Systematic literature review of symptoms, signs and severity of serologically confirmed nephropathia epidemica in paediatric and adult patients

Scandinavian Journal of Infectious Diseases

Volumn 43, Issue 6-7, 2011, Pages 405-410

  Huttunen, Niilo Pekka ^a   Mäkelä, Satu ^b,c   Pokka, Tytti ^a   Mustonen, Jukka ^b,c   Uhari, Matti ^a  

^a UNIVERSITY OF OULU   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

clinical picture; comparison; puumala virus; zoonosis

Indexed keywords

ABDOMINAL PAIN; ANURIA; ARTHRALGIA; BACKACHE; BLEEDING; BRAIN HEMORRHAGE; CONJUNCTIVITIS; CONVULSION; DIARRHEA; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; DIZZINESS; ENCEPHALITIS; EPISTAXIS; FEVER; GUILLAIN BARRE SYNDROME; HEADACHE; HEMATEMESIS; HEMATURIA; HUMAN; HYPERTENSION; HYPOPITUITARISM; INTRAOCULAR HEMORRHAGE; KIDNEY DISEASE; LEUKOCYTOSIS; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; METRORRHAGIA; MULTIPLE ORGAN FAILURE; MYALGIA; NAUSEA; NECROSIS; NEPHROPATHIA EPIDEMICA; OLIGURIA; POLYURIA; PROTEINURIA; PUUMALA VIRUS; REVIEW; SEROLOGY; SHOCK; SORE THROAT; THROMBOCYTOPENIA; UNCONSCIOUSNESS; UREMIA; VISUAL DISORDER; VOMITING;

ADULT; AGED; CHILD; CHILD, PRESCHOOL; FEMALE; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; MALE; MIDDLE AGED; PUUMALA VIRUS;

EID: 79959194082     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2011.559666     Document Type: Review

References (68)

