메뉴 건너뛰기




Volumn 89, Issue 5, 2011, Pages 345-354

Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats

Author keywords

Bmpr2; Cgki cyrillic; Endothelial apoptosis; Fluoxetine; Monocrotaline; Pulmonary arterial hypertension; Remodeling; Serotonin transporter; Ukrainian

Indexed keywords

BETA CATENIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CASPASE 3; CYCLIC GMP; FLUOXETINE; MONOCROTALINE; SMAD1 PROTEIN;

EID: 79958846644     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/y11-024     Document Type: Article
Times cited : (7)

References (44)
  • 1
    • 77249149939 scopus 로고    scopus 로고
    • BMP2 promotes differentiation of nitrergic and catecholaminergic enteric neurons through a Smad1- dependent pathway
    • doi:10.1152/ajpgi.00343.2009. PMID: 20007850
    • Anitha, M., Shahnavaz, N., Qayed, E., Joseph, I., Gossrau, G., Mwangi, S., et al. 2010. BMP2 promotes differentiation of nitrergic and catecholaminergic enteric neurons through a Smad1- dependent pathway. Am. J. Physiol. Gastrointest. Liver Physiol. 298(3): G375-G383. doi:10.1152/ajpgi.00343.2009. PMID: 20007850.
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol , vol.298 , Issue.3 , pp. 375-383
    • Anitha, M.1    Shahnavaz, N.2    Qayed, E.3    Joseph, I.4    Gossrau, G.5    Mwangi, S.6
  • 2
    • 17044369273 scopus 로고    scopus 로고
    • Generation of a floxed allele of the mouse BMP type II receptor gene
    • doi:10.1002/gene.20099, PMID:15736264
    • Beppu, H., Lei, H., Bloch, K.D., and Li, E. 2005. Generation of a floxed allele of the mouse BMP type II receptor gene. Genesis, 41(3): 133-137. doi:10.1002/gene.20099. PMID:15736264.
    • (2005) Genesis , vol.41 , Issue.3 , pp. 133-137
    • Beppu, H.1    Lei, H.2    Bloch, K.D.3    Li, E.4
  • 3
    • 70349211744 scopus 로고    scopus 로고
    • Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/ PDGFR pathway
    • doi:10.1172/JCI38079, PMID:19690384
    • Cohen, E.D., Ihida-Stansbury, K., Lu, M.M., Panettieri, R.A., Jones, P.L., and Morrisey, E.E. 2009. Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/ PDGFR pathway. J. Clin. Invest. 119(9): 2538-2549. doi:10.1172/JCI38079. PMID:19690384.
    • (2009) J. Clin. Invest , vol.119 , Issue.9 , pp. 2538-2549
    • Cohen, E.D.1    Ihida-Stansbury, K.2    Lu, M.M.3    Panettieri, R.A.4    Jones, P.L.5    Morrisey, E.E.6
  • 4
    • 66749129603 scopus 로고    scopus 로고
    • Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene
    • doi:10.1186/ 1471-2466-9-19. PMID:19426553
    • Crona, D., Harral, J., Adnot, S., Eddahibi, S., and West, J. 2009. Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene. BMC Pulm. Med. 9(1): 19-25. doi:10.1186/ 1471-2466-9-19. PMID:19426553.
    • (2009) BMC Pulm. Med , vol.9 , Issue.1 , pp. 19-25
    • Crona, D.1    Harral, J.2    Adnot, S.3    Eddahibi, S.4    West, J.5
  • 5
    • 57349188499 scopus 로고    scopus 로고
    • Molecular mechanisms of pulmonary arterial hypertension: Role of mutations in the bone morphogenetic protein type II receptor
    • doi:10.1378/chest.08-1341. PMID:19059957
    • Davies, R.J., and Morrell, N.W. 2008. Molecular mechanisms of pulmonary arterial hypertension: role of mutations in the bone morphogenetic protein type II receptor. Chest, 134(6): 1271-1277. doi:10.1378/chest.08-1341. PMID:19059957.
    • (2008) Chest , vol.134 , Issue.6 , pp. 1271-1277
    • Davies, R.J.1    Morrell, N.W.2
  • 6
    • 59849099675 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt - b-catenin and Wnt - RhoA - Rac1 pathways
    • doi:10. 1083/jcb.200806049. PMID:19139264
    • de Jesus Perez, V.A., Alastalo, T., Wu, J.C., Axelrod, J.D., Cooke, J. P., Amieva, M., and Rabinovitch, M. 2009. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt - b-catenin and Wnt - RhoA - Rac1 pathways. J. Cell Biol. 184(1): 83-99. doi:10. 1083/jcb.200806049. PMID:19139264.
