Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 21, 2011, Pages 1911-1916

  Rao, R Nageswara ^a   Kumar, K Nagesh ^a   Ramakrishna, S ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Antidepressants; Enantiomeric separation; Metabolite; Mirtazapine; Reverse polar ionic LC; Vancomycin

Indexed keywords

ANTIDEPRESSANTS; ENANTIOMERIC SEPARATION; MIRTAZAPINE; REVERSE POLAR IONIC LC; VANCOMYCIN;

ACETIC ACID; BIOMOLECULES; BODY FLUIDS; CHIRALITY; DETECTORS; ENANTIOMERS; FLUORESCENCE; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIC LIQUIDS; METABOLISM; METABOLITES; METHANOL; OPTICAL ROTATION; POLARIMETERS; POLAROGRAPHIC ANALYSIS; RATS;

CHROMATOGRAPHY;

ACETIC ACID; DRUG METABOLITE; METHANOL; MIRTAZAPINE; N DESMETHYL MIRTAZAPINE; TRIETHYLAMINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL EXPERIMENT; ARTICLE; ENANTIOMER; EXTRACTION; FLUORESCENCE; LIQUID CHROMATOGRAPHY; NONHUMAN; OPTICAL ROTATION; POLARIMETER; PRECIPITATION; PRIORITY JOURNAL; RAT; VALIDATION PROCESS;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; LINEAR MODELS; MIANSERIN; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE; STEREOISOMERISM;

RATTUS;

EID: 79959352698     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.05.017     Document Type: Article

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