Atomic force microscopy of Connexin40 gap junction hemichannels reveals calcium-dependent three-dimensional molecular topography and open-closed conformations of both the extracellular and cytoplasmic faces

Journal of Biological Chemistry

Volumn 286, Issue 25, 2011, Pages 22139-22146

  Allen, Michael J ^a   Gemel, Joanna ^a   Beyer, Eric C ^a   Lal, Ratnesh ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BI-LAYER; C-TERMINAL TAIL; CHANNEL ENTRANCES; CONFORMATIONAL CHANGE; CYTOPLASMIC DOMAINS; DIVALENT CATION; EXTRACELLULAR; GAP JUNCTIONS; HEMICHANNELS; HIGH RESOLUTION; MOLECULAR TOPOGRAPHY; PHOSPHATIDYLCHOLINE; REALTIME IMAGING; THREE-DIMENSIONAL TOPOGRAPHY; TOPOGRAPHIC INFORMATION;

ATOMIC FORCE MICROSCOPY; CALCIUM; LIPID BILAYERS; THREE DIMENSIONAL;

TOPOGRAPHY;

CALCIUM ION; CONNEXIN 40; DIOLEOYLPHOSPHATIDYLCHOLINE; DIVALENT CATION; EDETIC ACID;

ARTICLE; ATOMIC FORCE MICROSCOPY; CHANNEL GATING; CONFORMATIONAL TRANSITION; CYTOPLASM; EXTRACELLULAR SPACE; HELA CELL; LIPID BILAYER; MEMBRANE STRUCTURE; PRIORITY JOURNAL;

ANIMALS; BUFFERS; CALCIUM; CONNEXINS; CYTOPLASM; EXTRACELLULAR SPACE; GAP JUNCTIONS; HELA CELLS; HUMANS; LIPID BILAYERS; MICROSCOPY, ATOMIC FORCE; PROTEIN CONFORMATION; RATS;

EID: 79959332086     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.240002     Document Type: Article

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