociation constant of the lysozyme-NAG(3) complex. Electrophoresis 2010, 31, 2680-2685.
-
(2010)
Electrophoresis
, vol.31
, pp. 2680-2685
-
-
Svobodova, J.1
Mathur, S.2
Muck, A.3
Letzel, T.4
Svatos, A.5
-
53
-
-
18144416899
-
Microchip HPLC of peptides and proteins
-
Reichmuth, D.S.; Shepodd, T.J.; Kirby, B.J. Microchip HPLC of peptides and proteins. Anal. Chem. 2005, 77, 2997-3000.
-
(2005)
Anal. Chem.
, vol.77
, pp. 2997-3000
-
-
Reichmuth, D.S.1
Shepodd, T.J.2
Kirby, B.J.3
-
54
-
-
57449090900
-
Defined spatial structure stabilizes a synthetic multispecies bacterial community
-
Kim, H.J.; Boedicker, J.Q.; Choi, J.W.; Ismagilov, R.F. Defined spatial structure stabilizes a synthetic multispecies bacterial community. Proc. Natl. Acad. Sci. USA 2008, 105, 18188-18193.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18188-18193
-
-
Kim, H.J.1
Boedicker, J.Q.2
Choi, J.W.3
Ismagilov, R.F.4
-
55
-
-
77950560416
-
Use of Ichip for high-throughput in situ cultivation of "uncultivable" microbial species
-
Nichols, D.; Cahoon, N.; Trakhtenberg, E.M.; Pham, L.; Mehta, A.; Belanger, A.; Kanigan, T.; Lewis, K.; Epstein, S.S. Use of Ichip for high-throughput in situ cultivation of "uncultivable" microbial species. Appl. Environ. Microbiol. 2010, 76, 2445-2450.
-
(2010)
Appl. Environ. Microbiol.
, vol.76
, pp. 2445-2450
-
-
Nichols, D.1
Cahoon, N.2
Trakhtenberg, E.M.3
Pham, L.4
Mehta, A.5
Belanger, A.6
Kanigan, T.7
Lewis, K.8
Epstein, S.S.9
-
56
-
-
0034699508
-
Commercial high speed machines open new opportunities in high throughput flow cytometry (HTFC)
-
Ashcroft, R.G.; Lopez, P.A. Commercial high speed machines open new opportunities in high throughput flow cytometry (HTFC). J. Immunol. Methods 2000, 243, 13-24.
-
(2000)
J. Immunol. Methods
, vol.243
, pp. 13-24
-
-
Ashcroft, R.G.1
Lopez, P.A.2
-
57
-
-
21144433632
-
Microfluidic sorting of mammalian cells by optical force switching
-
Wang, M.M.; Tu, E.; Raymond, D.E.; Yang, J.M.; Zhang, H.C.; Hagen, N.; Dees, B.; Mercer, E.M.; Forster, A.H.; Kariv, I.; Marchand, P.J.; Butler, W.F. Microfluidic sorting of mammalian cells by optical force switching. Nat. Biotech. 2005, 23, 83-87.
-
(2005)
Nat. Biotech.
, vol.23
, pp. 83-87
-
-
Wang, M.M.1
Tu, E.2
Raymond, D.E.3
Yang, J.M.4
Zhang, H.C.5
Hagen, N.6
Dees, B.7
Mercer, E.M.8
Forster, A.H.9
Kariv, I.10
Marchand, P.J.11
Butler, W.F.12
-
58
-
-
0032738825
-
A microfabricated fluorescence-activated cell sorter
-
Fu, A.Y.; Spence, C.; Scherer, A.; Arnold, F.H.; Quake, S.R. A microfabricated fluorescence-activated cell sorter. Nat. Biotech. 1999, 17, 1109-1111.
-
(1999)
Nat. Biotech.
, vol.17
, pp. 1109-1111
-
-
Fu, A.Y.1
Spence, C.2
Scherer, A.3
Arnold, F.H.4
Quake, S.R.5
-
59
-
-
33645512804
-
Paramagnetic capture mode magnetophoretic microseparator for high efficiency blood cell separations
-
Han, K.H.; Frazier, A.B. Paramagnetic capture mode magnetophoretic microseparator for high efficiency blood cell separations. Lab Chip 2006, 6, 265-273.
