Comparative simulations of neutron dose in soft tissue and phantom materials for proton and carbon ion therapy with actively scanned beams

Medical Physics

Volumn 38, Issue 6, 2011, Pages 3149-3156

  Hälg, Roger A ^a   Besserer, Jrgen ^b   Schneider, Uwe ^b,c  

^a TRIEMLI HOSPITAL   (Switzerland)

^b Radiotherapy Hirslanden AG   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

carbon ion therapy; Monte Carlo; proton therapy; secondary neutrons; tissue equivalence

Indexed keywords

CARBON; DOSIMETRY; ION BEAMS; IONS; MONTE CARLO METHODS; NEUTRON IRRADIATION; NEUTRONS; PHANTOMS; TISSUE;

CARBON ION THERAPY; CLINICAL ENVIRONMENTS; COMPARATIVE SIMULATION; MONOENERGETIC PROTONS; NEUTRON AMBIENT DOSE EQUIVALENT; PROTON THERAPY; SECONDARY NEUTRONS; TISSUE EQUIVALENCE;

PROTON BEAM THERAPY;

EID: 79958777472     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.3584196     Document Type: Article

References (22)

1. X. G. Xu, B. Bednarz, and H. Paganetti, A review of dosimetry studies on external-beam radiation treatment with respect to second cancer induction., Phys. Med. Biol. 53, R193-R241 (2008). 10.1088/0031-9155/53/13/R01 (Pubitemid 352020053)
2. P. J. Binns and J. H. Hough, Secondary dose exposures during 200 MeV proton therapy., Radiat. Prot. Dosim. 70, 441-444 (1997). (Pubitemid 27182611)
3. X. Yan, U. Titt, A. M. Koehler, and W. D. Newhauser, Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field., Nucl. Instrum. Methods Phys. Res. A 476, 429-434 (2002). 10.1016/S0168-9002(01)01483-8 (Pubitemid 33149635)
4. S. C. Roy and G. A. Sandison, Scattered neutron dose equivalent to a fetus from proton therapy of the mother., Radiat. Phys. Chem. 71, 997-998 (2004). 10.1016/j.radphyschem.2004.05.025 (Pubitemid 39119747)
5. G. Mesoloras, G. A. Sandison, R. D. Stewart, J. B. Farr, and W. C. Hsi, Neutron scattered dose equivalent to a fetus from proton radiotherapy of the mother., Med. Phys. 33, 2479-2490 (2006). 10.1118/1.2207147 (Pubitemid 43967236)
6. R. Tayama, Y. Fujita, M. Tadokoro, H. Fujimaki, T. Sakae, and T. Terunuma, Measurement of neutron dose distribution for a passive scattering nozzle at the Proton Medical Research Center (PMRC)., Nucl. Instrum. Methods Phys. Res. A 564, 532-536 (2006). 10.1016/j.nima.2006.04.028 (Pubitemid 44051639)
7. A. Wroe, A. Rosenfeld, and R. Schulte, Out-of-field dose equivalents delivered by proton therapy of prostate cancer., Med. Phys. 34, 3449-3456 (2007). 10.1118/1.2759839 (Pubitemid 47339741)
8. U. Schneider, S. Agosteo, E. Pedroni, and J. Besserer, Secondary neutron dose during proton therapy using spot scanning., Int. J. Radiat. Oncol. Biol. Phys. 53, 244-251 (2002). 10.1016/S0360-3016(01)02826-7 (Pubitemid 34465830)
9. M. Yoon, S. H. Ahn, J. Kim, D. H. Shin, S. Y. Park, S. B. Lee, K. H. Shin, and K. H. Cho, Radiation-induced cancers from modern radiotherapy techniques: Intensity-modulated radiotherapy versus proton therapy., Int. J. Radiat. Oncol. Biol. Phys. 77, 1477-1485 (2010). 10.1016/j.ijrobp.2009.07.011
10. G. Battistoni, F. Cerutti, A. Fass, A. Ferrari, S. Muraro, J. Ranft, S. Roesler, and P. R. Sala, The FLUKA code: Description and benchmarking., Hadronic Shower Simulation Workshop (American Institute of Physics, Melville, New York, 2007), Vol. 896, pp. 31-49.
11. A. Fass, A. Ferrari, J. Ranft, and P. Sala, FLUKA: A multi-particle transport code., Tech. Rep. CERN-2005-10, INFNTC-0511, SLAC-R-773, CERN - Organisation europenne pour la recherche nucleaireEuropean organization for nuclear research (2005).
12. V. Vlachoudis, FLAIR: A powerful but user friendly graphical interface for FLUKA., in Proceedings of International Conference on Mathematics, Computational Methods and Reactor Physics, (M and C, Saratoga Springs, NY, 2009).
13. F. Sommerer, K. Parodi, A. Ferrari, K. Poljanc, W. Enghardt, and H. Aiginger, Investigating the accuracy of the FLUKA code for transport of therapeutic ion beams in matter., Phys. Med. Biol. 51, 4385-4398 (2006). 10.1088/0031-9155/51/17/017 (Pubitemid 44261851)
14. M. J. Litzkow, M. Livny, and M. W. Mutka, Condor-a hunter of idle workstations., in Proceedings of the Eighth International Conference on Distributed Computing Systems (Cat. No. 88CH2541-1) (IEEE Comput. Soc. Press, Washington, DC, 2008), p. 104.
15. A. J. Lomax, T. Bohringer, A. Bolsi, D. Coray, F. Emert, G. Goitein, M. Jermann, S. X. Lin, E. Pedroni, H. Rutz, O. Stadelmann, B. Timmermann, J. Verwey, and D. C. Weber, Treatment planning and verification of proton therapy using spot scanning: Initial experiences., Med. Phys. 31, 3150-3157 (2004). 10.1118/1.1779371 (Pubitemid 39552703)
16. S. E. Combs, O. Jaekel, T. Haberer, and J. Debus, Particle therapy at the Heidelberg Ion Therapy Center (HIT) - Integrated research-driven university-hospital-based radiation oncology service in Heidelberg, Germany., Radiother. Oncol. 95, 41-44 (2010). 10.1016/j.radonc.2010.02.016
17. J. F. Janni, Energy loss, range, path length, time-of-flight, straggling, multiple scattering, and nuclear interaction probability: In two parts. Part 1. For 63 compounds Part 2. For elements 1 Z 92., At. Data Nucl. Data Tables 27, 147-339 (1982). 10.1016/0092-640X(82)90004-3
18. International Commission on Radiological Protection, Reference man: Anatomical, physiological and metabolic characteristics., in ICRP Report 23 (Pergamon, Oxford, 1975).
19. M. Pelliccioni, Overview of fluence-to-effective dose and fluence-to ambient dose equivalent conversion coefficients for high energy radiation calculated using the FLUKA code., Radiat. Prot. Dosim. 88, 279-297 (2000). (Pubitemid 30646840)
20. S. Roesler and G. R. Stevenson, deq99.f - A FLUKA user-routine converting fluence into effective dose and ambient dose equivalent., Technical Note CERN-SC-2006-070-RP-TN EDMS Document Number: 809389 v.1, CERN - European organization for nuclear research Safety Commission, CERN, 1211 Geneva 23, Switzerland (2006).
21. International Commission on Radiological Protection, The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103., Ann. ICRP 37, 1-332 (2007).
22. S. Dowdell, B. Clasie, A. Wroe, S. Guatelli, P. Metcalfe, R. Schulte, and A. Rosenfeld, Tissue equivalency of phantom materials for neutron dosimetry in proton therapy., Med. Phys. 36, 5412-5419 (2009). 10.1118/1.3250857