From risk factor assessment to cardiovascular disease risk and mortality modification: The first 40 years of the Brisighella Heart Study

Clinical Lipidology

Volumn 6, Issue 3, 2011, Pages 269-276

  Cicero, Arrigo Fg ^a   Dormi, Ada ^a   D'addato, Sergio ^a   Borghi, Claudio ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Brisighella Heart Study; cardiovascular disease epidemiology; risk factor

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; COLESTYRAMINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ESTRONE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; GHRELIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PRASTERONE; SIMVASTATIN; TESTOSTERONE; TRIACYLGLYCEROL;

ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; DIET THERAPY; HEALTH SURVEY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; INCIDENCE; ITALY; METABOLIC SYNDROME X; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUTRITION EDUCATION; OBSERVATIONAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT;

EID: 79959424654     PISSN: 17460875     EISSN: 17584302     Source Type: Journal    
DOI: 10.2217/clp.11.23     Document Type: Review

References (40)

1. Muchiteni T, Borden WB: Improving risk factor modification: a global approach. Curr. Cardiol. Rep. 11(6), 476-483 (2009).
2. Vanuzzo D, Pilotto L, Uguccioni M et al.: Cardiovascular epidemiology: trends of risk factors in Italy. Ital. Heart J. 5(Suppl. 8), S19-S27 (2004).
3. Volpato S, Vigna GB, McDermott MM et al.: Lipoprotein(a), inflammation, and peripheral arterial disease in a community-based sample of older men and women (the InCHIANTI study). Am. J. Cardiol. 105(12), 1825-1830 (2010).
4. Noto D, Barbagallo CM, Cefalù AB et al.: The metabolic syndrome predicts cardiovascular events in subjects with normal fasting glucose: results of a 15 years follow-up in a Mediterranean population. Atherosclerosis 197(1), 147-153 (2008). (Pubitemid 351278405)
5. Tsimikas S, Willeit J, Knoflach M et al.: Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study. Eur. Heart J. 30(1), 107-115 (2009).
6. Ferrara LA, Cardoni O, Mancini M, Zanchetti A: Metabolic syndrome and left ventricular hypertrophy in a general population. Results from the Gubbio Study. J. Hum. Hypertens. 21(10), 795-801 (2007). (Pubitemid 47450005)
7. Descovich GC, Cavallo G, Mannino G, Lenzi S: The Brisighella survey: a study of dietary habits. Minerva Med. 74(11), 547-555 (1983). (Pubitemid 13128030)
8. Attili AF, Carulli N, Roda E et al.: Epidemiology of gallstone disease in Italy: prevalence data of the Multicenter Italian Study on Cholelithiasis (M.I.COL.). Am. J. Epidemiol. 141(2), 158-165 (1995).
9. ERICA Project Stuff: The CHD risk map of Europe. The 1st report of the WHO-ERICA Project. Eur. Heart J. 9, 1-35 (1988).
10. Seccareccia F, Lanti M, Menotti A, Scanga M: Role of body mass index in the prediction of all cause mortality in over 62,000 men and women. The Italian RIFLE Pooling Project. Risk Factor and Life Expectancy. J. Epidemiol. Community Health 52(1), 20-26 (1988).
11. Menotti A, Lanti M, Puddu PE et al.: The risk functions incorporated in Riscard 2002: a software for the prediction of cardiovascular risk in the general population based on Italian data. Ital. Heart J. 3(2), 114-121 (2002). (Pubitemid 34591554)
12. Menotti A, Lanti M, Agabiti-Rosei E et al.: Riskard 2005. New tools for prediction of cardiovascular disease risk derived from Italian population studies. Nutr. Metab. Cardiovasc. Dis. 15(6), 426-440 (2005). (Pubitemid 43986478)
13. Ardigò D, Bernini F, Borghi C et al.; on behalf of the ADSL Project Investigators: advanced diagnostic support in lipidology project: role for phenotypic and functional evaluation of lipoproteins in dyslipidemias. Clin. Lipidol. 5(3), 329-337 (2010).
14. Descovich GC, Aluigi L, Benassi MS et al.: The Brisighella investigation. Results of the observational study 1972-1980. Minerva Cardioangiol. 33(9), 565-574 (1985). (Pubitemid 16243706)
15. Descovich GC: The Brisighella Heart Study: an interim report. Eur. Heart J. 11, S32-S37 (1990).
16. Sangiorgi Z, Pignatelli S, Pascarelli N et al.: The "Brisighella Terme" Project: effectiveness of preventive medicine in thermal ambient. Hematochemical parameters. Eur. Rev. Med. Pharmacol. Sci. 2(3-4), 151-156 (1998). (Pubitemid 29453102)
17. Nascetti S, Falasca P, Mengolini B, Cicero AFG, Linarello S, Gaddi A; Brisighella Heart Study Working Party: Health profile of a population as a predictor of health resources utilization: results of the implementation of an epidemiologic model for needs analysis. Epidemiol. Prev. 27(5), 269-276 (2003).
18. Borghi C, Cicero AFG: Hypertension and hypercholesterolemia: from theory to cardiovascular disease risk prevention. Hot Topics Cardiol. 12, 1-28 (2008).