-
(2006)
Lab Chip
, vol.6
, pp. 265-273
-
-
Han, K.H.1
Frazier, A.B.2
-
60
-
-
19144368234
-
Continuous microfluidic immunomagnetic cell separation
-
Inglis, D.W.; Riehn, R.; Austin, R.H.; Sturm, J.C. Continuous microfluidic immunomagnetic cell separation. Appl. Phys. Lett. 2004, 85, 5093-5095.
-
(2004)
Appl. Phys. Lett.
, vol.85
, pp. 5093-5095
-
-
Inglis, D.W.1
Riehn, R.2
Austin, R.H.3
Sturm, J.C.4
-
61
-
-
33746626506
-
Continuous sorting of magnetic cells via on-chip free-flow magnetophoresis
-
Pamme, N.; Wilhelm, C. Continuous sorting of magnetic cells via on-chip free-flow magnetophoresis. Lab Chip 2006, 6, 974-980.
-
(2006)
Lab Chip
, vol.6
, pp. 974-980
-
-
Pamme, N.1
Wilhelm, C.2
-
62
-
-
0031791260
-
Immunomagnetic cell sorting-pushing the limits
-
Thiel, A.; Scheffold, A.; Radbruch, A. Immunomagnetic cell sorting-pushing the limits. Immunotechnology 1998, 4, 89-96.
-
(1998)
Immunotechnology
, vol.4
, pp. 89-96
-
-
Thiel, A.1
Scheffold, A.2
Radbruch, A.3
-
63
-
-
33749510846
-
Deterministic hydrodynamics: Taking blood apart
-
Davis, J.A.; Inglis, D.W.; Morton, K.J.; Lawrence, D.A.; Huang, L.R.; Chou, S.Y.; Sturm, J.C.; Austin, R.H. Deterministic hydrodynamics: Taking blood apart. Proc. Natl. Acad. Sci. USA 2006, 103, 14779-14784.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14779-14784
-
-
Davis, J.A.1
Inglis, D.W.2
Morton, K.J.3
Lawrence, D.A.4
Huang, L.R.5
Chou, S.Y.6
Sturm, J.C.7
Austin, R.H.8
-
64
-
-
33644848684
-
Microfluidic diffusive filter for apheresis (leukapheresis)
-
Sethu, P.; Sin, A.; Toner, M. Microfluidic diffusive filter for apheresis (leukapheresis). Lab Chip 2006, 6, 83-89.
-
(2006)
Lab Chip
, vol.6
, pp. 83-89
-
-
Sethu, P.1
Sin, A.2
Toner, M.3
-
65
-
-
35548941139
-
Continuous blood cell separation by hydrophoretic filtration
-
Choi, S.; Song, S.; Choi, C.; Park, J.K. Continuous blood cell separation by hydrophoretic filtration. Lab Chip 2007, 7, 1532-1538.
-
(2007)
Lab Chip
, vol.7
, pp. 1532-1538
-
-
Choi, S.1
Song, S.2
Choi, C.3
Park, J.K.4
-
66
-
-
64749084287
-
K. Microfluidic self-sorting of mammalian cells to achieve cell cycle synchrony by hydrophoresis
-
Choi, S.; Song, S.; Choi, C.; Park, J. K. Microfluidic self-sorting of mammalian cells to achieve cell cycle synchrony by hydrophoresis. Anal. Chem. 2009, 81, 1964-1968.
-
(2009)
Anal. Chem.
, vol.81
, pp. 1964-1968
-
-
Choi, S.1
Song, S.2
Choi, C.3
Park, J.4
-
67
-
-
2342619619
-
Continuous particle separation through deterministic lateral displacement
-
Huang, L.R.; Cox, E.C.; Austin, R.H.; Sturm, J.C. Continuous particle separation through deterministic lateral displacement. Science 2004, 304, 987-990.
-
(2004)
Science
, vol.304
, pp. 987-990
-
-
Huang, L.R.1
Cox, E.C.2
Austin, R.H.3
Sturm, J.C.4
-
68
-
-
78449272154
-
Diffusion-based and long-range concentration gradients of multiple chemicals for bacterial chemotaxis assays
-
Kim, M.; Kim, T. Diffusion-based and long-range concentration gradients of multiple chemicals for bacterial chemotaxis assays. Anal. Chem. 2010, 82, 9401-9409.
