Increase in the heritability of asthma from 1994 to 2003 among adolescent twins

Respiratory Medicine

Volumn 105, Issue 8, 2011, Pages 1147-1152

  Thomsen, Simon Francis ^a   Van Der Sluis, Sophie ^b   Kyvik, Kirsten Ohm ^c   Skytthe, Axel ^c   Skadhauge, Lars Rauff ^d   Backer, Vibeke ^a  

^a BISPEBJERG HOSPITAL   (Denmark)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d Hospital of South Jutland   (Denmark)

Author keywords

Asthma; Environment; Genetics; Prevalence; Twin study

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ASTHMA; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; FEMALE; GENE EXPRESSION; HEREDITY; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOZYGOTIC TWINS; PRIORITY JOURNAL; QUESTIONNAIRE; REGISTER;

ADOLESCENT; ASTHMA; CHILD; DENMARK; DISEASES IN TWINS; ENVIRONMENTAL EXPOSURE; FEMALE; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; MALE; PREVALENCE; QUESTIONNAIRES; REGISTRIES; RISK FACTORS; TWINS; YOUNG ADULT;

EID: 79959274682     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2011.03.007     Document Type: Article

References (23)

1. Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H, ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC phases one and three repeat multi-country cross-sectional surveys. Lancet 2006;368:733-43.
2. Douwes J, Pearce N. Asthma and the westernization 'package'. Int J Epidemiol 2002;31:1098-102.
3. Anandan C, Nurmatov U, van Schayck OC, Sheikh A. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy 2010;65:152-67.
4. Kyvik KO, Green A, Beck-Nielsen H. The new Danish Twin Register: establishment and analysis of twinning rates. Int J Epidemiol 1995;24:589-96.
5. Skytthe A, Kyvik K, Bathum L, Holm N, Vaupel JW, Christensen K. The Danish Twin Registry in the new millennium. Twin Res Hum Genet 2006;9:763-71. (Pubitemid 46093754)
6. Skadhauge LR, Christensen K, Kyvik KO, Sigsgaard T. Genetic and environmental influence on asthma: a population-based study of 11,688 Danish twin pairs. Eur Respir J 1999;13:8-14. (Pubitemid 29079212)
7. Thomsen SF, van der Sluis S, Kyvik KO, Skytthe A, Backer V. Estimates of asthma heritability in a large twin sample. Clin Exp Allergy 2010;40:1054-61.
8. Christiansen L, Frederiksen H, Schousboe K, Skytthe A, von Wurmb-Schwark N, Christensen K, Kyvik K. Age- and sex-differences in the validity of questionnaire-based zygosity in twins. Twin Res 2003;6:275-8. (Pubitemid 37046226)
9. McGue M. When assessing twin concordance, use the probandwise not the pairwise rate. Schizophr Bull 1992;18:171-6.
10. Neale MC, Cardon LR. Methodology for genetic studies of twins and families. Dordrecht, The Netherlands: Kluwer Academic Publishers; 1992.
11. Evans DM, Gillespie NA, Martin NG. Biometrical genetics. Biol Psychol 2002;61:33-51. (Pubitemid 35248148)
12. Neale MC, Boker SM, Xie G, Maes HH In: Richmond VA, editor. Mx statistical modeling. 5th ed. Department of Psychiatry, Medical College of Virginia; 1999.
13. Visscher PM, Hill WG, Wray NR. Heritability in the genomics era - concepts and misconceptions. Nat Rev Genet 2008;9:255-66. (Pubitemid 351399832)
14. Rice TK. Familial resemblance and heritability. Adv Genet 2008;60:35-49.
15. Rose SP. Commentary: heritability estimates - long past their sell-by date. Int J Epidemiol 2006;35:525-7. (Pubitemid 43985523)
16. Anderson HR, Gupta R, Strachan DP, Limb ES. 50 years of asthma: UK trends from 1955 to 2004. Thorax 2007;62:85-90.
17. Thomsen SF, Ulrik CS, Larsen K, Backer V. Change in prevalence of asthma in Danish children and adolescents. Ann Allergy Asthma Immunol 2004;92:506-11. (Pubitemid 39236813)
18. Nystad W, Magnus P, Gulsvik A, Skarpaas IJ, Carlsen KH. Changing prevalence of asthma in school children: evidence for diagnostic changes in asthma in two surveys 13 yrs apart. Eur Respir J 1997;10:1046-51. (Pubitemid 27201808)
19. Gibson G. Decanalization and the origin of complex disease. Nat Rev Genet 2009;10:134-40.
20. Hawkes CH. Twin studies in medicine - what do they tell us? QJM 1997;90:311-21.
21. Thomsen S.F. Risk factors for asthma in adult twins. Faculty of Health Sciences, University of Copenhagen, PhD Thesis, 2006.
22. Vercelli D. Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol 2008;8:169-82. (Pubitemid 351323288)
23. Vercelli D. Gene-environment interactions in asthma and allergy: the end of the beginning? Curr Opin Allergy Clin Immunol 2010;10:145-8.