메뉴 건너뛰기




Volumn 135, Issue 6, 2011, Pages 780-788

Modern concepts on the role of inflammation in pulmonary fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; BIOLOGICAL MARKER; CYTOKINE;

EID: 79958854110     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (82)

References (136)
  • 1
    • 0022655782 scopus 로고
    • A clinical, radiographic, and physiologic scoring system for the longitudinal assessment of patients with idiopathic pulmonary fibrosis
    • Watters LC, King TE, Schwarz MI, Waldron JA, Stanford RE, Cherniack RM. A clinical, radiographic, and physiologic scoring system for the longitudinal assessment of patients with idiopathic pulmonary fibrosis. Am Rev Respir Dis. 1986;133(1):97-103. (Pubitemid 16189105)
    • (1986) American Review of Respiratory Disease , vol.133 , Issue.1 , pp. 97-103
    • Watters, L.C.1    King, T.E.2    Schwarz, M.I.3
  • 2
    • 37549060070 scopus 로고    scopus 로고
    • Accelerated variant of idiopathic pulmonary fibrosis: Clinical behavior and gene expression pattern
    • Selman M, Carrillo G, Estrada A, et al. Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern. PLoS ONE. 2007;2(5):e482.
    • (2007) PLoS ONE , vol.2 , Issue.5
    • Selman, M.1    Carrillo, G.2    Estrada, A.3
  • 3
    • 0001500796 scopus 로고
    • The interstitial pneumonias
    • Simon M, Potchen EJ, LeMay M,. New York, NY: Grune & Stratton;
    • Liebow AA, Carrington CB. The interstitial pneumonias. In: Simon M, Potchen EJ, LeMay M, eds. Frontiers of Pulmonary Radiology. New York, NY: Grune & Stratton; 1969:102-141.
    • (1969) Frontiers of Pulmonary Radiology , pp. 102-141
    • Liebow, A.A.1    Carrington, C.B.2
  • 4
    • 0037080547 scopus 로고    scopus 로고
    • American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias
    • American Thoracic Society/European Respiratory Society international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am) Respir Crit Care Med. 2002;165(2):277-304.
    • (2002) Am Respir Crit Care Med. , vol.165 , Issue.2 , pp. 277-304
  • 5
    • 0020960174 scopus 로고
    • Bronchial lavage in inflammatory lung disease
    • Merrill WW, Reynolds HY. Bronchial lavage in inflammatory lung disease. Clin Chest Med. 1983;4(1):71-84. (Pubitemid 13095108)
    • (1983) Clinics in Chest Medicine , vol.4 , Issue.1 , pp. 71-84
    • Merrill, W.W.1    Reynolds, H.Y.2
  • 6
    • 12144256583 scopus 로고    scopus 로고
    • Lung inflammation and fibrosis: An alveolar macrophage-centered perspective from the 1970s to 1980s
    • DOI 10.1164/rccm.200406-788PP
    • Reynolds HY. Lung inflammation and fibrosis: an alveolar macrophagecentered perspective from the 1970s to 1980s. Am J Respir Crit Care Med. 2005; 171(2):98-102. (Pubitemid 40105406)
    • (2005) American Journal of Respiratory and Critical Care Medicine , vol.171 , Issue.2 , pp. 98-102
    • Reynolds, H.Y.1
  • 8
    • 9344223323 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: New insights into pathogenesis
    • DOI 10.1016/j.ccm.2004.04.003, PII S0272523104000474
    • Noble PW, Homer RJ. Idiopathic pulmonary fibrosis: new insights into pathogenesis. Clin Chest Med. 2004;25(4):749-758. (Pubitemid 39556507)
    • (2004) Clinics in Chest Medicine , vol.25 , Issue.4 SPEC.ISS. , pp. 749-758
    • Noble, P.W.1    Homer, R.J.2
  • 9
    • 9444285533 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Current trends in management
    • DOI 10.1016/j.ccm.2004.08.002, PII S0272523104000838
    • Raghu G, Chang J. Idiopathic pulmonary fibrosis: current trends in management. Clin Chest Med. 2004;25(4):621-636. (Pubitemid 39561702)
    • (2004) Clinics in Chest Medicine , vol.25 , Issue.4 SPEC.ISS. , pp. 621-636
    • Raghu, G.1    Chang, J.2
  • 10
    • 0035895243 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Prevailing and evolving hypotheses about its pathogenesis and implications for therapy
    • Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med. 2001;134(2):136-151. (Pubitemid 32096342)
    • (2001) Annals of Internal Medicine , vol.134 , Issue.2 , pp. 136-151
    • Selman, M.1    King Jr., T.E.2    Pardo, A.3
  • 11
    • 40949084762 scopus 로고    scopus 로고
    • Involvement of epithelial cell apoptosis in interstitial lung diseases
    • DOI 10.2169/internalmedicine.47.0713
    • Kuwano K. Involvement of epithelial cell apoptosis in interstitial lung diseases. Intern Med. 2008;47(5):345-353. (Pubitemid 351663683)
    • (2008) Internal Medicine , vol.47 , Issue.5 , pp. 345-353
    • Kuwano, K.1
  • 12
    • 0022135836 scopus 로고
    • Pathogenesis of "fibrosis" in interstitial pneumonia: An electron microscopic study
    • Katzenstein AL. Pathogenesis of "fibrosis" in interstitial pneumonia: an electron microscopic study. Hum Pathol. 1985;16001:1015-1024.