-
(2010)
Anal. Chem.
, vol.82
, pp. 9401-9409
-
-
Kim, M.1
Kim, T.2
-
69
-
-
24044453695
-
A microfluidic chemostat for experiments with bacterial and yeast cells
-
Groisman, A.; Lobo, C.; Cho, H.J.; Campbell, J.K.; Dufour, Y.S.; Stevens, A.M.; Levchenko, A. A microfluidic chemostat for experiments with bacterial and yeast cells. Nat. Methods 2005, 2, 685-689.
-
(2005)
Nat. Methods
, vol.2
, pp. 685-689
-
-
Groisman, A.1
Lobo, C.2
Cho, H.J.3
Campbell, J.K.4
Dufour, Y.S.5
Stevens, A.M.6
Levchenko, A.7
-
70
-
-
79952649571
-
High-throughput cell cycle synchronization using inertial forces in spiral microchannels
-
Lee, W.C.; Bhagat, A.A.S.; Huang, S.; Vliet, K.J.V.; Han, J.; Lim, C.T. High-throughput cell cycle synchronization using inertial forces in spiral microchannels. Lab Chip 2007, 11, 1359-1367.
-
(2007)
Lab Chip
, vol.11
, pp. 1359-1367
-
-
Lee, W.C.1
Bhagat, A.A.S.2
Huang, S.3
Vliet, K.J.V.4
Han, J.5
Lim, C.T.6
-
71
-
-
77953584054
-
Creation of a bacterial cell controlled by a chemically synthesized genome
-
Gibson, D.G.; Glass, J.I.; Lartigue, C.; Noskov, V.N.; Chuang, R.Y.; Algire, M.A.; Benders, G.A.; Montague, M.G.; Ma, L.; Moodie, M.M.; Merryman, C.; Vashee, S.; Krishnakumar, R.; Assad-Garcia, N.; Andrews-Pfannkoch, C.; Denisova, E.A.; Young, L.; Qi, Z.Q.; Segall-Shapiro, T.H.; Calvey, C.H.; Parmar, P.P.; Hutchison, C.A.; Smith, H.O.; Venter, J.C. Creation of a bacterial cell controlled by a chemically synthesized genome. Science 2010, 329, 52-56.
-
(2010)
Science
, vol.329
, pp. 52-56
-
-
Gibson, D.G.1
Glass, J.I.2
Lartigue, C.3
Noskov, V.N.4
Chuang, R.Y.5
Algire, M.A.6
Benders, G.A.7
Montague, M.G.8
Ma, L.9
Moodie, M.M.10
Merryman, C.11
Vashee, S.12
Krishnakumar, R.13
Assad-Garcia, N.14
Andrews-Pfannkoch, C.15
Denisova, E.A.16
Young, L.17
Qi, Z.Q.18
Segall-Shapiro, T.H.19
Calvey, C.H.20
Parmar, P.P.21
Hutchison, C.A.22
Smith, H.O.23
Venter, J.C.24
more..
-
72
-
-
68949161807
-
Programming cells by multiplex genome engineering and accelerated evolution
-
Wang, H.H.; Isaacs, F.J.; Carr, P.A.; Sun, Z.Z.; Xu, G.; Forest, C.R.; Church, G.M. Programming cells by multiplex genome engineering and accelerated evolution. Nature 2009, 460, 894-898.
-
(2009)
Nature
, vol.460
, pp. 894-898
-
-
Wang, H.H.1
Isaacs, F.J.2
Carr, P.A.3
Sun, Z.Z.4
Xu, G.5
Forest, C.R.6
Church, G.M.7
-
73
-
-
67650680854
-
Synthetic biology: History, challenges and prospects
-
Haseloff, J.; Ajioka, J. Synthetic biology: History, challenges and prospects. J. R. Soc. Interface 2009, 6, S389-S391.
-
(2009)
J. R. Soc. Interface
, vol.6
-
-
Haseloff, J.1
Ajioka, J.2
-
74
-
-
68049115775
-
A new revolution? The place of systems biology and synthetic biology in the history of biology
-
Morange, M. A new revolution? The place of systems biology and synthetic biology in the history of biology. EMBO Rep. 2009, 10, S50-S53.
-
(2009)
EMBO Rep.
