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Volumn 57, Issue 4, 2011, Pages 354-363

Mechanisms and clinical implications of the placebo effect: Is there a potential for the elderly? A mini-review

Author keywords

Aging; clinical implications; Neurobiology; Nocebo; Placebo; Placebo effect

Indexed keywords

CYCLOSPORIN A; NALOXONE; PLACEBO;

EID: 79959655977     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000322090     Document Type: Review
Times cited : (32)

References (62)
  • 2
    • 76749169724 scopus 로고    scopus 로고
    • Biological, clinical, and ethical advances of placebo effects
    • Finniss DG, Kaptchuk TJ, Miller F, Benedetti F: Biological, clinical, and ethical advances of placebo effects. Lancet 2010; 375: 686-695.
    • (2010) Lancet , vol.375 , pp. 686-695
    • Finniss, D.G.1    Kaptchuk, T.J.2    Miller, F.3    Benedetti, F.4
  • 3
    • 77049242855 scopus 로고
    • The powerful placebo
    • Beecher HK: The powerful placebo. JAMA 1955; 159:1602-1606.
    • (1955) JAMA , vol.159 , pp. 1602-1606
    • Beecher, H.K.1
  • 5
    • 41549119566 scopus 로고    scopus 로고
    • A comprehensive review of the placebo effect: Recent advances and current thought
    • Price DD, Finniss DG, Benedetti F: A comprehensive review of the placebo effect: recent advances and current thought. Annu Rev Psychol 2008; 59: 565-590.
    • (2008) Annu Rev Psychol , vol.59 , pp. 565-590
    • Price, D.D.1    Finniss, D.G.2    Benedetti, F.3
  • 6
    • 0034984127 scopus 로고    scopus 로고
    • Response expectancies in placebo analgesia and their clinical relevance
    • DOI 10.1016/S0304-3959(01)00296-2, PII S0304395901002962
    • Pollo A, Amanzio M, Arslanian A, Casadio C, Maggi G, Benedetti F: Response expectancies in placebo analgesia and their clinical relevance. Pain 2001; 93: 77-84. (Pubitemid 32530845)
    • (2001) Pain , vol.93 , Issue.1 , pp. 77-84
    • Pollo, A.1    Amanzio, M.2    Arslanian, A.3    Casadio, C.4    Maggi, G.5    Benedetti, F.6
  • 7
    • 0342902205 scopus 로고    scopus 로고
    • Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment
    • DOI 10.1056/NEJM200105243442106
    • Hrobjartsson A, Gotzsche PC: Is the placebo powerless? Ananalysis of clinical trials comparing placebo with no treatment. N Engl J Med 2001; 344: 1594-1602. (Pubitemid 32479913)
    • (2001) New England Journal of Medicine , vol.344 , Issue.21 , pp. 1594-1602
    • Hrobjartsson, A.1    Gotzsche, P.C.2
  • 8
    • 0036803108 scopus 로고    scopus 로고
    • A comparison of placebo effects in clinical analgesic trials versus studies of placebo analgesia
    • DOI 10.1016/S0304-3959(02)00205-1, PII S0304395902002051
    • vase L, Riley JL, Price DD: A comparison of placebo effects in clinical analgesic trials versus studies of placebo analgesia. Pain 2002; 99: 443-452. (Pubitemid 35284275)
    • (2002) Pain , vol.99 , Issue.3 , pp. 443-452
    • Vase, L.1    Riley III, J.L.2    Price, D.D.3
  • 9
    • 69049108631 scopus 로고    scopus 로고
    • Factors contributing to large analgesic effects in placebo mechanism studies conducted between 2002 and 2007
    • vase L, Petersen GL, Riley JL 3rd, Price DD: Factors contributing to large analgesic effects in placebo mechanism studies conducted between 2002 and 2007. Pain 2009; 145: 36-44.