    • (1985) Hum Pathol. , vol.16 , Issue.10 , pp. 1015-1024
    • Katzenstein, A.L.1
  • 17
    • 0033870681 scopus 로고    scopus 로고
    • Soluble form of Fas and Fas ligand in BAL fluid from patients with pulmonary fibrosis and bronchiolitis obliterans organizing pneumonia
    • Kuwano K, Kawasaki M, Maeyama T, et al. Soluble form of fas and fas ligand in BAL fluid from patients with pulmonary fibrosis and bronchiolitis obliterans organizing pneumonia. Chest. 2000;118(2):451-458. (Pubitemid 30637815)
    • (2000) Chest , vol.118 , Issue.2 , pp. 451-458
    • Kuwano, K.1    Kawasaki, M.2    Maeyama, T.3    Hagimoto, N.4    Nakamura, N.5    Shirakawa, K.6    Hara, N.7
  • 19
    • 14344283933 scopus 로고    scopus 로고
    • Attenuation of bleomycininduced pneumopathy in mice by a caspase inhibitor. Am Physiol Lung Cell
    • Kuwano K, Kunitake R, Maeyama T, et al. Attenuation of bleomycininduced pneumopathy in mice by a caspase inhibitor. Am) Physiol Lung Cell Mol Physiol. 2001;280(2):L316-L325.
    • (2001) Mol Physiol. , vol.280 , Issue.2
    • Kuwano, K.1    Kunitake, R.2    Maeyama, T.3
  • 21
    • 0345707635 scopus 로고    scopus 로고
    • Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice
    • Li X, Rayford H, Uhal BD. Essential roles for angiotensin receptor AT1a in bleomycin-induced apoptosis and lung fibrosis in mice. Am J Pathol. 2003; 163(6):2523-2530. (Pubitemid 37466493)
    • (2003) American Journal of Pathology , vol.163 , Issue.6 , pp. 2523-2530
    • Li, X.1    Rayford, H.2    Uhal, B.D.3
  • 23
    • 76749165460 scopus 로고    scopus 로고
    • Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis
    • Sisson TH, Mendez M, Choi K, et al. Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am J Respir Crit Care Med. 2010; 181(3):254-263.
    • (2010) Am J Respir Crit Care Med. , vol.181 , Issue.3 , pp. 254-263
    • Sisson, T.H.1    Mendez, M.2    Choi, K.3
  • 24
    • 77951909085 scopus 로고    scopus 로고
    • Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease
    • Whitsett JA, Wert SE, Weaver TE. Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease. Annu Rev Med. 2010;61:105-119.
    • (2010) Annu Rev Med. , vol.61 , pp. 105-119
    • Whitsett, J.A.1    Wert, S.E.2    Weaver, T.E.3
  • 25
    • 48949119341 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: Association with altered surfactant protein processing and herpesvirus infection
    • Lawson WE, Crossno PF, Polosukhin W, et al. Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am J Physiol Lung Cell Mol Physiol. 2008;294(6):L1119-L1126.
    • (2008) Am J Physiol Lung Cell Mol Physiol. , vol.294 , Issue.6
    • Lawson, W.E.1    Crossno, P.F.2    Polosukhin, W.3
  • 26
    • 54049115076 scopus 로고    scopus 로고
    • Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis
    • Korfei M, Ruppert C, Mahavadi P, et al. Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2008;178(8):838-846.
    • (2008) Am J Respir Crit Care Med. , vol.178 , Issue.8 , pp. 838-846
    • Korfei, M.1    Ruppert, C.2    Mahavadi, P.3
  • 27
    • 79958865684 scopus 로고    scopus 로고
    • Gene expression profiles and immunohistochemical analysis highlight role of endoplasmic reticulum stress in pulmonary fibrosis
    • Chia JY, Jung Y, Liang J, et al. Gene expression profiles and immunohistochemical analysis highlight role of endoplasmic reticulum stress in pulmonary fibrosis. Am J Respir Crit Care Med. 2009;179:A2175.
    • (2009) Am J Respir Crit Care Med. , vol.179
    • Chia, J.Y.1    Jung, Y.2    Liang, J.3
  • 29
    • 34047188508 scopus 로고    scopus 로고
    • Telomerase mutations in families with idiopathic pulmonar/ fibrosis
    • Armanios MY, Chen JJ, Cogan JD, et al. Telomerase mutations in families with idiopathic pulmonar/ fibrosis. N Engl J Med. 2007;356(131:1317-1326.
    • (2007) N Engl J Med. , vol.356 , Issue.131 , pp. 1317-1326
    • Armanios, M.Y.1    Chen, J.J.2    Cogan, J.D.3
  • 30
    • 51349113450 scopus 로고    scopus 로고
    • Short telomeres are a risk factor for idiopathic pulmonary fibrosis
    • Alder JK, Chen JJ, Lancaster L, et al. Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci USA. 2008;105(351:13051- 13056.
    • (2008) Proc Natl Acad Sci USA. , vol.105 , Issue.351 , pp. 13051-13056
    • Alder, J.K.1    Chen, J.J.2    Lancaster, L.3
  • 31
    • 52749083873 scopus 로고    scopus 로고
    • Telomere shortening in familial and sporadic pulmonary fibrosis
    • Cronkhite JT, Xing C, Raghu G, et al. Telomere shortening in familial and sporadic pulmonary fibrosis. Am J Respir Crit Care Med. 2008;178(71:729-737.