, vol.10
-
-
Morange, M.1
-
75
-
-
0034235973
-
Integrated system for rapid PCR-based DNA analysis in microfluidic devices
-
Khandurina, J.; McKnight, T.E.; Jacobson, S.C.; Waters, L.C.; Foote, R.S.; Ramsey, J.M. Integrated system for rapid PCR-based DNA analysis in microfluidic devices. Anal. Chem. 2000, 72, 2995-3000.
-
(2000)
Anal. Chem.
, vol.72
, pp. 2995-3000
-
-
Khandurina, J.1
McKnight, T.E.2
Jacobson, S.C.3
Waters, L.C.4
Foote, R.S.5
Ramsey, J.M.6
-
76
-
-
45849087630
-
High throughput gene expression measurement with real time PCR in a microfluidic dynamic array
-
Spurgeon, S.L.; Jones, R.C.; Ramakrishnan, R. High throughput gene expression measurement with real time PCR in a microfluidic dynamic array. PLoS ONE 2008, 3, e1662.
-
(2008)
PLoS ONE
, vol.3
-
-
Spurgeon, S.L.1
Jones, R.C.2
Ramakrishnan, R.3
-
77
-
-
0037309137
-
Microfluidic devices for DNA sequencing: Sample preparation and electrophoretic analysis
-
Paegel, B.M.; Blazej, R.G.; Mathies, R.A. Microfluidic devices for DNA sequencing: Sample preparation and electrophoretic analysis. Curr. Opin. Biotechnol. 2003, 14, 42-50.
-
(2003)
Curr. Opin. Biotechnol.
, vol.14
, pp. 42-50
-
-
Paegel, B.M.1
Blazej, R.G.2
Mathies, R.A.3
-
78
-
-
57849167393
-
Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays
-
Bau, S.; Schracke, N.; Kranzle, M.; Wu, H.; Stahler, P.; Hoheisel, J.; Beier, M.; Summerer, D. Targeted next-generation sequencing by specific capture of multiple genomic loci using low-volume microfluidic DNA arrays. Anal. Bioanal. Chem. 2009, 393, 171-175.
-
(2009)
Anal. Bioanal. Chem.
, vol.393
, pp. 171-175
-
-
Bau, S.1
Schracke, N.2
Kranzle, M.3
Wu, H.4
Stahler, P.5
Hoheisel, J.6
Beier, M.7
Summerer, D.8
-
79
-
-
70149096883
-
Droplet microfluidic technology for single-cell high-throughput screening
-
Brouzes, E.; Medkova, M.; Savenelli, N.; Marran, D.; Twardowski, M.; Hutchison, J.B.; Rothberg, J.M.; Link, D.R.; Perrimon, N.; Samuels, M.L. Droplet microfluidic technology for single-cell high-throughput screening. Proc. Natl. Acad. Sci. USA 2009, 106, 14195-14200.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 14195-14200
-
-
Brouzes, E.1
Medkova, M.2
Savenelli, N.3
Marran, D.4
Twardowski, M.5
Hutchison, J.B.6
Rothberg, J.M.7
Link, D.R.8
Perrimon, N.9
Samuels, M.L.10
-
80
-
-
77949824821
-
High-throughput automated droplet microfluidic system for screening of reaction conditions
-
Churski, K.; Korczyk, P.; Garstecki, P. High-throughput automated droplet microfluidic system for screening of reaction conditions. Lab Chip 2010, 10, 816-818.
-
(2010)
Lab Chip
, vol.10
, pp. 816-818
-
-
Churski, K.1
Korczyk, P.2
Garstecki, P.3
-
81
-
-
75149179483
-
Microfluidic devices for cell based high throughput screening
-
Upadhyaya, S.; Selvaganapathy, P.R. Microfluidic devices for cell based high throughput screening. Lab Chip 2010, 10, 341-348.
-
(2010)
Lab Chip
, vol.10
, pp. 341-348
-
-
Upadhyaya, S.1
Selvaganapathy, P.R.2
-
82
-
-
67649396057
-
Microfluidic culture of single human embryonic stem cell colonies
-
Villa-Diaz, L.G.; Torisawa, Y.S.; Uchida, T.; Ding, J.; Nogueira-De-Souza, N.C.; O'Shea, K.S.; Takayama, S.; Smith, G.D. Microfluidic culture of single human embryonic stem cell colonies. Lab Chip 2009, 9, 1749-1755.
