Extranodal extension in node-positive bladder cancer: The continuing controversy

BJU International

Volumn 108, Issue 1, 2011, Pages 38-43

  Jeong, In Gab ^a   Ro, Jae Y ^b,c   Kim, Seong Cheol ^a   You, Dalsan ^a   Song, Cheryn ^a   Hong, Jun Hyuk ^a   Ahn, Hanjong ^a   Kim, Choung Soo ^a  

^a Asan Medical Center   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

lymph nodes; neoplasm metastasis; prognosis; urinary bladder neoplasms

Indexed keywords

ADULT; AGED; ARTICLE; BLADDER CANCER; CANCER DIAGNOSIS; CANCER INVASION; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; CYSTECTOMY; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; EVIDENCE BASED MEDICINE; FEMALE; HISTOPATHOLOGY; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; SURVIVAL RATE; SURVIVAL TIME; TRANSITIONAL CELL CARCINOMA; TUMOR VOLUME;

ADULT; AGED; ANALYSIS OF VARIANCE; CYSTECTOMY; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; URINARY BLADDER NEOPLASMS;

EID: 79959323873     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2010.09823.x     Document Type: Article

References (20)

1. Stein JP, Lieskovsky G, Cote R, et al,. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001; 19: 666-75 (Pubitemid 32120143)
2. Kassouf W, Agarwal PK, Herr HW, et al,. Lymph node density is superior to TNM nodal status in predicting disease-specific survival after radical cystectomy for bladder cancer: analysis of pooled data from MDACC and MSKCC. J Clin Oncol 2008; 26: 121-6
3. Stein JP, Cai J, Groshen S, Skinner DG,. Risk factors for patients with pelvic lymph node metastases following radical cystectomy with en bloc pelvic lymphadenectomy: concept of lymph node density. J Urol 2003; 170: 35-41 (Pubitemid 36734405)
4. Mills RD, Turner WH, Fleischmann A, Markwalder R, Thalmann GN, Studer UE,. Pelvic lymph node metastases from bladder cancer: outcome in 83 patients after radical cystectomy and pelvic lymphadenectomy. J Urol 2001; 166: 19-23 (Pubitemid 32565332)
5. Abdel-Latif M, Abol-Enein H, El-Baz M, Ghoneim MA,. Nodal involvement in bladder cancer cases treated with radical cystectomy: incidence and prognosis. J Urol 2004; 172: 85-9 (Pubitemid 41615044)
6. Greene FL, Page DL, Fleming ID, et al,. Urinary bladder. AJCC Cancer Staging Manual, 6th edn. New York: Springer, 2002: 335-40
7. Herr HW,. Superiority of ratio based lymph node staging for bladder cancer. J Urol 2003; 169: 943-5 (Pubitemid 36188130)
8. Dimashkieh HH, Lohse CM, Blute ML, Kwon ED, Leibovich BC, Cheville JC,. Extranodal extension in regional lymph nodes is associated with outcome in patients with renal cell carcinoma. J Urol 2006; 176: 1978-82; discussion 82-3
9. Srinivas V, Morse MJ, Herr HW, Sogani PC, Whitmore WF Jr,. Penile cancer: relation of extent of nodal metastasis to survival. J Urol 1987; 137: 880-2 (Pubitemid 17074883)
10. Beck SD, Cheng L, Bihrle R, Donohue JP, Foster RS,. Does the presence of extranodal extension in pathological stage B1 nonseminomatous germ cell tumor necessitate adjuvant chemotherapy? J Urol 2007; 177: 944-6 (Pubitemid 46216343)
11. Cheng L, Pisansky TM, Ramnani DM, et al,. Extranodal extension in lymph node-positive prostate cancer. Mod Pathol 2000; 13: 113-18 (Pubitemid 30109096)
12. Fleischmann A, Schobinger S, Markwalder R, et al,. Prognostic factors in lymph node metastases of prostatic cancer patients: the size of the metastases but not extranodal extension independently predicts survival. Histopathology 2008; 53: 468-75
13. Fleischmann A, Thalmann GN, Markwalder R, Studer UE,. Extracapsular extension of pelvic lymph node metastases from urothelial carcinoma of the bladder is an independent prognostic factor. J Clin Oncol 2005; 23: 2358-65 (Pubitemid 46218729)
14. Kassouf W, Leibovici D, Luongo T, et al,. Relevance of extracapsular extension of pelvic lymph node metastasis in patients with bladder cancer treated in the contemporary era. Cancer 2006; 107: 1491-5 (Pubitemid 44546908)
15. Fleischmann A, Thalmann GN, Markwalder R, Studer UE,. Prognostic implications of extracapsular extension of pelvic lymph node metastases in urothelial carcinoma of the bladder. Am J Surg Pathol 2005; 29: 89-95 (Pubitemid 40023955)
16. von der Maase H, Hansen SW, Roberts JT, et al,. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 2000; 18: 3068-77
17. Wright JL, Lin DW, Porter MP,. The association between extent of lymphadenectomy and survival among patients with lymph node metastases undergoing radical cystectomy. Cancer 2008; 112: 2401-8
18. Frank I, Cheville JC, Blute ML, et al,. Transitional cell carcinoma of the urinary bladder with regional lymph node involvement treated by cystectomy: clinicopathologic features associated with outcome. Cancer 2003; 97: 2425-31 (Pubitemid 36542481)
19. Herr HW,. Extent of surgery and pathology evaluation has an impact on bladder cancer outcomes after radical cystectomy. Urology 2003; 61: 105-8 (Pubitemid 36151723)
20. Leissner J, Hohenfellner R, Thuroff JW, Wolf HK,. Lymphadenectomy in patients with transitional cell carcinoma of the urinary bladder; significance for staging and prognosis. BJU Int 2000; 85: 817-23 (Pubitemid 30242784)