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Volumn 66, Issue 7, 2011, Pages 1481-1483

Prevalence of resistance mutations related to integrase inhibitor S/GSK1349572 in HIV-1 subtype B raltegravir-naive and -treated patients

Author keywords

Failure; Polymorphism; Prevalence

Indexed keywords

GSK1349572; INTEGRASE; INTEGRASE INHIBITOR; RALTEGRAVIR; UNCLASSIFIED DRUG;

EID: 79958857289     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr152     Document Type: Article
Times cited : (18)

References (9)
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    • Grinsztejn B, Nguyen BY, Katlama C et al. Protocol 005 Team. Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial. Lancet 2007; 369: 1261-9.
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    • Grinsztejn, B.1    Nguyen, B.Y.2    Katlama, C.3
  • 3
    • 77957956994 scopus 로고    scopus 로고
    • S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones
    • Abstract 555. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
    • Seki T, Kobayashi M, Wakasa-Morimoto C et al. S/GSK1349572 is a potent next generation HIV integrase inhibitor and demonstrates a superior resistance profile substantiated with 60 integrase mutant molecular clones. In: Abstracts of the Seventeenth Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, 2010. Abstract 555. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
    • (2010) Abstracts of the Seventeenth Conference on Retroviruses and Opportunistic Infections, San Francisco, CA
    • Seki, T.1    Kobayashi, M.2    Wakasa-Morimoto, C.3
  • 6
    • 79959249153 scopus 로고    scopus 로고
    • Activity of next generation integrase inhibitor (INI) S/GSK1349572 in subjects with HIV exhibiting raltegravir resistance: initial results of VIKING study (ING112961)
    • Abstract MOAB0105
    • Eron J, Durant J, Poizot-Martin I et al. Activity of next generation integrase inhibitor (INI) S/GSK1349572 in subjects with HIV exhibiting raltegravir resistance: initial results of VIKING study (ING112961). In: Abstracts of the Eighteenth International AIDS Conference, Vienna, Austria, 2010. Abstract MOAB0105.
    • (2010) Abstracts of the Eighteenth International AIDS Conference, Vienna, Austria
    • Eron, J.1    Durant, J.2    Poizot-Martin, I.3
  • 7
    • 65549085822 scopus 로고    scopus 로고
    • Characterization and structural analysis of HIV-1 integrase conservation
    • Ceccherini-Silberstein F, Malet I, D'Arrigo R et al. Characterization and structural analysis of HIV-1 integrase conservation. AIDS Rev 2009; 11: 17-29.
    • (2009) AIDS Rev , vol.11 , pp. 17-29
    • Ceccherini-Silberstein, F.1    Malet, I.2    D'Arrigo, R.3
  • 8
    • 42049119625 scopus 로고    scopus 로고
    • Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro
    • Malet I, Delelis O, Valantin MA et al. Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro. Antimicrob Agents Chemother 2008; 52: 1351-8.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1351-1358
    • Malet, I.1    Delelis, O.2    Valantin, M.A.3
  • 9
    • 79958860580 scopus 로고    scopus 로고
    • Polymorphisms at position 101 and 124 in the HIV-1 integrase (IN) gene: lack of effects on susceptibility to S/GSK1349572
    • Abstract H-935. American Society for Microbiology, Washington, DC, USA
    • Vavro C, Underwood M, Madsen H et al. Polymorphisms at position 101 and 124 in the HIV-1 integrase (IN) gene: lack of effects on susceptibility to S/GSK1349572. In: Abstracts of the Fiftieth Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, MA, 2010. Abstract H-935. American Society for Microbiology, Washington, DC, USA.
    • (2010) Abstracts of the Fiftieth Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, MA
    • Vavro, C.1    Underwood, M.2    Madsen, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.