    • (2009) J. Cell Biol , vol.184 , Issue.1 , pp. 83-99
    • de Jesus, P.V.A.1    Alastalo, T.2    Wu, J.C.3    Axelrod, J.D.4    Cooke, J.P.5    Amieva, M.6    Rabinovitch, M.7
  • 7
    • 0034776773 scopus 로고    scopus 로고
    • Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
    • PMID:11602621
    • Eddahibi, S., Humbert, M., Fadel, E., Raffestin, B., Darmon, M., Capron, F., et al. 2001. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J. Clin. Invest. 108(8): 1141- 1150. PMID:11602621.
    • (2001) J. Clin. Invest , vol.108 , Issue.8 , pp. 1141-1150
    • Eddahibi, S.1    Humbert, M.2    Fadel, E.3    Raffestin, B.4    Darmon, M.5    Capron, F.6
  • 8
    • 18744413239 scopus 로고    scopus 로고
    • Pathobiology of pulmonary arterial hypertension
    • doi:10.1183/09031936.02.00081302. PMID:12503718
    • Eddahibi, S., Morrell, N., d'Ortho, M.P., Naeije, R., and Adnot, S. 2002. Pathobiology of pulmonary arterial hypertension. Eur. Respir. J. 20(6): 1559-1572. doi:10.1183/09031936.02.00081302. PMID:12503718.
    • (2002) Eur. Respir. J , vol.20 , Issue.6 , pp. 1559-1572
    • Eddahibi, S.1    Morrell, N.2    D'ortho, M.P.3    Naeije, R.4    Adnot, S.5
  • 9
    • 39449096751 scopus 로고    scopus 로고
    • Smooth muscle protein 22a-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling
    • doi:10.1161/CIRCRESAHA.107.161059. PMID: 18079409
    • El-Bizri, N., Wang, L., Merklinger, S.L., Guignabert, C., Desai, T., Urashima, T., et al. 2008. Smooth muscle protein 22a-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling. Circ. Res. 102 (3): 380-388. doi:10.1161/CIRCRESAHA.107.161059. PMID: 18079409.
    • (2008) Circ. Res , vol.102 , Issue.3 , pp. 380-388
    • El-Bizri, N.1    Wang, L.2    Merklinger, S.L.3    Guignabert, C.4    Desai, T.5    Urashima, T.6
  • 10
    • 24644441189 scopus 로고    scopus 로고
    • Genetics of pulmonary arterial hypertension: Current and future implications
    • doi:10.1055/s-2005-916150. PMID:16121312
    • Elliott, C.G. 2005. Genetics of pulmonary arterial hypertension: current and future implications. Semin. Respir. Crit. Care Med. 26(4): 365-371.doi:10.1055/s-2005-916150. PMID:16121312.
    • (2005) Semin. Respir. Crit. Care Med , vol.26 , Issue.4 , pp. 365-371
    • Elliott, C.G.1
  • 11
    • 66449098872 scopus 로고    scopus 로고
    • VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats
    • doi:10.1172/JCI36136. PMID:19381013
    • Farkas, L., Farkas, D., Ask, K., Möller, A., Gauldie, J., Margetts, P., et al. 2009. VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. J. Clin. Invest. 119(5): 1298-1311. doi:10.1172/JCI36136. PMID:19381013.
    • (2009) J. Clin. Invest. 119(5) , pp. 1298-1311
    • Farkas, L.1    Farkas, D.2    Ask, K.3    Möller, A.4    Gauldie, J.5    Margetts, P.6
  • 12
    • 0141656297 scopus 로고    scopus 로고
    • Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1
    • doi:10.1083/jcb.200212060. PMID:12963706
    • Foletta, V.C., Lim, M.A., Soosairajah, J., Kelly, A.P., Stanley, E.G., Shannon, M., et al. 2003. Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1. J. Cell Biol. 162(6): 1089-1098. doi:10.1083/jcb.200212060. PMID:12963706.