    • (2009) Pain , vol.145 , pp. 36-44
    • Vase, L.1    Petersen, G.L.2    Riley III, J.L.3    Price, D.D.4
  • 10
    • 0141850172 scopus 로고    scopus 로고
    • Reversal of visceral and cutaneous hyperalgesia by local rectal anesthesia in irritable bowel syndrome (IBS) patients
    • DOI 10.1016/S0304-3959(03)00210-0
    • verne GN, Robinson ME, vase L, Price DD: Reversal of visceral and cutaneous hyperalgesia by local rectal anesthesia in irritable bowel syndrome patients. Pain 2003; 105: 223-230. (Pubitemid 37173409)
    • (2003) Pain , vol.105 , Issue.1-2 , pp. 223-230
    • Verne, G.N.1    Robinson, M.E.2    Vase, L.3    Price, D.D.4
  • 11
    • 19444387826 scopus 로고    scopus 로고
    • Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms
    • DOI 10.1016/j.pain.2005.03.014, PII S0304395905001247
    • vase L, Robinson ME, verne GN, Price DD: Increased placebo analgesia over time in irritable bowel syndrome patients is associated with desire and expectation but not endogenous opioid mechanisms. Pain 2005; 115: 338-347. (Pubitemid 40725290)
    • (2005) Pain , vol.115 , Issue.3 , pp. 338-347
    • Vase, L.1    Robinson, M.E.2    Verne, G.N.3    Price, D.D.4
  • 12
    • 0024344138 scopus 로고
    • Conditioned response models of placebo phenomena: Further support
    • DOI 10.1016/0304-3959(89)90080-8
    • voudouris NJ, Peck CL, Coleman G: Conditioned response models of placebo phenomena: further support. Pain 1989; 38:109-116. (Pubitemid 19184846)
    • (1989) Pain , vol.38 , Issue.1 , pp. 109-116
    • Voudouris, N.J.1    Peck, C.L.2    Coleman, G.3
  • 13
    • 0030791869 scopus 로고    scopus 로고
    • Classical conditioning and the placebo effect
    • DOI 10.1016/S0304-3959(97)00016-X, PII S030439599700016X
    • Montgomery GH, Kirsch I: Classical conditioning and the placebo effect. Pain 1997; 72: 107-113. (Pubitemid 27321908)
    • (1997) Pain , vol.72 , Issue.1-2 , pp. 107-113
    • Montgomery, G.H.1    Kirsch, I.2
  • 14
    • 33846804457 scopus 로고    scopus 로고
    • Classical conditioning and expectancy in placebo hypoalgesia: A randomized controlled study in patients with atopic dermatitis and persons with healthy skin
    • DOI 10.1016/j.pain.2006.08.025, PII S0304395906004519
    • Klinger R, Soost S, Flor H, Worm M: Classical conditioning and expectancy in placebo hypoalgesia: a randomized controlled study in patients with atopic dermatitis and persons with healthy skin. Pain 2007; 128:31-39. (Pubitemid 46216597)
    • (2007) Pain , vol.128 , Issue.1-2 , pp. 31-39
    • Klinger, R.1    Soost, S.2    Flor, H.3    Worm, M.4
  • 15
    • 0036220494 scopus 로고    scopus 로고
    • The contribution of suggestibility and expectation to placebo analgesia phenomenon in an experimental setting
    • DOI 10.1016/S0304-3959(01)00485-7, PII S0304395901004857
    • De Pascalis v, Chiaradia C, Carotenuto E: The contribution of suggestibility and expectation to placebo analgesia phenomenon in an experimental setting. Pain 2002; 96: 393-402. (Pubitemid 34327888)
    • (2002) Pain , vol.96 , Issue.3 , pp. 393-402
    • De Pascalis, V.1    Chiaradia, C.2    Carotenuto, E.3
  • 16
    • 0141515776 scopus 로고    scopus 로고
    • The contributions of suggestion, desire, and expectation to placebo effects in irritable bowel syndrome patients: An empirical investigation
    • DOI 10.1016/S0304-3959(03)00073-3
    • vase L, Robinson ME, verne GN, Price DD: The contributions of suggestion, desire, and expectation to placebo effects in irritable bowel syndrome patients. An empirical investigation. Pain 2003; 105:17-25. (Pubitemid 37162469)
    • (2003) Pain , vol.105 , Issue.1-2 , pp. 17-25
    • Vase, L.1    Robinson, M.E.2    Verne, G.N.3    Price, D.D.4
  • 17
    • 41749094029 scopus 로고    scopus 로고
    • The role of learning in nocebo and placebo effects
    • Colloca L, Sigaudo M, Benedetti F: The role of learning in nocebo and placebo effects. Pain 2008; 136: 211-218.
