Relative quantitation of cell-free fetal DNA in maternal plasma using autosomal DNA markers

Clinica Chimica Acta

Volumn 412, Issue 17-18, 2011, Pages 1539-1543

  Davanos, Nikolaos ^a   Spathas, Dionysios Haralampos ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

Cell free fetal DNA; Fluorescent PCR; Maternal plasma; STRs

Indexed keywords

DNA MARKER;

ARTICLE; CELL FREE SYSTEM; CHIMERA; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; FETUS; FLUORESCENCE ANALYSIS; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCUS; GENETIC CORRELATION; GESTATIONAL AGE; HUMAN; MATERNAL PLASMA; MOTHER FETUS RELATIONSHIP; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SHORT TANDEM REPEAT;

BIOLOGICAL MARKERS; DNA; FEMALE; HUMANS; MICROSATELLITE REPEATS; POLYMERASE CHAIN REACTION; PREGNANCY;

EID: 79959290365     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2011.04.032     Document Type: Article

References (23)

1. Lo Y.M.D., Corbetta N., Chamberlain P.F., et al. Presence of fetal DNA in maternal plasma and serum. Lancet 1997, 350:485-487.
2. Alberry M., Maddocks D., Jones M., et al. Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast. Prenat Diagn 2007, 27:415-418.
3. Honda H., Miharu N., Ohashi Y., Ohama K. Successful diagnosis of fetal gender using conventional PCR analysis of maternal serum. Clin Chem 2001, 47:41-46.
4. Honda H., Miharu N., Ohashi Y., et al. Fetal gender determination in early pregnancy through qualitative and quantitative analysis of fetal DNA in maternal serum. Hum Genet 2002, 110:75-79.
5. Zhu B., Sun Q.-W., Lu Y.-C., Sun M.-M., Wang L.-J., Huang X.-H. Prenatal fetal sex diagnosis by detecting amelogenin gene in maternal plasma. Prenat Diagn 2005, 25:577-581.
6. Zimmermann B., El Sheikhah A., Nicolaides K., Holzgreve W., Hahn S. Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma. Clin Chem 2005, 51:1598-1604.
7. Deng Z., Wu G., Li Q., et al. Noninvasive genotyping of 9 Y-chromosome specific STR loci using circulatory fetal DNA in maternal plasma by multiplex PCR. Prenat Diag 2006, 26:362-368.
8. Stanghellini I., Bertorelli R., Capone L., et al. Quantitation of fetal DNA in maternal serum during the first trimester of pregnancy by the use of a DAZ repetitive probe. Mol Hum Reprod 2006, 12:587-591.
9. Illanes S., Denbow M., Kailasam C., Finning K., Soothill P.W. Early detection of cell-free fetal DNA in maternal plasma. Early Hum Dev 2007, 83:563-566.
10. Lo Y.M.D., Tein M.S.C., Lau T.K., et al. Quantitative analysis of fetal DNA in maternal plasma and serum: implications for noninvasive prenatal diagnosis. Am J Hum Genet 1998, 62:768-775.
11. Lo Y.M.D., Lau T.K., Zhang J., et al. Increased fetal DNA concentrations in the plasma of pregnant women carrying fetuses with trisomy 21. Clin Chem 1999, 45:1747-1751.
12. Spencer K., de Kok J.B., Swinkels D.W. Increased total cell-free DNA in the serum of pregnant women carrying a fetus affected by trisomy 21. Prenat Diagn 2003, 23:580-583.
13. Wataganara T., LeShane E.S., Farina A., et al. Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18. Hum Genet 2003, 112:204-208.
14. Lo Y.M., Leung T.N., Tein M.S., et al. Quantitative abnormalities of fetal DNA in maternal serum in preeclampsia. Clin Chem 1999, 45:184-188.
15. Bischoff F.Z., Lewis D.E., Simpson J.L. Cell-free fetal DNA in maternal blood: kinetics, source and structure. Hum Reprod Update 2005, 11:59-67.
16. Hahn S., Huppertz B., Holzgreve W. Fetal cells and cell free fetal nucleic acids in maternal blood: new tools to study abnormal placentation?. Placenta 2005, 26:515-526.
17. Bauer M., Hutterer G., Eder M., et al. A prospective analysis of cell-free fetal DNA concentration in maternal plasma as an indicator for adverse pregnancy outcome. Prenat Diagn 2006, 26:831-836.
18. Tang N.L.S., Leung T.N., Zhang J., Lau T.K., LoYMD Detection of fetal-derived paternally inherited X-chromosome polymorphisms in maternal plasma. Clin Chem 1999, 11:2033-2035.
19. Pertl B., Sekizawa A., Samura O., Orescovic I., Rahaim P.T., Bianchi D.W. Detection of male and female fetal DNA in maternal plasma by multiplex fluorescent polymerase chain reaction amplification of short tandem repeats. Hum Genet 2000, 106:45-49.
20. Birch L., English C.A., O'Donoghue K., Barigye O., Fisk N.M., Keer J.T. Accurate and robust quantification of circulating fetal and total DNA in maternal plasma from 5 to 41weeks of gestation. Clin Chem 2005, 51:312-320.
21. Liu F.M., Wang X.Y., Feng X., Wang W., Ye Y.X., Chen H. Feasibility study of using fetal DNA in maternal plasma for non-invasive prenatal diagnosis. Acta Obset Gyn Scand 2007, 86:535-541.
22. Tang D.L., Li Y., Zhou X., Li X., Zheng F. Multiplex fluorescent PCR for noninvasive prenatal detection of fetal-derived paternally inherited diseases using circulatory fetal DNA in maternal plasma. Eur J Obstet Gynecol Reprod Biol 2009, 144(1):35-39.
23. Millson A.S., Spangler F.L., Wittwer C.T., Lyon E. Comparison of automated short tandem repeat and manual variable number of tandem repeat analysis of chimerism in bone marrow transplant patients. Diagnostic Mol Pathol 2000, 9(2):91-97.