Complex fractionated atrial electrograms a worthwhile target for ablation of atrial fibrillation?

Circulation: Arrhythmia and Electrophysiology

Volumn 4, Issue 2, 2011, Pages 117-118

  Latchamsetty, Rakesh ^a   Morady, Fred ^a  

^a UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT THERAPY; CATHETER ABLATION; COMPLEX FRACTIONATED ATRIAL ELECTROGRAM; EDITORIAL; ELECTROCARDIOGRAPHY; FLUOROSCOPY; HEART ATRIUM FIBRILLATION; HUMAN; META ANALYSIS (TOPIC); PERIODICITY; PRIORITY JOURNAL; PULMONARY VEIN ISOLATION; SINUS RHYTHM; HEART FUNCTION TEST; NOTE; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PULMONARY VEIN; RECURRENT DISEASE; TIME; TREATMENT OUTCOME;

ATRIAL FIBRILLATION; CATHETER ABLATION; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; HUMANS; PREDICTIVE VALUE OF TESTS; PULMONARY VEINS; RECURRENCE; TIME FACTORS; TREATMENT OUTCOME;

EID: 79958779989     PISSN: 19413149     EISSN: 19413084     Source Type: Journal    
DOI: 10.1161/CIRCEP.111.962274     Document Type: Editorial

References (16)

1. Haissaguerre M, Jais P, Shah DC, Takahashi A, Hocini M, Quiniou G, Garrigue S, Le Mouroux A, Le Metayer P, Clementy J. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339:659-666. (Pubitemid 28402090)
2. Chen SA, Hsieh MH, Tai CT, Tsai CF, Prakash VS, Yu WC, Hsu TL, Ding YA, Chang MS. Initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins: electrophysiological characteristics, pharmacological responses, and effects of radiofrequency ablation. Circulation. 1999;100:1879-1886. (Pubitemid 29511141)
3. Pappone C, Rosanio S, Oreto G, Tocchi M, Gugliotta F, Vicedomini G, Salvati A, Dicandia C, Mazzone P, Santinelli V, Gulletta S, Chierchia S. Circumferential radiofrequency ablation of pulmonary vein ostia: a new anatomic approach for curing atrial fibrillation. Circulation. 2000;102: 2619-2628.
4. Oral H, Knight BP, Tada H, Ozaydin M, Chugh A, Hassan S, Scharf C, Lai SW, Greenstein R, Pelosi F Jr, Strickberger SA, Morady F. Pulmonary vein isolation for paroxysmal and persistent atrial fibrillation. Circulation. 2002;105:1077-1081. (Pubitemid 34212617)
5. Oral H, Pappone C, Chugh A, Good E, Bogun F, Pelosi F Jr, Bates ER, Lehmann MH, Vicedomini G, Augello G, Agricola E, Sala S, Santinelli V, Morady F. Circumferential pulmonary-vein ablation for chronic atrial fibrillation. N Engl J Med. 2006;354:934-941.
6. Nademanee K, McKenzie J, Kosar E, Schwab M, Sunsaneewitayakul B, Vasavakul T, Khunnawat C, Ngarmukos T. A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate. J Am Coll Cardiol. 2004;43:2044-2053. (Pubitemid 38686799)
7. C, Bary CV, Kolb C, Karch M, Zrenner B, Deisenhofer I. Electrogram-guided substrate ablation with or without pulmonary vein isolation in patients with persistent atrial fibrillation. Europace. 2008;10:1281-1287.
8. Oral H, Chugh A, Good E, Wimmer A, Dey S, Gadeela N, Sankaran S, Crawford T, Sarrazin JF, Kuhne M, Chalfoun N, Wells D, Frederick M, Fortino J, Benloucif-Moore S, Jongnarangsin K, Pelosi F Jr, Bogun F, Morady F. Radiofrequency catheter ablation of chronic atrial fibrillation guided by complex electrograms. Circulation. 2007;115:2606-2612. (Pubitemid 46791358)
9. Li W-J, Bai Y-Y, Zhang H-Y, Tang R-B, Miao C-L, Sang C-H, Yin X-D, Dong J-Z, Ma C-S. Additional ablation of complex fractionated atrial electrograms (CFAEs) after pulmonary vein isolation (PVAI) in patients with atrial fibrillation: a meta-analysis. Circ Arrhythm Electrophysiol. 2011;4:143-148.
10. Jais P, Haissaguerre M, Shah DC, Chouairi S, Clementy J. Regional disparities of endocardial atrial activation in paroxysmal atrial fibrillation. Pacing Clin Electrophysiol. 1996;19:1998-2003. (Pubitemid 26398495)
11. Kalifa J, Tanaka K, Zaitsev AV, Warren M, Vaidyanathan R, Auerbach D, Pandit S, Vikstrom KL, Ploutz-Snyder R, Talkachou A, Atienza F, Guiraudon G, Jalife J, Berenfeld O. Mechanisms of wave fractionation at boundaries of high-frequency excitation in the posterior left atrium of the isolated sheep heart during atrial fibrillation. Circulation. 2006;113: 626-633.
12. Chang SH, Ulfarsson M, Chugh A, Yoshida K, Jongnarangsin K, Crawford T, Good E, Pelosi F Jr, Bogun F, Morady F, Oral H. Time- and frequency-domain characteristics of atrial electrograms during sinus rhythm and atrial fibrillation. J Cardiovasc Electrophysiol. 2011; published online ahead of print February 18, 2011.
13. Lin J, Scherlag BJ, Zhou J, Lu Z, Patterson E, Jackman WM, Lazzara R, Po SS. Autonomic mechanism to explain complex fractionated atrial electrograms (CFAE). J Cardiovasc Electrophysiol. 2007;18:1197-1205. (Pubitemid 47609881)
14. Jalife J, Berenfeld O, Mansour M. Mother rotors and fibrillatory conduction: a mechanism of atrial fibrillation. Cardiovasc Res. 2002;54: 204-216. (Pubitemid 34327901)
15. Segerson NM, Daccarett M, Badger TJ, Shabaan A, Akoum N, Fish EN, Rao S, Burgon NS, Adjei-Poku Y, Kholmovski E, Vijayakumar S, DiBella EV, MacLeod RS, Marrouche NF. Magnetic resonance imaging-confirmed ablative debulking of the left atrial posterior wall and septum for treatment of persistent atrial fibrillation: rationale and initial experience. J Cardiovasc Electrophysiol. 2010;21:126-132.
16. Nademanee K, Oketani N. The role of complex fractionated atrial elec-trograms in atrial fibrillation ablation moving to the beat of a different drum. J Am Coll Cardiol. 2009;53:790-791.