    • (2008) Am J Respir Crit Care Med. , vol.178 , Issue.71 , pp. 729-737
    • Cronkhite, J.T.1    Xing, C.2    Raghu, G.3
  • 32
    • 42049109309 scopus 로고    scopus 로고
    • What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
    • DOI 10.1513/pats.200710-160DR
    • Strieter RM. What differentiates normal lung repair and fibrosis?: inflammation, resolution of repair, and fibrosis. Proc Am Thorac Soc. 2008; 5(3):305-310. (Pubitemid 351520676)
    • (2008) Proceedings of the American Thoracic Society , vol.5 , Issue.3 , pp. 305-310
    • Strieter, R.M.1
  • 33
    • 61749102618 scopus 로고    scopus 로고
    • Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis
    • Kim KK, Wei Y, Szekeres C, et al. Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosis. J Clin Invest. 2009;119(11:213-224.
    • (2009) J Clin Invest. , vol.119 , Issue.11 , pp. 213-224
    • Kim, K.K.1    Wei, Y.2    Szekeres, C.3
  • 35
    • 33746977705 scopus 로고    scopus 로고
    • Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis
    • Chilosi M, Zamo A, Doglioni C, et al. Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis. Respir Res. 2006;7:95.
    • (2006) Respir Res. , vol.7 , pp. 95
    • Chilosi, M.1    Zamo, A.2    Doglioni, C.3
  • 36
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-β1: Potential role in idiopathic pulmonary fibrosis
    • Willis BC, Liebler JM, Luby-Phelps K, et al. Induction of epithelialmesenchymal transition in alveolar epithelial cells by transforming growth factorbetal : potential role in idiopathic pulmonary fibrosis. Am J Pathol. 2005;166(5): 1321-1332. (Pubitemid 40586504)
    • (2005) American Journal of Pathology , vol.166 , Issue.5 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicholson, A.G.4    Crandall, E.D.5    Du, B.R.M.6    Borok, Z.7
  • 38
    • 70349441112 scopus 로고    scopus 로고
    • Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis
    • Tanjore H, Xu XC, Polosukhin W, et al. Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am J Respir Crit Care Med. 2009; 180(7):657-665.
    • (2009) Am J Respir Crit Care Med. , vol.180 , Issue.7 , pp. 657-665
    • Tanjore, H.1    Xu, X.C.2    Polosukhin, W.3
  • 40
    • 60649102339 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Pathogenesis, etiology and regulation
    • Wilson MS, Wynn TA. Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol. 2009;2(2):103-121.
    • (2009) Mucosal Immunol. , vol.2 , Issue.2 , pp. 103-121
    • Wilson, M.S.1    Wynn, T.A.2
  • 41
    • 33646195495 scopus 로고    scopus 로고
    • Regulation of fibrosis by the immune system
    • Lupher MLJ, Gallatin WM. Regulation of fibrosis by the immune system. Adv Immunol. 2006;89:245-288.
    • (2006) Adv Immunol. , vol.89 , pp. 245-288
    • Lupher, M.L.J.1    Gallatin, W.M.2
  • 42
    • 27744543102 scopus 로고    scopus 로고
    • Inflammatory cells during wound repair: The good, the bad and the ugly
    • DOI 10.1016/j.tcb.2005.09.002, PII S0962892405002278
    • Martin P, Leibovich SJ. Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol. 2005;15(11):599-607. (Pubitemid 41619424)
    • (2005) Trends in Cell Biology , vol.15 , Issue.11 , pp. 599-607
    • Martin, P.1    Leibovich, S.J.2
  • 43
    • 33846205929 scopus 로고    scopus 로고
    • T-Cell subsets: The more the merrier
    • DOI 10.1016/j.cub.2006.12.015, PII S0960982206026133
    • Weaver CT, Murphy KM. T-cell subsets: the more the merrier. Curr Biol. 2007;17(2):R61-R63. (Pubitemid 46107836)
    • (2007) Current Biology , vol.17 , Issue.2
    • Weaver, C.T.1    Murphy, K.M.2
  • 44
    • 0037213660 scopus 로고    scopus 로고
    • Granulomas in schistosome and mycobacterial infections: A model of local immune responses
    • DOI 10.1016/S1471-4906(02)00006-6, PII S1471490602000066
    • Sandor M, Weinstock JV, Wynn TA. Granulomas in schistosome and mycobacterial infections: a model of local immune responses. Trends Immunol. 2003,24(1):44-52. (Pubitemid 35462112)
    • (2003) Trends in Immunology , vol.24 , Issue.1 , pp. 44-52
    • Sandor, M.1    Weinstock, J.V.2    Wynn, T.A.3
  • 47
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8(12):958-969.
    • (2008) Nat Rev Immunol. , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 48
    • 77349089236 scopus 로고    scopus 로고
    • Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation
    • Dominguez PM, Ardavin C. Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation. Immunol Rev. 2010;234(1):90-104.
    • (2010) Immunol Rev. , vol.234 , Issue.1 , pp. 90-104
    • Dominguez, P.M.1    Ardavin, C.2
  • 49
    • 3543107212 scopus 로고    scopus 로고
    • Fibrotic disease and the T(H)1/T(H)2 paradigm
    • Wynn TA. Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol. 2004;4(8):583-594.
    • (2004) Nat Rev Immunol. , vol.4 , Issue.8 , pp. 583-594
    • Wynn, T.A.1
  • 52
    • 79958863210 scopus 로고    scopus 로고
    • The inflammatory macrophage: A story of Jekyll and Hyde
    • Duffield JS. The inflammatory macrophage: a story of Jekyll and Hyde. Clin Sci (Lond). 2003;10(2):137-142.
