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Wang L, Ge Z, Luo J, et al. HIV transmission risk among serodiscordant couples: a retrospective study of former plasma donors in Henan, China. J Acquir Immune Defic Syndr 2010; 55:232-238. This article reports findings from a prospective study of 1927 serodiscordant couples. Authors report an HIV incidence rate of 1.71 per 100 person-years in which transmission events are equally distributed among couples whose index case was receiving or was not receiving ART.
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Using mathematical models to analyze HIV surveillance data in British Columbia, the authors of this study claimed evidence of strong population-level associations among expanded ART coverage, decreased population viral load, and fewer annual HIV diagnoses between 1996 and 2009
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Montaner JS, Lima VD, Barrios R, et al. Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study. Lancet 2010; 376:532-539. Using mathematical models to analyze HIV surveillance data in British Columbia, the authors of this study claimed evidence of strong population-level associations among expanded ART coverage, decreased population viral load, and fewer annual HIV diagnoses between 1996 and 2009.
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·] on the association between ART coverage and community HIV viral load. Safer injection practices among IDUs is also highlighted as a likely confounder that could lead to overestimation of the association between expanded ART on lowered HIV incidence in British Columbia
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·] on the association between ART coverage and community HIV viral load. Safer injection practices among IDUs is also highlighted as a likely confounder that could lead to overestimation of the association between expanded ART on lowered HIV incidence in British Columbia.
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Jin F, Jansson J, Law M. Per-contact probability of HIV transmission in homosexual men in Sydney during the era of HAART. AIDS 2010; 24:907-913. A longitudinal cohort study of homosexual men in Australia found little difference in the per-contact probability of HIV transmission before and after widespread uptake of ART in HIV-infected men. The authors hypothesize that untreated STIs or unprotected sex during acute infection may partially explain the persistence of transmission even with high ART coverage.
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DOI 10.1097/01.qai.0000155037.10628.cb
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Hightow LB, MacDonald PD, Pilcher CD, et al. The unexpected movement of the HIV epidemic in the southeastern United States: transmission among college students. J Acquir Immune Defic Syndr 2005; 38:531-537. (Pubitemid 40524474)
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