Reduced circulating endothelial progenitor cell number in healthy young adult hyperinsulinemic men

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 21, Issue 7, 2011, Pages 512-517

  Dei Cas, A ^a   Spigoni, V ^a   Ardigo D ^a   Pedrazzi, G ^a   Franzini, L ^a   Derlindati, E ^a   Urbani, S ^b   Monti, L ^c   Gnudi, L ^d   Zavaroni, I ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Endothelial progenitor cells; Gender; Insulin resistance

Indexed keywords

BIOLOGICAL MARKER; CD133 ANTIGEN; CD34 ANTIGEN; GLYCOPROTEIN; LEUKOCYTE ANTIGEN; PEPTIDE; VASCULOTROPIN RECEPTOR 2;

ADULT; ARTICLE; BLOOD; CARDIOVASCULAR DISEASE; CELL COUNT; CROSS-SECTIONAL STUDY; CYTOLOGY; ENDOTHELIUM CELL; FEMALE; HUMAN; HYPERINSULINISM; INSULIN RESISTANCE; ITALY; MALE; METABOLISM; PATHOPHYSIOLOGY; SEX DIFFERENCE; STEM CELL;

ADULT; ANTIGENS, CD; ANTIGENS, CD34; BIOLOGICAL MARKERS; CARDIOVASCULAR DISEASES; CELL COUNT; CROSS-SECTIONAL STUDIES; ENDOTHELIAL CELLS; FEMALE; GLYCOPROTEINS; HUMANS; HYPERINSULINISM; INSULIN RESISTANCE; ITALY; MALE; PEPTIDES; SEX FACTORS; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 79959493990     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2009.11.011     Document Type: Article

References (25)

1. Asahara T., Murohara T., Sullivan A., Silver M., van der Z.R., Li T., et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997, 275:964-967.
2. Crosby J.R., Kaminski W.E., Schatteman G., Martin P.J., Raines E.W., Seifert R.A., et al. Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation. Circ Res 2000, 87:728-730.
3. Fadini G.P., de Kreutzenberg S., Albiero M., Coracina A., Pagnin E., Baesso I., et al. Gender differences in endothelial progenitor cells and cardiovascular risk profile: the role of female estrogens. Arterioscler Thromb Vasc Biol 2008, 28:997-1004.
4. Vasa M., Fichtlscherer S., Aicher A., Adler K., Urbich C., Martin H., et al. Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease. Circ Res 2001, 89:E1-E7.
5. Hill J.M., Zalos G., Halcox J.P., Schenke W.H., Waclawiw M.A., Quyyumi A.A., et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 2003, 348:593-600.
6. Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988, 37:1595-1607.
7. Zavaroni I., Bonini L., Gasparini P., Barilli A.L., Zuccarelli A., Dall'Aglio E., et al. Hyperinsulinemia in a normal population as a predictor of non-insulin-dependent diabetes mellitus, hypertension, and coronary heart disease: the Barilla factory revisited. Metabolism 1999, 48:989-994.
8. Tepper O.M., Galiano R.D., Capla J.M., Kalka C., Gagne P.J., Jacobowitz G.R., et al. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 2002, 106:2781-2786.
9. Loomans C.J., de Koning E.J., Staal F.J., Rookmaaker M.B., Verseyden C., de Boer H.C., et al. Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes. Diabetes 2004, 53:195-199.
10. Fadini G.P., de Kreutzenberg S.V., Coracina A., Baesso I., Agostini C., Tiengo A., et al. Circulating CD34+ cells, metabolic syndrome, and cardiovascular risk. Eur Heart J 2006, 27:2247-2255.
11. Akhter J. The American diabetes Association's clinical practice recommendations and the developing world. Diabetes Care 1997, 20:1044-1045.
12. Ferrannini E., Natali A., Bell P., Cavallo-Perin P., Lalic N., Mingrone G. Insulin resistance and hypersecretion in obesity. European group for the study of insulin resistance (EGIR). J Clin Invest 1997, 100:1166-1173.
13. Gupta A.K., Jain S.K. A study to evaluate surrogate markers of insulin resistance in forty euglycemic healthy subjects. J Assoc Physicians India 2004, 52:549-553.
14. Yeni-Komshian H., Carantoni M., Abbasi F., Reaven G.M. Relationship between several surrogate estimates of insulin resistance and quantification of insulin-mediated glucose disposal in 490 healthy nondiabetic volunteers. Diabetes Care 2000, 23:171-175.
15. Fadini G.P., Baesso I., Albiero M., Sartore S., Agostini C., Avogaro A. Technical notes on endothelial progenitor cells: ways to escape from the knowledge plateau. Atherosclerosis 2008, 197:496-503.
16. Urbich C., Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Circ Res 2004, 95:343-353.
17. Sibal L., Aldibbiat A., Agarwal S.C., Mitchell G., Oates C., Razvi S., et al. Circulating endothelial progenitor cells, endothelial function, carotid intima-media thickness and circulating markers of endothelial dysfunction in people with type 1 diabetes without macrovascular disease or microalbuminuria. Diabetologia 2009.
18. Bulut D., Albrecht N., Imohl M., Gunesdogan B., Bulut-Streich N., Borgel J., et al. Hormonal status modulates circulating endothelial progenitor cells. Clin Res Cardiol 2007, 96:258-263.
19. Hoetzer G.L., MacEneaney O.J., Irmiger H.M., Keith R., Van Guilder G.P., Stauffer B.L., et al. Gender differences in circulating endothelial progenitor cell colony-forming capacity and migratory activity in middle-aged adults. Am J Cardiol 2007, 99:46-48.
20. Ciulla M.M., Giorgetti A., Silvestris I., Cortiana M., Montelatici E., Paliotti R., et al. Endothelial colony forming capacity is related to C-reactive protein levels in healthy subjects. Curr Neurovasc Res 2006, 3:99-106.
21. Strehlow K., Werner N., Berweiler J., Link A., Dirnagl U., Priller J., et al. Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation. Circulation 2003, 107:3059-3065.
22. Lemieux C., Cloutier I., Tanguay J.F. Menstrual cycle influences endothelial progenitor cell regulation: a link to gender differences in vascular protection?. Int J Cardiol 2008.
23. Fadini G.P., Pucci L., Vanacore R., Baesso I., Penno G., Balbarini A., et al. Glucose tolerance is negatively associated with circulating progenitor cell levels. Diabetologia 2007, 50:2156-2163.
24. Kuki S., Imanishi T., Kobayashi K., Matsuo Y., Obana M., Akasaka T. Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase. Circ J 2006, 70:1076-1081.
25. Segal M.S., Shah R., Afzal A., Perrault C.M., Chang K., Schuler A., et al. Nitric oxide cytoskeletal-induced alterations reverse the endothelial progenitor cell migratory defect associated with diabetes. Diabetes 2006, 55:102-109.