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Volumn 879, Issue 21, 2011, Pages 1967-1972
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An HPLC method for the pharmacokinetic study of vincristine sulfate-loaded PLGA-PEG nanoparticle formulations after injection to rats
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Author keywords
HPLC; Nanoparticle; Pharmacokinetics; PLGA PEG; Vincristine
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Indexed keywords
AVERAGE METHOD;
CALIBRATION CURVES;
CHROMATOGRAPHIC SEPARATIONS;
CONCENTRATION RANGES;
DIHYDROGEN;
EXTRACTION RECOVERY;
FREEZE-THAW CYCLES;
HPLC;
HPLC METHOD;
INTERNAL STANDARDS;
INTRAVENOUS INJECTIONS;
MOBILE PHASE;
NANOPARTICLE FORMULATION;
PHARMACOKINETIC PARAMETERS;
PHARMACOKINETIC PROFILES;
PHARMACOKINETIC STUDIES;
PHYSIOLOGICAL SALINE;
PLGA-PEG;
POLY(LACTIC-CO-GLYCOLIC ACID);
RAT PLASMA;
ROOM TEMPERATURE;
ULTRA VIOLET DETECTION;
VINBLASTINE;
VINCRISTINE;
VINCRISTINE SULFATE;
BODY FLUIDS;
ETHYLENE;
GLYCOLS;
METHANOL;
MOTION PICTURE EXPERTS GROUP STANDARDS;
NANOPARTICLES;
PHARMACOKINETICS;
PLASMAS;
POLYETHYLENE GLYCOLS;
RATS;
SODIUM;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
FOLIC ACID;
MACROGOL;
METHANOL;
NANOPARTICLE;
POLYGLACTIN;
SODIUM DIHYDROGEN PHOSPHATE;
VINBLASTINE SULFATE;
VINCRISTINE SULFATE;
ACCURACY;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
CHROMATOGRAPHY;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG CLEARANCE;
DRUG FORMULATION;
DRUG HALF LIFE;
DRUG STABILITY;
DRUG STRUCTURE;
FLOW RATE;
FREEZE THAWING;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
MAXIMUM PLASMA CONCENTRATION;
NONHUMAN;
PRIORITY JOURNAL;
QUALITY CONTROL;
RAT;
ROOM TEMPERATURE;
ANALYSIS OF VARIANCE;
ANIMALS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG DELIVERY SYSTEMS;
DRUG STABILITY;
HUMANS;
INJECTIONS, INTRAVENOUS;
LINEAR MODELS;
NANOPARTICLES;
POLYETHYLENE GLYCOLS;
POLYGLACTIN 910;
RATS;
RATS, SPRAGUE-DAWLEY;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
VINCRISTINE;
RATTUS;
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EID: 79959365801
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2011.05.031 Document Type: Article |
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Times cited : (27)
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References (24)
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