-
1
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
-
10.1016/S0140-6736(11)60613-2 published online June 4. on behalf of the MRC COIN Trial Investigators C.G.
-
TS Maughan, RA Adams, CG Smith on behalf of the MRC COIN Trial Investigators Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial Lancet 2011 10.1016/S0140-6736(11)60613-2 published online June 4.
-
(2011)
Lancet
-
-
Maughan, T.S.1
Adams, R.A.2
Smith3
-
3
-
-
79959349114
-
EXPERT-C: A randomized phase II European multicenter trial of neoadjuvant chemotherapy (capecitabine/oxaliplatin) and chemoradiation (CRT) with or without cetuximab followed by total mesorectal excision (TME) in patients with MRI-defined high-risk rectal cancer
-
A Dewdney, D Cunningham, J Tabernero et al. EXPERT-C: a randomized phase II European multicenter trial of neoadjuvant chemotherapy (capecitabine/ oxaliplatin) and chemoradiation (CRT) with or without cetuximab followed by total mesorectal excision (TME) in patients with MRI-defined high-risk rectal cancer J Clin Oncol 29 suppl 4 2011 360 (abstr).
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL. 4
, pp. 360
-
-
Dewdney, A.1
Cunningham, D.2
Tabernero, J.3
-
4
-
-
69549095959
-
Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines
-
L Dahan, A Sadok, JL Formento, JF Seitz, H Kovacic Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines Br J Pharmacol 158 2009 610 620
-
(2009)
Br J Pharmacol
, vol.158
, pp. 610-620
-
-
Dahan, L.1
Sadok, A.2
Formento, J.L.3
Seitz, J.F.4
Kovacic, H.5
-
5
-
-
79956298812
-
Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
-
E Van Cutsem, CH Kohne, I Lang et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status J Clin Oncol 29 2011 2011 2019
-
(2011)
J Clin Oncol
, vol.29
, pp. 2011-2019
-
-
Van Cutsem, E.1
Kohne, C.H.2
Lang, I.3
-
7
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
-
De Roock W Claes B. * Bernasconi D. et al.
-
De Roock W B Claes, D Bernasconi et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis Lancet Oncol 11 2010 753 762
-
(2010)
Lancet Oncol
, vol.11
, pp. 753-762
-
-
-
8
-
-
78049341541
-
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
-
W De Roock, DJ Jonker, F Di Nicolantonio et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab JAMA 304 2010 1812 1820
-
(2010)
JAMA
, vol.304
, pp. 1812-1820
-
-
De Roock, W.1
Jonker, D.J.2
Di Nicolantonio, F.3
-
9
-
-
78049443211
-
Relationship between colorectal cancer biomarkers and response to epidermal growth factor receptor monoclonal antibodies
-
E Hawkes, D Cunningham Relationship between colorectal cancer biomarkers and response to epidermal growth factor receptor monoclonal antibodies J Clin Oncol 28 2010 e529 e531
-
(2010)
J Clin Oncol
, vol.28
-
-
Hawkes, E.1
Cunningham, D.2
-
10
-
-
65349149003
-
TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy
-
A Oden-Gangloff, F Di Fiore, F Bibeau et al. TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy Br J Cancer 100 2009 1330 1335
-
(2009)
Br J Cancer
, vol.100
, pp. 1330-1335
-
-
Oden-Gangloff, A.1
Di Fiore, F.2
Bibeau, F.3
-
11
-
-
79957599577
-
Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients
-
M Scartozzi, I Bearzi, A Mandolesi et al. Epidermal growth factor receptor (EGFR) gene promoter methylation and cetuximab treatment in colorectal cancer patients Br J Cancer 104 2011 1786 1790
-
(2011)
Br J Cancer
, vol.104
, pp. 1786-1790
-
-
Scartozzi, M.1
Bearzi, I.2
Mandolesi, A.3
-
12
-
-
79959367361
-
Beyond KRAS mutation status: Influence of KRAS copy number alteration and microRNAs in response to cetuximab in metastatic colorectal cancer patients
-
April 2-6 (abstr)
-
Mekenkamp L, Tol J, Dijkstra J, et al. Beyond KRAS mutation status: influence of KRAS copy number alteration and microRNAs in response to cetuximab in metastatic colorectal cancer patients. AACR Annual Meeting, Orlando, Florida; April 2-6, 2011; 235 (abstr).
-
(2011)
AACR Annual Meeting, Orlando, Florida
, pp. 235
-
-
Mekenkamp, L.1
Tol, J.2
Dijkstra, J.3
-
13
-
-
77953276067
-
Correlation of FCGR3A and EGFR germline polymorphisms with the efficacy of cetuximab in KRAS wild-type metastatic colorectal cancer
-
J Pander, H Gelderblom, NF Antonini et al. Correlation of FCGR3A and EGFR germline polymorphisms with the efficacy of cetuximab in KRAS wild-type metastatic colorectal cancer Eur J Cancer 46 2010 1829 1834
-
(2010)
Eur J Cancer
, vol.46
, pp. 1829-1834
-
-
Pander, J.1
Gelderblom, H.2
Antonini, N.F.3
-
14
-
-
79959571031
-
Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
-
10.1016/S1470-2045(11)70102-4 published online June 4. on behalf of the MRC COIN Trial Investigators M.T.
-
RA Adams, AM Meade, MT Seymour on behalf of the MRC COIN Trial Investigators Intermittent versus continuous oxaliplatin and fluoropyrimidine combination chemotherapy for first-line treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial Lancet Oncol 2011 10.1016/S1470-2045(11)70102-4 published online June 4.
-
(2011)
Lancet Oncol
-
-
Adams, R.A.1
Meade, A.M.2
Seymour3
-
15
-
-
73349089651
-
Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? the GERCOR OPTIMOX2 Study
-
B Chibaudel, F Maindrault-Goebel, G Lledo et al. Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 Study J Clin Oncol 27 2009 5727 5733
-
(2009)
J Clin Oncol
, vol.27
, pp. 5727-5733
-
-
Chibaudel, B.1
Maindrault-Goebel, F.2
Lledo, G.3
|