Use of a WHO-recommended algorithm to reduce mortality in seriously ill patients with HIV infection and smear-negative pulmonary tuberculosis in South Africa: An observational cohort study

The Lancet Infectious Diseases

Volumn 11, Issue 7, 2011, Pages 533-540

  Holtz, Timothy H ^a   Kabera, Gaëtan ^b   Mthiyane, Thuli ^b   Zingoni, Tainos ^c   Nadesan, Sidhambaram ^d   Ross, Douglas ^c   Allen, Jennifer ^b   Chideya, Sekai ^a   Sunpath, Henry ^d   Rustomjee, Roxana ^b  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^c St Mary's Hospital   (South Africa)

^d MCCORD HOSPITAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CEPHALOSPORIN DERIVATIVE; COTRIMOXAZOLE; GENTAMICIN; TUBERCULOSTATIC AGENT;

ADULT; ALGORITHM; ARTICLE; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; CONTROLLED STUDY; CRITICALLY ILL PATIENT; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SMEAR; SOUTH AFRICA; SPUTUM SMEAR; SURVIVAL; TUBERCULOSIS; UNSPECIFIED SIDE EFFECT; WORLD HEALTH ORGANIZATION;

ADOLESCENT; ADULT; ALGORITHMS; ANTI-HIV AGENTS; ANTITUBERCULAR AGENTS; COHORT STUDIES; HIV; HIV INFECTIONS; HUMANS; MYCOBACTERIUM TUBERCULOSIS; PROPORTIONAL HAZARDS MODELS; SOUTH AFRICA; TUBERCULOSIS, PULMONARY; WORLD HEALTH ORGANIZATION; YOUNG ADULT;

EID: 79959292012     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(11)70057-3     Document Type: Article

References (34)