    • (2003) Clin Sci (Lond). , vol.10 , Issue.2 , pp. 137-142
    • Duffield, J.S.1
  • 54
    • 3142659551 scopus 로고    scopus 로고
    • Interleukin-13 in asthma pathogenesis
    • Wills-Karp M. Interleukin-13 in asthma pathogenesis. Curr Allergy Asthma Rep. 2004;4(2):123-131. (Pubitemid 38906753)
    • (2004) Current Allergy and Asthma Reports , vol.4 , Issue.2 , pp. 123-131
    • Wills-Karp, M.1
  • 55
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu Z, Homer RJ, Wang Z, et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999; 103(61:779-788.
    • (1999) J Clin Invest , vol.103 , Issue.61 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3
  • 56
    • 0036426634 scopus 로고    scopus 로고
    • Tetracycline-controlled transcriptional regulation systems: Advances and application in transgenic animal modeling
    • DOI 10.1016/S1084-9521(02)00018-6
    • Zhu Z, Zheng T, Lee CG, Homer RJ, Elias JA. Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling. Semin Cell Dev Biol. 2002;13(2):121-128. (Pubitemid 35300824)
    • (2002) Seminars in Cell and Developmental Biology , vol.13 , Issue.2 , pp. 121-128
    • Zhu, Z.1    Zheng, T.2    Lee, C.G.3    Homer, R.J.4    Elias, J.A.5
  • 59
    • 0033761127 scopus 로고    scopus 로고
    • Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- And cathepsin-dependent emphysema
    • Zheng T, Zhu Z, Wang Z, et al. Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest. 2000;106(9):1081-1093.
    • (2000) J Clin Invest. , vol.106 , Issue.9 , pp. 1081-1093
    • Zheng, T.1    Zhu, Z.2    Wang, Z.3
  • 61
    • 0037087365 scopus 로고    scopus 로고
    • IL-13-induced chemokine responses in the lung: Role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling
    • Zhu Z, Ma B, Zheng T, et al. IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2002;168(6):2953-2962. (Pubitemid 34211676)
    • (2002) Journal of Immunology , vol.168 , Issue.6 , pp. 2953-2962
    • Zhu, Z.1    Ma, B.2    Zheng, T.3    Homer, R.J.4    Lee, C.G.5    Charo, I.F.6    Noble, P.7    Elias, J.A.8
  • 64
    • 65249093099 scopus 로고    scopus 로고
    • Fibrocytes as potential biomarkers in idiopathic pulmonary fibrosis
    • Moore BB. Fibrocytes as potential biomarkers in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2009;179(7):524-525.
    • (2009) Am J Respir Crit Care Med. , vol.179 , Issue.7 , pp. 524-525
    • Moore, B.B.1
  • 65
    • 1642566536 scopus 로고    scopus 로고
    • The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-Induced inflammation and remodeling
    • Ma B, Zhu Z, Homer RJ, Gerard C, Strieter R, Elias JA. The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2004;172(3):1872-1881. (Pubitemid 38116837)
    • (2004) Journal of Immunology , vol.172 , Issue.3 , pp. 1872-1881
    • Ma, B.1    Zhu, Z.2    Homer, R.J.3    Gerard, C.4    Strieter, R.5    Elias, J.A.6
  • 66
    • 33645796414 scopus 로고    scopus 로고
    • Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling
    • Ma B, Liu W, Homer RJ, et al. Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2006,-176(8):4968-4978.
    • (2006) J Immunol. , vol.176 , Issue.8 , pp. 4968-4978
    • Ma, B.1    Liu, W.2    Homer, R.J.3
  • 67
    • 57349151546 scopus 로고    scopus 로고
    • Endogenous IL-11 signaling is essential in Th2- And IL-13-induced inflammation and mucus production
    • Lee CG, Hartl D, Matsuura H, et al. Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production. Am J Respir Cell Mol Biol. 2008;39(6):739-746.
    • (2008) Am J Respir Cell Mol Biol. , vol.39 , Issue.6 , pp. 739-746
    • Lee, C.G.1    Hartl, D.2    Matsuura, H.3
  • 68
    • 34249798763 scopus 로고    scopus 로고
    • Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling
    • DOI 10.2353/ajpath.2006.060617
    • Fulkerson PC, Fischetti CA, Rothenberg ME. Eosinophils and CCR3 regulate interleukin-13 transgene-induced pulmonary remodeling. Am J Pathol. 2006;169(6):2117-2126. (Pubitemid 351181971)
    • (2006) American Journal of Pathology , vol.169 , Issue.6 , pp. 2117-2126
    • Fulkerson, P.C.1    Fischetti, C.A.2    Rothenberg, M.E.3
  • 69
    • 0037406923 scopus 로고    scopus 로고
    • Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- And Th2-type pulmonary granuloma fibroblasts
    • Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM. Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts. Am) Pathol. 2003;162(5):1475-1486.
    • (2003) Am Pathol. , vol.162 , Issue.5 , pp. 1475-1486
    • Jakubzick, C.1    Choi, E.S.2    Kunkel, S.L.3    Joshi, B.H.4    Puri, R.K.5    Hogaboam, C.M.6
  • 71
    • 0042388120 scopus 로고    scopus 로고
    • Adenosine mediates IL-13induced inflammation and remodeling in the lung and interacts in an IL-13adenosine amplification pathway
    • Blackburn MR, Lee CG, Young HW, et al. Adenosine mediates IL-13induced inflammation and remodeling in the lung and interacts in an IL-13adenosine amplification pathway. J Clin Invest. 2003;112(31:332-344.