    • (2003) J. Cell Biol , vol.162 , Issue.6 , pp. 1089-1098
    • Foletta, V.C.1    Lim, M.A.2    Soosairajah, J.3    Kelly, A.P.4    Stanley, E.G.5    Shannon, M.6
  • 13
    • 33744970745 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the 5- hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
    • doi:10.1161/01.RES.0000222546.45372.a0. PMID:16614302
    • Guignabert, C., Izikki, M., Tu, L.I., Li, Z., Zadigue, P., Barlier-Mur, A.M., et al. 2006. Transgenic mice overexpressing the 5- hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ. Res. 98(10): 1323-1330. doi:10.1161/01.RES.0000222546.45372.a0. PMID:16614302.
    • (2006) Circ. Res , vol.98 , Issue.10 , pp. 1323-1330
    • Guignabert, C.1    Izikki, M.2    Tu, L.I.3    Li, Z.4    Zadigue, P.5    Barlier-Mur, A.M.6
  • 14
    • 77649337086 scopus 로고    scopus 로고
    • Role of apoptosis in pulmonary hypertension: From experimental models to clinical trials
    • doi:10.1016/j. pharmthera.2009.12.006. PMID:20117135
    • Jurasz, P., Courtman, D., Babaie, S., and Stewart, D.J. 2010. Role of apoptosis in pulmonary hypertension: from experimental models to clinical trials. Pharmacol. Ther. 126(1): 1-8. doi:10.1016/j. pharmthera.2009.12.006. PMID:20117135.
    • (2010) Pharmacol. Ther , vol.126 , Issue.1 , pp. 1-8
    • Jurasz, P.1    Courtman, D.2    Babaie, S.3    Stewart, D.J.4
  • 15
    • 61749098258 scopus 로고    scopus 로고
    • CGMP signaling in the mammalian brain: Role in synaptic plasticity and behaviour
    • doi:10.1007/978-3-540-68964- 5_24. PMID:19089345
    • Kleppisch, T., and Feil, R. 2009. cGMP signaling in the mammalian brain:role in synaptic plasticity and behaviour. Handb. Exp. Pharmacol.191(191):549-579. doi:10.1007/978-3-540-68964- 5_24. PMID:19089345.
    • (2009) Handb. Exp. Pharmacol , vol.191 , Issue.191 , pp. 549-579
    • Kleppisch, T.1    Feil, R.2
  • 16
    • 33750072892 scopus 로고    scopus 로고
    • Sertraline protects against monocrotaline-induced pulmonary hypertension in rats
    • doi:10.1111/j.1440-1681.2006.04485.x. PMID: 17042913
    • Li, X.Q., Hong, Y., Wang, Y., Zhang, X.H., and Wang, H.L. 2006. Sertraline protects against monocrotaline-induced pulmonary hypertension in rats. Clin. Exp. Pharmacol. Physiol. 33(11): 1047-1051. doi:10.1111/j.1440-1681.2006.04485.x. PMID: 17042913.
    • (2006) Clin. Exp. Pharmacol. Physiol , vol.33 , Issue.11 , pp. 1047-1051
    • Li, X.Q.1    Hong, Y.2    Wang, Y.3    Zhang, X.H.4    Wang, H.L.5
  • 17
    • 77649266429 scopus 로고    scopus 로고
    • Pathological differential diagnosis of solid-pseudopapillary neoplasm and endocrine tumors of the pancreas
    • doi:10.3748/wjg.v16.i8.1025. PMID:20180245
    • Liu, B.A., Li, Z.M., Su, Z.S., and She, X.L. 2010. Pathological differential diagnosis of solid-pseudopapillary neoplasm and endocrine tumors of the pancreas. World J. Gastroenterol. 16(8): 1025-1030. doi:10.3748/wjg.v16.i8.1025. PMID:20180245.
    • (2010) World J. Gastroenterol , vol.16 , Issue.8 , pp. 1025-1030
    • Liu, B.A.1    Li, Z.M.2    Su, Z.S.3    She, X.L.4
  • 18
    • 72549097250 scopus 로고    scopus 로고
    • Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway
    • doi:10.1186/1471-2210-9-13. PMID: 19948059
    • Lu, D., and Carson, D.A. 2009. Spiperone enhances intracellular calcium level and inhibits the Wnt signaling pathway. BMC Pharmacol. 9(1): 13-20. doi:10.1186/1471-2210-9-13. PMID: 19948059.
