메뉴 건너뛰기




Volumn 11, Issue , 2011, Pages

Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CLADRIBINE; DNA FRAGMENT; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN INHIBITOR; S 3I 201; STAT3 PROTEIN; UNCLASSIFIED DRUG; AMINOSALICYLIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; BENZENESULFONIC ACID DERIVATIVE; NSC 74859; STAT3 PROTEIN, HUMAN; TUMOR PROTEIN;

EID: 79959248152     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-255     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 6944235003 scopus 로고    scopus 로고
    • Multiple myeloma
    • 10.1056/NEJMra041875, 15509819
    • Kyle RA, Rajkumar SV. Multiple myeloma. N Engl J Med 2004, 351:1860-1873. 10.1056/NEJMra041875, 15509819.
    • (2004) N Engl J Med , vol.351 , pp. 1860-1873
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 2
    • 33747401889 scopus 로고    scopus 로고
    • Fifth biannual report of the cochrane haematologic malignancies group--focus on multiple myeloma
    • 10.1093/jnci/djj328, 16912255
    • Naumann F, Weingart O, Kruse E, Schulz H, Bohlius J, Hulsewede H, Engert A. Fifth biannual report of the cochrane haematologic malignancies group--focus on multiple myeloma. J Natl Cancer Inst 2006, 98:E2-E. 10.1093/jnci/djj328, 16912255.
    • (2006) J Natl Cancer Inst , vol.98
    • Naumann, F.1    Weingart, O.2    Kruse, E.3    Schulz, H.4    Bohlius, J.5    Hulsewede, H.6    Engert, A.7
  • 3
    • 23844481419 scopus 로고    scopus 로고
    • Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications
    • 10.2174/1568009054863618, 16178817
    • Robak T, Korycka A, Kasznicki M, Wrzesien-Kus A, Smolewski P. Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications. Curr Cancer Drug Targets 2005, 5(6):421-444. 10.2174/1568009054863618, 16178817.
    • (2005) Curr Cancer Drug Targets , vol.5 , Issue.6 , pp. 421-444
    • Robak, T.1    Korycka, A.2    Kasznicki, M.3    Wrzesien-Kus, A.4    Smolewski, P.5
  • 4
    • 33750601477 scopus 로고    scopus 로고
    • Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity
    • 10.2174/092986706778742918, 17168705
    • Robak T, Lech-Maranda E, Korycka A, Robak E. Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity. Curr Med Chem 2006, 13:3165-3189. 10.2174/092986706778742918, 17168705.
    • (2006) Curr Med Chem , vol.13 , pp. 3165-3189
    • Robak, T.1    Lech-Maranda, E.2    Korycka, A.3    Robak, E.4
  • 5
    • 0343290261 scopus 로고    scopus 로고
    • Comparison of the effects of 2-chlorodeoxyadenosine and melphalan on myeloma cell lines
    • 10.1016/0145-2126(95)00128-X, 8628014
    • Hjertner O, Borset M, Waage A. Comparison of the effects of 2-chlorodeoxyadenosine and melphalan on myeloma cell lines. Leuk Res 1996, 20:155-160. 10.1016/0145-2126(95)00128-X, 8628014.
    • (1996) Leuk Res , vol.20 , pp. 155-160
    • Hjertner, O.1    Borset, M.2    Waage, A.3
  • 6
    • 33751090057 scopus 로고    scopus 로고
    • 2-CdA in the treatment of hairy cell leukemia: a review of long-term follow-up
    • 10.1080/10428190600822052, 17107901
    • Gidron A, Tallman MS. 2-CdA in the treatment of hairy cell leukemia: a review of long-term follow-up. Leuk Lymphoma 2006, 47(11):2301-2307. 10.1080/10428190600822052, 17107901.
    • (2006) Leuk Lymphoma , vol.47 , Issue.11 , pp. 2301-2307
    • Gidron, A.1    Tallman, M.S.2
  • 7
    • 70449433722 scopus 로고    scopus 로고
    • Cladribine in the treatment of hairy cell leukemia: initial and subsequent results
    • Huynh E, Sigal D, Saven A. Cladribine in the treatment of hairy cell leukemia: initial and subsequent results. Leuk Lymphoma 2009, 50(Suppl 1):12-17.
    • (2009) Leuk Lymphoma , vol.50 , Issue.SUPPL. 1 , pp. 12-17
    • Huynh, E.1    Sigal, D.2    Saven, A.3
  • 8
    • 22044444135 scopus 로고    scopus 로고
    • Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern University experience
    • 10.1182/blood-2005-01-0173, 15761021
    • Chadha P, Rademaker AW, Mendiratta P, Kim B, Evanchuk DM, Hakimian D, Peterson LC, Tallman MS. Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern University experience. Blood 2005, 106:241-246. 10.1182/blood-2005-01-0173, 15761021.
