Elevated plasma myeloperoxidase levels in relation to circulating inflammatory markers in coronary artery disease

Biomarkers in Medicine

Volumn 5, Issue 3, 2011, Pages 377-385

  Samsamshariat, Saed Ziaaldin ^a   Basati, Gholam ^a   Movahedian, Ahmad ^a   Pourfarzam, Morteza ^a   Sarrafzadegan, Nizal ^b  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

myeloperoxidase; stable CAD; unstable CAD

Indexed keywords

C REACTIVE PROTEIN; LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE; NITRATE; NITRITE;

ADULT; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; ENZYME IMMUNOASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PROTEIN BLOOD LEVEL; PROTEIN METABOLISM;

ADULT; AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CORONARY ARTERY DISEASE; FEMALE; HUMANS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; NITRATES; NITRITES; OXIDATION-REDUCTION; PEROXIDASE; RISK FACTORS;

EID: 79958798597     PISSN: 17520363     EISSN: 17520371     Source Type: Journal    
DOI: 10.2217/bmm.11.28     Document Type: Article

References (37)

1. Libby P, Ridker PM, Maseri A: Inflammation and atherosclerosis. Circulation 105(9), 1135-1143 (2002). (Pubitemid 34212626)
2. Fichtlscherer S, Heeschen C, Zeiher AM: Inflammatory markers and coronary artery disease. Curr. Opin. Pharmacol. 4(2), 124-131 (2004). (Pubitemid 38444046)
3. Lau D, Baldus S: Myeloperoxidase and its contributory role in inflammatory vascular disease. Pharmacol. Ther. 111(1), 16-26 (2006). (Pubitemid 43765542)
4. Ikitimur B, Karadag B: Role of myeloperoxidase in cardiology. Future Cardiol. 6(5), 693-702 (2010).
5. Stocker R, Keaney JF Jr: Role of oxidative modifications in atherosclerosis. Physiol. Rev. 84(4), 1381-1478 (2004). (Pubitemid 39302636)
6. Carr AC, McCall MR, Frei B: Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection. Arterioscler. Thromb. Vasc. Biol. 20(7), 1716-1723 (2000). (Pubitemid 30470585)
7. Abu-Soud HM, Hazen SL: Nitric oxide is a physiological substrate for mammalian peroxidases. J. Biol. Chem. 275(48), 37524-37532 (2000). (Pubitemid 32004861)
8. Xu J, Xie Z, Reece R, Pimental D, Zou MH: Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite. Arterioscler. Thromb. Vasc. Biol. 26(12), 2688-2695 (2006).
9. Nicholls SJ, Hazen SL: The role of myeloperoxidase in the pathogenesis of coronary artery disease. Jpn J. Infect. Dis. 57(5), S21-S22 (2004). (Pubitemid 39545719)
10. Buffon A, Biasucci LM, Liuzzo G, D'Onofrio G, Crea F, Maseri A: Widespread coronary inflammation in unstable angina. N. Engl. J. Med. 347(1), 5-12 (2002). (Pubitemid 34728951)
11. Zhang R, Brennan ML, Fu X et al.: Association between myeloperoxidase levels and risk of coronary artery disease. JAMA 286(17), 2136-2142 (2001). (Pubitemid 34041599)
12. Duzguncinar O, Yavuz B, Hazirolan T et al.: Plasma myeloperoxidase is related to the severity of coronary artery disease. Acta Cardiol. 63(2), 147-152 (2008). (Pubitemid 351548698)
13. Moldoveanu E, Tanaseanu C, Tanaseanu S et al.: Plasma markers of endothelial dysfunction in Type 2 diabetics. Eur. J. Intern. Med. 17(1), 38-42 (2006). (Pubitemid 43003460)
14. Eleuteri E, Di SA, Ricciardolo FL et al.: Increased nitrotyrosine plasma levels in relation to systemic markers of inflammation and myeloperoxidase in chronic heart failure. Int. J. Cardiol. 135(3), 386-390 (2009).
15. Yunoki K, Naruko T, Komatsu R et al.: Relation of elevated levels of plasma myeloperoxidase to impaired myocardial microcirculation after reperfusion in patients with acute myocardial infarction. Am. J. Cardiol. 105(7), 922-929 (2010).
16. Kubala L, Lu G, Baldus S, Berglund L, Eiserich JP: Plasma levels of myeloperoxidase are not elevated in patients with stable coronary artery disease. Clin. Chim. Acta 394(1-2), 59-62 (2008).
17. Ndrepepa G, Braun S, Mehilli J, von BN, Schomig A, Kastrati A: Myeloperoxidase level in patients with stable coronary artery disease and acute coronary syndromes. Eur. J. Clin. Invest. 38(2), 90-96 (2008). (Pubitemid 351143413)