    • (2009) BMC Pharmacol , vol.9 , Issue.1 , pp. 13-20
    • Lu, D.1    Carson, D.A.2
  • 19
    • 34547472539 scopus 로고    scopus 로고
    • Pulmonary hypertension and the serotonin hypothesis: Where are we now
    • doi:10.1111/j.1742-1241.2007.01497.x. PMID:17663674
    • MacLean, M.R. 2007. Pulmonary hypertension and the serotonin hypothesis: where are we now? Int. J. Clin. Pract. 61(Suppl. 156): 27-31. doi:10.1111/j.1742-1241.2007.01497.x. PMID:17663674.
    • (2007) Int. J. Clin. Pract , vol.61 , Issue.SUPPL. 156 , pp. 27-31
    • Maclean, M.R.1
  • 20
    • 77951227152 scopus 로고    scopus 로고
    • The serotonin hypothesis of pulmonary hypertension revisited
    • doi:10.1007/978-1-60761-500-2_20. PMID:20204739
    • Maclean, M.R., and Dempsie, Y. 2010. The serotonin hypothesis of pulmonary hypertension revisited. Adv. Exp. Med. Biol. 661: 309- 322. doi:10.1007/978-1-60761-500-2_20. PMID:20204739.
    • (2010) Adv. Exp. Med. Biol. 661: 309- , pp. 322
    • Maclean, M.R.1    Dempsie, Y.2
  • 21
    • 0028172409 scopus 로고
    • Adenosine 3 receptors regulate serotonin transport via nitric oxide and cGMP
    • PMID:7525554
    • Miller, K.J., and Hoffman, B.J. 1994. Adenosine 3 receptors regulate serotonin transport via nitric oxide and cGMP. J. Biol. Chem. 269(44): 27351-27356. PMID:7525554.
    • (1994) J. Biol. Chem , vol.269 , Issue.44 , pp. 27351-27356
    • Miller, K.J.1    Hoffman, B.J.2
  • 22
    • 77952725384 scopus 로고    scopus 로고
    • Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve
    • doi:10.1016/j.aanat.2010.02. 006. PMID:20427168
    • Mohamed, S.A., Misfeld, M., Hanke, T., Charitos, E.I., Bullerdiek, J., Belge, G., et al. 2010. Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve. Ann. Anat. 192(3): 145-150. doi:10.1016/j.aanat.2010.02. 006. PMID:20427168.
    • (2010) Ann. Anat , vol.192 , Issue.3 , pp. 145-150
    • Mohamed, S.A.1    Misfeld, M.2    Hanke, T.3    Charitos, E.I.4    Bullerdiek, J.5    Belge, G.6
  • 23
    • 67649599147 scopus 로고    scopus 로고
    • Cellular and molecular basis of pulmonary arterial hypertension
    • doi:10.1016/j.jacc.2009.04.018. PMID:19555855
    • Morrell, N.W., Adnot, S., Archer, S.L., Dupuis, J., Jones, P.L., MacLean, M.R., et al. 2009. Cellular and molecular basis of pulmonary arterial hypertension. J. Am. Coll. Cardiol. 54(1 Suppl): S20-S31. doi:10.1016/j.jacc.2009.04.018. PMID:19555855.
    • (2009) J. Am. Coll. Cardiol , vol.54 , Issue.1 , pp. 20-31
    • Morrell, N.W.1    Adnot, S.2    Archer, S.L.3    Dupuis, J.4    Jones, P.L.5    Maclean, M.R.6
  • 24
    • 34247387518 scopus 로고    scopus 로고
    • Dysregulated bone morphogenetic protein signaling in monocrotalineinduced pulmonary arterial hypertension
    • doi:10.1161/ATVBAHA.107.141200. PMID:17347486
    • Morty, R.E., Nejman, B., Kwapiszewska, G., Hecker, M., Zakrzewicz, A., Kouri, F.M., et al. 2007. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Arterioscler. Thromb. Vasc. Biol. 27(5): 1072-1078. doi:10.1161/ATVBAHA.107.141200. PMID:17347486.
    • (2007) Arterioscler. Thromb.Vasc Biol , vol.27 , Issue.5 , pp. 1072-1078
    • Morty, R.E.1    Nejman, B.2    Kwapiszewska, G.3    Hecker, M.4    Zakrzewicz, A.5    Kouri, F.M.6
  • 25
    • 0242330206 scopus 로고    scopus 로고
    • Physiology and pathophysiology of vascular signaling controlled by guanosine 3′,5′-cyclic monophosphatedependent protein kinase
    • doi:10.1161/01.CIR.0000094403.78467.C3. PMID:14597579
    • Münzel, T., Feil, R., Mülsch, A., Lohmann, S.M., Hofmann, F., and Walter, U. 2003. Physiology and pathophysiology of vascular signaling controlled by guanosine 3′,5′-cyclic monophosphatedependent protein kinase. Circulation, 108(18): 2172-2183. doi:10.1161/01.CIR.0000094403.78467.C3. PMID:14597579.
