Systemic signature of the lung response to respiratory syncytial virus infection

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Pennings, Jeroen L A ^a   Schuurhof, Annemieke ^a,b   Hodemaekers, Hennie M ^a   Buisman, Annemarie ^a   de Rond, Lia C G H ^a   Widjojoatmodjo, Myra N ^c   Luytjes, Willem ^c   Kimpen, Jan L L ^b   Bont, Louis ^b   Janssen, Riny ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NETHERLANDS VACCINE INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; CXCL9 CHEMOKINE; GRANZYME A; GRANZYME B; IMMUNOGLOBULIN G1; NEUTROPHIL COLLAGENASE; OCTAMER TRANSCRIPTION FACTOR 2; RIBONUCLEASE; SONIC HEDGEHOG PROTEIN; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR GATA 3; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CONTROLLED STUDY; EOSINOPHIL; GENE EXPRESSION; IMMUNE RESPONSE; INFLAMMATION; LUNG FUNCTION; LYMPH NODE; MOUSE; NATURAL KILLER CELL; NONHUMAN; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SECONDARY INFECTION; SIGNAL TRANSDUCTION; TH1 CELL; UPREGULATION; VIRAL BRONCHIOLITIS; ANIMAL; BAGG ALBINO MOUSE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PHYSIOLOGY; VACCINATION; VIROLOGY;

MURINAE; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

ANIMALS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LUNG; LYMPH NODES; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; VACCINATION;

EID: 79959585798     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021461     Document Type: Article

References (30)

1. Hall CB, Weinberg GA, Iwane MK, Blumkin AK, Edwards KM, et al. (2009) The burden of respiratory syncytial virus infection in young children. N Engl J Med 360: 588-598.
2. McNamara PS, Smyth RL, (2002) The pathogenesis of respiratory syncytial virus disease in childhood. Br Med Bull 61: 13-28.
3. Simoes EA, Carbonell-Estrany X, (2003) Impact of severe disease caused by respiratory syncytial virus in children living in developed countries. Pediatr Infect Dis J 22: S13-18.
4. Bloemers BL, van Furth AM, Weijerman ME, Gemke RJ, Broers CJ, et al. (2007) Down syndrome: a novel risk factor for respiratory syncytial virus bronchiolitis--a prospective birth-cohort study. Pediatrics 120: e1076-1081.
5. Meissner HC, (2003) Selected populations at increased risk from respiratory syncytial virus infection. Pediatr Infect Dis J 22: S40-44.
6. Janssen R, Pennings J, Hodemaekers H, Buisman A, van Oosten M, et al. (2007) Host transcription profiles upon primary respiratory syncytial virus infection. J Virol 81: 5958-5967.
7. Schuurhof A, Bont L, Pennings JL, Hodemaekers HM, Wester PW, et al. (2010) Gene expression differences in lungs of mice during secondary immune responses to respiratory syncytial virus infection. J Virol 84: 9584-9594.
8. Fjaerli HO, Bukholm G, Krog A, Skjaeret C, Holden M, et al. (2006) Whole blood gene expression in infants with respiratory syncytial virus bronchiolitis. BMC Infect Dis 6: 175.
9. Zaas AK, Chen M, Varkey J, Veldman T, Hero AO III, et al. (2009) Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans. Cell Host Microbe 6: 207-217.
10. Ramilo O, Allman W, Chung W, Mejias A, Ardura M, et al. (2007) Gene expression patterns in blood leukocytes discriminate patients with acute infections. Blood 109: 2066-2077.
11. Thach DC, Agan BK, Olsen C, Diao J, Lin B, et al. (2005) Surveillance of transcriptomes in basic military trainees with normal, febrile respiratory illness, and convalescent phenotypes. Genes Immun 6: 588-595.
12. Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, et al. (2010) An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466: 973-977.
13. Huang DW, Sherman BT, Tan Q, Kir J, Liu D, et al. (2007) DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res 35: W169-W175.
14. Wu C, Orozco C, Boyer J, Leglise M, Goodale J, et al. (2009) BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol 10: R130.
15. Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, et al. (2008) Expression analysis of G Protein-Coupled Receptors in mouse macrophages. ImmunomeRes 4: 5.
16. Pennings JL, Kimman TG, Janssen R, (2008) Identification of a common gene expression response in different lung inflammatory diseases in rodents and macaques. PLoS One 3: e2596.
17. Chaussabel D, Quinn C, Shen J, Patel P, Glaser C, et al. (2008) A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus. Immunity 29: 150-164.
18. Palmer C, Diehn M, Alizadeh AA, Brown PO, (2006) Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC Genomics 7: 115.
19. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102: 15545-15550.
20. Jelier R, Schuemie MJ, Veldhoven A, Dorssers LC, Jenster G, et al. (2008) Anni 2.0: a multipurpose text-mining tool for the life sciences. Genome Biol 9: R96.
21. Rubins KH, Hensley LE, Jahrling PB, Whitney AR, Geisbert TW, et al. (2004) The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model. Proc Natl Acad Sci U S A 101: 15190-15195.
22. Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, et al. (2007) Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. J Infect Dis 196: 826-834.
23. Kumar S, Mitnik C, Valente G, Floyd-Smith G, (2000) Expansion and molecular evolution of the interferon-induced 2′-5′ oligoadenylate synthetase gene family. Mol Biol Evol 17: 738-750.
24. Katsoulidis E, Carayol N, Woodard J, Konieczna I, Majchrzak-Kita B, et al. (2009) Role of Schlafen 2 (SLFN2) in the generation of interferon alpha-induced growth inhibitory responses. J Biol Chem 284: 25051-25064.
25. Ho Sui SJ, Mortimer JR, Arenillas DJ, Brumm J, Walsh CJ, et al. (2005) oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes. Nucleic Acids Res 33: 3154-3164.
26. Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, et al. (2008) Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. PLoS One 3: e1912.
27. Allantaz F, Chaussabel D, Stichweh D, Bennett L, Allman W, et al. (2007) Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade. J Exp Med 204: 2131-2144.
28. Dressman HK, Muramoto GG, Chao NJ, Meadows S, Marshall D, et al. (2007) Gene expression signatures that predict radiation exposure in mice and humans. PLoS Med 4: e106.
29. Rosenberg HF, (2008) RNase A ribonucleases and host defense: an evolving story. J Leukoc Biol 83: 1079-1087.
30. Rosenberg HF, Domachowske JB, (2001) Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens. J Leukoc Biol 70: 691-698.