ACS chemical neuroscience molecule spotlight on ELND006: Another γ-secretase inhibitor fails in the clinic

ACS Chemical Neuroscience

Volumn 2, Issue 6, 2011, Pages 279-280

  Hopkins, Corey R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

secretase; Alzheimer's disease; clinical trials; ELND006; semagacestat

Indexed keywords

AMYLOID BETA PROTEIN; ELND 006; GAMMA SECRETASE INHIBITOR; SEMAGACESTAT; TARENFLURBIL; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; DRUG TREATMENT FAILURE; HUMAN; IC 50; LIVER DISEASE; NEUROSCIENCE; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; REVIEW;

Γ-SECRETASE; ALZHEIMER'S DISEASE; CLINICAL TRIALS; ELND006; SEMAGACESTAT;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; HUMANS; NEUROSCIENCES; PROTEASE INHIBITORS; PYRAZOLES; QUINOLINES; SOCIETIES, SCIENTIFIC; TREATMENT FAILURE;

EID: 79959223299     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn2000469     Document Type: Review

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