    • (2005) Blood , vol.106 , pp. 241-246
    • Chadha, P.1    Rademaker, A.W.2    Mendiratta, P.3    Kim, B.4    Evanchuk, D.M.5    Hakimian, D.6    Peterson, L.C.7    Tallman, M.S.8
  • 10
    • 4444288930 scopus 로고    scopus 로고
    • An update: 12-year follow-up of patients with hairy cell leukemia following treatment with 2-chlorodeoxyadenosine
    • 10.1038/sj.leu.2403418, 15229616
    • Jehn U, Bartl R, Dietzfelbinger H, Haferlach T, Heinemann V. An update: 12-year follow-up of patients with hairy cell leukemia following treatment with 2-chlorodeoxyadenosine. Leukemia 2004, 18:1476-1481. 10.1038/sj.leu.2403418, 15229616.
    • (2004) Leukemia , vol.18 , pp. 1476-1481
    • Jehn, U.1    Bartl, R.2    Dietzfelbinger, H.3    Haferlach, T.4    Heinemann, V.5
  • 12
    • 77953196181 scopus 로고    scopus 로고
    • Efficacy of rituximab and cladribine in patients with chronic lymphocytic leukemia and feasibility of stem cell mobilization: a prospective multicenter phase II trial (protocol SAKK 34/02)
    • 10.3109/10428191003624231, 20218808
    • Leupin N, Schuller JC, Solenthaler M, Heim D, Rovo A, Beretta K, Gregor M, Bargetzi MJ, Brauchli P, Himmelmann A, Hanselmann S, Zenhäusern R. Efficacy of rituximab and cladribine in patients with chronic lymphocytic leukemia and feasibility of stem cell mobilization: a prospective multicenter phase II trial (protocol SAKK 34/02). Leuk Lymphoma 2010, 51:613-619. 10.3109/10428191003624231, 20218808.
    • (2010) Leuk Lymphoma , vol.51 , pp. 613-619
    • Leupin, N.1    Schuller, J.C.2    Solenthaler, M.3    Heim, D.4    Rovo, A.5    Beretta, K.6    Gregor, M.7    Bargetzi, M.J.8    Brauchli, P.9    Himmelmann, A.10    Hanselmann, S.11    Zenhäusern, R.12
  • 13
    • 77958155612 scopus 로고    scopus 로고
    • Beyond hairy cell: the activity of cladribine in other hematologic malignancies
    • 10.1182/blood-2010-02-246140, 20634380
    • Sigal DS, Miller HJ, Schram ED, Saven A. Beyond hairy cell: the activity of cladribine in other hematologic malignancies. Blood 2010, 116:2884-2896. 10.1182/blood-2010-02-246140, 20634380.
    • (2010) Blood , vol.116 , pp. 2884-2896
    • Sigal, D.S.1    Miller, H.J.2    Schram, E.D.3    Saven, A.4
  • 16
    • 0027396904 scopus 로고
    • 2-Chlorodeoxyadenosine for multiple myeloma
    • Niesvizky R, Siegel D, Michaeli J. 2-Chlorodeoxyadenosine for multiple myeloma. Blood 1993, 81:868-869.
    • (1993) Blood , vol.81 , pp. 868-869
    • Niesvizky, R.1    Siegel, D.2    Michaeli, J.3
  • 17
    • 0027404803 scopus 로고
    • Biology and treatment of multiple myeloma
    • 10.1016/0268-960X(93)90021-U, 8467229
    • Niesvizky R, Siegel D, Michaeli J. Biology and treatment of multiple myeloma. Blood Rev 1993, 7:24-33. 10.1016/0268-960X(93)90021-U, 8467229.
    • (1993) Blood Rev , vol.7 , pp. 24-33
    • Niesvizky, R.1    Siegel, D.2    Michaeli, J.3
  • 19
    • 0027455425 scopus 로고
    • 2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms
    • 10.1038/bjc.1993.3, 1968239, 8094002
    • Nagourney RA, Evans SS, Messenger JC, Su YZ, Weisenthal LM. 2 chlorodeoxyadenosine activity and cross resistance patterns in primary cultures of human hematologic neoplasms. Br J Cancer 1993, 67:10-14. 10.1038/bjc.1993.3, 1968239, 8094002.
    • (1993) Br J Cancer , vol.67 , pp. 10-14
    • Nagourney, R.A.1    Evans, S.S.2    Messenger, J.C.3    Su, Y.Z.4    Weisenthal, L.M.5
  • 21
    • 79957465550 scopus 로고    scopus 로고
    • Mechanism of Action of Pentostatin and Cladribine in Hairy Cell Leukemia
    • Johnston JB. Mechanism of Action of Pentostatin and Cladribine in Hairy Cell Leukemia. Leuk Lymphoma 2011,
    • (2011) Leuk Lymphoma
    • Johnston, J.B.1
  • 22
    • 77957942585 scopus 로고    scopus 로고
    • Epigenetics and microRNAs combine to modulate the MDM2/p53 axis in myeloma
    • 10.1016/j.ccr.2010.10.004, 20951939
    • Chesi M, Bergsagel PL. Epigenetics and microRNAs combine to modulate the MDM2/p53 axis in myeloma. Cancer Cell 2010, 18:299-300. 10.1016/j.ccr.2010.10.004, 20951939.