    • (2003) J Clin Invest. , vol.112 , Issue.31 , pp. 332-344
    • Blackburn, M.R.1    Lee, C.G.2    Young, H.W.3
  • 74
    • 58149306389 scopus 로고    scopus 로고
    • Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model
    • Shimamura T, Fujisawa T, Husain SR, Kioi M, Nakajima A, Puri RK. Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 2008; 181(7):4656-4665.
    • (2008) J Immunol. , vol.181 , Issue.7 , pp. 4656-4665
    • Shimamura, T.1    Fujisawa, T.2    Husain, S.R.3    Kioi, M.4    Nakajima, A.5    Puri, R.K.6
  • 75
    • 57249094020 scopus 로고    scopus 로고
    • IL13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis
    • Fichtner-Feigl S, Young CA, Kitani A, Geissler EK, Schlitt HJ, Strober W. IL13 signaling via IL-13R alpha2 induces major downstream fibrogenic factors mediating fibrosis in chronic TNBS colitis. Gastroenterology. 2008;135(6):2003-2013.
    • (2008) Gastroenterology. , vol.135 , Issue.6 , pp. 2003-2013
    • Fichtner-Feigl, S.1    Young, C.A.2    Kitani, A.3    Geissler, E.K.4    Schlitt, H.J.5    Strober, W.6
  • 77
    • 0036787916 scopus 로고    scopus 로고
    • Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis
    • Belperio JA, Dy M, Burdick MD, et al. Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol. 2002;27(4):419-427.
    • (2002) Am J Respir Cell Mol Biol. , vol.27 , Issue.4 , pp. 419-427
    • Belperio, J.A.1    Dy, M.2    Burdick, M.D.3
  • 78
    • 30044449492 scopus 로고    scopus 로고
    • 1 production and fibrosis
    • DOI 10.1038/nm1332
    • Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A. IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat Med. 2006;12(1):99-106. (Pubitemid 43050083)
    • (2006) Nature Medicine , vol.12 , Issue.1 , pp. 99-106
    • Fichtner-Feigl, S.1    Strober, W.2    Kawakami, K.3    Puri, R.K.4    Kitani, A.5
  • 81
    • 77949516122 scopus 로고    scopus 로고
    • Bleomycin and IL-I betamediated pulmonar/ fibrosis is IL-17A dependent
    • Wilson MS, Madala SK, Ramalingam TR, et al. Bleomycin and IL-I betamediated pulmonar/ fibrosis is IL-17A dependent. J Exp Med. 2010;207(3):535-552.
    • (2010) J Exp Med. , vol.207 , Issue.3 , pp. 535-552
    • Wilson, M.S.1    Madala, S.K.2    Ramalingam, T.R.3
  • 84
    • 77950379862 scopus 로고    scopus 로고
    • Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages
    • Murray LA, Rosada R, Moreira AP, et al. Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages. PLoS One. 2010;5(3):e9683.
    • (2010) PLoS One. , vol.5 , Issue.3
    • Murray, L.A.1    Rosada, R.2    Moreira, A.P.3
  • 85
    • 0029113474 scopus 로고
    • A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA)
    • Wallace WA, Ramage EA, Lamb D, Howie SE. A type 2 (Th2-like) pattern of immune response predominates in the pulmonary interstitium of patients with cryptogenic fibrosing alveolitis (CFA). Clin Exp Immunol. 1995;101(3):436-441.
    • (1995) Clin Exp Immunol. , vol.101 , Issue.3 , pp. 436-441
    • Wallace, W.A.1    Ramage, E.A.2    Lamb, D.3    Howie, S.E.4
  • 86
    • 2442665761 scopus 로고    scopus 로고
    • Evaluation of interleukin-13 in the serum and bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis [in Chinese]
    • Xiao L, Li ZH, Hou XM, Yu RJ. Evaluation of interleukin-13 in the serum and bronchoalveolar lavage fluid of patients with idiopathic pulmonary fibrosis [in Chinese]. Zhongbua lie He He Hu Xi Za Zhi 2003;26(11):686-688.
    • (2003) Zhongbua Lie He He Hu Xi Za Zhi , vol.26 , Issue.11 , pp. 686-688
    • Xiao, L.1    Li, Z.H.2    Hou, X.M.3    Yu, R.J.4
  • 87
    • 0033021135 scopus 로고    scopus 로고
    • Immunoreactive interleukin 4 and interferon-γ expression by type II alveolar epithelial cells in interstitial lung disease
    • DOI 10.1002/(SICI)1096-9896(199903)187:4<475::AID-PATH268>3.0.CO;2- N
    • Wallace WA, Howie SE. Immunoreactive interleukin 4 and interferongamma expression by type Il alveolar epithelial cells in interstitial lung disease. J Pathol. 1999;187(4):475-480. (Pubitemid 29118281)
    • (1999) Journal of Pathology , vol.187 , Issue.4 , pp. 475-480
    • Wallace, W.A.H.1    Howie, S.E.M.2
  • 88
    • 0031606459 scopus 로고    scopus 로고
    • Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung
    • Hancock A, Armstrong L, Gama R, Millar A. Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung. Am J Respir Cell Mol Biol. 1998;18(1):60-65.
    • (1998) Am J Respir Cell Mol Biol. , vol.18 , Issue.1 , pp. 60-65
    • Hancock, A.1    Armstrong, L.2    Gama, R.3    Millar, A.4
  • 89
    • 53149112751 scopus 로고    scopus 로고
    • Assessment of gene transcription demonstrates connection with the clinical course of idiopathic interstitial pneumonia
    • Golee M, Lambers C, Hofbauer E, et al. Assessment of gene transcription demonstrates connection with the clinical course of idiopathic interstitial pneumonia. Respiration. 2008;76(3):261-269.
