Garcinia gardneriana (Planchon & Triana) Zappi. (Clusiaceae) as a topical anti-inflammatory alternative for cutaneous inflammation

Basic and Clinical Pharmacology and Toxicology

Volumn 109, Issue 1, 2011, Pages 56-62

  Otuki, Michel F ^a   Bernardi, Camila A ^b   Prudente, Arthur S ^b   Laskoski, Kerly ^b   Gomig, Franciane ^b   Horinouchi, Cintia D S ^b   Guimarães, Claudio L ^c   Ferreira, Juliano ^d   Delle Monache, Franco ^e   Cechinel Filho, Valdir ^e   Cabrini, Daniela A ^b  

^a STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

^b FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^c Department of Pharmaceutical Sciences   (Brazil)

^d FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^e Nucleus of Chemical Pharmaceutical Researches   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

13 NARINGENIN II 8 ERIODICTYOL; ANTIINFLAMMATORY AGENT; CROTON OIL; DEXAMETHASONE; ERIODICTYOL; GARCINIA GARDNERIANA EXTRACT; MORELLOFLAVONE; MYELOPEROXIDASE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BARK; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG ISOLATION; DRUG STRUCTURE; EAR EDEMA; EDEMA; ENZYME ACTIVITY; GARCINIA; GARCINIA GARDNERIANA; HISTOPATHOLOGY; LEUKOCYTE MIGRATION; MALE; MOUSE; NONHUMAN; PLANT LEAF; PLANT SEED; PRIORITY JOURNAL; SKIN INFLAMMATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL MOVEMENT; DISEASE MODELS, ANIMAL; GARCINIA; INFLAMMATION; INHIBITORY CONCENTRATION 50; LEUKOCYTES; MALE; MICE; PEROXIDASE; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SKIN DISEASES; TIME FACTORS;

CLUSIACEAE; GARCINIA GARDNERIANA;

EID: 79958825365     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2011.00689.x     Document Type: Article

References (31)