    • (2010) Cancer Cell , vol.18 , pp. 299-300
    • Chesi, M.1    Bergsagel, P.L.2
  • 23
    • 77957936826 scopus 로고    scopus 로고
    • Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development
    • 10.1016/j.ccr.2010.09.005, 20951946
    • Pichiorri F, Suh SS, Rocci A, De Luca L, Taccioli C, Santhanam R, Zhou W, Benson DM, Hofmainster C, Alder H, et al. Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development. Cancer Cell 2010, 18:367-381. 10.1016/j.ccr.2010.09.005, 20951946.
    • (2010) Cancer Cell , vol.18 , pp. 367-381
    • Pichiorri, F.1    Suh, S.S.2    Rocci, A.3    De Luca, L.4    Taccioli, C.5    Santhanam, R.6    Zhou, W.7    Benson, D.M.8    Hofmainster, C.9    Alder, H.10
  • 26
    • 5444274132 scopus 로고    scopus 로고
    • Activating mutations in STAT3 and STAT5 differentially affect cellular proliferation and apoptotic resistance in multiple myeloma cells
    • Hodge DR, Xiao W, Wang LH, Li D, Farrar WL. Activating mutations in STAT3 and STAT5 differentially affect cellular proliferation and apoptotic resistance in multiple myeloma cells. Cancer Biol Ther 2004, 3:188-194.
    • (2004) Cancer Biol Ther , vol.3 , pp. 188-194
    • Hodge, D.R.1    Xiao, W.2    Wang, L.H.3    Li, D.4    Farrar, W.L.5
  • 27
    • 38849199799 scopus 로고    scopus 로고
    • STAT3 as a target for inducing apoptosis in solid and hematological tumors
    • 10.1038/cr.2008.18, 2610254, 18227858
    • Al Zaid Siddiquee K, Turkson J. STAT3 as a target for inducing apoptosis in solid and hematological tumors. Cell Res 2008, 18:254-267. 10.1038/cr.2008.18, 2610254, 18227858.
    • (2008) Cell Res , vol.18 , pp. 254-267
    • Al Zaid Siddiquee, K.1    Turkson, J.2
  • 28
    • 77955675650 scopus 로고    scopus 로고
    • HDAC inhibition synergistically enhances alkylator-induced DNA damage responses and apoptosis in multiple myeloma cells
    • 10.1016/j.canlet.2010.04.014, 20447761
    • Lee CK, Wang S, Huang X, Ryder J, Liu B. HDAC inhibition synergistically enhances alkylator-induced DNA damage responses and apoptosis in multiple myeloma cells. Cancer Lett 2010, 296:233-240. 10.1016/j.canlet.2010.04.014, 20447761.
    • (2010) Cancer Lett , vol.296 , pp. 233-240
    • Lee, C.K.1    Wang, S.2    Huang, X.3    Ryder, J.4    Liu, B.5
  • 30
    • 1042302005 scopus 로고    scopus 로고
    • The STATs of cancer--new molecular targets come of age
    • 10.1038/nrc1275, 14964307
    • Yu H, Jove R. The STATs of cancer--new molecular targets come of age. Nat Rev Cancer 2004, 4:97-105. 10.1038/nrc1275, 14964307.
    • (2004) Nat Rev Cancer , vol.4 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 31
    • 64849111865 scopus 로고    scopus 로고
    • Targeting STAT3 in cancer: how successful are we?
    • 10.1517/13543780802565791, 2610472, 19053881
    • Yue P, Turkson J. Targeting STAT3 in cancer: how successful are we?. Expert Opin Investig Drugs 2009, 18:45-56. 10.1517/13543780802565791, 2610472, 19053881.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 45-56
    • Yue, P.1    Turkson, J.2
  • 33
    • 0025935563 scopus 로고
    • On the pharmacokinetics of 2-chloro-2'-deoxyadenosine in humans
    • Liliemark J, Juliusson G. On the pharmacokinetics of 2-chloro-2'-deoxyadenosine in humans. Cancer Res 1991, 51:5570-5572.