    • (2008) Respiration. , vol.76 , Issue.3 , pp. 261-269
    • Golee, M.1    Lambers, C.2    Hofbauer, E.3
  • 90
    • 33745036694 scopus 로고    scopus 로고
    • Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system
    • DOI 10.1084/jem.20052448
    • Voehringer D, Reese TA, Huang X, Shinkai K, Locksley RM. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J Exp Med. 2006;203(6):1435-1446. (Pubitemid 43877606)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.6 , pp. 1435-1446
    • Voehringer, D.1    Reese, T.A.2    Huang, X.3    Shinkai, K.4    Locksley, R.M.5
  • 92
    • 33646753396 scopus 로고    scopus 로고
    • Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells
    • Arora M, Chen L, Paglia M, et al. Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells. Proc Natl Acad Sci USA. 2006;103(20):7777-7782.
    • (2006) Proc Natl Acad Sci USA. , vol.103 , Issue.20 , pp. 7777-7782
    • Arora, M.1    Chen, L.2    Paglia, M.3
  • 93
    • 33845905754 scopus 로고    scopus 로고
    • IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells
    • Temann UA, Laouar Y, Eynon EE, Homer R, Flavell RA. IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells. Int Immunol. 2007;1901:1-10.
    • (2007) Int Immunol. , vol.1901 , pp. 1-10
    • Temann, U.A.1    Laouar, Y.2    Eynon, E.E.3    Homer, R.4    Flavell, R.A.5
  • 95
    • 30844450369 scopus 로고    scopus 로고
    • Stimulation of toll-like receptor 2 with bleomycin results in cellular activation and secretion of pro-inflammatory cytokines and chemokines
    • DOI 10.1016/j.taap.2005.05.002, PII S0041008X05002139
    • Razonable RR, Henault M, Paya CV. Stimulation of toll-like receptor 2 with bleomycin results in cellular activation and secretion of pro-inflammatory cytokines and chemokines. Toxicol Appl Pharmacol. 2006;210(3):181-189. (Pubitemid 43107561)
    • (2006) Toxicology and Applied Pharmacology , vol.210 , Issue.3 , pp. 181-189
    • Razonable, R.R.1    Henault, M.2    Paya, C.V.3
  • 96
    • 1342324768 scopus 로고    scopus 로고
    • Cutting Edge: Activation of Toll-Like Receptor 2 Induces a Th2 Immune Response and Promotes Experimental Asthma
    • Redecke V, Hacker H, Datta SK, et al. Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Immunol. 2004;172(5):2739-2743. (Pubitemid 38263655)
    • (2004) Journal of Immunology , vol.172 , Issue.5 , pp. 2739-2743
    • Redecke, V.1    Hacker, H.2    Datta, S.K.3    Fermin, A.4    Pitha, P.M.5    Broide, D.H.6    Raz, E.7
  • 97
    • 11444270348 scopus 로고    scopus 로고
    • Upregulation of interleukin-13 and its receptor in a murine model of bleomycin-induced scleroderma
    • DOI 10.1159/000082331
    • Matsushita M, Yamamoto T, Nishioka K. Upregulation of interleukin-13 and its receptor in a murine model of bleomycin-induced scleroderma. Int Arch Allergy Immunol. 2004;135(4):348-356. (Pubitemid 40082202)
    • (2004) International Archives of Allergy and Immunology , vol.135 , Issue.4 , pp. 348-356
    • Matsushita, M.1    Yamamoto, T.2    Nishioka, K.3
  • 98
    • 33847377509 scopus 로고    scopus 로고
    • Increased bleomycin-induced skin fibrosis in mice lacking the Th1-specific transcription factor T-bet
    • DOI 10.1159/000098208
    • Lakos G, Melichian D, Wu M, Varga J. Increased bleomycin-induced skin fibrosis in mice lacking the ThI-specific transcription factor T-bet. Pathobiology. 2006;73(5):224-237. (Pubitemid 46332830)
    • (2006) Pathobiology , vol.73 , Issue.5 , pp. 224-237
    • Lakos, G.1    Melichian, D.2    Wu, M.3    Varga, J.4
  • 100
    • 58749091674 scopus 로고    scopus 로고
    • Untangling the complex web of IL-4- And IL-13-mediated signaling pathways
    • Wills-Karp M, Finkelman FD. Untangling the complex web of IL-4- and IL-13-mediated signaling pathways. Sci Signal. 2008;1(51):pe55.
    • (2008) Sci Signal. , vol.1 , Issue.51
    • Wills-Karp, M.1    Finkelman, F.D.2
  • 104
    • 48949117336 scopus 로고    scopus 로고
    • Hyper-responsiveness of IPF/ UIP fibroblasts: Interplay between TGFbetal, IL-13 and CCL2
    • Murray LA, Argentieri RL, Farrell FX, et al. Hyper-responsiveness of IPF/ UIP fibroblasts: interplay between TGFbetal, IL-13 and CCL2. Int J Biochem Cell Biol. 2008;40(10):2174-2182.
    • (2008) Int J Biochem Cell Biol. , vol.40 , Issue.10 , pp. 2174-2182
    • Murray, L.A.1    Argentieri, R.L.2    Farrell, F.X.3
  • 105
    • 0034800653 scopus 로고    scopus 로고
    • CCLI8/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis
    • Pardo A, Smith KM, Abrams J, et al. CCLI8/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis. J Leukoc Biol. 2001;70(4):610-616.