    • (2003) Circulation, 108(18) , vol.108 , Issue.18 , pp. 2172-2183
    • Münzel, T.1    Feil, R.2    Mülsch, A.3    Lohmann, S.M.4    Hofmann, F.5    Walter, U.6
  • 26
    • 40049100690 scopus 로고    scopus 로고
    • Narrative review: The enigma of pulmonary arterial hypertension: New insights from genetic studies
    • PMID:18283205
    • Newman, J.H., Phillips, J.A., III, and Loyd, J.E. 2008. Narrative review: the enigma of pulmonary arterial hypertension: new insights from genetic studies. Ann. Intern. Med. 148(4): 278-283. PMID:18283205.
    • (2008) Ann. Intern. Med , vol.148 , Issue.4 , pp. 278-283
    • Newman, J.H.1    Phillips, J.A.2    Loyd, J.E.3
  • 27
    • 58149467106 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension and BMP system abnormality
    • PMID:19051724
    • Otsuka, F. 2008. Pulmonary arterial hypertension and BMP system abnormality. Nippon Rinsho, 66(11): 2083-2090. PMID:19051724.
    • (2008) Nippon Rinsho , vol.66 , Issue.11 , pp. 2083-2090
    • Otsuka, F.1
  • 28
    • 0034778907 scopus 로고    scopus 로고
    • Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension
    • PMID:11602617
    • Rabinovitch, M. 2001. Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension. J. Clin. Invest. 108(8): 1109-1111. PMID:11602617.
    • (2001) J. Clin. Invest , vol.108 , Issue.8 , pp. 1109-1111
    • Rabinovitch, M.1
  • 29
    • 30144434322 scopus 로고    scopus 로고
    • Cellular and molecular pathobiology of pulmonary hypertension conference summary
    • doi:10.1378/chest.128.6_suppl.642S. PMID:16373886
    • Rabinovitch, M. 2005. Cellular and molecular pathobiology of pulmonary hypertension conference summary. Chest, 128(6 Suppl.): 642-646. doi:10.1378/chest.128.6_suppl.642S. PMID:16373886.
    • (2005) Chest , vol.128 , Issue.6 , pp. 642-646
    • Rabinovitch, M.1
  • 30
    • 34147136670 scopus 로고    scopus 로고
    • Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells
    • doi:10.1016/j. vph.2007.01.005. PMID:17336165
    • Ramos, M., Lamé, M.W., Segall, H.J., and Wilson, D.W. 2007. Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells. Vascul. Pharmacol. 46(6): 439-448. doi:10.1016/j. vph.2007.01.005. PMID:17336165.
    • (2007) Vascul. Pharmacol , vol.46 , Issue.6 , pp. 439-448
    • Ramos, M.1    Lamé, M.W.2    Segall, H.J.3    Wilson, D.W.4
  • 31
    • 40949140591 scopus 로고    scopus 로고
    • Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery
    • doi:10.1186/1465-9921-9-19. PMID:18269754
    • Sage, E., Mercier, O., Van den Eyden, F., de Perrot, M., Barlier-Mur, A.M., Dartevelle, P., et al. 2008. Endothelial cell apoptosis in chronically obstructed and reperfused pulmonary artery. Respir. Res. 9(1): 19-28. doi:10.1186/1465-9921-9-19. PMID:18269754.
    • (2008) Respir. Res , vol.9 , Issue.1 , pp. 19-28
    • Sage, E.1    Mercier, O.2    Van den, E.F.3    de Perrot, M.4    Barlier-Mur, A.M.5    Dartevelle, P.6
  • 32
    • 67349167022 scopus 로고    scopus 로고
    • Novel crosstalk to BMP signaling: CGMPdependent kinase I modulates BMP receptor and Smad activity
    • doi:10.1038/emboj.2009.103. PMID:19424179
    • Schwappacher, R., Weiske, J., Heining, E., Ezerski, V., Marom, B., Henis, Y.I., et al. 2009. Novel crosstalk to BMP signaling: cGMPdependent kinase I modulates BMP receptor and Smad activity. EMBO J. 28(11): 1537-1550. doi:10.1038/emboj.2009.103. PMID:19424179.