    • (2008) Pain , vol.136 , pp. 211-218
    • Colloca, L.1    Sigaudo, M.2    Benedetti, F.3
  • 18
    • 33746807812 scopus 로고    scopus 로고
    • How prior experience shapes placebo analgesia
    • DOI 10.1016/j.pain.2006.04.005, PII S0304395906001941
    • Colloca L, Benedetti F: How prior experience shapes placebo analgesia. Pain 2006; 124: 126-133. (Pubitemid 44176203)
    • (2006) Pain , vol.124 , Issue.1-2 , pp. 126-133
    • Colloca, L.1    Benedetti, F.2
  • 19
    • 0032938389 scopus 로고    scopus 로고
    • Neuropharmacological dissection of placebo analgesia: Expectation- activated opioid systems versus conditioning-activated specific subsystems
    • Amanzio M, Benedetti F: Neuropharmaco-logical dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems. J Neurosci 1999; 19: 484-494. (Pubitemid 29028987)
    • (1999) Journal of Neuroscience , vol.19 , Issue.1 , pp. 484-494
    • Amanzio, M.1    Benedetti, F.2
  • 20
    • 0037704429 scopus 로고    scopus 로고
    • Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses
    • Benedetti F, Pollo A, Lopiano L, Lanotte M, vighetti S, Rainero I: Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses. J Neurosci 2003; 23: 4315-4323. (Pubitemid 36958452)
    • (2003) Journal of Neuroscience , vol.23 , Issue.10 , pp. 4315-4323
    • Benedetti, F.1    Pollo, A.2    Lopiano, L.3    Lanotte, M.4    Vighetti, S.5    Rainero, I.6
  • 22
    • 67349133164 scopus 로고    scopus 로고
    • Placebo analgesia induced by social observational learning
    • Colloca L, Benedetti F: Placebo analgesia induced by social observational learning. Pain 2009; 144:28-34.
    • (2009) Pain , vol.144 , pp. 28-34
    • Colloca, L.1    Benedetti, F.2
  • 25
    • 34247369280 scopus 로고    scopus 로고
    • Further evidence for individual differences in placebo responding: An interactionist perspective
    • DOI 10.1016/j.jpsychores.2006.12.005, PII S0022399906005319
    • Geers AL, Kosbab K, Helfer SG, Weiland PE, Wellman JA: Further evidence for individual differences in placebo responding: an inter-actionist perspective. J Psychosom Res 2007; 62: 563-570. (Pubitemid 46635471)
    • (2007) Journal of Psychosomatic Research , vol.62 , Issue.5 , pp. 563-570
    • Geers, A.L.1    Kosbab, K.2    Helfer, S.G.3    Weiland, P.E.4    Wellman, J.A.5
  • 26
    • 70349772939 scopus 로고    scopus 로고
    • Reproducibility of placebo analgesia: Effect of dispositional optimism
    • Morton DL, Watson A, El-Deredy W, Jones AK: Reproducibility of placebo analgesia: effect of dispositional optimism. Pain 2009; 146: 194-198.
    • (2009) Pain , vol.146 , pp. 194-198
    • Morton, D.L.1    Watson, A.2    El-Deredy, W.3    Jones, A.K.4
  • 27
    • 0018185529 scopus 로고
    • The narcotic antagonist naloxone enhances clinical pain
    • DOI 10.1038/272826a0
    • Levine JD, Gordon NC, Jones RT, Fields HL: The narcotic antagonist naloxone enhances clinical pain. Nature 1978; 272: 826-827. (Pubitemid 8316990)
    • (1978) Nature , vol.272 , Issue.5656 , pp. 826-827
    • Levine, J.D.1    Gordon, N.C.2    Jones, R.T.3    Fields, H.L.4
  • 28
    • 0036500024 scopus 로고    scopus 로고
    • Placebo and opioid analgesia - Imaging a shared neuronal network
    • DOI 10.1126/science.1067176
    • Petrovic P, Kalso E, Petersson KM, Ingvar M: Placebo and opioid analgesia - imaging a shared neuronal network. Science 2002; 295: 1737-1740. (Pubitemid 34202913)
    • (2002) Science , vol.295 , Issue.5560 , pp. 1737-1740
    • Petrovic, P.1    Kalso, E.2    Petersson, K.M.3    Ingvar, M.4
  • 30
  • 31
    • 30544433435 scopus 로고    scopus 로고
    • Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network
    • DOI 10.1016/j.pain.2005.08.027, PII S030439590500552X
    • Bingel U, Lorenz J, Schoell E, Weiller C, Buchel C: Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain 2006; 120:8-15. (Pubitemid 43078587)
    • (2006) Pain , vol.120 , Issue.1-2 , pp. 8-15
    • Bingel, U.1    Lorenz, J.2    Schoell, E.3    Weiller, C.4    Buchel, C.5
  • 33
    • 0018240415 scopus 로고
