Mechanistic insight into polysaccharide use within the intestinal microbiota

Gut Microbes

Volumn 2, Issue 2, 2011, Pages

  Bolam, David N ^a   Sonnenburg, Justin L ^b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bacteroidetes; Dietary polysaccharides; Fructan; Germ free mice; Hybrid two component system; Intestinal microbiota; Polysaccharide utilization locus

Indexed keywords

BINDING PROTEIN; FRUCTAN; FRUCTOSE; GENE PRODUCT; GLYCOSIDASE; POLYSACCHARIDE; STARCH;

ADAPTIVE BEHAVIOR; ARTICLE; BACTERIAL GENE; BACTEROIDES THETAIOTAOMICRON; BACTEROIDETES; CARBOHYDRATE INTAKE; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; GENE LOCUS; GLYCOLYSIS; INTESTINE FLORA; NONHUMAN; POLYSACCHARIDE UTILIZATION LOCUS; PREVOTELLA; TWO HYBRID SYSTEM; BIOLOGICAL MODEL; ENZYMOLOGY; GASTROINTESTINAL TRACT; HUMAN; METABOLISM; MICROBIOLOGY; REVIEW;

BACTEROIDETES; MUS;

BACTEROIDETES; GASTROINTESTINAL TRACT; HUMANS; MODELS, BIOLOGICAL; POLYSACCHARIDES;

EID: 79959459193     PISSN: 19490976     EISSN: 19490984     Source Type: Journal    
DOI: 10.4161/gmic.2.2.15232     Document Type: Article

References (17)

1. Sonnenburg ED, Zheng H, Joglekar P, Higginbottom SK, Firbank SJ, Bolam DN, et al. Specificity of polysaccharide use in intestinal Bacteroides species determines diet-induced microbiota alterations. Cell 2010; 141:1241-52.
2. Reeves AR, Wang GR, Salyers AA. Characterization of four outer membrane proteins that play a role in utilization of starch by Bacteroides thetaiotaomicron. J Bacteriol 1997; 179:643-9.
3. Shipman JA, Berleman JE, Salyers AA. Characterization of four outer membrane proteins involved in binding starch to the cell surface of Bacteroides thetaiotaomicron. J Bacteriol 2000; 182:5365-72.
4. Martens EC, Koropatkin NM, Smith TJ, Gordon JI. Complex glycan catabolism by the human gut microbiota: The Bacteroidetes Sus-like paradigm. J Biol Chem 2009; 284:24673-7
5. Koropatkin NM, Martens EC, Gordon JI, Smith TJ. Starch catabolism by a prominent human gut symbi-ont is directed by the recognition of amylose helices. Structure 2008; 16:1105-15.
6. Flint HJ, Bayer EA, Rincon MT, Lamed R, White BA. Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis. Nat Rev Microbiol 2008; 6:121-31.
7. Martens EC, Chiang HC, Gordon JI. Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe 2008; 4:447-57
8. Koropatkin NM, Smith TJ. SusG: A unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules. Structure 2010; 18:200-15.
9. Hehemann JH, Correc G, Barbeyron T, Helbert W, Czjzek M, Michel G. Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota. Nature 2010; 464:908-12.
10. Jung WS, Hong CK, Lee S, Kim CS, Kim SJ, Kim SI, et al. Structural and functional insights into intramolecular fructosyl transfer by inulin fructotransferase. J Biol Chem 2007; 282:8414-23.
11. Roberfroid MB. Introducing inulin-type fructans. Br J Nutr 2005; 93:13-25.
12. Kitamura M, Okuyama M, Tanzawa F, Mori H, Kitago Y, Watanabe N, et al. Structural and functional analysis of a glycoside hydrolase family 97 enzyme from Bacteroides thetaiotaomicron. J Biol Chem 2008; 283:36328-37
13. van den Ende W, Clerens S, Vergauwen R, van Riet L, van Laere A, Yoshida M, et al. Fructan 1-exohydrolases. beta-(2,1)-trimmers during grami-nan biosynthesis in stems of wheat? Purification, characterization, mass mapping and cloning of two fructan 1-exo hydrolase isoforms. Plant Physiol 2003; 131:621-31.
14. Cho KH, Salyers AA. Biochemical analysis of interactions between outer membrane proteins that contribute to starch utilization by Bacteroides thetaiotaomicron. J Bacteriol 2001; 183:7224-30.
15. Menke M, Berger B, Cowen L. Markov random fields reveal an N-terminal double beta-propeller motif as part of a bacterial hybrid two-component sensor system. Proc Natl Acad Sci USA 2010; 107:4069-74.
16. Mascher T, Helmann J D, Unden G. Stimulus perception in bacterial signal-transducing histidine kinases. Microbiol Mol Biol Rev 2006; 70:910-38.
17. Miyazaki K, Hirase T, Kojima Y, Flint HJ. Medium-to large-sized xylo-oligosaccharides are responsible for xylanase induction in Prevotella bryantii B14. Microbiology (Reading, England) 2005; 151:4121-5.