-
(2009)
Lab Chip
, vol.9
, pp. 1749-1755
-
-
Villa-Diaz, L.G.1
Torisawa, Y.S.2
Uchida, T.3
Ding, J.4
Nogueira-De-Souza, N.C.5
O'Shea, K.S.6
Takayama, S.7
Smith, G.D.8
-
83
-
-
79959715340
-
Microfluidic engineering of stem cell niches and 3D tissue models
-
Takayama, S. Microfluidic engineering of stem cell niches and 3D tissue models. In Vitro Cell Dev. Biol. Anim. 2010, 46, S77.
-
(2010)
In Vitro Cell Dev. Biol. Anim.
, vol.46
-
-
Takayama, S.1
-
84
-
-
77949656711
-
Microfluidic techniques for dynamic single-cell analysis
-
Wang, Y.; Chen, Z.Z.; Li, Q.L. Microfluidic techniques for dynamic single-cell analysis. Microchim. Acta 2010, 168, 177-195.
-
(2010)
Microchim. Acta
, vol.168
, pp. 177-195
-
-
Wang, Y.1
Chen, Z.Z.2
Li, Q.L.3
-
85
-
-
79251593872
-
Synthetic multicellular cell-to-cell communication in inkjet printed bacterial cell systems
-
Choi, W.S.; Ha, D.; Park, S.; Kim, T. Synthetic multicellular cell-to-cell communication in inkjet printed bacterial cell systems. Biomaterials 2011, 32, 2500-2507.
-
(2011)
Biomaterials
, vol.32
, pp. 2500-2507
-
-
Choi, W.S.1
Ha, D.2
Park, S.3
Kim, T.4
-
86
-
-
77950374540
-
Capillary based patterning of cellular communities in laterally open channels
-
Lee, S.H.; Heinz, A.J.; Shin, S.; Jung, Y.G.; Choi, S.E.; Park, W.; Roe, J.H.; Kwon, S. Capillary based patterning of cellular communities in laterally open channels. Anal. Chem. 2010, 82, 2900-2906.
-
(2010)
Anal. Chem.
, vol.82
, pp. 2900-2906
-
-
Lee, S.H.1
Heinz, A.J.2
Shin, S.3
Jung, Y.G.4
Choi, S.E.5
Park, W.6
Roe, J.H.7
Kwon, S.8
-
87
-
-
78650689883
-
High-throughput enzymatic hydrolysis of lignocellulosic biomass via in-situ regeneration
-
Bharadwaj, R.; Wong, A.; Knierim, B.; Singh, S.; Holmes, B.M.; Auer, M.; Simmons, B.A.; Adams, P.D.; Singh, A.K. High-throughput enzymatic hydrolysis of lignocellulosic biomass via in-situ regeneration. Bioresour. Technol. 2011, 102, 1329-1337.
-
(2011)
Bioresour. Technol.
, vol.102
, pp. 1329-1337
-
-
Bharadwaj, R.1
Wong, A.2
Knierim, B.3
Singh, S.4
Holmes, B.M.5
Auer, M.6
Simmons, B.A.7
Adams, P.D.8
Singh, A.K.9
-
88
-
-
78449268868
-
Microfluidic glycosyl hydrolase screening for biomass-to-biofuel conversion
-
Bharadwaj, R.; Chen, Z.W.; Datta, S.; Holmes, B.M.; Sapra, R.; Simmons, B.A.; Adams, P.D.; Singh, A.K. Microfluidic glycosyl hydrolase screening for biomass-to-biofuel conversion. Anal. Chem. 2010, 82, 9513-9520.
-
(2010)
Anal. Chem.
, vol.82
, pp. 9513-9520
-
-
Bharadwaj, R.1
Chen, Z.W.2
Datta, S.3
Holmes, B.M.4
Sapra, R.5
Simmons, B.A.6
Adams, P.D.7
Singh, A.K.8
-
89
-
-
21644441288
-
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat
-
Balagadde, F.K.; You, L.C.; Hansen, C.L.; Arnold, F.H.; Quake, S.R. Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. Science 2005, 309, 137-140.
-
(2005)
Science
, vol.309
, pp. 137-140
-
-
Balagadde, F.K.1
You, L.C.2
Hansen, C.L.3
Arnold, F.H.4
Quake, S.R.5
|