    • The mechanism of placebo analgesia
    • Levine JD, Gordon NC, Fields HL: The mechanism of placebo analgesia. Lancet 1978; 2:654-657. (Pubitemid 9048375)
    • (1978) Lancet , vol.2 , Issue.8091 , pp. 654-657
    • Levine, J.D.1    Gordon, N.C.2    Fields, H.L.3
  • 35
    • 32944461856 scopus 로고    scopus 로고
    • Loss of expectation-related mechanisms in Alzheimer's disease makes analgesic therapies less effective
    • DOI 10.1016/j.pain.2005.12.016, PII S030439590500638X
    • Benedetti F, Arduino C, Costa S, vighetti S, Tarenzi L, Rainero I, Asteggiano G: Loss of expectation-related mechanisms in Alz heimer's disease makes analgesic therapies less effective. Pain 2006; 121: 133-144. (Pubitemid 43261640)
    • (2006) Pain , vol.121 , Issue.1-2 , pp. 133-144
    • Benedetti, F.1    Arduino, C.2    Costa, S.3    Vighetti, S.4    Tarenzi, L.5    Rainero, I.6    Asteggiano, G.7
  • 36
    • 0036500024 scopus 로고    scopus 로고
    • Placebo and opioid analgesia - Imaging a shared neuronal network
    • DOI 10.1126/science.1067176
    • Petrovic P, Kalso E, Petersson KM, Ingvar M: Placebo and opioid analgesia - imaging a shared neuronal network. Science 2002; 295: 1737-1740. (Pubitemid 34202913)
    • (2002) Science , vol.295 , Issue.5560 , pp. 1737-1740
    • Petrovic, P.1    Kalso, E.2    Petersson, K.M.3    Ingvar, M.4
  • 37
    • 33845599980 scopus 로고    scopus 로고
    • Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients
    • DOI 10.1016/j.pain.2006.08.001, PII S0304395906004039
    • Price DD, Craggs J, verne GN, Perlstein WM, Robinson ME: Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients. Pain 2007; 127:63-72. (Pubitemid 44959430)
    • (2007) Pain , vol.127 , Issue.1-2 , pp. 63-72
    • Price, D.D.1    Craggs, J.2    Nicholas Verne, G.3    Perlstein, W.M.4    Robinson, M.E.5
  • 38
    • 70350130996 scopus 로고    scopus 로고
    • Direct evidence for spinal cord involvement in placebo analgesia
    • Eippert F, Finsterbusch J, Bingel U, Buchel C: Direct evidence for spinal cord involvement in placebo analgesia. Science 2009; 326: 404.
    • (2009) Science , vol.326 , pp. 404
    • Eippert, F.1    Finsterbusch, J.2    Bingel, U.3    Buchel, C.4
  • 39
    • 3042789578 scopus 로고    scopus 로고
    • State-dependent opioid control of pain
    • Fields H: State-dependent opioid control of pain. Nat Rev Neurosci 2004; 5: 565-575. (Pubitemid 38868552)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.7 , pp. 565-575
    • Fields, H.1
  • 40
    • 20444406792 scopus 로고    scopus 로고
    • Placebo in emotional processing - Induced expectations of anxiety relief activate a generalized modulatory network
    • DOI 10.1016/j.neuron.2005.05.023, PII S0896627305004708
    • Petrovic P, Dietrich T, Fransson P, Andersson J, Carlsson K, Ingvar M: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network. Neuron 2005; 46: 957-969. (Pubitemid 40805354)
    • (2005) Neuron , vol.46 , Issue.6 , pp. 957-969
    • Petrovic, P.1    Dietrich, T.2    Fransson, P.3    Andersson, J.4    Carlsson, K.5    Ingvar, M.6
  • 42
    • 0036356299 scopus 로고    scopus 로고
    • Changes in brain function of depressed subjects during treatment with placebo
    • DOI 10.1176/appi.ajp.159.1.122
    • Leuchter AF, Cook IA, Witte EA, Morgan M, Abrams M: Changes in brain fu nction of depressed subjects during treatment with placebo. Am J Psychiatry 2002; 159:122-129. (Pubitemid 41070737)
    • (2002) American Journal of Psychiatry , vol.159 , Issue.1 , pp. 122-129
    • Leuchter, A.F.1    Cook, I.A.2    Witte, E.A.3    Morgan, M.4    Abrams, M.5
  • 44
    • 68449085750 scopus 로고    scopus 로고
    • Monoamine oxidase and catechol-O-methyltransferase functional polymorphisms and the placebo response in major depressive disorder
    • Leuchter AF, McCracken JT, Hunter AM, Cook IA, Alpert JE: Monoamine oxidase and catechol-O-methyltransferase functional polymorphisms and the placebo response in major depressive disorder. J Clin Psycho-pharmacol 2009; 29: 372-377.
