Metabolites as global regulators: A new view of protein regulation: Systematic investigation of metabolite-protein interactions may help bridge the gap between genome-wide association studies and small molecule screening studies

BioEssays

Volumn 33, Issue 7, 2011, Pages 485-489

  Li, Xiyan ^a   Snyder, Michael ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Mass spectrometry; Metabolite; Metabolite protein interaction; Protein function regulation; Small molecule drug

Indexed keywords

CHOLESTEROL; DIACYLGLYCEROL; ERGOSTEROL; G PROTEIN COUPLED RECEPTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; LIPID BINDING PROTEIN; NUCLEIC ACID; PALMITIC ACID; PROTEIN; PROTEIN KINASE; PROTEIN KINASE C; PROTEOME; PURINE; PYRIMIDINE; STEROID;

ACCURACY; ARTICLE; BINDING AFFINITY; BIOLOGY; CELL LYSATE; DRUG DEVELOPMENT; ENZYME ACTIVITY; ENZYME REGULATION; GENE INTERACTION; GENETIC ASSOCIATION; HYDROPHILICITY; HYDROPHOBICITY; IN VIVO STUDY; LACTOSE OPERON; LIQUID CHROMATOGRAPHY; MASS; MASS SPECTROMETRY; METABOLITE; MICROARRAY ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATION; PHENOTYPE; PROTEIN FUNCTION; PROTEIN IMMOBILIZATION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEOMICS; SACCHAROMYCES CEREVISIAE; SENSITIVITY ANALYSIS; STOICHIOMETRY; SURFACE PLASMON RESONANCE;

ANIMALS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MASS SPECTROMETRY; MODELS, THEORETICAL; PROTEIN BINDING; PROTEINS;

EID: 79959230308     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201100026     Document Type: Article

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