1. Settergren B, Juto P, Trollfors B, Wadell G, Norrby SR. Hemorrhagic complications and other clinical findings in nephropathia epidemica in Sweden: a study of 355 serologically verified cases. J Infect Dis 1988;157:380-2. (Pubitemid 18061257)
2. Zetterholm S. Akuta nefriter simulerande akuta bukfall. (In Swedish) Läkartidningen 1934;31:425-9.
3. Muranyi W, Bahr U, Zeier M, van der Woude FJ. Hantavirus infections. Am J Soc Nephrol 2005;16:3669-79.
4. Petterson L, Klingström J, Hardestam J, Lundkvist Å. Hantavirus RNA in saliva from patients with hemorrhagic fever with renal syndrome. Emerg Infect Dis 2008;14:406-10.
5. Niklasson BS. Haemorrhagic fever with renal syndrome, virological and epidemiological aspects. Pediatr Nephrol 1992;6:201-4.
6. Ahlm C, Settergren B, Gothefors L, Juto P. Nephropathia epidemica (hemorrhagic fever with renal syndrome) in children: clinical characteristics. Pediatr Infect Dis J 1994;13:45-9. (Pubitemid 24039294)
7. Mustonen J, Huttunen NP, Brummer-Korvenkontio M, Vaheri A. Clinical picture of nephropathia epidemica in children. Acta Paediatr 1994;83:526-9. (Pubitemid 24184262)
8. Lähdevirta J. Nephropathia epidemica. Ann Clin Res 1971;3(Suppl):1-154.
9. Makary P, Kanerva M, Ollgren J, Virtanen MJ, Vapalahti O, Lyytikäinen O. Disease burden of Puumala virus infections, 1995-2008. Epidemiol Infect 2010;138:1484-92.
10. Settergren B, Juto P, Trollfors B, Wadell G, Norrby SR. Clinical characteristics of nephropathia epidemica in Sweden: prospective study of 74 cases. Rev Infect Dis 1989;11:921-7.
11. Ahlm C, Lindén C, Linderholm M, Alexeyev OA, Billheden J, Elgh F, et al. Central nervous system and ophthalmic involvement in nephropathia epidemica (European type of haemorrhagic fever with renal syndrome). J Infect 1998;36:149-55. (Pubitemid 28165583)
12. Nuutinen H, Vuoristo M, Färkkilä M, Kahri A, Seppälä K, Valtonen V, et al. Hemorrhagic gastropathy in epidemic nephropathy. Gastrointest Endosc 1992;38:476-80.
13. Forslund T, Liisanantti R, Saijonmaa O, Fyhrquist F. Raised plasma endothelin-1 concentration in patients with nephropathia epidemica. Clin Nephrol 1993;40:69-73. (Pubitemid 23244624)
14. Mustonen J, Brummer-Korvenkontio M, Hedman K, Pasternack A, Pietilä K, Vaheri A. Nephropathia epidemica in Finland: a retrospective study of 126 cases. Scand J Infect Dis 1994;26:7-13. (Pubitemid 24073181)
15. Ala-Houhala I, Koskinen M, Ahola T, Harmoinen A, Kouri T, Laurila K, et al. Increased glomerular permeability in patients with nephropathia epidemica caused by Puumala hantavirus. Nephrol Dial Transplant 2002;7:246-52.
16. Mäkelä S. Determinants of clinical course and outcome of Puumala hantavirus-induced nephropathia epidemica. Thesis, Acta Universitatis Tamperensis 936. Tampere, Finland: Tampere University Press; 2003.
17. Rasche FM, Uhel B, Ulrich R, Krüger DH, Karges W, Czock D, et al. Thrombocytopenia and acute renal failure in Puumala hantavirus infections. Emerg Infect Dis 2004;10:1420-5. (Pubitemid 39014155)
18. Tiilikainen T, Jouppila P. Nephropathia epidemica during pregnancy. (In Finnish) Duodecim 1989;105:1916-9.
19. Forslund T, Saltevo J, Anttinen J, Auvinen S, Brummer- Korvenkontio M, Korhonen A, Poutiainen M. Complications of nephropathia epidemica: three cases. J Intern Med 1992;232:87-90.
20. Valtonen M, Kauppila M, Kotilainen P, Lähdevirta J, Svartbäck CM, Kosunen O, et al. Four fatal cases of nephropathia epidemica. Scand J Infect Dis 1995;27:515-7.
21. Takala A, Lähdevirta J, Jansson SE, Vapalahti O, Orpana A, Karonen SL, Repo H. Systematic inflammation in hemorrhagic fever with renal syndrome correlates with hypotension and thrombocytopenia but not with renal injury. J Infect Dis 2000;181:1964-70. (Pubitemid 30416158)
22. Mustonen J, Mäkelä S, Helin H, Helanterä A, Miettinen M, Partanen J, Pasternack A. Mesangiocapillary glomerulonephritis caused by Puumala hantavirus infection. Nephron 2001;89:402-7. (Pubitemid 33135819)