    • (2009) J Clin Psychopharmacol , vol.29 , pp. 372-377
    • Leuchter, A.F.1    McCracken, J.T.2    Hunter, A.M.3    Cook, I.A.4    Alpert, J.E.5
  • 45
    • 0035838997 scopus 로고    scopus 로고
    • Expectation and dopamine release: Mechanism of the placebo effect in Parkinson's disease
    • DOI 10.1126/science.1060937
    • de la Fuente-Fernández R, Ruth TJ, Sossi v, Schulzer M, Calne DB, Stoessl AJ: Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science 2001; 293:1164-1166. (Pubitemid 32758101)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1164-1166
    • De La Fuente-Fernandez, R.1    Ruth, T.J.2    Sossi, V.3    Schulzer, M.4    Calne, D.B.5    Stoessl, A.J.6
  • 47
    • 68149161222 scopus 로고    scopus 로고
    • Electrophysiological properties of thalamic, subthalamic and ni-gral neurons during the anti-parkinsonian placebo response
    • Benedetti F, Lanotte M, Colloca L, Ducati A, Zibetti M, Lopiano L: Electrophysiological properties of thalamic, subthalamic and ni-gral neurons during the anti-parkinsonian placebo response. J Physiol 2009; 587: 3869-3883.
    • (2009) J Physiol , vol.587 , pp. 3869-3883
    • Benedetti, F.1    Lanotte, M.2    Colloca, L.3    Ducati, A.4    Zibetti, M.5    Lopiano, L.6
  • 48
    • 65549106896 scopus 로고    scopus 로고
    • The anatomy of the mesolimbic reward system: A link between personality and the placebo analgesic response
    • Schweinhardt P, Seminowicz DA, Jaeger E, Duncan GH, Bushnell MC: The anatomy of the mesolimbic reward system: a link between personality and the placebo analgesic response. J Neurosci 2009; 29:4882-4887.
    • (2009) J Neurosci , vol.29 , pp. 4882-4887
    • Schweinhardt, P.1    Seminowicz, D.A.2    Jaeger, E.3    Duncan, G.H.4    Bushnell, M.C.5
  • 49
    • 0021723823 scopus 로고
    • Influence of the method of drug administration on analgesic response
    • DOI 10.1038/312755a0
    • Levine JD, Gordon NC: Influence of the method of drug administration on analgesic response. Nature 1984; 312:755-756. (Pubitemid 15195921)
    • (1984) Nature , vol.312 , Issue.5996 , pp. 755-756
    • Levine, J.D.1    Gordon, N.C.2
  • 50
    • 0035864940 scopus 로고    scopus 로고
    • Response variability to analgesics: A role for non-specific activation of endogenous opioids
    • DOI 10.1016/S0304-3959(00)00486-3, PII S0304395900004863
    • Amanzio M, Pollo A, Maggi G, Benedetti F: Response variability to analgesics: a role for non-specific activation of endogenous opioids. Pain 2001; 90:205-215. (Pubitemid 32162942)
    • (2001) Pain , vol.90 , Issue.3 , pp. 205-215
    • Amanzio, M.1    Pollo, A.2    Maggi, G.3    Benedetti, F.4
  • 51
    • 5644272620 scopus 로고    scopus 로고
    • Overt versus covert treatment for pain, anxiety, and Parkinson's disease
    • DOI 10.1016/S1474-4422(04)00908-1, PII S1474442204009081
    • Colloca L, Lopiano L, Lanotte M, Benedetti F: Overt versus covert treatment for pain, anxiety, and Parkinson's disease. Lancet Neurol 2004; 3:679-684. (Pubitemid 39370638)
    • (2004) Lancet Neurology , vol.3 , Issue.11 , pp. 679-684
    • Colloca, L.1    Lopiano, L.2    Lanotte, M.3    Benedetti, F.4
  • 52
    • 0000563503 scopus 로고
    • Drugs and placebos: The effects of instructions upon performance and mood under amphetamine sulphate and chloral hydrate
    • Lyerly SB, Ross S, Krugman AD, Clyde DJ: Drugs and placebos: the effects of instructions upon performance and mood under amphetamine sulphate and chloral hydrate. J Abnorm Psychol 1964; 68:321-327.
