Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants

Neonatology

Volumn 100, Issue 3, 2011, Pages 290-294

  Mansi, Yasmeen ^a   Abdelaziz, Nabil ^a   Ezzeldin, Zahraa ^a   Ibrahim, Rania ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Gastric residuals; Gastrointestinal dysmotility; Necrotizing enterocolitis; Preterm

Indexed keywords

ERYTHROMYCIN ETHYLSUCCINATE;

ARTICLE; ARTIFICIAL MILK; ARTIFICIAL VENTILATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MEGADOSE; ENTERIC FEEDING; FEMALE; GESTATIONAL AGE; HEART ARRHYTHMIA; HUMAN; INFANT; LOOSE FECES; MALE; MORTALITY; NECROTIZING ENTEROCOLITIS; NEWBORN; NUTRITIONAL ASSESSMENT; NUTRITIONAL INTOLERANCE; OBSTRUCTIVE JAUNDICE; PATIENT MONITORING; PREMATURITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SEPSIS; WEIGHT GAIN;

DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ENTERAL NUTRITION; ERYTHROMYCIN; FEMALE; GASTROINTESTINAL AGENTS; GASTROINTESTINAL DISEASES; GASTROINTESTINAL MOTILITY; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; MALE; PROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; WEIGHT GAIN;

EID: 79959387351     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000327536     Document Type: Article

References (25)

1. Thureen P, Reynolds R: Special circumstances: trophic feeds, NEC, and BPD. Semin Fetal Neonatal Med 2007;12:64-70.
2. Ng PC: Use of oral erythromycin for the treatment of gastrointestinal dysmotility in preterm infants. Neonatology 2009;95:97-104.
3. Kaufman SS, Gondolesi GE, Fishbein TM: Parentral nutrition associated liver disease. Semin Neonatol 2003;8:375-381. (Pubitemid 37237133)
4. Lander A, Redkar R, Nicholls G, et al: Cisapride reduces neonatal postoperative ileus: randomised placebo controlled trial. Arch Dis Child 1997;77:119-122.
5. Curry JI, Lander TD, Stringer MD: Erythromycin as aprokinetic agent in infants and children. Aliment Pharmacol Ther 2001;15:595-603. (Pubitemid 32385863)
6. Costalos C, Gounaris A, Varhalama E, Kokori F, Alexiou N, Kolovou E: Erythromycin as aprokinetic agent in preterm infants. J Pediatr Gastroenterol Nutr 2002;34:23-25. (Pubitemid 34251696)
7. Nuntnarumit P, Kiatchoosakun P, Tantiprapa W, Boonkasidecha S: Efficacy of oral erythromycin for treatment of feeding in tolerance in preterm infants. J Pediatr 2006;148:600-605. (Pubitemid 43776898)
8. Aly H, Abdel-Hady H, Khashaba M, El- Badry N:Erythromycin and feeding in tolerance in preterm infants: a randomized controlled trial. J Perinatol 2007;27:39-43. (Pubitemid 44971051)
9. Ng PC, Gomez JM, Rajadurai VS, Saw S, Quak S: Establishing enteral feeding inpreterm infants with feeding intolerance; a randomized controlled trial of low dose erythromycin. J Pediatr Gastroentrol Nutr 2003;37:554-558. (Pubitemid 39280860)
10. Ng PC, So KW, Fung KS, Lee CH, Fok TF, Wong E, et al: Randomised controlled study of oral erythromycin for treatment of gastro-intestinal dysmotility in preterm infants. Arch Dis Child Fetal Neonatal Ed 2001;84:F177-F182. (Pubitemid 32411256)
11. Ng PC, Lee CH, Wong SP, Lam HS, Liu FYB, So KW, Lee CY, Fok TF: High dose oral erythromycin decreased the incidence of parentral nutrition-associated cholestasis in preterm infants. Gastroenterology 2007;132:1726-1739. (Pubitemid 46677952)
12. Cairns PA, Craig S, Tubman R, Roberts RS, Wilson J, Schmidt B: Randomised controlled trial of low dose erythromycin in preterm infants with feed in tolerance. Pediatr Res 2002;51:379A.
13. El Hennawy AA, Sparks J W, Armentrout D, Huseby V, Berseth CL: Erythromycin fails to improve feeding outcome in feeding intolerant preterm infants. J Pediatr Gastroentrol Nutr 2003;37:281-286. (Pubitemid 39274518)
14. Madani A, Pishva N, Pourarian Sh, Zarkesh M: The efficacy of oral erythromycin in enhancement of milk tolerance in premature infants. A randomized controlled trial. Iran J Med Sci 2004;29:1-4. (Pubitemid 39421905)
15. Oei J, Lui K: A placebo-controlled trial of low-dose erythromycin to promote feed tolerance in preterm infants. Acta Paediatr 2001;90:904-908 (Pubitemid 32762838)
16. Jadcherla SR, Klee G, Berseth CL: Regulation ofmigrating motor complexes by motilin and pancreatic peptide in human infants. Pediatr Res 1997;42:365-369. (Pubitemid 27362734)
17. Coulie B, Tack J, Peeters T, Janssen J: Involvement oftwo different pathways in the motor effects of erythromycin on the gastric antrum in humans. Gut 1998;43:395-400. (Pubitemid 28414922)
18. Varanness BD, Parys V, Ropert A, Chayvialle JA, Roze C, Galmiche JP: Erythromycin enhances fasting and postprandial proximal gastric tone in humans. Gastroenterology 1995;109:32-39.
19. Annese V, Janssens J, Vantrappen G, Tack J, Peeters TL, Willemse P, Van Cutsem E: Erythromycin accelerates gastric emptying by inducing antral contractions and improved gastroduodenal coordination. Gastroenterology 1992:102:823-828.
20. Tack J,Vantrappen G, Peeters T, Annese V, Depoortere I, Muls E, Janssens J, Bouillon R: Effect of erythromycin on gastric motility in controls and in diabetic gastroparesis. Gastroenterology 1992;103:72-79.
21. Bisset WM, Watt J B, Rivers PA, Milla PJ: Ontogeny of fasting small intestinal motor activity in the human infant. Gut 1998;29:483-488.
22. Berseth CL: Gestational evolution of small intestinal motility in preterm and term infa nts. J Pediatr 1989;115:646-651.
23. Vantrappen GR, Janssens J, Peeters TL, Bioom SR, Christofides ND, Hellemans J: Motilin and the interdigestive motor complex in man. Dig Dis Sci 1979;24:497-500. (Pubitemid 9236877)
24. Tomomasa T, Tabata M, Nako Y, Kaneko H, Morikawa A: The effect of oral erythromycin on gastric emptying in neonates with gastric retention. Gastroenterology 1997;112(suppl):A839.
25. Jadcherla SR, Berseth CL: Effect of erythromycin on gastroduodenal contractile activity in developing neonates. J Pediatr Gastroenterol Nutr 2002;34:16-22. (Pubitemid 34251695)