18. Miller M, Mead LA, Kwiterovich PO Jr, Pearson TA: Dyslipidemias with desirable plasma total cholesterol levels and angiographically demonstrated coronary artery disease. Am. J. Cardiol. 65(1), 1-5 (1990). (Pubitemid 20013915)
19. Apple FS, Wu AH, Mair J et al.: Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. Clin. Chem. 51(5), 810-824 (2005). (Pubitemid 40577917)
20. Zouaoui Boudjeltia K, Moguilevsky N, Legssyer I et al.: Oxidation of low density lipoproteins by myeloperoxidase at the surface of endothelial cells: an additional mechanism to subendothelium oxidation. Biochem. Biophys. Res. Commun. 325(2), 434-438 (2004). (Pubitemid 39458014)
21. Higashi Y, Noma K, Yoshizumi M, Kihara Y: Endothelial function and oxidative stress in cardiovascular diseases. Circ. J. 73(3), 411-418 (2009).
22. Baldus S, Heeschen C, Meinertz T et al.: Myeloperoxidase serum levels predict risk in patients with acute coronary syndrome. Circulation 108(12), 1440-1445 (2003). (Pubitemid 37176448)
23. Brennan ML, Penn MS, Van LF et al.: Prognostic value of myeloperoxidase in patients with chest pain. N. Engl. J. Med. 349(17), 1595-1604 (2003). (Pubitemid 37288567)
24. Cavusoglu E, Ruwende C, Eng C et al.: Usefulness of baseline plasma myeloperoxidase levels as an independent predictor of myocardial infarction at two years in patients presenting with acute coronary syndrome. Am. J. Cardiol. 99(10), 1364-1368 (2007). (Pubitemid 46686633)
25. Roman RM, Wendland AE, Polanczyk CA: Myeloperoxidase and coronary arterial disease: from research to clinical practice. Arq. Bras. Cardiol. 91(1), e11-e19 (2008).
26. Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P: Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am. J. Pathol. 158(3), 879-891 (2001). (Pubitemid 32221781)
27. Naruko T, Ueda M, Haze K et al.: Neutrophil infiltration of culprit lesions in acute coronary syndromes. Circulation 106(23), 2894-2900 (2002). (Pubitemid 35424738)
28. Rudolph V, Steven D, Gehling UM et al.: Coronary plaque injury triggers neutrophil activation in patients with coronary artery disease. Free Radic. Biol. Med. 42(4), 460-465 (2007). (Pubitemid 46162115)
29. Zhang C, Reiter C, Eiserich JP et al.: l-arginine chlorination products inhibit endothelial nitric oxide production. J. Biol. Chem. 276(29), 27159-27165 (2001).
30. Zhang C, Yang J, Jacobs JD, Jennings LK: Interaction of myeloperoxidase with vascular NAD(P)H oxidase-derived reactive oxygen species in vasculature: implications for vascular diseases. Am. J. Physiol. Heart Circ. Physiol. 285(6), H2563-H2572 (2003). (Pubitemid 37443074)
31. Vita JA, Brennan ML, Gokce N et al.: Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation 110(9), 1134-1139 (2004). (Pubitemid 39319014)
32. Widlansky ME, Gokce N, Keaney JF Jr, Vita JA: The clinical implications of endothelial dysfunction. J. Am. Coll. Cardiol. 42(7), 1149-1160 (2003). (Pubitemid 37188333)
33. Vita JA, Keaney JF Jr: Endothelial function: a barometer for cardiovascular risk. Circulation 106(6), 640-642 (2002). (Pubitemid 34851918)
34. Podrez EA, Schmitt D, Hoff HF, Hazen SL: Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro. J. Clin. Invest. 103(11), 1547-1560(1999).
35. Yoshida H: [Front line of oxidized lipoproteins: role of oxidized lipoproteins in atherogenesis and cardiovascular disease risk]. Rinsho. Byori. 58(6), 622-630 (2010).
36. Anselmi M, Garbin U, Agostoni P et al.: Plasma levels of oxidized-low-density lipoproteins are higher in patients with unstable angina and correlated with angiographic coronary complex plaques. Atherosclerosis 185(1), 114-120 (2006). (Pubitemid 43117557)
37. Roman RM, Camargo PV, Borges FK, Rossini AP, Polanczyk CA: Prognostic value of myeloperoxidase in coronary artery disease: comparison of unstable and stable angina patients. Coron. Artery Dis. 21(3), 129-136 (2010).