Aeromonas spp. induce apoptosis of epithelial cells through an oxidant-dependent activation of the mitochondrial pathway

Journal of Medical Microbiology

Volumn 60, Issue 7, 2011, Pages 889-898

  Krzymińska, Sylwia ^a   Tańska, Anna ^a   Kaznowski, Adam ^a  

^a ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CASPASE; ENTEROTOXIN; GENOMIC DNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE;

AEROMONAS; AEROMONAS HYDROPHILA; AEROMONAS PUNCTATA; AEROMONAS SOBRIA; AEROMONAS VERONII; APOPTOSIS; ARTICLE; BACTERIAL GENE; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM DETECTION; BACTERIUM ISOLATE; BIOTYPE; CELL STRAIN HT29; CELL STRUCTURE; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME ACTIVATION; EPITHELIUM CELL; ESCHERICHIA COLI; FECES CULTURE; GASTROENTERITIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INCUBATION TIME; INTRACELLULAR SIGNALING; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AEROMONAS; APOPTOSIS; EPITHELIAL CELLS; GASTROENTERITIS; GRAM-NEGATIVE BACTERIAL INFECTIONS; HT29 CELLS; HUMANS; INTESTINAL MUCOSA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NITRIC OXIDE; OXIDANTS; REACTIVE OXYGEN SPECIES; VIRULENCE;

EID: 79959522654     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.030833-0     Document Type: Article

References (31)

