Humanized Rag1-/-γc-/- mice support multilineage hematopoiesis and are susceptible to HIV-1 infection via systemic and vaginal routes

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Akkina, Ramesh ^a   Berges, Bradford K ^a,c   Palmer, Brent E ^b   Remling, Leila ^a   Neff, C Preston ^a   Kuruvilla, Jes ^a   Connick, Elizabeth ^b   Folkvord, Joy ^b   Gagliardi, Kathy ^a   Kassu, Afework ^b   Akkina, Sarah R ^a,d  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c BRIGHAM YOUNG UNIVERSITY   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; GAMMA CYSTEINE; RAG1 PROTEIN; UNCLASSIFIED DRUG; CD34 ANTIGEN; CD45 ANTIGEN; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; IMMUNOGLOBULIN; INTERLEUKIN 2 RECEPTOR GAMMA; RAG 1 PROTEIN; RAG-1 PROTEIN; RAG2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD34 SELECTION; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; HELPER CELL; HEMATOPOIESIS; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VIVO STUDY; INFECTION SENSITIVITY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; VIRUS TRANSMISSION; VIRUS VIRULENCE; ANIMAL; ANTIBODY PRODUCTION; CELL LINEAGE; CYTOLOGY; DISEASE PREDISPOSITION; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LYMPHOID TISSUE; METABOLISM; MUCOSA; PATHOGENICITY; PERITONEUM; VAGINA; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1; MUS;

ANIMALS; ANTIBODY FORMATION; ANTIGENS, CD34; ANTIGENS, CD45; CD4-POSITIVE T-LYMPHOCYTES; CELL LINEAGE; DISEASE SUSCEPTIBILITY; DNA-BINDING PROTEINS; FEMALE; FLOW CYTOMETRY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HIV INFECTIONS; HIV-1; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; LYMPHOID TISSUE; MICE; MUCOUS MEMBRANE; PERITONEUM; VAGINA;

EID: 79958812814     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020169     Document Type: Article

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