1. Colebunders R, Bastian I A review of the diagnosis and treatment of smear-negative pulmonary tuberculosis. Int J Tuberc Lung Dis 2000, 4:97-107.
2. Getahun H, Harrington M, O'Brien R, Nunn P Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resource-constrained settings: informing urgent policy changes. Lancet 2007, 369:2042-2049.
3. Global tuberculosis control 2010 2010, WHO, World Health Organization, Geneva, WHO/HTM/TB/2010.7.
4. Bekker LG, Wood R The changing natural history of tuberculosis and HIV coinfection in an urban area of hyperendemicity. Clin Infect Dis 2010, 50(suppl 3):S208-S214.
5. Lawn SD, Bekker LG, Middelkoop K, Myer L, Wood R Impact of HIV infection on the epidemiology of tuberculosis in a peri-urban community in South Africa: the need for age-specific interventions. Clin Infect Dis 2006, 42:1040-1047.
6. Mortality and causes of death in South Africa: findings from death notification, 2007 Statistics South Africa, (accessed Jan 24, 2011). http://www.statssa.gov.za/publications/statsdownload.asp?PPN=P0309.3&SCH=4507.
7. Mortality and causes of death in South Africa: findings from death notification Statistics South Africa, (accessed Jan 24, 2011). http://www.statssa.gov.za/publications/statsdownload.asp?PPN=P0309.3&SCH=4790.
8. Brodie D, Schluger NW The diagnosis of tuberculosis. Clin Chest Med 2005, 26:247-271.
9. Apers L, Wijarajah C, Mutsvangwa J, Chigara N, Mason P, van der Stuyft P Accuracy of routine diagnosis of pulmonary tuberculosis in an area of high HIV prevalence. Int J Tuberc Lung Dis 2004, 8:945-951.
10. Elliott AM, Namaambo K, Allen BW, et al. Negative sputum smear results in HIV-positive patients with pulmonary tuberculosis in Lusaka, Zambia. Tuber Lung Dis 1993, 74:191-194.
11. Improving the diagnosis and treatment of smear-negative pulmonary and extrapulmonary tuberculosis among adults and adolescents: recommendations for HIV-prevalent and resource-constrained settings 2007, WHO, World Health Organization, Geneva, WHO/HTM/TB/2007.379.
12. Treatment of tuberculosis: guidelines for national programmes 2003, WHO, World Health Organization, Geneva, WHO/CDS/TB/2003.313. 3rd edn.
13. Wilson D, Nachega J, Morroni C, Chaisson R, Maartens G Diagnosing smear-negative tuberculosis using case definitions and treatment response in HIV-infected adults. Int J Tuberc Lung Dis 2006, 10:31-38.
14. Perkins MD, Cunningham J Facing the crisis: improving the diagnosis of tuberculosis in the HIV era. J Infect Dis 2007, 196(suppl 1):S15-S27.
15. Harries AD, Nyangulu DS, Kang'ombe C, et al. Treatment outcome of an unselected cohort of tuberculosis patients in relation to human immunodeficiency virus serostatus in Zomba Hospital, Malawi. Trans R Soc Trop Med Hyg 1998, 92:343-347.
16. Siddiqi K, Lambert M-L, Walley J Clinical diagnosis of smear-negative pulmonary tuberculosis in low-income countries: the current evidence. Lancet Infect Dis 2003, 3:288-296.
17. Bergman NJ A "treatment score" for primary and pulmonary tuberculosis. Cent Afr J Med 1995, 41:1-6.
18. Kanaya AM, Glidden DV, Chambers HF Identifying pulmonary tuberculosis in patients with negative sputum smear results. Chest 2001, 120:349-355.
19. Ayles H, Schaap A, Nota A, et al. Prevalence of tuberculosis, HIV and respiratory symptoms in two Zambian communities: implications for tuberculosis control in the era of HIV. PLoS One 2009, 4:e5602.
20. Chheng P, Tamhane A, Natpratan C, et al. Pulmonary tuberculosis among patients visiting a voluntary confidential counseling and testing center, Cambodia. Int J Tuberc Lung Dis 2008, 12(suppl 1):54-62.
21. Corbett EL, Zezai A, Cheung YB, et al. Provider-initiated symptom screening for tuberculosis in Zimbabwe: diagnostic value and the effect of HIV status. Bull World Health Organ 2010, 88:13-21.
22. Cain KP, McCarthy KD, Heilig CM, et al. An algorithm for tuberculosis screening and diagnosis in people with HIV. N Engl J Med 2010, 362:707-716.
23. Koppaka R, Bock N How reliable is chest radiography?. Toman's tuberculosis case cetection, treatment, and monitoring 2004, World Health Organization, Geneva. 2nd edn. T.R. Frieden (Ed.).
24. Hudson CP, Wood R, Maartens G Diagnosing HIV-associated tuberculosis: reducing costs and diagnostic delay. Int J Tuberc Lung Dis 2000, 4:240-245.
25. Saranchuk P, Boulle A, Hilderbrand K, et al. Evaluation of a diagnostic algorithm for smear-negative pulmonary tuberculosis in HIV-infected adults. S Afr Med J 2007, 97:517-523.
26. Hargreaves NJ, Kadzakumanja O, Whitty CJ, Salaniponi FM, Harries AD, Squire SB 'Smear-negative' pulmonary tuberculosis in a DOTS programme: poor outcomes in an area of high HIV seroprevalence. Int J Tuberc Lung Dis 2001, 5:847-854.
27. Bakari M, Arbeit RD, Mtei L, et al. Basis for treatment of tuberculosis among HIV-infected patients in Tanzania: the role of chest x-ray and sputum culture. BMC Infect Dis 2008, 8:32.
28. Tamhane A, Chheng P, Dobbs T, Mak S, Sar B, Kimerling ME Predictors of smear-negative pulmonary tuberculosis in HIV-infected patients, Battambang, Cambodia. Int J Tuberc Lung Dis 2009, 13:347-354.
29. Monkongdee P, McCarthy KD, Cain KP, et al. Yield of acid-fast smear and mycobacterial culture for tuberculosis diagnosis in people with human immunodeficiency virus. Am J Respir Crit Care Med 2009, 180:903-908.
30. Harries AD, Zachariah R, Corbett EL, et al. The HIV-associated tuberculosis epidemic-when will we act?. Lancet 2010, 375:1906-1919.
31. Boehme CC, Nabeta P, Hillemann D, et al. Rapid molecular detection of tuberculosis and rifampin resistance. N Engl J Med 2010, 363:1005-1015.
32. Tuberculosis diagnostics automated DNA test: endorsement and recommendations WHO, (accessed April 8, 2011). http://www.stoptb.org/wg/gli/assets/documents/xpert_factsheet.pdf.
33. Treatment of tuberculosis: guidelines 2010, WHO, World Health Organization, Geneva, WHO/HTM/TB/2009.420. 4th edn.
34. Guidelines for intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource-constrained settings 2010, WHO, World Health Organization, Geneva.