Analyte and internal standard cross signal contributions and their impact on quantitation in LC-MS based bioanalysis

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 21, 2011, Pages 1954-1960

  Tan, Aimin ^a   Lévesque, Isabelle A ^a   Lévesque, Isabelle M ^a   Viel, François ^a   Boudreau, Nadine ^a   Lévesque, Ann ^a  

^a PharmaNet Canada   (Canada)

Author keywords

Bioanalysis; Cross contribution; LC MS; Mass spectrometry; Quantitation; Reference standard purity; Tiagabine

Indexed keywords

BIOANALYSIS; CROSS-CONTRIBUTION; LC-MS; QUANTITATION; REFERENCE STANDARD; TIAGABINE;

CALIBRATION; ERRORS; IMPURITIES; MASS SPECTROMETRY; QUALITY CONTROL; SYSTEMATIC ERRORS;

STANDARDS;

EDETIC ACID; TIAGABINE;

ARTICLE; CALIBRATION; CHEMICAL STRUCTURE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUALITY CONTROL; SIMULATION; STANDARD; SYSTEMATIC ERROR; VALIDITY;

CHROMATOGRAPHY, LIQUID; COMPUTER SIMULATION; HUMANS; LEAST-SQUARES ANALYSIS; MASS SPECTROMETRY; NIPECOTIC ACIDS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 79959330280     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.05.027     Document Type: Article

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