A novel class 1 integron array carrying blaVIM-2 genes and a new insertion sequence in a Pseudomonas aeruginosa strain isolated from a Spanish hospital

Journal of Medical Microbiology

Volumn 60, Issue 7, 2011, Pages 1053-1054

  Rojo Bezares, Beatriz ^a   Estepa, Vanesa ^b   de Toro, María ^a,b   Undabeitia, Esther ^c   Olarte, Inés ^c   Torres, Carmen ^a,b   Sáenz, Yolanda ^a  

^a CENTER FOR BIOMEDICAL RESEARCH OF LA RIOJA CIBIR   (Spain)

^b UNIVERSITY OF LA RIOJA   (Spain)

^c HOSPITAL SAN PEDRO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AZTREONAM; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; MEROPENEM; SULFONAMIDE; TICARCILLIN; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; GENE INSERTION SEQUENCE; INTEGRON; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

BETA-LACTAMASES; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTEGRONS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SPAIN;

EID: 79959491450     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.030973-0     Document Type: Article

References (16)

1. Bonomo, R. A. & Szabo, D. (2006). Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa. Clin Infect Dis 43 (Suppl. 2), S49-S56.
2. CLSI (2010). Performance Standards for Antimicrobial Susceptibility Testing, 20th International Supplement M100-S20. Wayne, PA: Clinical and Laboratory Standards Institute.
3. Curran, B., Jonas, D., Grundmann, H., Pitt, T. & Dowson, C. G. (2004). Development of a multilocus sequence typing scheme for the opportunistic pathogen Pseudomonas aeruginosa. J Clin Microbiol 42, 5644-5649.
4. Ellington, M. J., Kistler, J., Livermore, D. M. & Woodford, N. (2007). Multiplex PCR for rapid detection of genes encoding acquired metallobeta-lactamases. J Antimicrob Chemother 59, 321-322.
5. SHV2a carriage in isolates of a persistent, multidrug-resistant Pseudomonas aeruginosa clone from Tunis. Clin Microbiol Infect 16, 189-193.
6. Jové, T., Da Re, S., Denis, F., Mazel, D. & Ploy, M. C. (2010). Inverse correlation between promoter strength and excision activity in class 1 integrons. PLoS Genet 6, e1000793.
7. Kaufmann, M. E. (1998). Pulsed-field gel electrophoresis. Methods Mol Med 15, 33-50.
8. Lambert, T., Ploy, M. C. & Courvalin, P. (1994). A spontaneous point mutation in the aac(69)-Ib9 gene results in altered substrate specificity of aminoglycoside 69-N-acetyltransferase of a Pseudomonas fluorescens strain. FEMS Microbiol Lett 115, 297-304.
9. Lee, K., Chong, Y., Shin, H. B., Kim, Y. A., Yong, D. & Yum, J. H. (2001). Modified Hodge and EDTAdisk synergy tests to screen metallo-betalactamase-producing strains of Pseudomonas and Acinetobacter species. Clin Microbiol Infect 7, 88-91.
10. Mahillon, J. & Chandler, M. (1998). Insertion sequences. Microbiol Mol Biol Rev 62, 725-774.
11. Nemec, A., Krizova, L., Maixnerova, M. & Musilek, M. (2010). Multidrug-resistant epidemic clones among bloodstream isolates of Pseudomonas aeruginosa in the Czech Republic. Res Microbiol 161, 234-242.
12. Partridge, S. R., Tsafnat, G., Coiera, E. & Iredell, J. R. (2009). Gene cassettes and cassette arrays in mobile resistance integrons. FEMS Microbiol Rev 33, 757-784.
13. Sáenz, Y., Briñas, L., Domínguez, E., Ruiz, J., Zarazaga, M., Vila, J. & Torres, C. (2004). Mechanisms of resistance in multiple-antibioticresistant Escherichia coli strains of human, animal, and food origins. Antimicrob Agents Chemother 48, 3996-4001.
14. Samuelsen, Ø., Toleman, M. A., Sundsfjord, A., Rydberg, J., Leegaard, T. M., Walder, M., Lia, A., Ranheim, T. E., Rajendra, Y. & other authors (2010). Molecular epidemiology of metallobeta-lactamase-producing Pseudomonas aeruginosa isolates from Norway and Sweden shows import of international clones and local clonal expansion. Antimicrob Agents Chemother 54, 346-352.
15. VIM-2 in a Pseudomonas putida strain from Portugal. Clin Microbiol Infect 16, 1558-1561.
16. Walsh, T. R., Toleman, M. A., Poirel, L. & Nordmann, P. (2005). Metallo-beta-lactamases: the quiet before the storm? Clin Microbiol Rev 18, 306-325.