23. Hautala T, Sironen T, Vapalahti O, Pääkkö E, Särkioja T, Salmela P, et al. Hypophyseal hemorrhage and panhypopituitarism during Puumala virus infection: magnetic resonance imaging and detection of viral antigen in the hypophysis. Clin Infect Dis 2002;35:96-101. (Pubitemid 34666869)
24. Launes J, Hautanen A. Nephropathia epidemica encephalitis. Acta Neurol Scand 1988;78:234-5.
25. Kuusi T. Äkillinen likinäköisyys trombopeniaa ja proteinuriaa sairastavalla kuumepotilaalla. (In Finnish) Duodecim 1989;105:1220.
26. Partanen S, Kahanpää K, Peltola J, Lähdevirta J. Infection with the Puumala virus in pregnancy. Br J Obstet Gynaecol 1990;97:274-5. (Pubitemid 20158016)
27. Männistö J, Männistö T. Myyräk uumepleuriitti. (In Finnish) Duodecim 1994;110:1087-90.
28. Mustonen J, Baer M. Talvinen myyräkuume. (In Finnish) Duodecim 1996;112:2305-7.
29. Sane T, Färkkilä M. Hypopituitarismi ja hepatiitti myyräkuumeen komplikaationa. (In Finnish) Duodecim 2002;118: 457-61.
30. Toivanen AL, Valanne L, Tatlisumak T. Acute disseminated encephalomyelitis following nephropathia epidemica. Acta Neurol Scand 2002;105;333-6. (Pubitemid 34407241)
31. Mähönen SM, Sironen T, Vapalahti O, Pääkkö E, Hautala N, Ilonen J, et al. Puumala virus RNA in cerebrospinal fluid in a patient with uncomplicated nephropathia epidemica. J Clin Virol 2007;40:248-51. (Pubitemid 47552926)
32. Koolen MI, Jansen JL, Assmann KJ, Clement J, van Liebergen FJ. A sporadic case of acute hantavirus nephropathy in the Netherlands. Netherlands J Med 1989;35:25-32. (Pubitemid 19218008)
33. Esselink RA, Gerding MN, Brouwers PJ, Solleveld H, Jordans JG, Groen J, Osterhaus AD. Guillain-Barré syndrome associated with hantavirus infection. Lancet 1994;343:180-1. (Pubitemid 24028664)
34. Zeier M, Andrassy K, Zöller L, Ritz E. Hantavirus infection presenting as acute renal failure. Lancet 1990;336:1441-2.
35. Zeier M, Zöller L, Weinreich T, Padberg-Wolf E, Andrassy K, Ritz E. Severe hemorrhagic complications from infection with nephropathia epidemica strain of hantavirus. Clin Nephrol 1992;38:190-2.
36. Pilaski J, Feldmann H, Morzunov S, Rollin PE, Ruo SL, Lauer B, et al. Genetic identification of a new Puumala virus strain causing severe hemorrhagic fever with renal syndrome in Germany. J Infect Dis 1994;170:1456-62. (Pubitemid 24369905)
37. Dunst R, Mettang T, Kuhlmann U. Severe thrombocytopenia and response to corticosteroids in a case of nephropathia epidemica. Am J Kidney Dis 1998;31:116-20. (Pubitemid 28116692)
38. Bergman F, Krone B, Bleich S, Prange H, Paulus W. Encephalitis due to a hantavirus infection. J Infect 2002;45:58-64.
39. Foged N, Spencer ES, Andersen HK. Nephropathia epidemica. (In Danish) Ugeskr Laeger 1990;152:89-91.
40. Bennedbaek FN, Søe KL. Nephropathia epidemica. (In Danish) Ugeskr Laeger 1994;156:6392-3.
41. Linderholm M, Settergren B, Ahlm C, Burman LÅ, Träff U, Juto P. A Swedish fatal case of nephropathia epidemica. Scand J Infect Dis 1991;23:501-2.
42. Settergren B, Boman J, Linderholm M, Wiström M, Hägg E, Arvidsson PA. A case of nephropathia epidemica associated with panhypopituitarism and nephrotic syndrome. Nephron 1992;61:234-5.
43. Prebensen D. Nephropathia epidemica infection during first trimester of pregnancy - normal fetal outcome. Acta Obstet Gynecol Scand 1997;76:884-5. (Pubitemid 27429886)
44. Alexeyev OA, Baranov B. Puumala virus infection without signs of renal involvement. Scand J Infect Dis 1993;25:525-7. (Pubitemid 23268122)
45. Alexeyev OA, Morozov VG. Neurological manifestations of haemorrhagic fever with renal syndrome caused by Puumala virus: review of 811 cases. Clin Infect Dis 1995;20:255-8.
46. Silberberg L, Rollin PE, Kerouani G, Courdrier D. Haemorrhagic fever with renal syndrome and pregnancy: a case report. Trans R Soc Trop Med Hyg 1993;87:65.
47. Rabaud C, May T, Hoen B, Maignan M, Gérard A, Canton P. Guillain-Barré syndrome associated with hantavirus infection. Clin Infect Dis 1995;20:477-8.