    • (2001) J Leukoc Biol. , vol.70 , Issue.4 , pp. 610-616
    • Pardo, A.1    Smith, K.M.2    Abrams, J.3
  • 106
    • 22144451076 scopus 로고    scopus 로고
    • Involvement of CC chemokine ligand 18 (CCLI 8) in normal and pathological processes
    • Schutyser E, Richmond A, Van Damme J. Involvement of CC chemokine ligand 18 (CCLI 8) in normal and pathological processes. J Leukoc Biol. 2005; 78(11:14-26.
    • (2005) J Leukoc Biol. , vol.78 , Issue.11 , pp. 14-26
    • Schutyser, E.1    Richmond, A.2    Van Damme, J.3
  • 107
    • 25444500667 scopus 로고    scopus 로고
    • Serum pulmonary and activation-regulated chemokine/CCL18 levels in patients with systemic sclerosis: A sensitive indicator of active pulmonary fibrosis
    • DOI 10.1002/art.21257
    • Kodera M, Hasegawa M, Komura K, Yanaba K, Takehara K, Sato S. Serum pulmonary and activation-regulated chemokine/CCL18 levels in patients with systemic sclerosis: a sensitive indicator of active pulmonary fibrosis. Arthritis Rheum. 2005;52(9):2889-2896. (Pubitemid 41369120)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.9 , pp. 2889-2896
    • Kodera, M.1    Hasegawa, M.2    Komura, K.3    Yanaba, K.4    Takehara, K.5    Sato, S.6
  • 108
    • 33645307685 scopus 로고    scopus 로고
    • A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18
    • Prasse A, Pechkovsky DV, Toews GB, et al. A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. Am I Respir Crit Care Med. 2006;173(7):781-792.
    • (2006) Am i Respir Crit Care Med. , vol.173 , Issue.7 , pp. 781-792
    • Prasse, A.1    Pechkovsky, D.V.2    Toews, G.B.3
  • 110
    • 65249160219 scopus 로고    scopus 로고
    • Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis
    • Prasse A, Probst C, Bargagli E, et al. Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 2009;179(8):717-723.
    • (2009) Am J Respir Crit Care Med. , vol.179 , Issue.8 , pp. 717-723
    • Prasse, A.1    Probst, C.2    Bargagli, E.3
  • 111
    • 77954602335 scopus 로고    scopus 로고
    • Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype
    • Mathai SK, Gulati M, Peng X, et al. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab Invest. 2010;90(6):812-823.
    • (2010) Lab Invest. , vol.90 , Issue.6 , pp. 812-823
    • Mathai, S.K.1    Gulati, M.2    Peng, X.3
  • 113
    • 69249150516 scopus 로고    scopus 로고
    • T-helper type 2-driven inflammation defines major subphenotypes of asthma
    • Woodruff PG, Modrek B, Choy DF, et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med. 2009;180(5):388-395.
    • (2009) Am J Respir Crit Care Med. , vol.180 , Issue.5 , pp. 388-395
    • Woodruff, P.G.1    Modrek, B.2    Choy, D.F.3
  • 114
    • 79958827621 scopus 로고    scopus 로고
    • Peripheral biomarkers of an IL-13 induced bronchial epithelial gene signature in asthma
    • Poster presented at: January 18-20, Keystone, CO.
    • Jia G, Modrek B, Choy DF, Abbas AR, Woodruff PG, Fahy JV. Peripheral biomarkers of an IL-13 induced bronchial epithelial gene signature in asthma. Poster presented at: Asthma and Allergy Keystone Symposium; January 18-20, 2009; Keystone, CO.
    • (2009) Asthma and Allergy Keystone Symposium
    • Jia, G.1    Modrek, B.2    Choy, D.F.3    Abbas, A.R.4    Woodruff, P.G.5    Fahy, J.V.6
  • 115
    • 49949114547 scopus 로고    scopus 로고
    • Molecular subsets in the gene expression signatures of scleroderma skin
    • Milano A, Pendergrass SA, Sargent JL, et al. Molecular subsets in the gene expression signatures of scleroderma skin. PLoS One. 2008;3(7):e2696.
    • (2008) PLoS One. , vol.3 , Issue.7
    • Milano, A.1    Pendergrass, S.A.2    Sargent, J.L.3
  • 116
    • 76649115304 scopus 로고    scopus 로고
    • A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity
    • Sargent JL, Milano A, Bhattacharyya S, et al. A TGFbeta-responsive gene signature is associated with a subset of diffuse scleroderma with increased disease severity. J Invest Dermatol. 2010; 130(31:694-705.
    • (2010) J Invest Dermatol. , vol.130 , Issue.31 , pp. 694-705
    • Sargent, J.L.1    Milano, A.2    Bhattacharyya, S.3
  • 117
    • 0025984699 scopus 로고
    • The role of TGF-beta in pulmonary fibrosis
    • Khalil N, Greenberg AH. The role of TGF-beta in pulmonary fibrosis. Ciba Found Symp. 1991;157:194-207.
    • (1991) Ciba Found Symp. , vol.157 , pp. 194-207
    • Khalil, N.1    Greenberg, A.H.2
  • 118
    • 0029995587 scopus 로고    scopus 로고
    • Transforming growth factor-β1-deficient mice: Identification of isoform-specific activities in vivo
    • Letterio JJ, Roberts AB. Transforming growth factor-betal -deficient mice: identification of isoform-specific activities in vivo. J Leukoc Biol. 1996;59(6): 769-774. (Pubitemid 26238470)
    • (1996) Journal of Leukocyte Biology , vol.59 , Issue.6 , pp. 769-774
    • Letterio, J.J.1    Roberts, A.B.2
  • 119
    • 0035903306 scopus 로고    scopus 로고
    • Lnterleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1)
    • Lee CG, Homer RJ, Zhu Z, et al. lnterleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med. 2001,-194(6):809-821.