    • (1991) Cancer Res , vol.51 , pp. 5570-5572
    • Liliemark, J.1    Juliusson, G.2
  • 34
    • 0033949050 scopus 로고    scopus 로고
    • Pharmacokinetics of 2-chloro-2'-deoxyadenosine administered subcutaneously or by continuous intravenous infusion
    • 10.1007/s002800000129, 10912576
    • Sonderegger T, Betticher DC, Cerny T, Lauterburg BH. Pharmacokinetics of 2-chloro-2'-deoxyadenosine administered subcutaneously or by continuous intravenous infusion. Cancer Chemother Pharmacol 2000, 46:40-42. 10.1007/s002800000129, 10912576.
    • (2000) Cancer Chemother Pharmacol , vol.46 , pp. 40-42
    • Sonderegger, T.1    Betticher, D.C.2    Cerny, T.3    Lauterburg, B.H.4
  • 35
    • 34547106018 scopus 로고    scopus 로고
    • Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
    • 10.1038/nrc2189, 17646864
    • Hideshima T, Mitsiades C, Tonon G, Richardson PG, Anderson KC. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nat Rev Cancer 2007, 7:585-598. 10.1038/nrc2189, 17646864.
    • (2007) Nat Rev Cancer , vol.7 , pp. 585-598
    • Hideshima, T.1    Mitsiades, C.2    Tonon, G.3    Richardson, P.G.4    Anderson, K.C.5
  • 36
    • 58249101211 scopus 로고    scopus 로고
    • Bone marrow microenvironment and the identification of new targets for myeloma therapy
    • 10.1038/leu.2008.259, 18843284
    • Podar K, Chauhan D, Anderson KC. Bone marrow microenvironment and the identification of new targets for myeloma therapy. Leukemia 2009, 23:10-24. 10.1038/leu.2008.259, 18843284.
    • (2009) Leukemia , vol.23 , pp. 10-24
    • Podar, K.1    Chauhan, D.2    Anderson, K.C.3
  • 37
    • 34748840882 scopus 로고    scopus 로고
    • Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor-dependent human lung cancer cells
    • 10.1158/1535-7163.MCT-06-0761, 17876048
    • Edwards A, Li J, Atadja P, Bhalla K, Haura EB. Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor-dependent human lung cancer cells. Mol Cancer Ther 2007, 6:2515-2524. 10.1158/1535-7163.MCT-06-0761, 17876048.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2515-2524
    • Edwards, A.1    Li, J.2    Atadja, P.3    Bhalla, K.4    Haura, E.B.5
  • 38
    • 77953648655 scopus 로고    scopus 로고
    • AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit
    • 10.1182/blood-2009-07-231985, 20233974
    • Lin TY, Fenger J, Murahari S, Bear MD, Kulp SK, Wang D, Chen CS, Kisseberth WC, London CA. AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit. Blood 2010, 115:4217-4225. 10.1182/blood-2009-07-231985, 20233974.
    • (2010) Blood , vol.115 , pp. 4217-4225
    • Lin, T.Y.1    Fenger, J.2    Murahari, S.3    Bear, M.D.4    Kulp, S.K.5    Wang, D.6    Chen, C.S.7    Kisseberth, W.C.8    London, C.A.9
  • 42
    • 68149110019 scopus 로고    scopus 로고
    • The role of the insulin-like growth factor 1 receptor axis in multiple myeloma
    • 10.1080/13813450902736583, 19234898
    • Menu E, van Valckenborgh E, van Camp B, Vanderkerken K. The role of the insulin-like growth factor 1 receptor axis in multiple myeloma. Arch Physiol Biochem 2009, 115:49-57. 10.1080/13813450902736583, 19234898.
    • (2009) Arch Physiol Biochem , vol.115 , pp. 49-57
    • Menu, E.1    van Valckenborgh, E.2    van Camp, B.3    Vanderkerken, K.4
  • 43
    • 0037945211 scopus 로고    scopus 로고
    • HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells
    • 10.1038/sj.onc.1206394, 12761490
    • Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, Schmidt M, Mills GB, Mendelsohn J, Fan Z. HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Oncogene 2003, 22:3205-3212. 10.1038/sj.onc.1206394, 12761490.
    • (2003) Oncogene , vol.22 , pp. 3205-3212
    • Knuefermann, C.1    Lu, Y.2    Liu, B.3    Jin, W.4    Liang, K.5    Wu, L.6    Schmidt, M.7    Mills, G.B.8    Mendelsohn, J.9    Fan, Z.10
  • 44
    • 77954958218 scopus 로고    scopus 로고
    • Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin
    • 10.1038/onc.2010.180, 20498641
    • Wang S, Huang X, Lee CK, Liu B. Elevated expression of erbB3 confers paclitaxel resistance in erbB2-overexpressing breast cancer cells via upregulation of Survivin. Oncogene 2010, 29:4225-4236. 10.1038/onc.2010.180, 20498641.
    • (2010) Oncogene , vol.29 , pp. 4225-4236
    • Wang, S.1    Huang, X.2    Lee, C.K.3    Liu, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.