    • (2009) EMBO J , vol.28 , Issue.11 , pp. 1537-1550
    • Schwappacher, R.1    Weiske, J.2    Heining, E.3    Ezerski, V.4    Marom, B.5    Henis, Y.I.6
  • 33
    • 38049055683 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein signaling in human pulmonary vascular development
    • doi:10.1002/path.2261. PMID:17992660
    • Southwood, M., Jeffery, T.K., Yang, X., Upton, P.D., Hall, S.M., Atkinson, C., et al. 2008. Regulation of bone morphogenetic protein signaling in human pulmonary vascular development. J. Pathol. 214(1): 85-95. doi:10.1002/path.2261. PMID:17992660.
    • (2008) J. Pathol , vol.214 , Issue.1 , pp. 85-95
    • Southwood, M.1    Jeffery, T.K.2    Yang, X.3    Upton, P.D.4    Hall, S.M.5    Atkinson, C.6
  • 34
    • 69849099060 scopus 로고    scopus 로고
    • CGMP-dependent protein kinase Ia associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake
    • doi:10.1186/1756-6606-2-26. PMID:19656393
    • Steiner, J.A., Carneiro, A.M., Wright, J., Matthies, H.J., Prasad, H.C., Nicki, C.K., et al. 2009. cGMP-dependent protein kinase Ia associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake. Mol. Brain, 2(1): 26-37. doi:10.1186/1756-6606-2-26. PMID:19656393.
    • (2009) Mol. Brain , vol.2 , Issue.1 , pp. 26-37
    • Steiner, J.A.1    Carneiro, A.M.2    Wright, J.3    Matthies, H.J.4    Prasad, H.C.5    Nicki, C.K.6
  • 35
    • 69549130512 scopus 로고    scopus 로고
    • Propylthiouracil attenuates monocrotaline-induced pulmonary arterial hypertension in rats
    • doi:10.1253/circj.CJ-09-0074. PMID:19602776
    • Sun, C.K., Yuen, C.M., Kao, Y.H., Chang, L.T., Chua, S., Sheu, J.J., et al. 2009. Propylthiouracil attenuates monocrotaline-induced pulmonary arterial hypertension in rats. Circ. J. 73(9): 1722-1730. doi:10.1253/circj.CJ-09-0074. PMID:19602776.
    • (2009) Circ. J , vol.73 , Issue.9 , pp. 1722-1730
    • Sun, C.K.1    Yuen, C.M.2    Kao, Y.H.3    Chang, L.T.4    Chua, S.5    Sheu, J.J.6
  • 36
    • 33644958041 scopus 로고    scopus 로고
    • Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension
    • doi:10.1152/ajplung.00206.2005. PMID:16361357
    • Takahashi, H., Goto, N., Kojima, Y., Tsuda, Y., Morio, Y., Muramatsu, M., and Fukuchi, Y. 2006. Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension. Am. J. Physiol. Lung Cell. Mol. Physiol. 290(3): 450-458 doi:10.1152/ajplung.00206.2005. PMID:16361357.
    • (2006) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.290 , Issue.3 , pp. 450-458
    • Takahashi, H.1    Goto, N.2    Kojima, Y.3    Tsuda, Y.4    Morio, Y.5    Muramatsu, M.6    Fukuchi, Y.7
  • 37
    • 0034904703 scopus 로고    scopus 로고
    • Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene
    • doi:10.1183/09031936.01.00202701. PMID:11491145
    • Tuder, R.M., Yeager, M.E., Geraci, M., Golpon, H.A., and Voelkel, N.F. 2001. Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene. Eur. Respir. J. 17(6): 1065-1069. doi:10.1183/09031936.01.00202701. PMID:11491145.
    • (2001) Eur. Respir. J , vol.17 , Issue.6 , pp. 1065-1069
    • Tuder, R.M.1    Yeager, M.E.2    Geraci, M.3    Golpon, H.A.4    Voelkel, N.F.5
  • 38
    • 65749097812 scopus 로고    scopus 로고
    • TGF-b and BMPR-II pharmacology implications for pulmonary vascular diseases
    • doi:10.1016/j.coph.2009. 02.007. PMID:19321386
    • Upton, P.D., and Morrell, N.W. 2009. TGF-b and BMPR-II pharmacology implications for pulmonary vascular diseases. Curr. Opin. Pharmacol. 9(3): 274-280 doi:10.1016/j.coph.2009. 02.007. PMID:19321386.