    • (2001) J Exp Med. , vol.194 , Issue.6 , pp. 809-821
    • Lee, C.G.1    Homer, R.J.2    Zhu, Z.3
  • 122
    • 34147099468 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-betal stimulates pulmonary fibrosis and inflammation via a Baxdependent, bid-activated pathway that involves matrix metalloproteinase-12
    • Kang HR, Cho SJ, Lee CG, Homer RJ, Elias JA. Transforming growth factor (TGF)-betal stimulates pulmonary fibrosis and inflammation via a Baxdependent, bid-activated pathway that involves matrix metalloproteinase-12. J Biol Chem. 2007;282(101:7723-7732.
    • (2007) J Biol Chem. , vol.282 , Issue.101 , pp. 7723-7732
    • Kang, H.R.1    Cho, S.J.2    Lee, C.G.3    Homer, R.J.4    Elias, J.A.5
  • 125
    • 0034606218 scopus 로고    scopus 로고
    • Interferon gamma induction of pulmonary emphysema in the adult murine lung
    • Wang Z, Zheng T, Zhu Z, et al. Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med. 2000;192(11):1587-1600.
    • (2000) J Exp Med. , vol.192 , Issue.11 , pp. 1587-1600
    • Wang, Z.1    Zheng, T.2    Zhu, Z.3
  • 126
    • 38449120549 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13J
    • Chapoval SP, Al-Garawi A, Lora JM, et al. Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13J Immunol. 2007;179(10): 7030-7041.
    • (2007) Immunol. , vol.179 , Issue.10 , pp. 7030-7041
    • Chapoval, S.P.1    Al-Garawi, A.2    Lora, J.M.3
  • 128
    • 66049139534 scopus 로고    scopus 로고
    • Role of breast regression protein 39 (BRP39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis
    • Lee CG, Hartl D, Lee GR, et al. Role of breast regression protein 39 (BRP39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med. 2009;206(5):1149-1166.
    • (2009) J Exp Med. , vol.206 , Issue.5 , pp. 1149-1166
    • Lee, C.G.1    Hartl, D.2    Lee, G.R.3
  • 129
    • 51249120776 scopus 로고    scopus 로고
    • Identification of transforming growth factor betai -driven genetic programs of acute lung fibrosis
    • Pulichino AM, Wang IM, Caron A, et al. Identification of transforming growth factor betai -driven genetic programs of acute lung fibrosis. Am J Respir Cell Mol Biol. 2008;39(3):324-336.
    • (2008) Am J Respir Cell Mol Biol. , vol.39 , Issue.3 , pp. 324-336
    • Pulichino, A.M.1    Wang, I.M.2    Caron, A.3
  • 131
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-β, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGFbeta, PGE2, and PAF. J Clin Invest. 1998;101 (4):890-898. (Pubitemid 28096086)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.4 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 132
    • 44449101196 scopus 로고    scopus 로고
    • Macrophages produce TGF-betainduced (beta-ig-h3) following ingestion of apoptotic cells and regulate MMPI4 levels and collagen turnover in fibroblasts
    • Nacu N, Luzina IG, Highsmith K, et al. Macrophages produce TGF-betainduced (beta-ig-h3) following ingestion of apoptotic cells and regulate MMPI4 levels and collagen turnover in fibroblasts. J Immunol. 2008; 180(71:5036-5044.
    • (2008) J Immunol. , vol.180 , Issue.71 , pp. 5036-5044
    • Nacu, N.1    Luzina, I.G.2    Highsmith, K.3
  • 133
    • 60549103394 scopus 로고    scopus 로고
    • Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling
    • Medeiros Al, Serezani CH, Lee SP, Peters-Golden M. Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling.; Exp Med. 2009;20601:61-68.
    • (2009) Exp Med. , vol.206 , Issue.1 , pp. 61-68
    • Medeiros, A.L.1    Serezani, C.H.2    Lee, S.P.3    Peters-Golden, M.4
  • 134
    • 77950366886 scopus 로고    scopus 로고
    • Decoding cell death signals in inflammation and immunity
    • Zitvogel L, Kepp O, Kroemer G. Decoding cell death signals in inflammation and immunity. Cell. 2010;140(6):798-804.
    • (2010) Cell. , vol.140 , Issue.6 , pp. 798-804
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3
  • 135
    • 45549109370 scopus 로고    scopus 로고
    • Activation of a TGFbeta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II
    • Gratchev A, Kzhyshkowska J, Kannookadan S, et al. Activation of a TGFbeta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II. J Immunol. 2008;180(101:6553-6565.
    • (2008) J Immunol. , vol.180 , Issue.101 , pp. 6553-6565
    • Gratchev, A.1    Kzhyshkowska, J.2    Kannookadan, S.3
  • 136
    • 67650349068 scopus 로고    scopus 로고
    • Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): A multicentre, randomised, placebo-controlled trial
    • King TEJ, Albera C, Bradford WZ, et al. Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial. Lancet. 2009;374(9685):222- 228.
    • (2009) Lancet. , vol.374 , Issue.9685 , pp. 222-228
    • King, T.E.J.1    Albera, C.2    Bradford, W.Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.