1. Portugal M, Barak V, Ginsburg I, Kohen R. Interplay among oxidants, antioxidants, and cytokines in skin disorders: present status and future considerations. Biomed Pharmacother 2007;61:412-22.
2. Gilroy DW, Lawrence T, Perretti M, Rossi AG. Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov 2004;3:401-16.
3. Becker PFL (ed.). Inflammation. Geral Pathology. Sarvier, São Paulo, Brazil, 1997;140-93.
4. Nickoloff BJ, Nestle FO. Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest 2004;113:1664-75.
5. Song HY, Lee JA, Ju SM, Yoo KY, Won MH, Kwon HJ et al. Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. Biochem Pharmacol 2008;75:1348-57.
6. Basso LA, da Silva LH, Fett-Neto AG, de Azevedo WF Jr, Moreira Ide S, Palma MS et al. The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases--a review. Mem Inst Oswaldo Cruz 2005;100:475-506.
7. Calixto JB. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res 2000;33:179-89.
8. Guimarães CL, Otuki MF, Beirith A, Cabrini DA. A review on the therapeutic potential of Garcinia gardneriana. Dynamis 2004;12:6-12.
9. Corrêa MP. Dicionário das plantas úteis do Brasil e das exóticas cultivadas. Ministerio da Agricultura, IBDF, Rio de Janeiro, 1984.
10. Cechinel Filho V. Advances and perspectives in the field of active natural products: studies conducted at NIQFAR/UNIVALI. Quim Nova 2000;23:680-4.
11. Cechinel Filho V, da Silva KL, de Souza MM, Oliveira AE, Yunes RA, Guimaraes CL et al. I3-naringenin-II8 - 4'OMe-eriodictyol: a new potential analgesic agent isolated from Rheedia gardneriana leaves. Z Naturforsch C 2000;55:820-3.
12. Luzzi R, Guimarães CL, Verdi LG, Simionatto EL, Delle Monache F, Yunes RA et al. Isolation of biflavonoids with analgesic activity from Rheedia gardneriana leaves. Phytomedicine 1997;4:139-42.
13. Castardo JC, Prudente AS, Ferreira J, Guimaraes CL, Monache FD, Filho VC et al. Anti-inflammatory effects of hydroalcoholic extract and two biflavonoids from Garcinia gardneriana leaves in mouse paw oedema. J Ethnopharmacol 2008;118:405-11.
14. Otuki MF, Vieira-Lima F, Malheiros A, Yunes RA, Calixto JB. Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene. Eur J Pharmacol 2005;507:253-9.
15. Swingle KF, Reiter MJ, Schwartzmiller DH. Comparison of croton oil and cantharidin induced inflammations of the mouse ear and their modification by topically applied drugs. Arch Int Pharmacodyn Ther 1981;254:168-76.
16. Tragni E, Tubaro A, Melis S, Galli CL. Evidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacina B. Food Chem Toxicol 1985;23:317-9.
17. Suzuki K, Ota H, Sasagawa S, Sakatani T, Fujikura T. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Anal Biochem 1983;132:345-52.
18. De Young LM, Kheifets JB, Ballaron SJ, Young JM. Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents. Agents Actions 1989;26:335-41.
19. Recio MC, Giner RM, Uriburu L, Manez S, Cerda M, De la Fuente JR et al. In vivo activity of pseudoguaianolide sesquiterpene lactones in acute and chronic inflammation. Life Sci 2000;66:2509-18.
20. Keston AS, Brandt R. The fluorometric analysis of ultramicro quantities of hydrogen peroxide. Anal Biochem 1965;11:1-5.
21. Driver AS, Kodavanti PR, Mundy WR. Age-related changes in reactive oxygen species production in rat brain homogenates. Neurotoxicol Teratol 2000;22:175-81.
22. Gábor M. Ear inflammation Models and Their Pharmacological Applications. Akadémiai Kiadó, Budapest, 2000.
23. Gabor M. Models of acute inflammation in the ear. Methods Mol Biol 2003;225:129-37.
24. Murakawa M, Yamaoka K, Tanaka Y, Fukuda Y. Involvement of tumor necrosis factor (TNF)-alpha in phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin edema in mice. Biochem Pharmacol 2006;71:1331-6.
25. Sherwood ER, Toliver-Kinsky T. Mechanisms of the inflammatory response. Best Pract Res Clin Anaesthesiol 2004;18:385-405.
26. Gil B, Sanz MJ, Terencio MC, Gunasegaran R, Paya M, Alcaraz MJ. Morelloflavone, a novel biflavonoid inhibitor of human secretory phospholipase A2 with anti-inflammatory activity. Biochem Pharmacol 1997;53:733-40.
27. Pang X, Yi T, Yi Z, Cho SG, Qu W, Pinkaew D et al. Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways. Cancer Res 2009;69:518-25.
28. Pinkaew D, Cho SG, Hui DY, Wiktorowicz JE, Hutadilok-Towatana N, Mahabusarakam W et al. Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration. Biochim Biophys Acta 2009; 1790:31-9.
29. Sadik CD, Sies H, Schewe T. Inhibition of 15-lipoxygenases by flavonoids: structure-activity relations and mode of action. Biochem Pharmacol 2003;65:773-81.
30. Nakamura Y, Kozuka M, Naniwa K, Takabayashi S, Torikai K, Hayashi R et al. Arachidonic acid cascade inhibitors modulate phorbol ester-induced oxidative stress in female ICR mouse skin: differential roles of 5-lipoxygenase and cyclooxygenase-2 in leukocyte infiltration and activation. Free Radic Biol Med 2003; 35:997-1007.
31. Petersen TK. In vivo pharmacological disease models for psoriasis and atopic dermatitis in drug discovery. Basic Clin Pharmacol Toxicol 2006;99:104-15.