Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma

Journal of Trauma - Injury, Infection and Critical Care

Volumn 70, Issue 6, 2011, Pages 1389-1397

  Hofstra, Jorrit J ^a   Vlaar, Alexander P ^a   Knape, Paul ^b   Mackie, Dave P ^b   Determann, Rogier M ^a   Choi, Goda ^a   Van Der Poll, Tom ^a   Levi, Marcel ^a   Schultz, Marcus J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RED CROSS HOSPITAL   (Netherlands)

Author keywords

Burn injuries; Coagulation; Fibrinolysis; Inhalation trauma

Indexed keywords

ACTIVATED PROTEIN C; ANTITHROMBIN; FIBRIN DEGRADATION PRODUCT; THROMBIN;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; BLOOD CLOTTING DISORDER; BURN; CASE REPORT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FIBRINOLYSIS; HUMAN; LUNG BURN; LUNG FLUID; LUNG INJURY; LUNG LAVAGE; MALE; PRIORITY JOURNAL;

ADULT; AGED; APACHE; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION FACTORS; BRONCHOALVEOLAR LAVAGE; BURNS, INHALATION; CASE-CONTROL STUDIES; FEMALE; FIBRINOLYSIS; HUMANS; INJURY SEVERITY SCORE; LINEAR MODELS; MALE; MIDDLE AGED; NETHERLANDS; PNEUMONIA; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RISK FACTORS; STATISTICS, NONPARAMETRIC;

EID: 79958831595     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e31820f85a7     Document Type: Article

References (25)

1. Dancey DR, Hayes J, Gomez M, et al. ARDS in patients with thermal injury. Intensive Care Med. 1999;25:1231-1236.
2. Barillo DJ, Goode R. Fire fatality study: demographics of fire victims. Burns. 1996;22:85-88. (Pubitemid 26050859)
3. Santaniello JM, Luchette FA, Esposito TJ, et al. Ten year experience of burn, trauma, and combined burn/trauma injuries comparing outcomes. J Trauma. 2004;57:696-700.
4. Günther A, Mosavi P, Heinemann S, et al. Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia. Comparison with the acute respiratory distress syndrome. Am J Respir Crit Care Med. 2000;161:454-462. (Pubitemid 30129452)
5. Hofstra JJ, Haitsma JJ, Juffermans NP, Levi M, Schultz MJ. The role of bronchoalveolar hemostasis in the pathogenesis of acute lung injury. Semin Thromb Hemost. 2008;34:475-484.
6. Murray JF, Matthay MA, Luce JM, Flick MR. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis. 1988;138: 720-723.
7. Millo JL, Schultz MJ, Williams C, et al. Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia. Intensive Care Med. 2004;30:68-74. (Pubitemid 38147109)
8. Schultz MJ, Millo J, Levi M, et al. Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia. Thorax. 2004;59:130-135. (Pubitemid 38223484)
9. Ware LB, Matthay MA, Parsons PE, et al. Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/ acute respiratory distress syndrome. Crit Care Med. 2007;35:1821-1828. (Pubitemid 47220354)
10. Johnson K, Choi Y, DeGroot E, Samuels I, Creasey A, Aarden L. Potential mechanisms for a proinflammatory vascular cytokine response to coagulation activation. J Immunol. 1998;160:5130-5135. (Pubitemid 28215352)
11. Seeger W, Elssner A, Günther A, Krämer HJ, Kalinowski HO. Lung surfactant phospholipids associate with polymerizing fibrin: loss of surface activity. Am J Respir Cell Mol Biol. 1993;9:213-220.
12. Herndon DN, Traber DL, Niehaus GD, Linares HA, Traber LD. The pathophysiology of smoke inhalation injury in a sheep model. J Trauma. 1984;24:1044-1051. (Pubitemid 15194164)
13. Basadre JO, Sugi K, Traber DL, Traber LD, Niehaus GD, Herndon DN. The effect of leukocyte depletion on smoke inhalation injury in sheep. Surgery. 1988;104:208-215.
14. Cox RA, Burke AS, Oliveras G, et al. Acute bronchial obstruction in sheep: histopathology and gland cytokine expression. Exp Lung Res. 2005;31:819-837. (Pubitemid 43732309)
15. Cox RA, Burke AS, Soejima K, et al. Airway obstruction in sheep with burn and smoke inhalation injuries. Am J Respir Cell Mol Biol. 2003; 29:295-302. (Pubitemid 37093987)
16. Enkhbaatar P, Murakami K, Cox R, et al. Aerosolized tissue plasminogen inhibitor improves pulmonary function in sheep with burn and smoke inhalation. Shock. 2004;22:70-75. (Pubitemid 40228213)
17. Costello JM, Steinhorn D, McColley S, Gerber ME, Kumar SP. Treatment of plastic bronchitis in a Fontan patient with tissue plasminogen activator: a case report and review of the literature. Pediatrics. 2002;109:e67.
18. Cox CS Jr, Zwischenberger JB, Traber DL, Traber LD, Haque AK, Herndon DN. Heparin improves oxygenation and minimizes barotrauma after severe smoke inhalation in an ovine model. Surg Gynecol Obstet. 1993;176:339-349. (Pubitemid 23097953)
19. Murakami K, McGuire R, Cox RA, et al. Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep. Shock. 2002;18:236-241.
20. Maybauer MO, Maybauer DM, Fraser JF, et al. Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis. Crit Care Med. 2006;34:2432-2438. (Pubitemid 44262031)
21. Enkhbaatar P, Esechie A, Wang J, et al. Combined anticoagulants ameliorate acute lung injury in sheep after burn and smoke inhalation. Clin Sci (Lond). 2008;114:321-329. (Pubitemid 351294008)
22. Enkhbaatar P, Cox RA, Traber LD, et al. Aerosolized anticoagulants ameliorate acute lung injury in sheep after exposure to burn and smoke inhalation. Crit Care Med. 2007;35:2805-2810. (Pubitemid 350175779)
23. Desai MH, Mlcak R, Richardson J, Nichols R, Herndon DN. Reduction in mortality in pediatric patients with inhalation injury with aerosolized heparin/N-acetylcystine [correction of acetylcystine] therapy. J Burn Care Rehabil. 1998;19:210-212. (Pubitemid 28237673)
24. Lavrentieva A, Kontakiotis T, Bitzani M, et al. Early coagulation disorders after severe burn injury: impact on mortality. Intensive Care Med. 2008;34:700-706. (Pubitemid 351660090)
25. Liffner G, Bak Z, Reske A, Sjöberg F. Inhalation injury assessed by score does not contribute to the development of acute respiratory distress syndrome in burn victims. Burns. 2005;31:263-268. (Pubitemid 40363931)