Cobalt toxicity - an emerging clinical problem in patients with metal-on-metal hip prostheses?

Medical Journal of Australia

Volumn 194, Issue 12, 2011, Pages 649-651

  Mao, Xinzhan ^a   Wong, Andrew A ^b   Crawford, Ross W ^c,d  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^c THE PRINCE CHARLES HOSPITAL   (Australia)

^d QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMIUM; COBALT;

ADULT; AGED; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; DYSPNEA; FEMALE; HIP OSTEOARTHRITIS; HIP PROSTHESIS; HIP RADIOGRAPHY; HUMAN; INTOXICATION; MALE; MUSCLE FATIGUE; NOTE; OSTEOPENIA; REOPERATION; TASTE DISORDER; TOTAL HIP PROSTHESIS; TRACE METAL BLOOD LEVEL;

EID: 79959654056     PISSN: 0025729X     EISSN: 13265377     Source Type: Journal    
DOI: 10.5694/j.1326-5377.2011.tb03151.x     Document Type: Note

References (14)

1. Australian Orthopaedic Association National Joint Replacement Registry. Annual report 2010. Adelaide: AOA, 2010. http://www.dmac.adelaide.edu.au/aoanjrr/documents/aoanjrrreport_2010.pdf (accessed May 2011).
2. Hodgkinson J, Skinner J, Kay P. Updated guidance on large diameter metal on metal bearing total hip replacements. London: British Hip Society, British Orthopaedic Association, National Joint Registry and Medicines and Healthcare products Regulatory Agency, 2011. http:// www.britishhipsociety.com/pdfs/BHS_MOM_THR.pdf (accessed May 2011).
3. Tower SS. Arthroprosthetic cobaltism: neurological and cardiac manifestations in two patients with metal-on-metal arthroplasty: a case report. J Bone Joint Surg Am 2010; 92: 2847-2851.
4. Rizzetti MC, Liberini P, Zarattini G, et al. Loss of sight and sound. Could it be the hip? Lancet 2009; 373: 1052.
5. Brock T, Stopford W. Bioaccessibility of metals in human health risk assessment: evaluating risk from exposure to cobalt compounds. J Environ Monit 2003; 5: 71N-76N.
6. Keegan GM, Learmonth ID, Case CP. Orthopaedic metals and their potential toxicity in the arthroplasty patient: a review of current knowledge and future strategies. J Bone Joint Surg Br 2007; 89: 567-573.
7. Schirrmacher UO. Case of cobalt poisoning. BMJ 1967; 1: 544-545.
8. Queally JM, Devitt BM, Butler JS, et al. Cobalt ions induce chemokine secretion in primary human osteoblasts. J Orthop Res 2009; 27: 855-864.
9. Hart AJ, Hester T, Sinclair K, et al. The association between metal ions from hip resurfacing and reduced T-cell counts. J Bone Joint Surg Br 2006; 88: 449-454.
10. Daou S, El Chemaly A, Christofilopoulos P, et al. The potential role of cobalt ions released from metal prosthesis on the inhibition of Hv1 proton channels and the decrease in Staphylococcus epidermidis killing by human neutrophils. Biomaterials 2011; 32: 1769-1777.
11. Devitt BM, Queally JM, Vioreanu M, et al. Cobalt ions induce chemokine secretion in a variety of systemic cell lines. Acta Orthop 2010; 81: 756-764.
12. Caltana L, Merelli A, Lazarowski A, Brusco A. Neuronal and glial alterations due to focal cortical hypoxia induced by direct cobalt chloride (CoCl2) brain injection. Neurotox Res 2009; 15: 348-358.
13. Engh CA Jr, MacDonald SJ, Sritulanondha S, et al. 2008 John Charnley award: metal ion levels after metal-on-metal total hip arthroplasty: a randomized trial. Clin Orthop Relat Res 2009; 467: 101-111.
14. International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans: volume 86. Cobalt in hard metals and cobalt sulfate, gallium arsenide, indium phosphide and vanadium pentoxide. Lyon: IARC, 2006.