1. 2+ uptake in cystic fibrosis airway epithelial cells. Mitochondrion 9, 232-241.
2. Bauer, G. (2002). Signaling and proapoptotic functions of transformed cell-derived reactive oxygen species. Prostaglandins Leukot Essent Fatty Acids 66, 41-56.
3. Circu, M. L. & Aw, T. Y. (2010). Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med 48, 749-762.
4. Curtin, J. F., Donovan, M. & Cotter, T. G. (2002). Regulation and measurement of oxidative stress in apoptosis. J Immunol Methods 265, 49-72.
5. Ding, S. Z., Minohara, Y., Fan, X. J., Wang, J., Reyes, V. E., Patel, J., Dirden-Kramer, B., Boldogh, I., Ernst, P. B. & Crowe, S. E. (2007). Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells. Infect Immun 75, 4030-4039.
6. Dockrell, D. H. (2001). Apoptotic cell death in the pathogenesis of infectious diseases. J Infect 42, 227-234.
7. Falcón, R. M., Carvalho, H. F., Joazeiro, P. P., Viccari Gatti, M. S. & Yano, T. (2001). Induction of apoptosis in HT29 human intestinal epithelial cells by the cytotoxic enterotoxin of Aeromonas hydrophila. Biochem Cell Biol 79, 525-531.
8. Figueras, M. J., Soler, L., Chacón, M. R., Guarro, J. & Martínez-Murcia, A. J. (2000). Extended method for discrimination of Aeromonas spp. by 16S rDNA RFLP analysis. Int J Syst Evol Microbiol 50, 2069-2073.
9. Galindo, C. L., Fadl, A. A., Sha, J., Gutierrez, C., Jr, Popov, V. L., Boldogh, I., Aggarwal, B. B. & Chopra, A. K. (2004). Aeromonas hydrophila cytotoxic enterotoxin activates mitogen-activated protein kinases and induces apoptosis in murine macrophages and human intestinal epithelial cells. J Biol Chem 279, 37597-37612.
10. Galindo, C. L., Sha, J., Fadl, A. A., Pillai, L. L. & Chopra, A. K. (2006). Host immune responses to Aeromonas virulence factors. Curr Immunol Rev 2, 13-26.
11. Galluzzi, L., Zamzami, N., de La Motte Rouge, T., Lemaire, C., Brenner, C. & Kroemer, G. (2007). Methods for the assessment of mitochondrial membrane permeabilization in apoptosis. Apoptosis 12, 803-813.
12. Guimarães, M. S., Andrade, J. R. C., Freitas-Almeida, A. C. & Ferreira, M. C. S. (2002). Aeromonas hydrophila vacuolating activity in the Caco-2 human enterocyte cell line as a putative virulence factor. FEMS Microbiol Lett 207, 127-131.
13. Janda, J. M. & Abbott, S. L. (2010). The genus Aeromonas: taxonomy, pathogenicity, and infection. Clin Microbiol Rev 23, 35-73.
14. Ježek, P. & Hlavatá, L. (2005). Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int J Biochem Cell Biol 37, 2478-2503.
15. Kannan, S., Suresh Kanna, P., Karkuzhali, K., Chattopadhyay, U. K. & Pal, D. (2001). Direct detection of diarrheagenic Aeromonas from faeces by polymerase chain reaction (PCR) targeting aerolysin toxin gene. Eur Rev Med Pharmacol Sci 5, 91-94.
16. Kim, P. K. M., Zamora, R., Petrosko, P. & Billiar, T. R. (2001). The regulatory role of nitric oxide in apoptosis. Int Immunopharmacol 1, 1421-1441.
17. Kingombe, C. I. B., Huys, G., Tonolla, M., Albert, M. J., Swings, J., Peduzzi, R. & Jemmi, T. (1999). PCR detection, characterization, and distribution of virulence genes in Aeromonas spp. Appl Environ Microbiol 65, 5293-5302.
18. Krzymińska, S., Kaznowski, A., Lindner, K. & Mnichowska, M. (2003). Enteropathogenic activity and invasion of HEp-2 cells by Aeromonas caviae clinical isolates. Acta Microbiol Pol 52, 277-283.
19. Krzymińska, S., Kaznowski, A. & Spychała, H. (2006). Purification and characterization of cytolytic toxins produced by Aeromonas hydrophila and Aeromonas veronii biotype sobria strains. Pol J Microbiol 55, 37-42.
20. Krzymińska, S., Kaznowski, A. & Chodysz, M. (2009a). Aeromonas spp. human isolates induce apoptosis of murine macrophages. Curr Microbiol 58, 252-257.
21. Krzymińska, S., Mokracka, J., Koczura, R. & Kaznowski, A. (2009b). Cytotoxic activity of Enterobacter cloacae human isolates. FEMS Immunol Med Microbiol 56, 248-252.
22. Niki, E. (2009). Lipid peroxidation: physiological levels and dual biological effects. Free Radic Biol Med 47, 469-484.
23. Nilsson, B. O. (1999). Biological effects of aminoguanidine: an update. Inflamm Res 48, 509-515.
24. Pitcher, D. G., Saunders, N. A. & Owen, R. J. (1989). Rapid extraction of bacterial genomic DNA with guanidium thiocyanate. Lett Appl Microbiol 8, 151-156.
25. Rinaldi, M., Moroni, P., Paape, M. J. & Bannerman, D. D. (2007). Evaluation of assays for the measurement of bovine neutrophil reactive oxygen species. Vet Immunol Immunopathol 115, 107-125.
26. Rudel, T., Kepp, O. & Kozjak-Pavlovic, V. (2010). Interactions between bacterial pathogens and mitochondrial cell death pathways. Nat Rev Microbiol 8, 693-705.
27. Superti, F., Pietrantoni, A., Di Biase, A. M., Longhi, C., Valenti, P. & Tinari, A. (2005). Inv-mediated apoptosis of epithelial cells infected with enteropathogenic Yersinia: a protective effect of lactoferrin. Res Microbiol 156, 728-737.
28. Szczuka, E. & Kaznowski, A. (2004). Typing of clinical and environmental Aeromonas sp. strains by random amplified polymorphic DNA PCR, repetitive extragenic palindromic PCR, and enterobacterial repetitive intergenic consensus sequence PCR. J Clin Microbiol 42, 220-228.
29. Tsai, Y. H., Hsu, R. W., Huang, T. J., Hsu, W. H., Huang, K. C., Li, Y. Y. & Peng, K. T. (2007). Necrotizing soft-tissue infections and sepsis caused by Vibrio vulnificus compared with those caused by Aeromonas species. J Bone Joint Surg Am 89, 631-636.
30. von Graevenitz, A. (2007). The role of Aeromonas in diarrhea: a review. Infection 35, 59-64.
31. Wang, G., Tyler, K. D., Munro, C. K. & Johnson, W. M. (1996). Characterization of cytotoxic, hemolytic Aeromonas caviae clinical isolates and their identification by determining presence of a unique hemolysin gene. J Clin Microbiol 34, 3203-3205.