Experimental evidence that methylmalonic acid provokes oxidative damage and compromises antioxidant defenses in nerve terminal and striatum of young rats

Cellular and Molecular Neurobiology

Volumn 31, Issue 5, 2011, Pages 775-785

  Fernandes, Carolina Gonçalves ^a   Borges, Clarissa Günther ^a   Seminotti, Bianca ^a   Amaral, Alexandre Umpierrez ^a   Knebel, Lisiane Aurélio ^a   Eichler, Paula ^a   De Oliveira, Anderson Büker ^a,b   Leipnitz, Guilhian ^a   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Brain synaptosomes; Methylmalonic acid; Methylmalonic acidemia; Oxidative stress; Propionic acid; Propionic acidemia; Striatum

Indexed keywords

ALPHA TOCOPHEROL; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIZOCILPINE; GLUTATHIONE PEROXIDASE; MELATONIN; METHYLMALONIC ACID; PROPIONIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN SYNAPTOSOME; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; LIPID OXIDATION; LIPID PEROXIDATION; MALE; NERVE ENDING; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; FLUORESCEINS; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; METHYLMALONIC ACID; NEOSTRIATUM; NERVE ENDINGS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SYNAPTOSOMES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 79959606454     PISSN: 02724340     EISSN: 15736830     Source Type: Journal    
DOI: 10.1007/s10571-011-9675-4     Document Type: Article

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