Oxytocin may be useful to increase trust in others and decrease disruptive behaviours in patients with Prader-Willi syndrome: A randomised placebo-controlled trial in 24 patients

Orphanet Journal of Rare Diseases

Volumn 6, Issue 1, 2011, Pages

  Tauber, Mathe ^a,b,c   Mantoulan, Carine ^a   Copet, Pierre ^d   Jauregui, Joseba ^d   Demeer, Genevieve ^d   Diene, Gwenalle ^a   Rogé, Bernadette ^e   Laurier, Virginie ^d   Ehlinger, Virginie ^f   Arnaud, Catherine ^f   Molinas, Catherine ^a,b,c   Thuilleaux, Denise ^d  

^a HÔPITAL DES ENFANTS   (France)

^b INSERM   (France)

^c France   (France)

^d Hôpital Marin d'Hendaye   (France)

^e Université de Toulouse II Le Mirail   (France)

^f TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTOCIN; PLACEBO;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; BEHAVIOR CHANGE; CLINICAL ARTICLE; CONFLICT; CONTROLLED STUDY; DISRUPTIVE BEHAVIOR; DOUBLE BLIND PROCEDURE; FEMALE; HOSPITAL ADMISSION; HUMAN; MALE; PATIENT; PRACTICE GUIDELINE; PRADER WILLI SYNDROME; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SOCIAL ADAPTATION; TRUST; ADOLESCENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; PSYCHOLOGICAL ASPECT;

ADOLESCENT; ADULT; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; OXYTOCIN; PLACEBOS; PRADER-WILLI SYNDROME; YOUNG ADULT;

EID: 79959455590     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/1750-1172-6-47     Document Type: Article

References (21)

1. Prader-Willi syndrome. SB Cassidy, J Med Genet 1997 34 917 923 10.1136/jmg.34.11.917 9391886 (Pubitemid 27480947)
2. Recommendations for the diagnosis and management of Prader-Willi syndrome. AP Goldstone AJ Holland BP Hauffa AC Hokken-Koelega M Tauber, J Clin Endocrinol Metab 2008 93 4183 4197 10.1210/jc.2008-0649 18697869 (Pubitemid 352789509)
3. Prader-Willi syndrome, compulsive and ritualistic behaviours: the first population-based survey. DJ Clarke H Boer J Whittington A Holland J Butler T Webb, Br J Psychiatry 2002 180 358 362 10.1192/bjp.180.4.358 11925360 (Pubitemid 34407324)
4. Autistic-like symptomatology in Prader-Willi syndrome: a review of recent findings. A Dimitropoulos RT Schultz, Curr Psychiatry Rep 2007 9 159 164 10.1007/s11920-007-0086-7 17389128 (Pubitemid 46579154)
5. Deficits in social attribution ability in Prader-Willi syndrome. K Koenig A Klin R Schultz, J Autism Dev Disord 2004 34 573 582 10.1007/s10803-004-2551-z 15628610 (Pubitemid 40941083)
6. Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases. DF Swaab JS Purba MA Hofman, J Clin Endocrinol Metab 1995 80 573 579 10.1210/jc.80.2.573 7852523
7. Oxytocin, vasopressin, and the neurogenetics of sociality. ZR Donaldson LJ Young, Science 2008 322 900 904 10.1126/science.1158668 18988842
8. Oxytocin improves "mind-reading" in humans. G Domes M Heinrichs A Michel C Berger SC Herpertz, Biol Psychiatry 2007 61 731 733 10.1016/j.biopsych.2006.07.015 17137561
9. Effects of intranasal oxytocin on emotional face processing in women. G Domes A Lischke C Berger A Grossmann K Hauenstein M Heinrichs SC Herpertz, Psychoneuroendocrinology 2010 35 83 93 10.1016/j.psyneuen.2009.06.016 19632787
10. Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict. B Ditzen M Schaer B Gabriel G Bodenmann U Ehlert M Heinrichs, Biol Psychiatry 2009 65 728 731 10.1016/j.biopsych.2008.10.011 19027101
11. Oxytocin increases gaze to the eye region of human faces. AJ Guastella PB Mitchell MR Dadds, Biol Psychiatry 2008 63 3 5 10.1016/j.biopsych.2007.06.026 17888410 (Pubitemid 350234895)
12. Intranasal Oxytocin Improves Emotion Recognition for Youth with Autism Spectrum Disorders. AJ Guastella SL Einfeld KM Gray NJ Rinehart BJ Tonge TJ Lambert IB Hickie, Biol Psychiatry 2010 67 692 4 10.1016/j.biopsych.2009.09.020 19897177
13. Oxytocin increases retention of social cognition in autism. E Hollander J Bartz W Chaplin A Phillips J Sumner L Soorya E Anagnostou S Wasserman, Biol Psychiatry 2007 61 498 503 10.1016/j.biopsych.2006.05.030 16904652 (Pubitemid 46185336)
14. Oxytocin improves specific recognition of positive facial expressions. AA Marsh HH Yu DS Pine RJ Blair, Psychopharmacology 2010 209 3 225 32 10.1007/s00213-010-1780-4 20186397
15. Understanding other minds: Perpectives from developmental neuroscience. S Baron-Cohen H Tager-Flusberg D Cohen eds, Oxford: Oxford University Press 2 2000
16. N Eisenberg F Fabes, Prosocial development Handbook of Child Psychology: Social, Emotional, and Personality Development Wiley, New York 646 718
17. Cognitive profile in a large French cohort of adults with Prader-Willi syndrome: differences between genotypes. P Copet J Jauregi V Laurier V Ehlinger C Arnaud AM Cobo C Molinas M Tauber D Thuilleaux, J Intellect Disabil Res 2010 54 204 215 10.1111/j.1365-2788.2010.01251.x 20136683
18. A neuropsychological assessment of frontal cognitive functions in Prader-Willi syndrome. J Jauregi C Arias O Vegas F Alen S Martinez P Copet D Thuilleaux, J Intellect Disabil Res 2007 51 350 365 10.1111/j.1365-2788.2006. 00883.x 17391252 (Pubitemid 46502069)
19. Does the autistic child have a "theory of mind"? S Baron-Cohen AM Leslie U Frith, Cognition 1985 21 37 46 10.1016/0010-0277(85)90022-8 2934210
20. The "Reading the Mind in the Eyes" Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. S Baron-Cohen S Wheelwright J Hill Y Raste I Plumb, J Child Psychol Psychiatry 2001 42 241 251 10.1111/1469-7610.00715 11280420 (Pubitemid 32233124)
21. PET scan perfusion imaging in the Prader-Willi syndrome: new insights into the psychiatric and social disturbances. C Mantoulan P Payoux G Diene M Glattard B Roge C Molinas A Sevely M Zilbovicius P Celsis M Tauber, J Cereb Blood Flow Metab 2011 31 275 82 10.1038/jcbfm.2010.87 20588317