48. Rebibou JM, Kiesterman JP, Cercueil JP, Tanter Y, Portier H, Rifle G, Chevet D. Papillary necrosis: a late complication of nephropathia epidemica. Clin Nephrol 1997;46:263-5. (Pubitemid 27462642)
49. Launay D, Thomas C, Fleury D, Roueff S, Line ML, Droz D, Vanhille P. Pulmonary-renal syndrome due to hemorrhagic fever with renal syndrome: an unusual manifestation of Puumala virus infection in France. Clin Nephrol 2003;59:297-300. (Pubitemid 36503550)
50. Papa A, Pliakogiannis T, Lundkvist Å. First case of Puumala virus infection in Greece. Infection 2000;28:334.
51. Caramello P, Canta F, Bonino L, Moiraghi C, Navone F, Lipani F, et al. Puumala virus pulmonary syndrome in a Romanian immigrant. J Travel Med 2002;9:326-9. (Pubitemid 35447336)
52. Finsterer J, Valentin A, Stöllberger C, Jankovic M, Prainer C. Puumala virus infection with multiorgan failure. Intensive Care Med 2003;29:501-2. (Pubitemid 36379460)
53. Krause R, Aberle S, Haberl R, Daxböc k F, Wenish C. Puumala virus infection with acute disseminated encephalomyelitis and multiorgan failure. Emerg Infect Dis 2003;9:603-5.
54. Hoier S, Aberle SW, Langner C, Schnedl W, Högenauer C, Reisinger EC, et al. Puumala virus RNA in patient with multiorgan failure. Emerg Infect Dis 2006;12:356-7.
55. Sivertsen HF, Mortensen L. En gravid kvinne med akutt nyresvikt. (In Norwegian) Tidskr Nor Laegerforen 2006;126:1612-3. (Pubitemid 43940957)
56. Lautala P, Uhari M. Epidemic nephropathy in children. Am J Dis Child 1991;145:1181-3.
57. Pirilä S. Skeittailijan kuume. (In Finnish) Duodecim 2005;121:2709-10.
58. Novo R, Gagnadoux MF, Guenno YL, Gubler MG, Niaudet P, Guyot C, Broyer M. Chronic renal failure after Puumala virus infection. Pediatr Nephrol 1999;13:934-5.
59. van der Werff J, Heyman P, Potters D, Peeters S, Cochez C, Piérard D. Hantavirus Puumala infection as a cause of fever of unknown origin in a child. Acta Paediatr 2004;93:1120-2. (Pubitemid 39452796)
60. Dusek J, Pejcoch M, Kolsky A, Seeman T, Nemec V, Stejskal J, et al. Mild course of Puumala nephropathy in children in an area with sporadic occurrence hantavirus infection. Pediatr Nephrol 2006;21:1889-92. (Pubitemid 44752479)
61. Armstrong LR, Bryan RT, Sarisky J, Khan AS, Rowe T, Ettestad PJ, et al. Mild hantaviral disease caused by Sin Nombre virus in a four year-old child. Pediatr Infect Dis J 1995;14:1108-10. (Pubitemid 26009710)
62. Hon KL, Leung CW, Cheng WT, Chan PK, Chu WC, Kwan YW, et al. Clinical presentation and outcome of severe acute respiratory syndrome in children. Lancet 2003;361:1701-3. (Pubitemid 36577444)
63. Giriputro S, Agus R, Sulastri S, Murniati D, Darwis F, Wiweka IB, et al. Clinical and epidemiological features of patients with confirmed avian influenza presenting to Suliati Sarose Infectious Diseases Hospital, Indonesia, 2006-2007. Ann Acad Med Singapore 2008;37:454-7.
64. Yoo KH, Choi Y; the Korean Pediatric Society. Haemorrhagic fever with renal syndrome in Korean children. Pediatr Nephrol 1994;8:540-4.
65. Takala A, Lähdevirta J, Jansson SE, Vapalahti O, Orpana A, Karonen SL, et al. Systemic inflammation in hemorrhagic fever with renal syndrome correlates with hypertension and thrombocytopenia but not with renal failure. J Infect Dis 2000;181:1964-70. (Pubitemid 30416158)
66. Mäkelä S, Mustonen J, Ala-Houhala I, Hurme M, Koivisto AM, Vaheri, et al. Urinary excretion of interleukin 6 correlates with proteinuria in acute Puumala hantavirus induced nephritis. Am J Kidney Dis 2004;43:809-16. (Pubitemid 38529618)
67. Temonen M, Mustonen J, Helin H, Pasternack A, Vaheri A, Holthöfer H. Cytokines, adhesion molecules and cellular infiltration in nephropathia epidemica kidneys: an immunohistochemical study. Clin Immunol Immunopathol 1996;78:47-55. (Pubitemid 26079195)
68. Linderholm M, Billström A, Settergren B, Tärnvik A. Pulmonary involvement in nephropathia epidemica as demonstrated by computer tomography. Infection 1992;20:263-6.