    • (1964) J Abnorm Psychol , vol.68 , pp. 321-327
    • Lyerly, S.B.1    Ross, S.2    Krugman, A.D.3    Clyde, D.J.4
  • 53
    • 37049177947 scopus 로고
    • View through a window may influence recovery from surgery
    • Ulrich RS: view through a window may influence recovery from surgery. Science 1984; 224:420-421. (Pubitemid 14134006)
    • (1984) Science , vol.224 , Issue.4647 , pp. 420-421
    • Ulrich, R.S.1
  • 56
    • 70349972975 scopus 로고    scopus 로고
    • Differences in adverse effect reporting in placebo groups in SSRI and tricy-clic antidepressant trials: A systematic review and meta-analysis
    • Rief W, Nestoriuc Y, von Lilienfeld-Toal A, Dogan I, Schreiber F, Hofmann SG, Barsky AJ, Avorn J: Differences in adverse effect reporting in placebo groups in SSRI and tricy-clic antidepressant trials: a systematic review and meta-analysis. Drug Saf 2009; 32:1041-1056.
    • (2009) Drug Saf , vol.32 , pp. 1041-1056
    • Rief, W.1    Nestoriuc, Y.2    Von Lilienfeld-Toal, A.3    Dogan, I.4    Schreiber, F.5    Hofmann, S.G.6    Barsky, A.J.7    Avorn, J.8
  • 57
    • 70350619625 scopus 로고    scopus 로고
    • A systematic review of adverse events in placebo groups of anti-migraine clinical trials
    • Amanzio M, Corazzini LL, vase L, Benedetti F: A systematic review of adverse events in placebo groups of anti-migraine clinical trials. Pain 2009; 146: 261-269.
    • (2009) Pain , vol.146 , pp. 261-269
    • Amanzio, M.1    Corazzini, L.L.2    Vase, L.3    Benedetti, F.4
  • 58
    • 56249138311 scopus 로고    scopus 로고
    • The future of primary care: Transforming practice
    • 2089
    • Bodenheimer T: The future of primary care: transforming practice. N Engl J Med 2008; 359: 2086, 2089.
    • (2008) N Engl J Med , vol.359 , pp. 2086
    • Bodenheimer, T.1
  • 59
    • 73149109054 scopus 로고    scopus 로고
    • Which patients improve: Characteristics increasing sensitivity to a supportive patient-practitioner relationship
    • Conboy LA, Macklin E, Kelley J, Kokkotou E, Lembo A, Kaptchuk T: Which patients improve: characteristics increasing sensitivity to a supportive patient-practitioner relationship. Soc Sci Med 2010; 70:479-484.
    • (2010) Soc Sci Med , vol.70 , pp. 479-484
    • Conboy, L.A.1    Macklin, E.2    Kelley, J.3    Kokkotou, E.4    Lembo, A.5    Kaptchuk, T.6
  • 60
    • 39749142205 scopus 로고    scopus 로고
    • Design makes a difference: A meta-analysis of antidepressant response rates in placebo-controlled versus comparator trials in late-life depression
    • Sneed JR, Rutherford BR, Rindskopf D, Lane DT, Sackeim HA, Roose SP: Design makes a difference: a meta-analysis of antidepressant response rates in placebo-controlled versus comparator trials in late-life depression. Am J Geriatr Psychiatry 2008; 16:65-73.
    • (2008) Am J Geriatr Psychiatry , vol.16 , pp. 65-73
    • Sneed, J.R.1    Rutherford, B.R.2    Rindskopf, D.3    Lane, D.T.4    Sackeim, H.A.5    Roose, S.P.6
  • 62
    • 45549086484 scopus 로고    scopus 로고
    • Experimental designs and brain mapping approaches for studying the placebo analgesic effect
    • Colloca L, Benedetti F, Porro CA: Experimental designs and brain mapping approaches for studying the placebo analgesic effect. Eur J Appl Physiol 2008; 102:371-380.
    • (2008) Eur J Appl Physiol , vol.102 , pp. 371-380
    • Colloca, L.1    Benedetti, F.2    Porro, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.