Activation of F-actin binding capacity of ezrin: Synergism of PIP2 interaction and phosphorylation

Biophysical Journal

Volumn 100, Issue 7, 2011, Pages 1708-1717

  Bosk, Sabine ^a   Braunger, Julia A ^a   Gerke, Volker ^b   Steinem, Claudia ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79959645863     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.02.039     Document Type: Article

References (35)

1. Fehon, R. G., A. I. McClatchey, and A. Bretscher. 2010 Organizing the cell cortex: the role of ERM proteins. Nat. Rev. Mol. Cell Biol. 276:276-287.
2. Gary, R., and A. Bretscher. 1995 Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site. Mol. Biol. Cell. 1061:1061-1075.
3. Zhu, L. X., J. Hatakeyama,..., J. G. Forte. 2008 Comparative study of ezrin phosphorylation among different tissues: more is good; too much is bad. Am. J. Physiol. Cell Physiol. 295:C192-C202. (Pubitemid 352755813)
4. Turunen, O., T. Wahlström, and A. Vaheri. 1994 Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family. J. Cell Biol. 1445:1445-1453. (Pubitemid 24284609)
5. Nakamura, F., L. Huang,..., H. Furthmayr. 1999 Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides. Mol. Biol. Cell. 2669:2669-2685. (Pubitemid 29393519)
6. Zhu, L., Y. Liu, and J. G. Forte. 2005 Ezrin oligomers are the membrane-bound dormant form in gastric parietal cells. Am. J. Physiol. Cell Physiol. 288:C1242-C1254. (Pubitemid 40991061)
7. Zhu, L., R. Zhou,..., J. G. Forte. 2007 High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function. Am. J. Physiol. Cell Physiol. 293:C874-C884. (Pubitemid 47437395)
8. Barret, C., C. Roy,..., V. Niggli. 2000 Mutagenesis of the phosphatidylinositol 4, 5-bisphosphate (PIP2) binding site in the NH2-terminal domain of ezrin correlates with its altered cellular distribution. J. Cell Biol. 1067:1067-1080.
9. Niggli, V., C. Andréoli,..., P. Mangeat. 1995 Identification of a phosphatidylinositol-4, 5-bisphosphate-binding domain in the N-terminal region of ezrin. FEBS Lett. 172:172-176.
10. Yonemura, S., T. Matsui,..., S. Tsukita. 2002 Rho-dependent and-independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo. J. Cell Sci. 2569:2569-2580. (Pubitemid 34778074)
11. Rasmussen, M., R. T. Alexander,..., S. F. Pedersen. 2008 Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications. Am. J. Physiol. Cell Physiol. 294:C197-C212.
12. 2 and phosphorylation in moesin activation during Drosophila development. J. Cell Sci. 2058:2058-2067.
13. Fievet, B. T., A. Gautreau,..., M. Arpin. 2004 Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin. J. Cell Biol. 653:653-659. (Pubitemid 38282949)
14. Auvinen, E., N. Kivi, and A. Vaheri. 2007 Regulation of ezrin localization by Rac1 and PIPK in human epithelial cells. Exp. Cell Res. 824:824-833. (Pubitemid 46206076)
15. Hao, J. J., Y. Liu,..., S. Shaw. 2009 Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane. J. Cell Biol. 451:451-462.
16. 2-functionalized lipid bilayers. Biochemistry. 3762:3762-3769. (Pubitemid 351431366)
17. Gautreau, A., D. Louvard, and M. Arpin. 2000 Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane. J. Cell Biol. 193:193-203. (Pubitemid 30480237)
18. Zhou, R., L. Zhu,..., J. G. Forte. 2005 Phosphorylation of ezrin on threonine 567 produces a change in secretory phenotype and repolarizes the gastric parietal cell. J. Cell Sci. 4381:4381-4391. (Pubitemid 41556337)
19. 2+-dependent binding and activation of dormant ezrin by dimeric S100P. Mol. Biol. Cell. 2372:2372-2384. (Pubitemid 36724327)
20. Whitmore, L., and B. A. Wallace. 2004 DICHROWEB, anonline server for protein secondary structure analyses from circular dichroism spectroscopic data. Nucleic Acids Res. 32(Web Server issue):W668-W673. (Pubitemid 38997420)
21. Janshoff, A., H. J. Galla, and C. Steinem. 2000 Piezoelectric masssensing devices as biosensors-an alternative to optical biosensors? Angew. Chem. Int. Ed. Engl. 4004:4004-4032.
22. Pearson, M. A., D. Reczek,..., P. A. Karplus. 2000 Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell. 259:259-270.
23. Steinem, C., and A. Janshoff. 2007 Piezoelectric Sensors. Springer Verlag, Berlin, Germany.
24. 2-containing membranes. Biochemistry. 13025:13025-13034. (Pubitemid 44763425)
25. Behn, D., S. Bosk,..., C. Steinem. 2010 Quantifying the interaction of the C-terminal regions of polycystin-2 and polycystin-1 attached to a lipid bilayer by means of QCM. Biophys. Chem. 47:47-53.
26. 2 and proteins: interactions, organization, and information flow. Annu. Rev. Biophys. Biomol. Struct. 151:151-175.
27. Kremser, L., G. Bilek,..., E. Kenndler. 2007 Capillary electrophoresis of viruses, subviral particles and virus complexes. J. Sep. Sci. 1704:1704-1713. (Pubitemid 47180276)
28. Holmes, K. C., D. Popp,..., W. Kabsch. 1990 Atomic model of the actin filament. Nature. 44:44-49.
29. Matsui, T., M. Maeda,..., S. Tsukita. 1998 Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J. Cell Biol. 647:647-657. (Pubitemid 28134067)
30. Simons, P. C., S. F. Pietromonaco,..., L. Elias. 1998 C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton. Biochem. Biophys. Res. Commun. 561:561-565. (Pubitemid 29039182)
31. Janshoff, A., and C. Steinem. 2001 Quartz crystal microbalance for bioanalytical applications. Sensors Update. 313:313-354.
32. Andréoli, C., M. Martin,..., P. Mangeat. 1994 Ezrin has properties to self-associate at the plasma membrane. J. Cell Sci. 2509:2509-2521. (Pubitemid 24292499)
33. Bretscher, A., R. Gary, and M. Berryman. 1995 Soluble ezrin purified from placenta exists as stable monomers and elongated dimers with masked C-terminal ezrin-radixin-moesin association domains. Biochemistry. 16830:16830-16837. (Pubitemid 26011808)
34. Ceyrolles, W. J., P. Viot, and J. Talbot. 2002 Kinetics of heterogeneous adsorption: mean-field theory and simulations. Langmuir. 1112:1112-1118. (Pubitemid 35384034)
35. Matsui, T., S. Yonemura,..., S. Tsukita. 1999 Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases. Curr. Biol. 1259:1259-1262. (Pubitemid 29527153)