19. Strehlow K, Wassmann S, Bohm M, Nickenig G: Angiotensin AT1 receptor over-expression in hypercholesterolaemia. Ann. Med. 32(6), 386-389 (2000).
20. Nickenig G, Bohm M: Regulation of the angiotensin AT1 receptor expression by hypercholesterolemia. Eur. J. Med. Res. 2(7), 285-289 (1997).
21. Borghi C, Dormi A, Cicero AFG, Cosentino ER, D'Addato S, Viozzi P: Effects of age on the relationship between lipid profile and blood pressure in the Brisighella Heart Study. J. Hypertens. 27(4), S113 (2009).
22. Bonaa KH, Thelle DS: Association between blood pressure and serum lipids in a population. The Tromso Study. Circulation 83(4), 1305-1314 (1991).
23. Ruixing Y, Jinzhen W, Weixiong L, Yuming C, Dezhai Y, Shangling P: The environmental and genetic evidence for the association of hyperlipidemia and hypertension. J. Hypertens. 27(2), 251-258 (2009).
24. Borghi C, Dormi A, Gaddi A, Ambrosioni E: Relationship between serum cholesterol and development of hypertension in the population of the Brisighella Heart Study. Am. J. Hypertens. 16(5), A207 (2003).
25. Halperin RO, Sesso HD, Ma J, Buring JE, Stampfer MJ, Gaziano JM: Dyslipidemia and the risk of incident hypertension in men. Hypertension 47(1), 45-50 (2006). (Pubitemid 43177814)
26. Sesso HD, Buring JE, Chown MJ, Ridker PM, Gaziano JM: A prospective study of plasma lipid levels and hypertension in women. Arch. Intern. Med. 165(20), 2420-2427 (2005). (Pubitemid 41640856)
27. Borghi C, Cicero AFG, Cardella G et al.: Changes in levels of serum cholesterol and development of hypertension in the Brisighella Heart Study. J. Hypertens. 28, e406 (2010).
28. Borghi C, Dormi A, Veronesi M, Sangiorgi Z, Gaddi A; Brisighella Heart Study Working Party: Association between different lipid-lowering treatment strategies and blood pressure control in the Brisighella Heart Study. Am. Heart J. 148(2), 285-292 (2004). (Pubitemid 39092793)
29. Committee of Principal Investigators: A co-operative trial in the primary prevention of ischemic heart disease using clofibrate. Br. Heart J. 40, 1069-1118 (1978).
30. Ekelund LG: Lowering lipids and the genesis of hypertension. Drugs 36(Suppl. 3), 21 (1988).
31. Borghi C, Dormi A, Ambrosioni E, Gaddi A; Brisighella Heart Study Working Party: Relative role of systolic, diastolic and pulse pressure as risk factors for cardiovascular events in the Brisighella Heart Study. J. Hypertens. 20(9), 1737-1742 (2002).
32. Borghi C, Dormi A, L'Italien G et al.: The relationship between systolic blood pressure and cardiovascular risk -results of the Brisighella Heart Study. J. Clin. Hypertens. 5(1),47-52 (2003). (Pubitemid 36221560)
33. Cicero AF, Dormi A, Nascetti S et al.: Relative role of major risk factors for Type 2 diabetes development in the historical cohort of the Brisighella Heart Study: an 8-year follow-up. Diabet. Med. 22(9), 1263-1266 (2005). (Pubitemid 41224190)
34. Cicero AF, Manca M, Bove M, Dormi A, Borghi C, Gaddi AV; Brisighella Heart Study group: Detection of familial combined hyperlipoproteinaemia patients in the Brisighella Heart Study historical cohort: an epidemiological approach. J. Inherit. Metab. Dis. 30(2), 268 (2007).
35. Gaddi A, Cicero AFG, Dormi A, Pasquarelli V, D'Addato S: The realisation of a project aimed at reducing the plasmatic lipid level in a large Italian rural population improves the mean calcium daily intake: the Brisighella Study (BS). Eur. J. Clin. Nutr. 55(2), 97-106 (2001) (Pubitemid 32156889)
36. Cicero AF, Dormi A, D'Addato S, Gaddi AV, Borghi C: Long-term effect of a dietary education program on postmenopausal cardiovascular risk and metabolic syndrome: the Brisighella Heart Study. J. Womens Health 19(1), 133-137 (2010)
37. Dormi A, Cicero AFG, Favali D, Mascitti M, Toma M, Gaddi A: Cardiovascular mortality and risk factor trends in a large rural population: the Brisighella Heart Study. Atherosclerosis 144(S1), 140 (1999).
38. Borghi C, Dormi A, D'Addato S, Gaddi A, Ambrosioni E; Brisighella Heart Study Working Party: Trends in blood pressure control and antihypertensive treatment in clinical practice: the Brisighella Heart Study. J. Hypertens. 22(9), 1707-1716 (2004) (Pubitemid 39141962)
39. Mueller JC, Lõhmussaar E, Mägi R et al.: Linkage disequilibrium patterns and tagSNP transferability among European populations. Am. J. Hum. Genet. 76(3), 387-398 (2005). (Pubitemid 40250519)
40. Cicero AF, Magni P, Lentini P et al.; Brisighella Heart Study Staff: Sex hormones and adipokines in healthy pre-menopausal, post-menopausal and elderly women, and in age-matched men: data from the Brisighella Heart Study. J. Endocrinol. Invest. (2010) (Epub ahead of print).