    • (2009) Curr. Opin. Pharmacol , vol.9 , Issue.3 , pp. 274-280
    • Upton, P.D.1    Morrell, N.W.2
  • 39
    • 67650188576 scopus 로고    scopus 로고
    • BMP and activin type-II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells
    • doi:10.1074/jbc.M109.002881. PMID:19366699
    • Upton, P.D., Davies, R.J., Trembath, R.C., and Morrell, N.W. 2009. BMP and activin type-II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells. J. Biol. Chem. 284(23): 15794-15804. doi:10.1074/jbc.M109.002881. PMID:19366699.
    • (2009) J. Biol. Chem , vol.284 , Issue.23 , pp. 15794-15804
    • Upton, P.D.1    Davies, R.J.2    Trembath, R.C.3    Morrell, N.W.4
  • 40
    • 0035100955 scopus 로고    scopus 로고
    • 5-HT1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery in monocrotaline-induced pulmonary hypertensive rats
    • PMID:11742576
    • Wang, H.L., Dong, X., Zhang, X.H., and Xing, J. 2001. 5-HT1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery in monocrotaline-induced pulmonary hypertensive rats. Acta Pharmacol. Sin. 22(3): 269-273. PMID:11742576.
    • (2001) Acta Pharmacol. Sin , vol.22 , Issue.3 , pp. 269-273
    • Wang, H.L.1    Dong, X.2    Zhang, X.H.3    Xing, J.4
  • 41
    • 42949178711 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells
    • doi:10.1074/jbc.M706797200. PMID:18042551
    • Yu, P.B., Deng, D.Y., Beppu, H., Hong, C.C., Lai, C., Hoyng, S.A., et al. 2008. Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells. J. Biol. Chem. 283(7): 3877-3888. doi:10.1074/jbc.M706797200. PMID:18042551.
    • (2008) J. Biol. Chem , vol.283 , Issue.7 , pp. 3877-3888
    • Yu, P.B.1    Deng, D.Y.2    Beppu, H.3    Hong, C.C.4    Lai, C.5    Hoyng, S.A.6
  • 42
    • 42649136572 scopus 로고    scopus 로고
    • Role of the TGF-b/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension
    • doi:10.1164/rccm.200707-1083OC. PMID:18202349
    • Zaiman, A.L., Podowski, M., Medicherla, S., Gordy, K., Xu, F., Zhen, L., et al. 2008. Role of the TGF-b/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. Am. J. Respir. Crit. Care Med. 177(8): 896-905. doi:10.1164/rccm.200707-1083OC. PMID:18202349.
    • (2008) Am. J. Respir. Crit. Care Med , vol.177 , Issue.8 , pp. 896-905
    • Zaiman, A.L.1    Podowski, M.2    Medicherla, S.3    Gordy, K.4    Xu, F.5    Zhen, L.6
  • 43
    • 34250370351 scopus 로고    scopus 로고
    • Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension
    • doi:10.1161/CIRCULATIONAHA.106.670026. PMID:17515463
    • Zakrzewicz, A., Hecker, M., Marsh, L.M., Kwapiszewska, G., Nejman, B., Long, L., et al. 2007. Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension. Circulation, 115(23): 2957- 2968 doi:10.1161/CIRCULATIONAHA.106.670026. PMID:17515463.
    • (2007) Circulation , vol.115 , Issue.23 , pp. 2957-2968
    • Zakrzewicz, A.1    Hecker, M.2    Marsh, L.M.3    Kwapiszewska, G.4    Nejman, B.5    Long, L.6
  • 44
    • 68549112957 scopus 로고    scopus 로고
    • Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: Potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats
    • doi:10.1111/j.1440-1681.2009.05168.x. PMID:19298536
    • Zhai, F.G., Zhang, X.H., and Wang, H.L. 2009. Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats. Clin. Exp. Pharmacol. Physiol. 36(8): 850-856. doi:10.1111/j.1440-1681.2009.05168.x. PMID:19298536.
    • (2009) Clin. Exp. Pharmacol. Physiol , vol.36 , Issue.8 , pp. 850-856
    • Zhai, F.G.1    Zhang, X.H.2    Wang, H.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.